Gene: YGR163W (Saccharomyces cerevisiae strain S288C)

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Gene Identifier
YGR163W
Transcript Identifier
YGR163W
Gene Type
Coding gene
Location
VII : 827552-828577 : positive

Family Information

Homologous gene family
HOM02SEM002468
(28 genes in 22 species)
specific family
Orthologous gene family
ORTHO02SEM002764
(27 genes in 22 species)
specific family

Descriptions

gene_descr
Putative GTP binding protein; negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD

Identifiers

Type Value
pidYGR163W
UniprotP53290
RefSeq_mRNANM_001181292.1
EMBLAB015239
EMBLBK006941
EMBLZ72948
SGDS000003395

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0009267
IBA
Genome Projectcellular response to starvation
GO:0010507
IGI
Genome Projectnegative regulation of autophagy
GO:0010507
IGI
Gene Ontologynegative regulation of autophagy1
GO:0015031
IEA
Genome Projectprotein transport
GO:1903778
IMP
Genome Projectprotein localization to vacuolar membrane
GO:1903778
IMP
Gene Ontologyprotein localization to vacuolar membrane1
GO:0006914
IEA
Genome Projectautophagy
GO:0043547
IDA
Genome Projectpositive regulation of GTPase activity
GO:0043547
IDA
Gene Ontologypositive regulation of GTPase activity2
GO:1904263
IMP, IGI
Genome Projectpositive regulation of TORC1 signaling
GO:1904263
IMP, IGI
Gene Ontologypositive regulation of TORC1 signaling3 4
GO:0045944
IDA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IDA
Gene Ontologypositive regulation of transcription by RNA polymerase II5
GO:0016237
IMP
Genome Projectlysosomal microautophagy
GO:0016237
IMP
Gene Ontologylysosomal microautophagy6
GO:0071230
IBA
Genome Projectcellular response to amino acid stimulus
GO:2000785
IEA
PLAZA Integrative Orthologyregulation of autophagosome assembly WBGene00012497
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication SPCC777.05
GO:0006995
IEA
PLAZA Integrative Orthologycellular response to nitrogen starvation SPCC777.05
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle ENSG00000116954
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization WBGene00012497
GO:0007568
IEA
PLAZA Integrative Orthologyaging WBGene00012497
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00012497
GO:0016236
IEA
PLAZA Integrative Orthologymacroautophagy ENSG00000116954
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00012497
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus SPCC777.05
GO:0071233
IEA
PLAZA Integrative Orthologycellular response to leucine ENSG00000025039
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction SPCC777.05
GO:0000045
IEA
PLAZA Integrative Orthologyautophagosome assembly WBGene00012497
GO:0043201
IEA
PLAZA Integrative Orthologyresponse to leucine ENSG00000025039
GO:1902532
IEA
PLAZA Integrative Orthologynegative regulation of intracellular signal transduction SPCC777.05
GO:0043562
IEA
PLAZA Integrative Orthologycellular response to nitrogen levels SPCC777.05
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development WBGene00012497
GO:0045786
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle ENSG00000116954
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization WBGene00012497
GO:0007033
IEA
PLAZA Integrative Orthologyvacuole organization WBGene00012497
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development WBGene00012497
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis WBGene00012497
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization WBGene00012497
GO:0016241
IEA
PLAZA Integrative Orthologyregulation of macroautophagy ENSG00000116954
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling SPCC777.05
GO:1905037
IEA
PLAZA Integrative Orthologyautophagosome organization WBGene00012497
GO:0007264
IEA
PLAZA Integrative Orthologysmall GTPase mediated signal transduction ENSG00000116954
GO:1904262
IEA
PLAZA Integrative Orthologynegative regulation of TORC1 signaling SPCC777.05
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization WBGene00012497
GO:1990928
IEA
PLAZA Integrative Orthologyresponse to amino acid starvation ENSG00000116954
GO:0032007
IEA
PLAZA Integrative Orthologynegative regulation of TOR signaling SPCC777.05
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle ENSG00000116954
GO:0010259
IEA
PLAZA Integrative Orthologymulticellular organism aging WBGene00012497
GO:0044088
IEA
PLAZA Integrative Orthologyregulation of vacuole organization WBGene00012497
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis WBGene00012497
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis WBGene00012497
GO:1990253
IEA
PLAZA Integrative Orthologycellular response to leucine starvation ENSG00000025039
GO:1902115
IEA
PLAZA Integrative Orthologyregulation of organelle assembly WBGene00012497
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process ENSG00000116954
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly WBGene00012497
GO:0008340
IEA
PLAZA Integrative Orthologydetermination of adult lifespan WBGene00012497
GO:0034198
IEA
PLAZA Integrative Orthologycellular response to amino acid starvation ENSG00000116954
GO:0070925
IEA
PLAZA Integrative Orthologyorganelle assembly WBGene00012497
GO:0007050
IEA
PLAZA Integrative Orthologycell cycle arrest ENSG00000116954

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005525
IDA
IEA
Genome ProjectGTP binding
GO:0005525
IDA
Gene OntologyGTP binding7
GO:0003924
IDA
Genome ProjectGTPase activity
GO:0003924
IDA
Gene OntologyGTPase activity4
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000116954
GO:0051020
IEA
PLAZA Integrative OrthologyGTPase binding ENSG00000116954
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000116954
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000116954
GO:0019003
IEA
PLAZA Integrative OrthologyGDP binding ENSG00000116954
GO:0046982
IEA
PLAZA Integrative Orthologyprotein heterodimerization activity ENSG00000116954

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990131
IPI
Genome ProjectGtr1-Gtr2 GTPase complex
GO:1990131
IPI
Gene OntologyGtr1-Gtr2 GTPase complex7 8
GO:0016020
IEA
Genome Projectmembrane
GO:0005764
IBA
Genome Projectlysosome
GO:0005773
IEA
Genome Projectvacuole
GO:0034448
IDA, IPI
Genome ProjectEGO complex
GO:0034448
IDA, IPI
Gene OntologyEGO complex6 9
GO:0005774
IEA
Genome Projectvacuolar membrane
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm8 10
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus8 10
GO:0016021
ISM
Genome Projectintegral component of membrane
GO:0016021
ISM
Gene Ontologyintegral component of membrane11
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0000790
IDA
Gene Ontologynuclear chromatin5
GO:0000329
IDA
Genome Projectfungal-type vacuole membrane
GO:0000329
IDA
Gene Ontologyfungal-type vacuole membrane6 12
GO:0031902
IDA
Genome Projectlate endosome membrane
GO:0031902
IDA
Gene Ontologylate endosome membrane9
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part ENSG00000025039
GO:0005815
IEA
PLAZA Integrative Orthologymicrotubule organizing center ENSG00000025039
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton ENSG00000025039
GO:0005813
IEA
PLAZA Integrative Orthologycentrosome ENSG00000025039
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000025039
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPCC777.05
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton ENSG00000025039

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006762Gtr1/RagA G protein
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K16186RRAGC_D; Ras-related GTP-binding protein C/D
No chloroplast target sequence found.