Gene: ENSG00000007168 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000007168
Transcript Identifier
ENST00000397195
Gene Type
Coding gene
Location
17 : 2638289-2681802 : positive

Family Information

Homologous gene family
HOM03P000003
(2229 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P006022
(14 genes in 13 species)
specific family

Descriptions

gene_descr
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

Identifiers

Type Value
pidENSP00000380378
HGNC8574
UniprotP43034

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000132
IMP
IEA
Genome Projectestablishment of mitotic spindle orientation
GO:0000226
ISS
IEA
Genome Projectmicrotubule cytoskeleton organization
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0001667
IEA
Genome Projectameboidal-type cell migration
GO:0001675
ISS
IEA
Genome Projectacrosome assembly
GO:0001764
IMP
ISS
IEA
Genome Projectneuron migration
GO:0001961
IEA
Genome Projectpositive regulation of cytokine-mediated signaling pathway
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007017
IDA
IEA
Genome Projectmicrotubule-based process
GO:0007049
IEA
Genome Projectcell cycle
GO:0007067
IEA
Genome Projectmitotic nuclear division
GO:0007097
IBA
IEA
Genome Projectnuclear migration
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007268
ISS
IEA
Genome Projectsynaptic transmission
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007281
IBA
Genome Projectgerm cell development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007405
ISS
IEA
Genome Projectneuroblast proliferation
GO:0007420
IEA
Genome Projectbrain development
GO:0007611
ISS
IEA
Genome Projectlearning or memory
GO:0008090
ISS, IBA
IEA
Genome Projectretrograde axon cargo transport
GO:0008344
IMP
Genome Projectadult locomotory behavior
GO:0009306
IEA
Genome Projectprotein secretion
GO:0010977
IEA
Genome Projectnegative regulation of neuron projection development
GO:0016042
IEA
Genome Projectlipid catabolic process
GO:0016477
IEA
Genome Projectcell migration
GO:0017145
IEA
Genome Projectstem cell division
GO:0019226
ISS
IEA
Genome Projecttransmission of nerve impulse
GO:0021540
IMP
Genome Projectcorpus callosum morphogenesis
GO:0021766
ISS
IEA
Genome Projecthippocampus development
GO:0021819
ISS
IEA
Genome Projectlayer formation in cerebral cortex
GO:0021895
IEA
Genome Projectcerebral cortex neuron differentiation
GO:0021987
IMP
Genome Projectcerebral cortex development
GO:0030036
ISS
IEA
Genome Projectactin cytoskeleton organization
GO:0030154
IEA
Genome Projectcell differentiation
GO:0031023
IMP
Genome Projectmicrotubule organizing center organization
GO:0036035
IEA
Genome Projectosteoclast development
GO:0040019
IEA
Genome Projectpositive regulation of embryonic development
GO:0042249
IEA
Genome Projectestablishment of planar polarity of embryonic epithelium
GO:0043087
IEA
Genome Projectregulation of GTPase activity
GO:0043622
IEA
Genome Projectcortical microtubule organization
GO:0045773
IEA
Genome Projectpositive regulation of axon extension
GO:0045931
IEA
Genome Projectpositive regulation of mitotic cell cycle
GO:0046329
IEA
Genome Projectnegative regulation of JNK cascade
GO:0046469
ISS
Genome Projectplatelet activating factor metabolic process
GO:0047496
ISS, IBA
IEA
Genome Projectvesicle transport along microtubule
GO:0048854
IMP
Genome Projectbrain morphogenesis
GO:0050885
IMP
Genome Projectneuromuscular process controlling balance
GO:0051081
IEA
Genome Projectnuclear envelope disassembly
GO:0051130
IEA
Genome Projectpositive regulation of cellular component organization
GO:0051301
IEA
Genome Projectcell division
GO:0051660
IEA
Genome Projectestablishment of centrosome localization
GO:0060117
IEA
Genome Projectauditory receptor cell development
GO:0061003
IEA
Genome Projectpositive regulation of dendritic spine morphogenesis
GO:0070507
IEA
Genome Projectregulation of microtubule cytoskeleton organization
GO:0090102
IEA
Genome Projectcochlea development
GO:0090176
IEA
Genome Projectmicrotubule cytoskeleton organization involved in establishment of planar polarity
GO:2000574
IBA
Genome Projectregulation of microtubule motor activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
ISS, IBA
Genome Projectmicrotubule binding
GO:0008201
ISS
Genome Projectheparin binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0034452
ISS
Genome Projectdynactin binding
GO:0042803
ISS
IEA
Genome Projectprotein homodimerization activity
GO:0043274
ISS
Genome Projectphospholipase binding
GO:0045502
IDA
IEA
Genome Projectdynein binding
GO:0045505
IEA
Genome Projectdynein intermediate chain binding
GO:0051219
ISS
IEA
Genome Projectphosphoprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000235
IDA
Genome Projectastral microtubule
GO:0000776
IDA
Genome Projectkinetochore
GO:0005634
IEA
Genome Projectnucleus
GO:0005635
IDA
IEA
Genome Projectnuclear envelope
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005813
IDA
ISS
Genome Projectcentrosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005819
IEA
Genome Projectspindle
GO:0005829
ISS
TAS, IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005871
IEA
Genome Projectkinesin complex
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005875
IDA
IEA
Genome Projectmicrotubule associated complex
GO:0005938
IDA
Genome Projectcell cortex
GO:0015630
IEA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0030424
IEA
Genome Projectaxon
GO:0030426
IEA
Genome Projectgrowth cone
GO:0031252
ISS
IEA
Genome Projectcell leading edge
GO:0031512
ISS
IEA
Genome Projectmotile primary cilium
GO:0031965
IEA
Genome Projectnuclear membrane
GO:0031982
IEA
Genome Projectvesicle
GO:0043005
IEA
Genome Projectneuron projection
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0048471
ISS
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001680WD40 repeat
IPR006594LIS1 homology motif
IPR015943WD40/YVTN repeat-like-containing domain
IPR017252Dynein regulator LIS1
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site
IPR020472G-protein beta WD-40 repeat

No MapMan annotations defined for this gene.