Gene: ENSG00000008438 (Homo sapiens)

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Gene Identifier
ENSG00000008438
Transcript Identifier
ENST00000008938
Gene Type
Coding gene
Location
19 : 46019238-46023021 : negative

Family Information

Homologous gene family
HOM03P004528
(21 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P017943
(5 genes in 3 species)
specific family

Descriptions

gene_descr
peptidoglycan recognition protein 1

Identifiers

Type Value
pidENSP00000008938
HGNC8904
UniprotO75594

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002221
IDA
Genome Projectpattern recognition receptor signaling pathway
GO:0002376
IEA
Genome Projectimmune system process
GO:0006955
TAS
Genome Projectimmune response
GO:0009253
IEA
Genome Projectpeptidoglycan catabolic process
GO:0016045
IDA
Genome Projectdetection of bacterium
GO:0032689
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032827
IEA
Genome Projectnegative regulation of natural killer cell differentiation involved in immune response
GO:0042742
IEA
Genome Projectdefense response to bacterium
GO:0044117
IEA
Genome Projectgrowth of symbiont in host
GO:0045087
NAS, IEA
Genome Projectinnate immune response
GO:0050728
IEA
Genome Projectnegative regulation of inflammatory response
GO:0050830
IDA
Genome Projectdefense response to Gram-positive bacterium

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008745
IEA
Genome ProjectN-acetylmuramoyl-L-alanine amidase activity
GO:0016019
IDA
Genome Projectpeptidoglycan receptor activity
GO:0042834
IDA
Genome Projectpeptidoglycan binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
NAS, IEA
Genome Projectextracellular region
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002502N-acetylmuramoyl-L-alanine amidase domain
IPR006619Peptidoglycan recognition protein family domain, metazoa/bacteria
IPR015510Peptidoglycan recognition protein
IPR017331Peptidoglycan recognition protein, PGRP-S

No MapMan annotations defined for this gene.