Gene: YER151C (Saccharomyces cerevisiae strain S288C)

Overview top

Gene Identifier
YER151C
Transcript Identifier
YER151C
Gene Type
Coding gene
Location
V : 469686-472424 : negative

Family Information

Homologous gene family
HOM02SEM000130
(193 genes in 26 species)
specific family

Descriptions

gene_descr
Ubiquitin-specific protease involved in transport and osmotic response; interacts with Bre5p to co-regulate anterograde and retrograde transport between the ER and Golgi; involved in transcription elongation in response to osmostress through phosphorylation at Ser695 by Hog1p; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin; also has mRNA binding activity; protein abundance increases in response to DNA replication stress; role in ribophagy

Identifiers

Type Value
pidYER151C
UniprotQ01477
RefSeq_mRNANM_001179041.1
EMBLBK006939
EMBLM94917
EMBLU18917
SGDS000000953

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0047484
IPI, IMP
Genome Projectregulation of response to osmotic stress
GO:0047484
IPI, IMP
Gene Ontologyregulation of response to osmotic stress1
GO:0016579
IDA, IMP
IEA
Genome Projectprotein deubiquitination
GO:0016579
IDA, IMP
Gene Ontologyprotein deubiquitination2 3 4
GO:0034517
IMP
Genome Projectribophagy
GO:0034517
IMP
Gene Ontologyribophagy5
GO:0006511
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006508
IEA
Genome Projectproteolysis
GO:0060628
IMP
Genome Projectregulation of ER to Golgi vesicle-mediated transport
GO:0060628
IMP
Gene Ontologyregulation of ER to Golgi vesicle-mediated transport6
GO:0035967
IEA
PLAZA Integrative Orthologycellular response to topologically incorrect protein SPBP8B7.21
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000103194
GO:0071347
IEA
PLAZA Integrative Orthologycellular response to interleukin-1 ENSG00000103194
GO:0035966
IEA
PLAZA Integrative Orthologyresponse to topologically incorrect protein SPBP8B7.21
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000103194
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process ENSG00000103194
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0052479
GO:0071629
IEA
PLAZA Integrative Orthologycytoplasm protein quality control by the ubiquitin-proteasome system SPBP8B7.21
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction ENSG00000103194
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process ENSG00000103194
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process ENSG00000103194
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress SPBP8B7.21
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus ENSG00000103194
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction ENSG00000103194
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0052479
GO:0045747
IEA
PLAZA Integrative Orthologypositive regulation of Notch signaling pathway FBgn0052479
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process ENSG00000103194
GO:1902532
IEA
PLAZA Integrative Orthologynegative regulation of intracellular signal transduction ENSG00000103194
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process ENSG00000103194
GO:0007154
IEA
PLAZA Integrative Orthologycell communication ENSG00000103194
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000103194
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000103194
GO:0034097
IEA
PLAZA Integrative Orthologyresponse to cytokine ENSG00000103194
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000103194
GO:0010506
IEA
PLAZA Integrative Orthologyregulation of autophagy ENSG00000103194
GO:0030330
IEA
PLAZA Integrative OrthologyDNA damage response, signal transduction by p53 class mediator ENSG00000103194
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway FBgn0052479
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process ENSG00000103194
GO:0043161
IEA
PLAZA Integrative Orthologyproteasome-mediated ubiquitin-dependent protein catabolic process SPBP8B7.21
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process ENSG00000103194
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical SPBP8B7.21
GO:0006259
IEA
PLAZA Integrative OrthologyDNA metabolic process ENSG00000103194
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process ENSG00000103194
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus SPBP8B7.21
GO:0071218
IEA
PLAZA Integrative Orthologycellular response to misfolded protein SPBP8B7.21
GO:0006515
IEA
PLAZA Integrative Orthologyprotein quality control for misfolded or incompletely synthesized proteins SPBP8B7.21
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process ENSG00000103194
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000103194
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus SPBP8B7.21
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0052479
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication ENSG00000103194
GO:0031329
IEA
PLAZA Integrative Orthologyregulation of cellular catabolic process ENSG00000103194
GO:0007249
IEA
PLAZA Integrative OrthologyI-kappaB kinase/NF-kappaB signaling ENSG00000103194
GO:0051788
IEA
PLAZA Integrative Orthologyresponse to misfolded protein SPBP8B7.21
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis ENSG00000103194
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process ENSG00000103194
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000103194
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance SPBP8B7.21
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process ENSG00000103194
GO:0006301
IEA
PLAZA Integrative Orthologypostreplication repair ENSG00000103194
GO:0009894
IEA
PLAZA Integrative Orthologyregulation of catabolic process ENSG00000103194
GO:0043124
IEA
PLAZA Integrative Orthologynegative regulation of I-kappaB kinase/NF-kappaB signaling ENSG00000103194
GO:0043122
IEA
PLAZA Integrative Orthologyregulation of I-kappaB kinase/NF-kappaB signaling ENSG00000103194
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000103194
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process ENSG00000103194
GO:0070555
IEA
PLAZA Integrative Orthologyresponse to interleukin-1 ENSG00000103194
GO:0072331
IEA
PLAZA Integrative Orthologysignal transduction by p53 class mediator ENSG00000103194
GO:0023052
IEA
PLAZA Integrative Orthologysignaling ENSG00000103194
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0052479
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000103194
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling ENSG00000103194
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process ENSG00000103194
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000103194
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0052479
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus ENSG00000103194
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process ENSG00000103194
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway FBgn0052479
GO:0010498
IEA
PLAZA Integrative Orthologyproteasomal protein catabolic process SPBP8B7.21
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance SPBP8B7.21
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction ENSG00000103194
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process ENSG00000103194
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0052479
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process FBgn0052479
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process ENSG00000103194
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair ENSG00000103194
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair ENSG00000103194
GO:0042770
IEA
PLAZA Integrative Orthologysignal transduction in response to DNA damage ENSG00000103194

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0004843
IDA, IMP
Genome Projectthiol-dependent ubiquitin-specific protease activity
GO:0004843
IDA, IMP
Gene Ontologythiol-dependent ubiquitin-specific protease activity3 7
GO:0036459
IEA
Genome Projectthiol-dependent ubiquitinyl hydrolase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0003729
IDA
Genome ProjectmRNA binding
GO:0003729
IDA
Gene OntologymRNA binding8 9
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0004175
IEA
PLAZA Integrative Orthologyendopeptidase activity ENSG00000103194
GO:1905538
IEA
PLAZA Integrative Orthologypolysome binding SPBP8B7.21
GO:0004197
IEA
PLAZA Integrative Orthologycysteine-type endopeptidase activity ENSG00000103194
GO:0002039
IEA
PLAZA Integrative Orthologyp53 binding ENSG00000103194
GO:0044877
IEA
PLAZA Integrative Orthologyprotein-containing complex binding SPBP8B7.21
GO:0043021
IEA
PLAZA Integrative Orthologyribonucleoprotein complex binding SPBP8B7.21
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000103194
GO:0044325
IEA
PLAZA Integrative Orthologyion channel binding ENSG00000103194

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990861
IPI
Genome ProjectUbp3-Bre5 deubiquitination complex
GO:1990861
IPI
Gene OntologyUbp3-Bre5 deubiquitination complex6
GO:0005829
IDA
Genome Projectcytosol
GO:0005829
Gene Ontologycytosol10
GO:0005737
IDA
IC
Genome Projectcytoplasm
GO:0005737
IDA
IC
Gene Ontologycytoplasm7 9
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system ENSG00000103194
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000103194
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part ENSG00000103194
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000103194
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle ENSG00000103194
GO:1990904
IEA
PLAZA Integrative Orthologyribonucleoprotein complex SPBP8B7.21
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle ENSG00000103194
GO:0005768
IEA
PLAZA Integrative Orthologyendosome ENSG00000103194
GO:0005769
IEA
PLAZA Integrative Orthologyearly endosome ENSG00000103194
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000103194
GO:0036464
IEA
PLAZA Integrative Orthologycytoplasmic ribonucleoprotein granule SPBP8B7.21
GO:0010494
IEA
PLAZA Integrative Orthologycytoplasmic stress granule SPBP8B7.21
GO:0035770
IEA
PLAZA Integrative Orthologyribonucleoprotein granule SPBP8B7.21
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000103194
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000103194
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000103194
GO:0005634
IEA
PLAZA Integrative Orthologynucleus SPBP8B7.21
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part ENSG00000103194
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000103194
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPBP8B7.21
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle SPBP8B7.21
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPBP8B7.21
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle SPBP8B7.21
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle SPBP8B7.21
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle SPBP8B7.21

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001394Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR018200Ubiquitin specific protease, conserved site
IPR028889Ubiquitin specific protease domain

No MapMan annotations defined for this gene.
KeggID Description
K11841USP10, UBP3; ubiquitin carboxyl-terminal hydrolase 10
No chloroplast target sequence found.