Gene: ENSG00000005249 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000005249
Transcript Identifier
ENST00000265717
Gene Type
Coding gene
Location
7 : 107044908-107159582 : positive

Family Information

Homologous gene family
HOM03P000470
(100 genes in 25 species)
specific family
Orthologous gene family
ORTHO03P000404
(51 genes in 22 species)
specific family

Descriptions

gene_descr
protein kinase, cAMP-dependent, regulatory, type II, beta

Identifiers

Type Value
pidENSP00000265717
HGNC9392
UniprotP31323
UniprotA0A024R712

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001932
IEA
Genome Projectregulation of protein phosphorylation
GO:0006631
IEA
Genome Projectfatty acid metabolic process
GO:0007612
IEA
Genome Projectlearning
GO:0016310
IEA
Genome Projectphosphorylation
GO:0045859
IEA
Genome Projectregulation of protein kinase activity
GO:0097332
IEA
Genome Projectresponse to antipsychotic drug
GO:0097338
IEA
Genome Projectresponse to clozapine
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0003091
TAS
Genome Projectrenal water homeostasis
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0006833
TAS
Genome Projectwater transport
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007173
TAS
Genome Projectepidermal growth factor receptor signaling pathway
GO:0007202
TAS
Genome Projectactivation of phospholipase C activity
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008543
TAS
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0034199
TAS
Genome Projectactivation of protein kinase A activity
GO:0035556
TAS
Genome Projectintracellular signal transduction
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0050796
TAS
Genome Projectregulation of insulin secretion
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0071377
TAS
Genome Projectcellular response to glucagon stimulus
GO:2000480
IDA
Genome Projectnegative regulation of cAMP-dependent protein kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008603
IDA
TAS, IEA
Genome ProjectcAMP-dependent protein kinase regulator activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0030552
IEA
Genome ProjectcAMP binding
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004862
IDA
Genome ProjectcAMP-dependent protein kinase inhibitor activity
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding
GO:0034236
IPI
Genome Projectprotein kinase A catalytic subunit binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005952
IEA
Genome ProjectcAMP-dependent protein kinase complex
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043197
ISS
IEA
Genome Projectdendritic spine
GO:0043198
ISS
IEA
Genome Projectdendritic shaft
GO:0045121
IEA
Genome Projectmembrane raft
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097546
TAS, IEA
Genome Projectciliary base
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000595Cyclic nucleotide-binding domain
IPR003117cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
IPR012198cAMP-dependent protein kinase regulatory subunit
IPR014710RmlC-like jelly roll fold
IPR018488Cyclic nucleotide-binding, conserved site
IPR018490Cyclic nucleotide-binding-like

No MapMan annotations defined for this gene.