Gene: ENSG00000006747 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000006747
Transcript Identifier
ENST00000297029
Gene Type
Coding gene
Location
7 : 12570787-12652715 : positive

Family Information

Homologous gene family
HOM03P000775
(73 genes in 23 species)
specific family
Orthologous gene family
ORTHO03P000870
(42 genes in 21 species)
specific family

Descriptions

gene_descr
scinderin

Identifiers

Type Value
pidENSP00000297029
HGNC21695
UniprotQ9Y6U3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0017156
ISS
Genome Projectcalcium ion-dependent exocytosis
GO:0032330
ISS
Genome Projectregulation of chondrocyte differentiation
GO:0042989
IMP
Genome Projectsequestering of actin monomers
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0045010
ISS
Genome Projectactin nucleation
GO:0045654
IMP
Genome Projectpositive regulation of megakaryocyte differentiation
GO:0051014
IMP
IEA
Genome Projectactin filament severing
GO:0051047
ISS
Genome Projectpositive regulation of secretion
GO:0051127
IMP
Genome Projectpositive regulation of actin nucleation
GO:0051693
IMP
IEA
Genome Projectactin filament capping

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001786
ISS
Genome Projectphosphatidylserine binding
GO:0003779
ISS
TAS, IEA
Genome Projectactin binding
GO:0005509
ISS
TAS, IEA
Genome Projectcalcium ion binding
GO:0005545
TAS
Genome Project1-phosphatidylinositol binding
GO:0005546
ISS
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0051015
ISS
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005903
IEA
Genome Projectbrush border
GO:0005938
ISS
Genome Projectcell cortex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR007122Villin/Gelsolin
IPR007123Gelsolin-like domain
IPR029006ADF-H/Gelsolin-like domain
IPR030012Adseverin

No MapMan annotations defined for this gene.