Gene: SPBC17D11.02c (Schizosaccharomyces pombe)

Overview top

Gene Identifier
SPBC17D11.02c
Transcript Identifier
SPBC17D11.02c.1
Gene Type
Coding gene
Location
II : 3306554-3308630 : negative

Family Information

Homologous gene family
HOM02SEM001638
(36 genes in 25 species)
specific family

Descriptions

gene_descr
synviolin family ubiquitin-protein ligase E3, Hrd1

Identifiers

Type Value
pidSPBC17D11.02c.1:pep
UniprotO74757
RefSeq_mRNANM_001022297
EMBLCU329671

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030433
IMP
Genome Projectubiquitin-dependent ERAD pathway
GO:0030433
IMP
Gene Ontologyubiquitin-dependent ERAD pathway1
GO:0030968
ISO
Genome Projectendoplasmic reticulum unfolded protein response
GO:0010620
IMP
Genome Projectnegative regulation of transcription by transcription factor catabolism
GO:0010620
IMP
Gene Ontologynegative regulation of transcription by transcription factor catabolism1
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death ENSG00000162298
GO:0050821
IEA
PLAZA Integrative Orthologyprotein stabilization ENSG00000162298
GO:0048872
IEA
PLAZA Integrative Orthologyhomeostasis of number of cells FBgn0039875
GO:0043066
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic process ENSG00000162298
GO:0031647
IEA
PLAZA Integrative Orthologyregulation of protein stability ENSG00000162298
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization YOL013C
GO:0010608
IEA
PLAZA Integrative Orthologyposttranscriptional regulation of gene expression FBgn0039875
GO:0042886
IEA
PLAZA Integrative Orthologyamide transport YOL013C
GO:1901214
IEA
PLAZA Integrative Orthologyregulation of neuron death WBGene00009164
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth WBGene00004768
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway WBGene00004768
GO:1903513
IEA
PLAZA Integrative Orthologyendoplasmic reticulum to cytosol transport YOL013C
GO:0009100
IEA
PLAZA Integrative Orthologyglycoprotein metabolic process ENSG00000162298
GO:1905897
IEA
PLAZA Integrative Orthologyregulation of response to endoplasmic reticulum stress ENSG00000162298
GO:0009101
IEA
PLAZA Integrative Orthologyglycoprotein biosynthetic process ENSG00000162298
GO:0070936
IEA
PLAZA Integrative Orthologyprotein K48-linked ubiquitination ENSG00000162298
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00004768
GO:0051865
IEA
PLAZA Integrative Orthologyprotein autoubiquitination YOL013C
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00004768
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization YOL013C
GO:0034248
IEA
PLAZA Integrative Orthologyregulation of cellular amide metabolic process FBgn0039875
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus ENSG00000162298
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction ENSG00000162298
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000162298
GO:0045229
IEA
PLAZA Integrative Orthologyexternal encapsulating structure organization YOL013C
GO:1901566
IEA
PLAZA Integrative Orthologyorganonitrogen compound biosynthetic process ENSG00000162298
GO:1902532
IEA
PLAZA Integrative Orthologynegative regulation of intracellular signal transduction ENSG00000162298
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process YOL013C
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000162298
GO:0043603
IEA
PLAZA Integrative Orthologycellular amide metabolic process FBgn0039875
GO:0043604
IEA
PLAZA Integrative Orthologyamide biosynthetic process FBgn0039875
GO:0016567
IEA
PLAZA Integrative Orthologyprotein ubiquitination YOL013C
GO:0070997
IEA
PLAZA Integrative Orthologyneuron death WBGene00009164
GO:1904380
IEA
PLAZA Integrative Orthologyendoplasmic reticulum mannose trimming ENSG00000162298
GO:0030970
IEA
PLAZA Integrative Orthologyretrograde protein transport, ER to cytosol YOL013C
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YOL013C
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YOL013C
GO:0043043
IEA
PLAZA Integrative Orthologypeptide biosynthetic process FBgn0039875
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process FBgn0039875
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component ENSG00000159461
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway WBGene00004768
GO:0051179
IEA
PLAZA Integrative Orthologylocalization YOL013C
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function ENSG00000159461
GO:0045184
IEA
PLAZA Integrative Orthologyestablishment of protein localization YOL013C
GO:0006412
IEA
PLAZA Integrative Orthologytranslation FBgn0039875
GO:0043555
IEA
PLAZA Integrative Orthologyregulation of translation in response to stress FBgn0039875
GO:0006810
IEA
PLAZA Integrative Orthologytransport YOL013C
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process ENSG00000162298
GO:1903573
IEA
PLAZA Integrative Orthologynegative regulation of response to endoplasmic reticulum stress ENSG00000162298
GO:2001243
IEA
PLAZA Integrative Orthologynegative regulation of intrinsic apoptotic signaling pathway ENSG00000162298
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal YOL013C
GO:0071852
IEA
PLAZA Integrative Orthologyfungal-type cell wall organization or biogenesis YOL013C
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process ENSG00000162298
GO:0006518
IEA
PLAZA Integrative Orthologypeptide metabolic process FBgn0039875
GO:0043393
IEA
PLAZA Integrative Orthologyregulation of protein binding ENSG00000159461
GO:0018196
IEA
PLAZA Integrative Orthologypeptidyl-asparagine modification ENSG00000162298
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification ENSG00000162298
GO:0032527
IEA
PLAZA Integrative Orthologyprotein exit from endoplasmic reticulum YOL013C
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000159461
GO:0006517
IEA
PLAZA Integrative Orthologyprotein deglycosylation ENSG00000162298
GO:0070085
IEA
PLAZA Integrative Orthologyglycosylation ENSG00000162298
GO:0006886
IEA
PLAZA Integrative Orthologyintracellular protein transport YOL013C
GO:1902236
IEA
PLAZA Integrative Orthologynegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ENSG00000162298
GO:1902235
IEA
PLAZA Integrative Orthologyregulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ENSG00000162298
GO:0006487
IEA
PLAZA Integrative Orthologyprotein N-linked glycosylation ENSG00000162298
GO:0006486
IEA
PLAZA Integrative Orthologyprotein glycosylation ENSG00000162298
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000159461
GO:0032092
IEA
PLAZA Integrative Orthologypositive regulation of protein binding ENSG00000159461
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process YOL013C
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport YOL013C
GO:2001234
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic signaling pathway ENSG00000162298
GO:2001233
IEA
PLAZA Integrative Orthologyregulation of apoptotic signaling pathway ENSG00000162298
GO:0036335
IEA
PLAZA Integrative Orthologyintestinal stem cell homeostasis FBgn0039875
GO:0070059
IEA
PLAZA Integrative Orthologyintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ENSG00000162298
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000162298
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication ENSG00000162298
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification YOL013C
GO:0043413
IEA
PLAZA Integrative Orthologymacromolecule glycosylation ENSG00000162298
GO:1901137
IEA
PLAZA Integrative Orthologycarbohydrate derivative biosynthetic process ENSG00000162298
GO:1901135
IEA
PLAZA Integrative Orthologycarbohydrate derivative metabolic process ENSG00000162298
GO:0000209
IEA
PLAZA Integrative Orthologyprotein polyubiquitination ENSG00000162298
GO:2001242
IEA
PLAZA Integrative Orthologyregulation of intrinsic apoptotic signaling pathway ENSG00000162298
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport YOL013C
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization ENSG00000159461
GO:0036507
IEA
PLAZA Integrative Orthologyprotein demannosylation ENSG00000162298
GO:0071555
IEA
PLAZA Integrative Orthologycell wall organization YOL013C
GO:0071554
IEA
PLAZA Integrative Orthologycell wall organization or biogenesis YOL013C
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process FBgn0039875
GO:0036508
IEA
PLAZA Integrative Orthologyprotein alpha-1,2-demannosylation ENSG00000162298
GO:0006417
IEA
PLAZA Integrative Orthologyregulation of translation FBgn0039875
GO:0097193
IEA
PLAZA Integrative Orthologyintrinsic apoptotic signaling pathway ENSG00000162298
GO:0060548
IEA
PLAZA Integrative Orthologynegative regulation of cell death ENSG00000162298
GO:0097190
IEA
PLAZA Integrative Orthologyapoptotic signaling pathway ENSG00000162298
GO:0035264
IEA
PLAZA Integrative Orthologymulticellular organism growth WBGene00004768
GO:0051259
IEA
PLAZA Integrative Orthologyprotein complex oligomerization ENSG00000159461
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization YOL013C
GO:0015833
IEA
PLAZA Integrative Orthologypeptide transport YOL013C
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death ENSG00000162298
GO:0051098
IEA
PLAZA Integrative Orthologyregulation of binding ENSG00000159461
GO:0051099
IEA
PLAZA Integrative Orthologypositive regulation of binding ENSG00000159461
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000162298
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling ENSG00000162298
GO:0031505
IEA
PLAZA Integrative Orthologyfungal-type cell wall organization YOL013C
GO:0040007
IEA
PLAZA Integrative Orthologygrowth WBGene00004768
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function ENSG00000159461
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000162298
GO:0006457
IEA
PLAZA Integrative Orthologyprotein folding ENSG00000159461
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway WBGene00004768
GO:0046907
IEA
PLAZA Integrative Orthologyintracellular transport YOL013C
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly ENSG00000159461
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000162298
GO:0032446
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation YOL013C
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction ENSG00000162298
GO:0051649
IEA
PLAZA Integrative Orthologyestablishment of localization in cell YOL013C
GO:0018279
IEA
PLAZA Integrative Orthologyprotein N-linked glycosylation via asparagine ENSG00000162298
GO:0008219
IEA
PLAZA Integrative Orthologycell death ENSG00000162298
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization YOL013C
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process FBgn0039875
GO:0043069
IEA
PLAZA Integrative Orthologynegative regulation of programmed cell death ENSG00000162298
GO:0036490
IEA
PLAZA Integrative Orthologyregulation of translation in response to endoplasmic reticulum stress FBgn0039875
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress ENSG00000162298
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death ENSG00000162298
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress ENSG00000162298
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization YOL013C
GO:0015031
IEA
PLAZA Integrative Orthologyprotein transport YOL013C
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization YOL013C
GO:0036498
IEA
PLAZA Integrative OrthologyIRE1-mediated unfolded protein response ENSG00000162298

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008270
ISM
Gene Ontologyzinc ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1
GO:0061630
IDA
Genome Projectubiquitin protein ligase activity
GO:0061630
IDA, IMP
Gene Ontologyubiquitin protein ligase activity1
GO:0051117
IEA
PLAZA Integrative OrthologyATPase binding ENSG00000162298
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000162298
GO:0030674
IEA
PLAZA Integrative Orthologyprotein binding, bridging ENSG00000159461
GO:0051082
IEA
PLAZA Integrative Orthologyunfolded protein binding ENSG00000162298
GO:1904288
IEA
PLAZA Integrative OrthologyBAT3 complex binding ENSG00000159461
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000159461
GO:0002020
IEA
PLAZA Integrative Orthologyprotease binding ENSG00000162298
GO:0002039
IEA
PLAZA Integrative Orthologyp53 binding FBgn0039875
GO:0044877
IEA
PLAZA Integrative Orthologyprotein-containing complex binding ENSG00000159461
GO:0034450
IEA
PLAZA Integrative Orthologyubiquitin-ubiquitin ligase activity ENSG00000159461
GO:1990381
IEA
PLAZA Integrative Orthologyubiquitin-specific protease binding ENSG00000162298
GO:0038023
IEA
PLAZA Integrative Orthologysignaling receptor activity ENSG00000159461
GO:0060090
IEA
PLAZA Integrative Orthologymolecular adaptor activity ENSG00000159461
GO:0051087
IEA
PLAZA Integrative Orthologychaperone binding ENSG00000162298
GO:0060089
IEA
PLAZA Integrative Orthologymolecular transducer activity ENSG00000159461

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005938
IDA
Genome Projectcell cortex
GO:0005938
Gene Ontologycell cortex2
GO:0000836
ISO
Genome ProjectHrd1p ubiquitin ligase complex
GO:0000836
ISO
Gene OntologyHrd1p ubiquitin ligase complex
GO:0005789
ISO
Genome Projectendoplasmic reticulum membrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000162298
GO:0048471
IEA
PLAZA Integrative Orthologyperinuclear region of cytoplasm ENSG00000159461
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000162298
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000162298
GO:0030176
IEA
PLAZA Integrative Orthologyintegral component of endoplasmic reticulum membrane ENSG00000159461
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus ENSG00000159461
GO:0005790
IEA
PLAZA Integrative Orthologysmooth endoplasmic reticulum ENSG00000162298
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000162298
GO:0000838
IEA
PLAZA Integrative OrthologyHrd1p ubiquitin ligase ERAD-M complex YOL013C
GO:0000839
IEA
PLAZA Integrative OrthologyHrd1p ubiquitin ligase ERAD-L complex YOL013C
GO:0036513
IEA
PLAZA Integrative OrthologyDerlin-1 retrotranslocation complex ENSG00000162298
GO:0031227
IEA
PLAZA Integrative Orthologyintrinsic component of endoplasmic reticulum membrane ENSG00000159461
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000162298
GO:0005634
IEA
PLAZA Integrative Orthologynucleus ENSG00000162298
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane AT1G65040
GO:0044322
IEA
PLAZA Integrative Orthologyendoplasmic reticulum quality control compartment ENSG00000162298
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000162298

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR024766Zinc finger, RING-H2-type

No MapMan annotations defined for this gene.
KeggID Description
K10601SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
No chloroplast target sequence found.