Gene: ENSG00000011485 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000011485
Transcript Identifier
ENST00000012443
Gene Type
Coding gene
Location
19 : 46347097-46390346 : positive

Family Information

Homologous gene family
HOM03P000043
(553 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001863
(34 genes in 32 species)
specific family

Descriptions

gene_descr
protein phosphatase 5, catalytic subunit

Identifiers

Type Value
pidENSP00000012443
HGNC9322
UniprotP53041
UniprotA0A024R0Q7

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001933
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0006470
TAS, IEA
Genome Projectprotein dephosphorylation
GO:0010288
IEA
Genome Projectresponse to lead ion
GO:0016576
IEA
Genome Projecthistone dephosphorylation
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0051259
IEA
Genome Projectprotein oligomerization
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0060548
IEA
Genome Projectnegative regulation of cell death
GO:0070301
IEA
Genome Projectcellular response to hydrogen peroxide
GO:0071276
IEA
Genome Projectcellular response to cadmium ion
GO:1901215
IEA
Genome Projectnegative regulation of neuron death
GO:2000324
IEA
Genome Projectpositive regulation of glucocorticoid receptor signaling pathway
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006351
TAS
Genome Projecttranscription, DNA-templated
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007067
TAS
Genome Projectmitotic nuclear division
GO:0007165
IMP
Genome Projectsignal transduction
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001965
IEA
Genome ProjectG-protein alpha-subunit binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0004721
ISS
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0008017
IEA
Genome Projectmicrotubule binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0031072
IEA
Genome Projectheat shock protein binding
GO:0004722
TAS
Genome Projectprotein serine/threonine phosphatase activity
GO:0004871
IMP
Genome Projectsignal transducer activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008289
IEA
Genome Projectlipid binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
TAS, IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IEA
Genome Projectcytosol
GO:0043005
IEA
Genome Projectneuron projection
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043204
IEA
Genome Projectperikaryon
GO:0071944
IEA
Genome Projectcell periphery
GO:1990635
IEA
Genome Projectproximal dendrite
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0016020
IEA
Genome Projectmembrane
GO:0043231
IDA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001440Tetratricopeptide repeat 1
IPR004843Calcineurin-like phosphoesterase domain, apaH type
IPR006186Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR011236Serine/threonine protein phosphatase 5
IPR011990Tetratricopeptide-like helical domain
IPR013026Tetratricopeptide repeat-containing domain
IPR013235PPP domain
IPR019734Tetratricopeptide repeat
IPR029052Metallo-dependent phosphatase-like

No MapMan annotations defined for this gene.