Gene: YLR208W (Saccharomyces cerevisiae strain S288C)

Overview top

Gene Identifier
YLR208W
Transcript Identifier
YLR208W
Gene Type
Coding gene
Location
XII : 559551-560444 : positive

Family Information

Homologous gene family
HOM02SEM000618
(66 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000693
(61 genes in 26 species)
specific family

Descriptions

gene_descr
Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress

Identifiers

Type Value
pidYLR208W
UniprotQ04491
RefSeq_mRNANM_001182095.1
EMBLBK006945
EMBLL05929
EMBLU14913
SGDS000004198

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:1904263
IMP
Genome Projectpositive regulation of TORC1 signaling
GO:1904263
IMP
Gene Ontologypositive regulation of TORC1 signaling1
GO:0043547
IDA
Genome Projectpositive regulation of GTPase activity
GO:0043547
IDA
Gene Ontologypositive regulation of GTPase activity2
GO:0051028
IEA
Genome ProjectmRNA transport
GO:0015031
IEA
Genome Projectprotein transport
GO:0090114
IMP
Genome ProjectCOPII-coated vesicle budding
GO:0090114
IMP
Gene OntologyCOPII-coated vesicle budding3 4
GO:0031081
IMP
Genome Projectnuclear pore distribution
GO:0031081
IMP
Gene Ontologynuclear pore distribution5
GO:0030433
IMP
Genome Projectubiquitin-dependent ERAD pathway
GO:0030433
IMP
Gene Ontologyubiquitin-dependent ERAD pathway6
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045893
IDA
Gene Ontologypositive regulation of transcription, DNA-templated7
GO:0016192
IEA
Genome Projectvesicle-mediated transport
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process WBGene00003806
GO:0090529
IEA
PLAZA Integrative Orthologycell septum assembly WBGene00003806
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change WBGene00003806
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process FBgn0024509
GO:0006903
IEA
PLAZA Integrative Orthologyvesicle targeting ENSG00000157020
GO:0048199
IEA
PLAZA Integrative Orthologyvesicle targeting, to, from or within Golgi ENSG00000157020
GO:0006901
IEA
PLAZA Integrative Orthologyvesicle coating ENSG00000157020
GO:0006357
IEA
PLAZA Integrative Orthologyregulation of transcription by RNA polymerase II FBgn0024509
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle ENSG00000157020
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0024509
GO:0006352
IEA
PLAZA Integrative OrthologyDNA-templated transcription, initiation FBgn0024509
GO:0035293
IEA
PLAZA Integrative Orthologychitin-based larval cuticle pattern formation FBgn0024509
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00003806
GO:0032467
IEA
PLAZA Integrative Orthologypositive regulation of cytokinesis WBGene00003806
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00003806
GO:0097305
IEA
PLAZA Integrative Orthologyresponse to alcohol FBgn0024509
GO:0097306
IEA
PLAZA Integrative Orthologycellular response to alcohol FBgn0024509
GO:0032465
IEA
PLAZA Integrative Orthologyregulation of cytokinesis WBGene00003806
GO:0035459
IEA
PLAZA Integrative Orthologycargo loading into vesicle ENSG00000157020
GO:0032506
IEA
PLAZA Integrative Orthologycytokinetic process WBGene00003806
GO:0000910
IEA
PLAZA Integrative Orthologycytokinesis WBGene00003806
GO:0090110
IEA
PLAZA Integrative Orthologycargo loading into COPII-coated vesicle ENSG00000157020
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development WBGene00003806
GO:0008363
IEA
PLAZA Integrative Orthologylarval chitin-based cuticle development FBgn0024509
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development WBGene00003806
GO:0000917
IEA
PLAZA Integrative Orthologydivision septum assembly WBGene00003806
GO:0036315
IEA
PLAZA Integrative Orthologycellular response to sterol FBgn0024509
GO:0036314
IEA
PLAZA Integrative Orthologyresponse to sterol FBgn0024509
GO:0032870
IEA
PLAZA Integrative Orthologycellular response to hormone stimulus FBgn0024509
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression FBgn0024509
GO:0048208
IEA
PLAZA Integrative OrthologyCOPII vesicle coating ENSG00000157020
GO:0048207
IEA
PLAZA Integrative Orthologyvesicle targeting, rough ER to cis-Golgi ENSG00000157020
GO:0035075
IEA
PLAZA Integrative Orthologyresponse to ecdysone FBgn0024509
GO:0035079
IEA
PLAZA Integrative Orthologypolytene chromosome puffing FBgn0024509
GO:0007062
IEA
PLAZA Integrative Orthologysister chromatid cohesion ENSG00000157020
GO:0035077
IEA
PLAZA Integrative Orthologyecdysone-mediated polytene chromosome puffing FBgn0024509
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus FBgn0024509
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle WBGene00003806
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation ENSG00000157020
GO:0010973
IEA
PLAZA Integrative Orthologypositive regulation of division septum assembly WBGene00003806
GO:0044089
IEA
PLAZA Integrative Orthologypositive regulation of cellular component biogenesis WBGene00003806
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis WBGene00003806
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus FBgn0024509
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission WBGene00003806
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000157020
GO:0006913
IEA
PLAZA Integrative Orthologynucleocytoplasmic transport WBGene00003806
GO:0051169
IEA
PLAZA Integrative Orthologynuclear transport WBGene00003806
GO:0042337
IEA
PLAZA Integrative Orthologycuticle development involved in chitin-based cuticle molting cycle FBgn0024509
GO:0002168
IEA
PLAZA Integrative Orthologyinstar larval development FBgn0024509
GO:0006367
IEA
PLAZA Integrative Orthologytranscription initiation from RNA polymerase II promoter FBgn0024509
GO:1901700
IEA
PLAZA Integrative Orthologyresponse to oxygen-containing compound FBgn0024509
GO:0042335
IEA
PLAZA Integrative Orthologycuticle development FBgn0024509
GO:1901701
IEA
PLAZA Integrative Orthologycellular response to oxygen-containing compound FBgn0024509
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0024509
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport SPBC215.15
GO:0002164
IEA
PLAZA Integrative Orthologylarval development FBgn0024509
GO:0051170
IEA
PLAZA Integrative Orthologyimport into nucleus WBGene00003806
GO:0006366
IEA
PLAZA Integrative Orthologytranscription by RNA polymerase II FBgn0024509
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation ENSG00000157020
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000157020
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process WBGene00003806
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation ENSG00000157020
GO:0017038
IEA
PLAZA Integrative Orthologyprotein import WBGene00003806
GO:2000144
IEA
PLAZA Integrative Orthologypositive regulation of DNA-templated transcription, initiation FBgn0024509
GO:0002504
IEA
PLAZA Integrative Orthologyantigen processing and presentation of peptide or polysaccharide antigen via MHC class II ENSG00000157020
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization ENSG00000157020
GO:0072594
IEA
PLAZA Integrative Orthologyestablishment of protein localization to organelle WBGene00003806
GO:0002474
IEA
PLAZA Integrative Orthologyantigen processing and presentation of peptide antigen via MHC class I ENSG00000157020
GO:0071390
IEA
PLAZA Integrative Orthologycellular response to ecdysone FBgn0024509
GO:1901654
IEA
PLAZA Integrative Orthologyresponse to ketone FBgn0024509
GO:1901655
IEA
PLAZA Integrative Orthologycellular response to ketone FBgn0024509
GO:0043254
IEA
PLAZA Integrative Orthologyregulation of protein complex assembly FBgn0024509
GO:1901893
IEA
PLAZA Integrative Orthologypositive regulation of cell septum assembly WBGene00003806
GO:0009266
IEA
PLAZA Integrative Orthologyresponse to temperature stimulus FBgn0024509
GO:1901891
IEA
PLAZA Integrative Orthologyregulation of cell septum assembly WBGene00003806
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization ENSG00000157020
GO:0031334
IEA
PLAZA Integrative Orthologypositive regulation of protein complex assembly FBgn0024509
GO:0035017
IEA
PLAZA Integrative Orthologycuticle pattern formation FBgn0024509
GO:0033993
IEA
PLAZA Integrative Orthologyresponse to lipid FBgn0024509
GO:0140014
IEA
PLAZA Integrative Orthologymitotic nuclear division WBGene00003806
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division WBGene00003806
GO:0071396
IEA
PLAZA Integrative Orthologycellular response to lipid FBgn0024509
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance FBgn0024509
GO:0051781
IEA
PLAZA Integrative Orthologypositive regulation of cell division WBGene00003806
GO:0034605
IEA
PLAZA Integrative Orthologycellular response to heat FBgn0024509
GO:0009408
IEA
PLAZA Integrative Orthologyresponse to heat FBgn0024509
GO:0051302
IEA
PLAZA Integrative Orthologyregulation of cell division WBGene00003806
GO:0051301
IEA
PLAZA Integrative Orthologycell division WBGene00003806
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle WBGene00003806
GO:0045944
IEA
PLAZA Integrative Orthologypositive regulation of transcription by RNA polymerase II FBgn0024509
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle WBGene00003806
GO:0007591
IEA
PLAZA Integrative Orthologymolting cycle, chitin-based cuticle FBgn0024509
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process FBgn0024509
GO:0060261
IEA
PLAZA Integrative Orthologypositive regulation of transcription initiation from RNA polymerase II promoter FBgn0024509
GO:2000142
IEA
PLAZA Integrative Orthologyregulation of DNA-templated transcription, initiation FBgn0024509
GO:0060260
IEA
PLAZA Integrative Orthologyregulation of transcription initiation from RNA polymerase II promoter FBgn0024509
GO:0007076
IEA
PLAZA Integrative Orthologymitotic chromosome condensation WBGene00003806
GO:0051656
IEA
PLAZA Integrative Orthologyestablishment of organelle localization ENSG00000157020
GO:0071407
IEA
PLAZA Integrative Orthologycellular response to organic cyclic compound FBgn0024509
GO:0032954
IEA
PLAZA Integrative Orthologyregulation of cytokinetic process WBGene00003806
GO:0033365
IEA
PLAZA Integrative Orthologyprotein localization to organelle WBGene00003806
GO:0000070
IEA
PLAZA Integrative Orthologymitotic sister chromatid segregation WBGene00003806
GO:0009719
IEA
PLAZA Integrative Orthologyresponse to endogenous stimulus FBgn0024509
GO:0006607
IEA
PLAZA Integrative OrthologyNLS-bearing protein import into nucleus FBgn0024509
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization WBGene00003806
GO:0006606
IEA
PLAZA Integrative Orthologyprotein import into nucleus WBGene00003806
GO:0051650
IEA
PLAZA Integrative Orthologyestablishment of vesicle localization ENSG00000157020
GO:0032955
IEA
PLAZA Integrative Orthologyregulation of division septum assembly WBGene00003806
GO:1990893
IEA
PLAZA Integrative Orthologymitotic chromosome centromere condensation WBGene00003806
GO:0042303
IEA
PLAZA Integrative Orthologymolting cycle FBgn0024509
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000157020
GO:0009725
IEA
PLAZA Integrative Orthologyresponse to hormone FBgn0024509
GO:0002495
IEA
PLAZA Integrative Orthologyantigen processing and presentation of peptide antigen via MHC class II ENSG00000157020
GO:0014070
IEA
PLAZA Integrative Orthologyresponse to organic cyclic compound FBgn0024509
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0024509
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process WBGene00003806
GO:0030261
IEA
PLAZA Integrative Orthologychromosome condensation WBGene00003806
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly ENSG00000157020
GO:0040003
IEA
PLAZA Integrative Orthologychitin-based cuticle development FBgn0024509
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization WBGene00003806
GO:0034504
IEA
PLAZA Integrative Orthologyprotein localization to nucleus WBGene00003806
GO:0019886
IEA
PLAZA Integrative Orthologyantigen processing and presentation of exogenous peptide antigen via MHC class II ENSG00000157020
GO:0019884
IEA
PLAZA Integrative Orthologyantigen processing and presentation of exogenous antigen ENSG00000157020
GO:0051648
IEA
PLAZA Integrative Orthologyvesicle localization ENSG00000157020
GO:0019882
IEA
PLAZA Integrative Orthologyantigen processing and presentation ENSG00000157020
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly ENSG00000157020
GO:0048002
IEA
PLAZA Integrative Orthologyantigen processing and presentation of peptide antigen ENSG00000157020
GO:0071495
IEA
PLAZA Integrative Orthologycellular response to endogenous stimulus FBgn0024509
GO:0051640
IEA
PLAZA Integrative Orthologyorganelle localization ENSG00000157020
GO:0002478
IEA
PLAZA Integrative Orthologyantigen processing and presentation of exogenous peptide antigen ENSG00000157020
GO:0006323
IEA
PLAZA Integrative OrthologyDNA packaging WBGene00003806
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process FBgn0024509
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process ENSG00000157020
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development FBgn0024509
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching WBGene00003806
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development WBGene00003806

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005198
IDA, IMP
Genome Projectstructural molecule activity
GO:0005198
IDA, IMP
Gene Ontologystructural molecule activity8 9 10
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000157020
GO:0003682
IEA
PLAZA Integrative Orthologychromatin binding FBgn0024509
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000157020
GO:0005488
IEA
PLAZA Integrative Orthologybinding ENSG00000157020

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0035859
IDA
Genome ProjectSeh1-associated complex
GO:0035859
IDA
Gene OntologySeh1-associated complex11
GO:0031080
IDA
Genome Projectnuclear pore outer ring
GO:0031080
IDA
Gene Ontologynuclear pore outer ring12 13
GO:0012507
IEA
Genome ProjectER to Golgi transport vesicle membrane
GO:0005634
IEA
Genome Projectnucleus
GO:0030127
IDA
Genome ProjectCOPII vesicle coat
GO:0030127
IDA
Gene OntologyCOPII vesicle coat14 15
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0005773
IEA
Genome Projectvacuole
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0005774
IEA
Genome Projectvacuolar membrane
GO:0005643
IEA
Genome Projectnuclear pore
GO:0071944
IDA
Genome Projectcell periphery
GO:0071944
Gene Ontologycell periphery16
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen AT2G30050
GO:0061700
IEA
PLAZA Integrative OrthologyGATOR2 complex ENSG00000157020
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part ENSG00000157020
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000157020
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000157020
GO:0000785
IEA
PLAZA Integrative Orthologychromatin FBgn0024509
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPBC215.15
GO:0005703
IEA
PLAZA Integrative Orthologypolytene chromosome puff FBgn0024509
GO:0005700
IEA
PLAZA Integrative Orthologypolytene chromosome FBgn0024509
GO:0000775
IEA
PLAZA Integrative Orthologychromosome, centromeric region ENSG00000157020
GO:0000776
IEA
PLAZA Integrative Orthologykinetochore ENSG00000157020
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000157020
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region ENSG00000157020
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000157020
GO:0000323
IEA
PLAZA Integrative Orthologylytic vacuole ENSG00000157020
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen AT2G30050
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000157020
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000157020
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus AT2G30050
GO:0005694
IEA
PLAZA Integrative Orthologychromosome ENSG00000157020
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen AT2G30050
GO:0005764
IEA
PLAZA Integrative Orthologylysosome ENSG00000157020
GO:0005765
IEA
PLAZA Integrative Orthologylysosomal membrane ENSG00000157020
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle AT2G30050
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen AT2G30050
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000157020
GO:0098852
IEA
PLAZA Integrative Orthologylytic vacuole membrane ENSG00000157020
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle AT2G30050

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001680WD40 repeat
IPR015943WD40/YVTN repeat-like-containing domain superfamily
IPR017986WD40-repeat-containing domain

No MapMan annotations defined for this gene.
KeggID Description
K14004SEC13; protein transport protein SEC13
No chloroplast target sequence found.