Gene: YGL169W (Saccharomyces cerevisiae strain S288C)

Overview top

Gene Identifier
YGL169W
Transcript Identifier
YGL169W
Gene Type
Coding gene
Location
VII : 186059-187339 : positive

Family Information

Homologous gene family
HOM02SEM001790
(34 genes in 25 species)
specific family
Orthologous gene family
ORTHO02SEM001890
(34 genes in 25 species)
specific family

Descriptions

gene_descr
Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; null mutant lacks N6- threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family; binds single-stranded telomeric DNA and null mutant has abnormal telomere length

Identifiers

Type Value
pidYGL169W
UniprotP32579
RefSeq_mRNANM_001181034.1
EMBLBK006941
EMBLX64319
EMBLX85757
EMBLZ72691
SGDS000003137

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006417
IEA
Genome Projectregulation of translation
GO:0006450
IMP
Genome Projectregulation of translational fidelity
GO:0006450
IMP
Gene Ontologyregulation of translational fidelity1
GO:0000723
IMP
Genome Projecttelomere maintenance
GO:0000723
IMP
Gene Ontologytelomere maintenance2
GO:0070525
IMP
Genome ProjecttRNA threonylcarbamoyladenosine metabolic process
GO:0070525
IMP
Gene OntologytRNA threonylcarbamoyladenosine metabolic process3 4
GO:0002949
IDA
Genome ProjecttRNA threonylcarbamoyladenosine modification
GO:0002949
IDA
Gene OntologytRNA threonylcarbamoyladenosine modification5
GO:0008033
IEA
Genome ProjecttRNA processing
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000196449
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process ENSG00000196449
GO:0051051
IEA
PLAZA Integrative Orthologynegative regulation of transport ENSG00000196449
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000196449
GO:0051179
IEA
PLAZA Integrative Orthologylocalization ENSG00000196449
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization ENSG00000196449
GO:0051049
IEA
PLAZA Integrative Orthologyregulation of transport ENSG00000196449

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
Genome ProjectATP binding
GO:0003725
IEA
Genome Projectdouble-stranded RNA binding
GO:0043047
IDA
Genome Projectsingle-stranded telomeric DNA binding
GO:0043047
IDA
Gene Ontologysingle-stranded telomeric DNA binding2
GO:0016779
IBA
IEA
Genome Projectnucleotidyltransferase activity
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0061710
IEA
Genome ProjectL-threonylcarbamoyladenylate synthase
GO:0000049
IBA
Genome ProjecttRNA binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0061711
IDA
Gene OntologyN(6)-L-threonylcarbamoyladenine synthase activity5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000781
IEA
Genome Projectchromosome, telomeric region
GO:0005634
IEA
Genome Projectnucleus
GO:0005694
IEA
Genome Projectchromosome
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005737
Gene Ontologycytoplasm6
GO:0005829
IDA
Genome Projectcytosol
GO:0005829
Gene Ontologycytosol7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005145Putative GTP-binding controlling metal-binding domain
IPR006070YrdC-like domain
IPR010923tRNA threonylcarbamoyladenosine biosynthesis protein SUA5
IPR017945DHBP synthase RibB-like alpha/beta domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K07566tsaC, rimN, SUA5; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
No chloroplast target sequence found.