Gene: YDR224C (Saccharomyces cerevisiae strain S288C)

Overview top

Gene Identifier
YDR224C
Transcript Identifier
YDR224C
Gene Type
Coding gene
Location
IV : 914317-914712 : negative

Family Information

Homologous gene family
HOM02SEM000115
(203 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000104
(198 genes in 26 species)
specific family

Descriptions

gene_descr
Histone H2B; core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB2; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates reassembly after DNA replication, transcriptional activation, meiotic DSB formation and H3 methylation

Identifiers

Type Value
pidYDR224C
UniprotP02293
RefSeq_mRNANM_001180532.1
EMBLAY557724
EMBLBK006938
EMBLJ01327
EMBLM37743
EMBLU13239
EMBLZ48612
SGDS000002632

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006333
IDA
Genome Projectchromatin assembly or disassembly
GO:0006333
IDA
Gene Ontologychromatin assembly or disassembly1 2
GO:0006301
IGI
Genome Projectpostreplication repair
GO:0006301
IGI
Gene Ontologypostreplication repair3
GO:0000122
IMP
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0000122
IMP
Gene Ontologynegative regulation of transcription by RNA polymerase II4
GO:0006334
IBA
Genome Projectnucleosome assembly
GO:0060761
IEA
PLAZA Integrative Orthologynegative regulation of response to cytokine stimulus ENSG00000124635
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development ENSG00000234289
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000180596
GO:0006959
IEA
PLAZA Integrative Orthologyhumoral immune response ENSG00000180596
GO:0050830
IEA
PLAZA Integrative Orthologydefense response to Gram-positive bacterium ENSG00000180596
GO:0032446
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation ENSG00000276410
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance ENSG00000124635
GO:0002251
IEA
PLAZA Integrative Orthologyorgan or tissue specific immune response ENSG00000180596
GO:0007420
IEA
PLAZA Integrative Orthologybrain development ENSG00000234289
GO:0060759
IEA
PLAZA Integrative Orthologyregulation of response to cytokine stimulus ENSG00000124635
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000124635
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000180596
GO:0061844
IEA
PLAZA Integrative Orthologyantimicrobial humoral immune response mediated by antimicrobial peptide ENSG00000180596
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling ENSG00000124635
GO:0007417
IEA
PLAZA Integrative Orthologycentral nervous system development ENSG00000234289
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000124635
GO:0023052
IEA
PLAZA Integrative Orthologysignaling ENSG00000124635
GO:0001959
IEA
PLAZA Integrative Orthologyregulation of cytokine-mediated signaling pathway ENSG00000124635
GO:0034612
IEA
PLAZA Integrative Orthologyresponse to tumor necrosis factor ENSG00000124635
GO:0035821
IEA
PLAZA Integrative Orthologymodification of morphology or physiology of other organism ENSG00000124635
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism ENSG00000180596
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance ENSG00000124635
GO:0019221
IEA
PLAZA Integrative Orthologycytokine-mediated signaling pathway ENSG00000124635
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process ENSG00000180596
GO:0006952
IEA
PLAZA Integrative Orthologydefense response ENSG00000180596
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification ENSG00000276410
GO:0021762
IEA
PLAZA Integrative Orthologysubstantia nigra development ENSG00000234289
GO:0002227
IEA
PLAZA Integrative Orthologyinnate immune response in mucosa ENSG00000180596
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication ENSG00000124635
GO:0010804
IEA
PLAZA Integrative Orthologynegative regulation of tumor necrosis factor-mediated signaling pathway ENSG00000124635
GO:0010803
IEA
PLAZA Integrative Orthologyregulation of tumor necrosis factor-mediated signaling pathway ENSG00000124635
GO:0019731
IEA
PLAZA Integrative Orthologyantibacterial humoral response ENSG00000180596
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000124635
GO:0019730
IEA
PLAZA Integrative Orthologyantimicrobial humoral response ENSG00000180596
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process ENSG00000276410
GO:0060322
IEA
PLAZA Integrative Orthologyhead development ENSG00000234289
GO:0030901
IEA
PLAZA Integrative Orthologymidbrain development ENSG00000234289
GO:0044364
IEA
PLAZA Integrative Orthologydisruption of cells of other organism ENSG00000124635
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal ENSG00000276410
GO:0001906
IEA
PLAZA Integrative Orthologycell killing ENSG00000124635
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus ENSG00000124635
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical ENSG00000124635
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium ENSG00000180596
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism ENSG00000180596
GO:0033209
IEA
PLAZA Integrative Orthologytumor necrosis factor-mediated signaling pathway ENSG00000124635
GO:0048731
IEA
PLAZA Integrative Orthologysystem development ENSG00000234289
GO:0016567
IEA
PLAZA Integrative Orthologyprotein ubiquitination ENSG00000276410
GO:0034097
IEA
PLAZA Integrative Orthologyresponse to cytokine ENSG00000124635
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process ENSG00000276410
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus ENSG00000180596
GO:0044419
IEA
PLAZA Integrative Orthologyinterspecies interaction between organisms ENSG00000124635
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development ENSG00000234289
GO:0007154
IEA
PLAZA Integrative Orthologycell communication ENSG00000124635
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process ENSG00000276410
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development ENSG00000234289
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development ENSG00000234289
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process ENSG00000276410
GO:0002385
IEA
PLAZA Integrative Orthologymucosal immune response ENSG00000180596
GO:0048857
IEA
PLAZA Integrative Orthologyneural nucleus development ENSG00000234289
GO:0001960
IEA
PLAZA Integrative Orthologynegative regulation of cytokine-mediated signaling pathway ENSG00000124635
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus ENSG00000180596
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000124635
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus ENSG00000180596
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction ENSG00000124635
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus ENSG00000124635
GO:0071356
IEA
PLAZA Integrative Orthologycellular response to tumor necrosis factor ENSG00000124635
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process ENSG00000234289
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process ENSG00000234289
GO:0050829
IEA
PLAZA Integrative Orthologydefense response to Gram-negative bacterium ENSG00000124635
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction ENSG00000124635
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process ENSG00000276410
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway ENSG00000124635
GO:0009617
IEA
PLAZA Integrative Orthologyresponse to bacterium ENSG00000180596
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response ENSG00000180596
GO:0031640
IEA
PLAZA Integrative Orthologykilling of cells of other organism ENSG00000124635
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000124635

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003677
IDA
Gene OntologyDNA binding1
GO:0097367
IEA
PLAZA Integrative Orthologycarbohydrate derivative binding ENSG00000124635
GO:0008289
IEA
PLAZA Integrative Orthologylipid binding ENSG00000124635
GO:0001530
IEA
PLAZA Integrative Orthologylipopolysaccharide binding ENSG00000124635
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000180596
GO:0044389
IEA
PLAZA Integrative Orthologyubiquitin-like protein ligase binding ENSG00000275713
GO:0097677
IEA
PLAZA Integrative OrthologySTAT family protein binding ENSG00000275713
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000275713

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031298
IDA
Genome Projectreplication fork protection complex
GO:0031298
IDA
Gene Ontologyreplication fork protection complex5
GO:0005694
IEA
Genome Projectchromosome
GO:0000786
IEA
Genome Projectnucleosome
GO:0005634
IEA
Genome Projectnucleus
GO:0000788
IDA
Genome Projectnuclear nucleosome
GO:0000788
IDA
Gene Ontologynuclear nucleosome2
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPCC622.09
GO:0044434
IEA
PLAZA Integrative Orthologychloroplast part AT3G45980
GO:0044435
IEA
PLAZA Integrative Orthologyplastid part AT3G45980
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000180596
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part AT3G45980
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane ENSG00000124635
GO:0005911
IEA
PLAZA Integrative Orthologycell-cell junction AT3G46030
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000180596
GO:0031984
IEA
PLAZA Integrative Orthologyorganelle subcompartment AT3G45980
GO:0009534
IEA
PLAZA Integrative Orthologychloroplast thylakoid AT3G45980
GO:0009532
IEA
PLAZA Integrative Orthologyplastid stroma AT3G45980
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus AT5G02570
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000180596
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT3G45980
GO:0031976
IEA
PLAZA Integrative Orthologyplastid thylakoid AT3G45980
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000180596
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000180596
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm AT3G45980
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region ENSG00000276410
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery ENSG00000124635
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000180596
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region ENSG00000276410
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT3G45980
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT3G46030
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000276410
GO:0000784
IEA
PLAZA Integrative Orthologynuclear chromosome, telomeric region ENSG00000276410
GO:0030054
IEA
PLAZA Integrative Orthologycell junction AT3G46030
GO:0009570
IEA
PLAZA Integrative Orthologychloroplast stroma AT3G45980
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPCC622.09
GO:0009579
IEA
PLAZA Integrative Orthologythylakoid AT3G45980
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000276410
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT3G46030
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000180596
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000124635

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000558Histone H2B
IPR007125Histone H2A/H2B/H3
IPR009072Histone-fold

No MapMan annotations defined for this gene.
KeggID Description
K11252H2B; histone H2B
No chloroplast target sequence found.