Gene: WBGene00000275 (Caenorhabditis elegans)

Overview top

Gene Identifier
WBGene00000275
Transcript Identifier
R06C7.8
Gene Type
Coding gene
Location
I : 7251947-7255131 : positive

Family Information

Homologous gene family
HOM02SEM015392
(5 genes in 1 species)
specific family

Descriptions

gene_descr
Caenorhabditis elegans Protein BUB-1 (bub-1) mRNA, complete cds.

Identifiers

Type Value
pidR06C7.8
UniprotQ21776
RefSeq_mRNANM_059650.4
EMBLZ71266

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0040035
IEA
Genome Projecthermaphrodite genitalia development
GO:0040011
IEA
Genome Projectlocomotion
GO:0009792
IEA
Genome Projectembryo development ending in birth or egg hatching
GO:0008406
IMP
IEA
Genome Projectgonad development
GO:0008406
IMP
Gene Ontologygonad development1
GO:0006915
IEA
Genome Projectapoptotic process
GO:0002119
IEA
Genome Projectnematode larval development
GO:0000003
IEA
Genome Projectreproduction
GO:1905342
IMP
Genome Projectpositive regulation of protein localization to kinetochore
GO:1905342
IMP
Gene Ontologypositive regulation of protein localization to kinetochore2
GO:1903394
IMP
Genome Projectprotein localization to kinetochore involved in kinetochore assembly
GO:1903394
IMP
Gene Ontologyprotein localization to kinetochore involved in kinetochore assembly2
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0051316
IMP
Genome Projectattachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation
GO:0051316
IMP
Gene Ontologyattachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation3
GO:0051307
IMP
Genome Projectmeiotic chromosome separation
GO:0051307
IMP
Gene Ontologymeiotic chromosome separation3 4
GO:0051301
IMP
IEA
Genome Projectcell division
GO:0051301
IMP
Gene Ontologycell division1
GO:0051257
IMP
Genome Projectmeiotic spindle midzone assembly
GO:0051257
IMP
Gene Ontologymeiotic spindle midzone assembly3
GO:0048666
IMP
Genome Projectneuron development
GO:0048666
IMP
Gene Ontologyneuron development1
GO:0048598
IMP
Genome Projectembryonic morphogenesis
GO:0048598
IMP
Gene Ontologyembryonic morphogenesis1
GO:0034501
IMP
Genome Projectprotein localization to kinetochore
GO:0034501
IMP
Gene Ontologyprotein localization to kinetochore4
GO:0016310
IEA
Genome Projectphosphorylation
GO:0007275
IEA
Genome Projectmulticellular organism development
GO:0007094
IEA
Genome Projectmitotic spindle assembly checkpoint
GO:0007049
IEA
Genome Projectcell cycle
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0000280
IMP
Genome Projectnuclear division
GO:0000280
IMP
Gene Ontologynuclear division1
GO:0000212
IMP
Genome Projectmeiotic spindle organization
GO:0000212
IMP
Gene Ontologymeiotic spindle organization3
GO:0051754
IEA
PLAZA Integrative Orthologymeiotic sister chromatid cohesion, centromeric SPCC1322.12c
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process FBgn0263855
GO:0006508
IEA
PLAZA Integrative Orthologyproteolysis ENSG00000156970
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process FBgn0263855
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization SPCC1322.12c
GO:0072395
IEA
PLAZA Integrative Orthologysignal transduction involved in cell cycle checkpoint SPCC1322.12c
GO:0048232
IEA
PLAZA Integrative Orthologymale gamete generation FBgn0263855
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0263855
GO:0006511
IEA
PLAZA Integrative Orthologyubiquitin-dependent protein catabolic process ENSG00000156970
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated FBgn0263855
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process ENSG00000156970
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process FBgn0263855
GO:0030163
IEA
PLAZA Integrative Orthologyprotein catabolic process ENSG00000156970
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated FBgn0263855
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction SPCC1322.12c
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0263855
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process FBgn0263855
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus SPCC1322.12c
GO:0019941
IEA
PLAZA Integrative Orthologymodification-dependent protein catabolic process ENSG00000156970
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription FBgn0263855
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process FBgn0263855
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process FBgn0263855
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription FBgn0263855
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process FBgn0263855
GO:0031134
IEA
PLAZA Integrative Orthologysister chromatid biorientation YGR188C
GO:0031937
IEA
PLAZA Integrative Orthologypositive regulation of chromatin silencing FBgn0263855
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process ENSG00000156970
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0263855
GO:0031935
IEA
PLAZA Integrative Orthologyregulation of chromatin silencing FBgn0263855
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription FBgn0263855
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription FBgn0263855
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process FBgn0263855
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing FBgn0263855
GO:0044257
IEA
PLAZA Integrative Orthologycellular protein catabolic process ENSG00000156970
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process FBgn0263855
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0263855
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process ENSG00000156970
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process YGR188C
GO:0007154
IEA
PLAZA Integrative Orthologycell communication SPCC1322.12c
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process ENSG00000156970
GO:0018209
IEA
PLAZA Integrative Orthologypeptidyl-serine modification SPCC1322.12c
GO:0072416
IEA
PLAZA Integrative Orthologysignal transduction involved in spindle checkpoint SPCC1322.12c
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process FBgn0263855
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0263855
GO:0018105
IEA
PLAZA Integrative Orthologypeptidyl-serine phosphorylation SPCC1322.12c
GO:0072413
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic cell cycle checkpoint SPCC1322.12c
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process FBgn0263855
GO:0010467
IEA
PLAZA Integrative Orthologygene expression FBgn0263855
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression FBgn0263855
GO:0031145
IEA
PLAZA Integrative Orthologyanaphase-promoting complex-dependent catabolic process ENSG00000156970
GO:0050000
IEA
PLAZA Integrative Orthologychromosome localization SPCC1322.12c
GO:0051177
IEA
PLAZA Integrative Orthologymeiotic sister chromatid cohesion SPCC1322.12c
GO:0070193
IEA
PLAZA Integrative Orthologysynaptonemal complex organization FBgn0263855
GO:0043161
IEA
PLAZA Integrative Orthologyproteasome-mediated ubiquitin-dependent protein catabolic process ENSG00000156970
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression FBgn0263855
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process FBgn0263855
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process FBgn0263855
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process YGR188C
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process FBgn0263855
GO:0007063
IEA
PLAZA Integrative Orthologyregulation of sister chromatid cohesion ENSG00000169679
GO:0007066
IEA
PLAZA Integrative Orthologyfemale meiosis sister chromatid cohesion FBgn0263855
GO:0007065
IEA
PLAZA Integrative Orthologymale meiosis sister chromatid cohesion FBgn0263855
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0263855
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process FBgn0263855
GO:0007062
IEA
PLAZA Integrative Orthologysister chromatid cohesion SPCC1322.12c
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process FBgn0263855
GO:0051603
IEA
PLAZA Integrative Orthologyproteolysis involved in cellular protein catabolic process ENSG00000156970
GO:0010458
IEA
PLAZA Integrative Orthologyexit from mitosis FBgn0263855
GO:0016572
IEA
PLAZA Integrative Orthologyhistone phosphorylation SPCC1322.12c
GO:0016570
IEA
PLAZA Integrative Orthologyhistone modification SPCC1322.12c
GO:0006914
IEA
PLAZA Integrative Orthologyautophagy YGR188C
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification SPCC1322.12c
GO:0060968
IEA
PLAZA Integrative Orthologyregulation of gene silencing FBgn0263855
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process FBgn0263855
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process FBgn0263855
GO:2001252
IEA
PLAZA Integrative Orthologypositive regulation of chromosome organization FBgn0263855
GO:0016569
IEA
PLAZA Integrative Orthologycovalent chromatin modification SPCC1322.12c
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0263855
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process FBgn0263855
GO:0051315
IEA
PLAZA Integrative Orthologyattachment of mitotic spindle microtubules to kinetochore SPCC1322.12c
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process FBgn0263855
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process FBgn0263855
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process FBgn0263855
GO:0007080
IEA
PLAZA Integrative Orthologymitotic metaphase plate congression SPCC1322.12c
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process FBgn0263855
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus SPCC1322.12c
GO:0035404
IEA
PLAZA Integrative Orthologyhistone-serine phosphorylation SPCC1322.12c
GO:0072477
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic spindle checkpoint SPCC1322.12c
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process FBgn0263855
GO:0051310
IEA
PLAZA Integrative Orthologymetaphase plate congression SPCC1322.12c
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic FBgn0263855
GO:1990164
IEA
PLAZA Integrative Orthologyhistone H2A phosphorylation SPCC1322.12c
GO:0072480
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic spindle assembly checkpoint SPCC1322.12c
GO:0061983
IEA
PLAZA Integrative Orthologymeiosis II cell cycle process SPCC1322.12c
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process FBgn0263855
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing FBgn0263855
GO:0016236
IEA
PLAZA Integrative Orthologymacroautophagy YGR188C
GO:0051303
IEA
PLAZA Integrative Orthologyestablishment of chromosome localization SPCC1322.12c
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0263855
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process FBgn0263855
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization FBgn0263855
GO:0072486
IEA
PLAZA Integrative Orthologysignal transduction involved in spindle assembly checkpoint SPCC1322.12c
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process FBgn0263855
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process FBgn0263855
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process FBgn0263855
GO:0061919
IEA
PLAZA Integrative Orthologyprocess utilizing autophagic mechanism YGR188C
GO:0070192
IEA
PLAZA Integrative Orthologychromosome organization involved in meiotic cell cycle SPCC1322.12c
GO:0072370
IEA
PLAZA Integrative Orthologyhistone H2A-S121 phosphorylation SPCC1322.12c
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process FBgn0263855
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process FBgn0263855
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process FBgn0263855
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process FBgn0263855
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process FBgn0263855
GO:0008283
IEA
PLAZA Integrative Orthologycell proliferation ENSG00000156970
GO:0051656
IEA
PLAZA Integrative Orthologyestablishment of organelle localization SPCC1322.12c
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription FBgn0263855
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process FBgn0263855
GO:0023052
IEA
PLAZA Integrative Orthologysignaling SPCC1322.12c
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization FBgn0263855
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process FBgn0263855
GO:0045144
IEA
PLAZA Integrative Orthologymeiotic sister chromatid segregation SPCC1322.12c
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process FBgn0263855
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process FBgn0263855
GO:0043632
IEA
PLAZA Integrative Orthologymodification-dependent macromolecule catabolic process ENSG00000156970
GO:0007140
IEA
PLAZA Integrative Orthologymale meiotic nuclear division FBgn0263855
GO:0007143
IEA
PLAZA Integrative Orthologyfemale meiotic nuclear division FBgn0263855
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic FBgn0263855
GO:0010498
IEA
PLAZA Integrative Orthologyproteasomal protein catabolic process ENSG00000156970
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction SPCC1322.12c
GO:0070601
IEA
PLAZA Integrative Orthologycentromeric sister chromatid cohesion SPCC1322.12c
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell SPCC1322.12c
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process FBgn0263855
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process FBgn0263855
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0263855
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated FBgn0263855
GO:0051640
IEA
PLAZA Integrative Orthologyorganelle localization SPCC1322.12c
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process FBgn0263855
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization SPCC1322.12c
GO:0007135
IEA
PLAZA Integrative Orthologymeiosis II SPCC1322.12c
GO:1902275
IEA
PLAZA Integrative Orthologyregulation of chromatin organization FBgn0263855
GO:0007096
IEA
PLAZA Integrative Orthologyregulation of exit from mitosis FBgn0263855
GO:1905269
IEA
PLAZA Integrative Orthologypositive regulation of chromatin organization FBgn0263855

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding4 5
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0035174
IEA
PLAZA Integrative Orthologyhistone serine kinase activity SPCC1322.12c
GO:0035173
IEA
PLAZA Integrative Orthologyhistone kinase activity SPCC1322.12c
GO:0072371
IEA
PLAZA Integrative Orthologyhistone kinase activity (H2A-S121 specific) SPCC1322.12c

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005938
IEA
Genome Projectcell cortex
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005694
IDA
IEA
Genome Projectchromosome
GO:0005694
IDA
Gene Ontologychromosome6
GO:0005634
IEA
Genome Projectnucleus
GO:0000777
IEA
Genome Projectcondensed chromosome kinetochore
GO:0000776
IDA
IEA
Genome Projectkinetochore
GO:0000776
IDA
Gene Ontologykinetochore2 3 4 5 6 7
GO:0000775
IEA
Genome Projectchromosome, centromeric region
GO:0005819
IEA
PLAZA Integrative Orthologyspindle ENSG00000156970
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000169679
GO:0005816
IEA
PLAZA Integrative Orthologyspindle pole body SPCC1322.12c
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part SPCC1322.12c
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen SPCC1322.12c
GO:0005815
IEA
PLAZA Integrative Orthologymicrotubule organizing center SPCC1322.12c
GO:0048471
IEA
PLAZA Integrative Orthologyperinuclear region of cytoplasm ENSG00000156970
GO:0005813
IEA
PLAZA Integrative Orthologycentrosome FBgn0031696
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex ENSG00000156970
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part SPCC1322.12c
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000169679
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex ENSG00000156970
GO:0000151
IEA
PLAZA Integrative Orthologyubiquitin ligase complex ENSG00000156970
GO:0000152
IEA
PLAZA Integrative Orthologynuclear ubiquitin ligase complex ENSG00000156970
GO:1990298
IEA
PLAZA Integrative Orthologybub1-bub3 complex SPCC1322.12c
GO:0000940
IEA
PLAZA Integrative Orthologycondensed chromosome outer kinetochore ENSG00000169679
GO:0000942
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome outer kinetochore ENSG00000169679
GO:0005680
IEA
PLAZA Integrative Orthologyanaphase-promoting complex ENSG00000156970
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000169679
GO:0000780
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome, centromeric region SPCC1322.12c
GO:0000778
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome kinetochore SPCC1322.12c
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton SPCC1322.12c
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton SPCC1322.12c
GO:0071957
IEA
PLAZA Integrative Orthologyold mitotic spindle pole body SPCC1322.12c
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen SPCC1322.12c
GO:0000794
IEA
PLAZA Integrative Orthologycondensed nuclear chromosome SPCC1322.12c
GO:0044732
IEA
PLAZA Integrative Orthologymitotic spindle pole body SPCC1322.12c
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPCC1322.12c
GO:0031461
IEA
PLAZA Integrative Orthologycullin-RING ubiquitin ligase complex ENSG00000156970
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen SPCC1322.12c
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPCC1322.12c
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen SPCC1322.12c
GO:0034506
IEA
PLAZA Integrative Orthologychromosome, centromeric core domain SPCC1322.12c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain superfamily
IPR015661Mitotic spindle checkpoint protein Bub1/Mad3
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.
KeggID Description
K02178BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
No chloroplast target sequence found.