Gene: ENSG00000012061 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000012061
Transcript Identifier
ENST00000013807
Gene Type
Coding gene
Location
19 : 45413548-45423374 : negative

Family Information

Homologous gene family
HOM03P002112
(40 genes in 36 species)
specific family

Descriptions

gene_descr
excision repair cross-complementation group 1

Identifiers

Type Value
pidENSP00000013807
HGNC3433
UniprotP07992

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000718
TAS
Genome Projectnucleotide-excision repair, DNA damage removal
GO:0000720
IEA
Genome Projectpyrimidine dimer repair by nucleotide-excision repair
GO:0001302
IEA
Genome Projectreplicative cell aging
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006289
IDA, IGI
TAS
Genome Projectnucleotide-excision repair
GO:0006295
IMP
Genome Projectnucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296
IMP
Genome Projectnucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006302
IEA
Genome Projectdouble-strand break repair
GO:0006310
IGI
Genome ProjectDNA recombination
GO:0006312
IMP
Genome Projectmitotic recombination
GO:0006949
IEA
Genome Projectsyncytium formation
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0006979
IMP
Genome Projectresponse to oxidative stress
GO:0007281
IEA
Genome Projectgerm cell development
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0008283
IEA
Genome Projectcell proliferation
GO:0008584
IEA
Genome Projectmale gonad development
GO:0009650
IEA
Genome ProjectUV protection
GO:0009744
IEA
Genome Projectresponse to sucrose
GO:0010165
IEA
Genome Projectresponse to X-ray
GO:0010259
IEA
Genome Projectmulticellular organismal aging
GO:0032205
IMP
Genome Projectnegative regulation of telomere maintenance
GO:0035166
IEA
Genome Projectpost-embryonic hemopoiesis
GO:0035264
IEA
Genome Projectmulticellular organism growth
GO:0036297
IEA
Genome Projectinterstrand cross-link repair
GO:0045190
IEA
Genome Projectisotype switching
GO:0048468
IEA
Genome Projectcell development
GO:0048477
IEA
Genome Projectoogenesis
GO:0048568
IEA
Genome Projectembryonic organ development
GO:0051276
IEA
Genome Projectchromosome organization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001094
IEA
Genome ProjectTFIID-class transcription factor binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003684
IDA
IEA
Genome Projectdamaged DNA binding
GO:0003697
IDA
Genome Projectsingle-stranded DNA binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0000014
IDA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0043566
IDA
Genome Projectstructure-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000109
IDA
Genome Projectnucleotide-excision repair complex
GO:0000110
IDA
Genome Projectnucleotide-excision repair factor 1 complex
GO:0000784
IDA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005669
IEA
Genome Projecttranscription factor TFIID complex
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0070522
IDA
Genome ProjectERCC4-ERCC1 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003583Helix-hairpin-helix DNA-binding motif, class 1
IPR004579ERCC1/RAD10/SWI10 family
IPR010994RuvA domain 2-like
IPR011335Restriction endonuclease type II-like

No MapMan annotations defined for this gene.