Gene: ENSG00000019549 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000019549
Transcript Identifier
ENST00000020945
Gene Type
Coding gene
Location
8 : 48918807-48921265 : negative

Family Information

Homologous gene family
HOM03P000007
(1601 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P021460
(5 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
snail family zinc finger 2

Identifiers

Type Value
pidENSP00000020945
HGNC11094
UniprotO43623

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IMP
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001649
IEP
Genome Projectosteoblast differentiation
GO:0001837
IMP
Genome Projectepithelial to mesenchymal transition
GO:0003198
ISS
IEA
Genome Projectepithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003273
ISS
IEA
Genome Projectcell migration involved in endocardial cushion formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006933
IEA
Genome Projectnegative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007219
IMP
Genome ProjectNotch signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0009314
IEA
Genome Projectresponse to radiation
GO:0010839
IDA
Genome Projectnegative regulation of keratinocyte proliferation
GO:0010957
IDA
Genome Projectnegative regulation of vitamin D biosynthetic process
GO:0014032
IMP
Genome Projectneural crest cell development
GO:0016477
IEA
Genome Projectcell migration
GO:0030335
IMP
Genome Projectpositive regulation of cell migration
GO:0032331
IMP
Genome Projectnegative regulation of chondrocyte differentiation
GO:0032642
IMP
Genome Projectregulation of chemokine production
GO:0033629
IC
Genome Projectnegative regulation of cell adhesion mediated by integrin
GO:0035066
IEA
Genome Projectpositive regulation of histone acetylation
GO:0035414
IDA
Genome Projectnegative regulation of catenin import into nucleus
GO:0035921
IMP
Genome Projectdesmosome disassembly
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043473
IMP
Genome Projectpigmentation
GO:0043518
IMP
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044344
IEA
Genome Projectcellular response to fibroblast growth factor stimulus
GO:0045600
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045667
IMP
Genome Projectregulation of osteoblast differentiation
GO:0050872
IEA
Genome Projectwhite fat cell differentiation
GO:0060021
IEA
Genome Projectpalate development
GO:0060070
IMP
Genome Projectcanonical Wnt signaling pathway
GO:0060429
ISS
IEA
Genome Projectepithelium development
GO:0060536
IEA
Genome Projectcartilage morphogenesis
GO:0060693
IEA
Genome Projectregulation of branching involved in salivary gland morphogenesis
GO:0070563
IDA
Genome Projectnegative regulation of vitamin D receptor signaling pathway
GO:0071364
IDA
Genome Projectcellular response to epidermal growth factor stimulus
GO:0071479
IEA
Genome Projectcellular response to ionizing radiation
GO:0090090
IDA, IMP
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:1900387
IMP
Genome Projectnegative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter
GO:1902230
IMP
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000647
IEA
Genome Projectnegative regulation of stem cell proliferation
GO:2000810
IMP
Genome Projectregulation of bicellular tight junction assembly
GO:2000811
IMP
Genome Projectnegative regulation of anoikis
GO:2001240
ISS
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001078
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like

No MapMan annotations defined for this gene.