Gene: YKL032C (Saccharomyces cerevisiae strain S288C)

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Gene Identifier
YKL032C
Transcript Identifier
YKL032C
Gene Type
Coding gene
Location
XI : 380065-381858 : negative

Family Information

Homologous gene family
HOM02SEM000389
(90 genes in 26 species)
specific family

Descriptions

gene_descr
Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication

Identifiers

Type Value
pidYKL032C
UniprotP33417
RefSeq_mRNANM_001179598.1
EMBLBK006944
EMBLL16900
EMBLX71622
EMBLZ28032
SGDS000001515

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071456
IMP, IGI
Genome Projectcellular response to hypoxia
GO:0071456
IMP, IGI
Gene Ontologycellular response to hypoxia1
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0000122
IMP
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0000122
IMP
Gene Ontologynegative regulation of transcription by RNA polymerase II2
GO:0006281
IGI
Genome ProjectDNA repair
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change YMR072W
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YMR072W
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YMR072W
GO:0048311
IEA
PLAZA Integrative Orthologymitochondrion distribution YMR072W
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization YMR072W
GO:0051179
IEA
PLAZA Integrative Orthologylocalization YMR072W
GO:0000002
IEA
PLAZA Integrative Orthologymitochondrial genome maintenance YMR072W
GO:0048308
IEA
PLAZA Integrative Orthologyorganelle inheritance YMR072W
GO:0007005
IEA
PLAZA Integrative Orthologymitochondrion organization YMR072W
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization YMR072W
GO:0036385
IEA
PLAZA Integrative Orthologynucleoid DNA packaging YMR072W
GO:0051646
IEA
PLAZA Integrative Orthologymitochondrion localization YMR072W
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization YMR072W
GO:0051640
IEA
PLAZA Integrative Orthologyorganelle localization YMR072W
GO:0000001
IEA
PLAZA Integrative Orthologymitochondrion inheritance YMR072W
GO:0006323
IEA
PLAZA Integrative OrthologyDNA packaging YMR072W
GO:0090139
IEA
PLAZA Integrative Orthologymitochondrial DNA packaging YMR072W
GO:2000819
IGI
Gene Ontologyregulation of nucleotide-excision repair3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003684
IDA
Genome Projectdamaged DNA binding
GO:0003684
IDA
Gene Ontologydamaged DNA binding4
GO:0003677
IEA
Genome ProjectDNA binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0043565
IDA
Gene Ontologysequence-specific DNA binding1 2
GO:0008301
IEA
PLAZA Integrative OrthologyDNA binding, bending YMR072W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0000790
IDA
Gene Ontologynuclear chromatin1
GO:0005634
IEA
Genome Projectnucleus
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YMR072W
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm YMR072W
GO:0005759
IEA
PLAZA Integrative Orthologymitochondrial matrix YMR072W
GO:0042645
IEA
PLAZA Integrative Orthologymitochondrial nucleoid YMR072W
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part YMR072W
GO:0000229
IEA
PLAZA Integrative Orthologycytoplasmic chromosome YMR072W
GO:0044429
IEA
PLAZA Integrative Orthologymitochondrial part YMR072W
GO:0000262
IEA
PLAZA Integrative Orthologymitochondrial chromosome YMR072W
GO:0009295
IEA
PLAZA Integrative Orthologynucleoid YMR072W

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Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009071High mobility group box domain
IPR033311Intrastrand cross-link recognition protein/ARS-binding factor 2

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.