Gene: YDR410C (Saccharomyces cerevisiae strain S288C)

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Gene Identifier
YDR410C
Transcript Identifier
YDR410C
Gene Type
Coding gene
Location
IV : 1292372-1293091 : negative

Family Information

Homologous gene family
HOM02SEM002401
(29 genes in 21 species)
specific family
Orthologous gene family
ORTHO02SEM002773
(27 genes in 21 species)
specific family

Descriptions

gene_descr
Farnesyl cysteine-carboxyl methyltransferase; mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane

Identifiers

Type Value
pidYDR410C
UniprotP32584
RefSeq_mRNANM_001180718.1
EMBLBK006938
EMBLL07952
EMBLL15442
EMBLU33007
SGDS000002818

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006481
IMP
IEA
Genome ProjectC-terminal protein methylation
GO:0006481
IMP
Gene OntologyC-terminal protein methylation1
GO:0019236
IEA
Genome Projectresponse to pheromone
GO:0007323
IMP
Genome Projectpeptide pheromone maturation
GO:0007323
IMP
Gene Ontologypeptide pheromone maturation2
GO:0032259
IEA
Genome Projectmethylation
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport ENSG00000116237
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process SPAC10F6.12c
GO:0018125
IEA
PLAZA Integrative Orthologypeptidyl-cysteine methylation SPAC10F6.12c
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus SPAC10F6.12c
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000116237
GO:0042886
IEA
PLAZA Integrative Orthologyamide transport ENSG00000116237
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction SPAC10F6.12c
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process SPAC10F6.12c
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT5G08335
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport ENSG00000116237
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process SPAC10F6.12c
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT5G08335
GO:0031137
IEA
PLAZA Integrative Orthologyregulation of conjugation with cellular fusion SPAC10F6.12c
GO:0031136
IEA
PLAZA Integrative Orthologypositive regulation of conjugation SPAC10F6.12c
GO:0031139
IEA
PLAZA Integrative Orthologypositive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0140253
IEA
PLAZA Integrative Orthologycell-cell fusion SPAC10F6.12c
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT5G08335
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process SPAC10F6.12c
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization SPAC10F6.12c
GO:0071432
IEA
PLAZA Integrative Orthologypeptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion SPAC10F6.12c
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance SPAC10F6.12c
GO:0046999
IEA
PLAZA Integrative Orthologyregulation of conjugation SPAC10F6.12c
GO:0090150
IEA
PLAZA Integrative Orthologyestablishment of protein localization to membrane ENSG00000116237
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT5G08335
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT5G08335
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization SPAC10F6.12c
GO:0015833
IEA
PLAZA Integrative Orthologypeptide transport ENSG00000116237
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction SPAC10F6.12c
GO:0071444
IEA
PLAZA Integrative Orthologycellular response to pheromone SPAC10F6.12c
GO:2000243
IEA
PLAZA Integrative Orthologypositive regulation of reproductive process SPAC10F6.12c
GO:0072657
IEA
PLAZA Integrative Orthologyprotein localization to membrane ENSG00000116237
GO:0048731
IEA
PLAZA Integrative Orthologysystem development AT5G08335
GO:0051179
IEA
PLAZA Integrative Orthologylocalization SPAC10F6.12c
GO:0006605
IEA
PLAZA Integrative Orthologyprotein targeting ENSG00000116237
GO:0045184
IEA
PLAZA Integrative Orthologyestablishment of protein localization ENSG00000116237
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000116237
GO:0006612
IEA
PLAZA Integrative Orthologyprotein targeting to membrane ENSG00000116237
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process SPAC10F6.12c
GO:0000746
IEA
PLAZA Integrative Orthologyconjugation SPAC10F6.12c
GO:0000747
IEA
PLAZA Integrative Orthologyconjugation with cellular fusion SPAC10F6.12c
GO:0046907
IEA
PLAZA Integrative Orthologyintracellular transport ENSG00000116237
GO:0000749
IEA
PLAZA Integrative Orthologyresponse to pheromone triggering conjugation with cellular fusion SPAC10F6.12c
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT5G08335
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation SPAC10F6.12c
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus SPAC10F6.12c
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell ENSG00000116237
GO:0018351
IEA
PLAZA Integrative Orthologypeptidyl-cysteine esterification SPAC10F6.12c
GO:0018198
IEA
PLAZA Integrative Orthologypeptidyl-cysteine modification SPAC10F6.12c
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT5G08335
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT5G08335
GO:0018350
IEA
PLAZA Integrative Orthologyprotein esterification SPAC10F6.12c
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process SPAC10F6.12c
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification SPAC10F6.12c
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization SPAC10F6.12c
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process SPAC10F6.12c
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT5G08335
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT5G08335
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process SPAC10F6.12c
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport ENSG00000116237
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization SPAC10F6.12c
GO:0015031
IEA
PLAZA Integrative Orthologyprotein transport ENSG00000116237
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT5G08335
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process SPAC10F6.12c
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization SPAC10F6.12c
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process SPAC10F6.12c
GO:0018229
IEA
PLAZA Integrative Orthologypeptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine SPAC10F6.12c
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process SPAC10F6.12c

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004671
IDA, IMP
IEA
Genome Projectprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0004671
IDA, IMP
Gene Ontologyprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity2 3 4
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005783
Gene Ontologyendoplasmic reticulum5
GO:0016021
ISM
IEA
Genome Projectintegral component of membrane
GO:0016021
ISM
Gene Ontologyintegral component of membrane6
GO:0016020
IEA
Genome Projectmembrane
GO:0005789
IDA
Genome Projectendoplasmic reticulum membrane
GO:0005789
IDA
Gene Ontologyendoplasmic reticulum membrane4 7
GO:0005637
IMP
Genome Projectnuclear inner membrane
GO:0005637
IMP
Gene Ontologynuclear inner membrane8

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR007269Isoprenylcysteine carboxyl methyltransferase
IPR025770Protein-S-isoprenylcysteine O-methyltransferase

No MapMan annotations defined for this gene.
KeggID Description
K00587ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100]
No chloroplast target sequence found.