Gene: ENSG00000005961 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000005961
Transcript Identifier
ENST00000262407
Gene Type
Coding gene
Location
17 : 44372364-44389473 : negative

Family Information

Homologous gene family
HOM03P002672
(35 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P009315
(9 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Identifiers

Type Value
pidENSP00000262407
HGNC6138
UniprotP08514

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002576
TAS
Genome Projectplatelet degranulation
GO:0002687
IEA
Genome Projectpositive regulation of leukocyte migration
GO:0007155
TAS, IEA
Genome Projectcell adhesion
GO:0007160
IEA
Genome Projectcell-matrix adhesion
GO:0007229
IDA
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007596
TAS
Genome Projectblood coagulation
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030198
TAS
Genome Projectextracellular matrix organization
GO:0070527
IEA
Genome Projectplatelet aggregation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050840
IEA
Genome Projectextracellular matrix binding
GO:0070051
IEA
Genome Projectfibrinogen binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0005925
IEA
Genome Projectfocal adhesion
GO:0008305
IEA
Genome Projectintegrin complex
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031092
TAS
Genome Projectplatelet alpha granule membrane
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0072562
IDA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000413Integrin alpha chain
IPR013517FG-GAP repeat
IPR013519Integrin alpha beta-propellor
IPR013649Integrin alpha-2
IPR018184Integrin alpha chain, C-terminal cytoplasmic region, conserved site

No MapMan annotations defined for this gene.