Gene: ENSG00000004478 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000004478
Transcript Identifier
ENST00000001008
Gene Type
Coding gene
Location
12 : 2795140-2803258 : positive

Family Information

Homologous gene family
HOM03P000050
(477 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000803
(43 genes in 32 species)
specific family

Descriptions

gene_descr
FK506 binding protein 4, 59kDa

Identifiers

Type Value
pidENSP00000001008
HGNC3720
UniprotQ02790

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000413
IDA
IEA
Genome Projectprotein peptidyl-prolyl isomerization
GO:0006457
TAS, IEA
Genome Projectprotein folding
GO:0006463
IEA
Genome Projectsteroid hormone receptor complex assembly
GO:0006825
IEA
Genome Projectcopper ion transport
GO:0007566
IEA
Genome Projectembryo implantation
GO:0010977
ISS
Genome Projectnegative regulation of neuron projection development
GO:0030521
IEA
Genome Projectandrogen receptor signaling pathway
GO:0030850
IEA
Genome Projectprostate gland development
GO:0031111
ISS
Genome Projectnegative regulation of microtubule polymerization or depolymerization
GO:0031115
IEA
Genome Projectnegative regulation of microtubule polymerization
GO:0031503
IEA
Genome Projectprotein complex localization
GO:0034605
TAS
Genome Projectcellular response to heat
GO:0046661
IEA
Genome Projectmale sex differentiation
GO:0048608
IEA
Genome Projectreproductive structure development
GO:0061077
IDA
Genome Projectchaperone-mediated protein folding
GO:1900034
TAS
Genome Projectregulation of cellular response to heat

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003755
IDA
IEA
Genome Projectpeptidyl-prolyl cis-trans isomerase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0005528
TAS
Genome ProjectFK506 binding
GO:0016853
IEA
Genome Projectisomerase activity
GO:0030674
TAS
Genome Projectprotein binding, bridging
GO:0031072
IPI
Genome Projectheat shock protein binding
GO:0032767
IEA
Genome Projectcopper-dependent protein binding
GO:0035259
IEA
Genome Projectglucocorticoid receptor binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0048156
IEA
Genome Projecttau protein binding
GO:0051219
IEA
Genome Projectphosphoprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005789
IBA
Genome Projectendoplasmic reticulum membrane
GO:0005829
ISS
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005874
IEA
Genome Projectmicrotubule
GO:0043005
IEA
Genome Projectneuron projection
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043234
IEA
Genome Projectprotein complex
GO:0044295
ISS
IEA
Genome Projectaxonal growth cone
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001179FKBP-type peptidyl-prolyl cis-trans isomerase domain
IPR011990Tetratricopeptide-like helical domain
IPR013026Tetratricopeptide repeat-containing domain
IPR013105Tetratricopeptide repeat 2
IPR019734Tetratricopeptide repeat
IPR023566Peptidyl-prolyl cis-trans isomerase, FKBP-type
IPR031212Peptidyl-prolyl cis-trans isomerase FKBP4

No MapMan annotations defined for this gene.