Gene: FBgn0260985 (Drosophila melanogaster)

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Gene Identifier
FBgn0260985
Transcript Identifier
FBtr0073264
Gene Type
Coding gene
Location
3L : 4134936-4135983 : negative

Family Information

Homologous gene family
HOM02SEM000388
(90 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM002638
(28 genes in 26 species)
specific family

Descriptions

gene_descr
Replication factor C subunit 4

Identifiers

Type Value
pidFBpp0073120
UniprotP53034
RefSeq_mRNANM_079191.3
EMBLAE014296
EMBLAY094829
EMBLU15967

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0022008
IMP
Genome Projectneurogenesis
GO:0046331
IMP
Genome Projectlateral inhibition
GO:0007062
ISS
Genome Projectsister chromatid cohesion
GO:0007062
ISS
Gene Ontologysister chromatid cohesion
GO:0006272
ISS
Genome Projectleading strand elongation
GO:0006272
ISS
Gene Ontologyleading strand elongation
GO:0006260
IMP
TAS
Genome ProjectDNA replication
GO:0006260
IMP
TAS
Gene OntologyDNA replication1 2
GO:0000076
IMP
Genome ProjectDNA replication checkpoint
GO:0000076
IMP
Gene OntologyDNA replication checkpoint2
GO:0000077
IMP
Genome ProjectDNA damage checkpoint
GO:0000077
IMP
Gene OntologyDNA damage checkpoint2
GO:0007076
IMP
Genome Projectmitotic chromosome condensation
GO:0007076
Gene Ontologymitotic chromosome condensation3
GO:0000278
IMP
Genome Projectmitotic cell cycle
GO:0000278
Gene Ontologymitotic cell cycle3
GO:0016321
IMP
Genome Projectfemale meiosis chromosome segregation
GO:0016321
Gene Ontologyfemale meiosis chromosome segregation3
GO:0006281
TAS
Genome ProjectDNA repair
GO:0006281
TAS
Gene OntologyDNA repair1
GO:0006271
TAS
Genome ProjectDNA strand elongation involved in DNA replication
GO:0006271
TAS
Gene OntologyDNA strand elongation involved in DNA replication1
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000049541
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process ENSG00000049541
GO:0044786
IEA
PLAZA Integrative Orthologycell cycle DNA replication ENSG00000049541
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction ENSG00000049541
GO:0042769
IEA
PLAZA Integrative OrthologyDNA damage response, detection of DNA damage ENSG00000049541
GO:0051347
IEA
PLAZA Integrative Orthologypositive regulation of transferase activity ENSG00000049541
GO:2000573
IEA
PLAZA Integrative Orthologypositive regulation of DNA biosynthetic process ENSG00000049541
GO:0010557
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule biosynthetic process ENSG00000049541
GO:0071478
IEA
PLAZA Integrative Orthologycellular response to radiation SPAC1687.03c
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process ENSG00000049541
GO:0034644
IEA
PLAZA Integrative Orthologycellular response to UV SPAC1687.03c
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000049541
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000049541
GO:0033683
IEA
PLAZA Integrative Orthologynucleotide-excision repair, DNA incision ENSG00000049541
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000049541
GO:0051338
IEA
PLAZA Integrative Orthologyregulation of transferase activity ENSG00000049541
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus SPAC1687.03c
GO:0051054
IEA
PLAZA Integrative Orthologypositive regulation of DNA metabolic process ENSG00000049541
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000049541
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process ENSG00000049541
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function ENSG00000049541
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process ENSG00000049541
GO:1901796
IEA
PLAZA Integrative Orthologyregulation of signal transduction by p53 class mediator ENSG00000049541
GO:0090305
IEA
PLAZA Integrative Orthologynucleic acid phosphodiester bond hydrolysis ENSG00000049541
GO:0070914
IEA
PLAZA Integrative OrthologyUV-damage excision repair SPAC1687.03c
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus SPAC1687.03c
GO:2000278
IEA
PLAZA Integrative Orthologyregulation of DNA biosynthetic process ENSG00000049541
GO:0051606
IEA
PLAZA Integrative Orthologydetection of stimulus ENSG00000049541
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process ENSG00000049541
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus SPAC1687.03c
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process ENSG00000049541
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process ENSG00000049541
GO:0090329
IEA
PLAZA Integrative Orthologyregulation of DNA-dependent DNA replication ENSG00000049541
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process ENSG00000049541
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process ENSG00000049541
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process ENSG00000049541
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process ENSG00000049541
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000049541
GO:0031328
IEA
PLAZA Integrative Orthologypositive regulation of cellular biosynthetic process ENSG00000049541
GO:0006312
IEA
PLAZA Integrative Orthologymitotic recombination ENSG00000049541
GO:0000722
IEA
PLAZA Integrative Orthologytelomere maintenance via recombination ENSG00000049541
GO:0000723
IEA
PLAZA Integrative Orthologytelomere maintenance ENSG00000049541
GO:0006275
IEA
PLAZA Integrative Orthologyregulation of DNA replication ENSG00000049541
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination ENSG00000049541
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process ENSG00000049541
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis ENSG00000049541
GO:0070987
IEA
PLAZA Integrative Orthologyerror-free translesion synthesis ENSG00000049541
GO:0019985
IEA
PLAZA Integrative Orthologytranslesion synthesis ENSG00000049541
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process ENSG00000049541
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000049541
GO:0006301
IEA
PLAZA Integrative Orthologypostreplication repair ENSG00000049541
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus SPAC1687.03c
GO:0009411
IEA
PLAZA Integrative Orthologyresponse to UV SPAC1687.03c
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis ENSG00000049541
GO:0009891
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process ENSG00000049541
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000049541
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process ENSG00000049541
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process ENSG00000049541
GO:0072331
IEA
PLAZA Integrative Orthologysignal transduction by p53 class mediator ENSG00000049541
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity ENSG00000049541
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000049541
GO:0071482
IEA
PLAZA Integrative Orthologycellular response to light stimulus SPAC1687.03c
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000049541
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function ENSG00000049541
GO:0006298
IEA
PLAZA Integrative Orthologymismatch repair YOL094C
GO:0006297
IEA
PLAZA Integrative Orthologynucleotide-excision repair, DNA gap filling ENSG00000049541
GO:1900264
IEA
PLAZA Integrative Orthologypositive regulation of DNA-directed DNA polymerase activity ENSG00000049541
GO:1900262
IEA
PLAZA Integrative Orthologyregulation of DNA-directed DNA polymerase activity ENSG00000049541
GO:0006296
IEA
PLAZA Integrative Orthologynucleotide-excision repair, DNA incision, 5'-to lesion ENSG00000049541
GO:0045935
IEA
PLAZA Integrative Orthologypositive regulation of nucleobase-containing compound metabolic process ENSG00000049541
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality ENSG00000049541
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction ENSG00000049541
GO:0032200
IEA
PLAZA Integrative Orthologytelomere organization ENSG00000049541
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process ENSG00000049541
GO:0032201
IEA
PLAZA Integrative Orthologytelomere maintenance via semi-conservative replication ENSG00000049541
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity ENSG00000049541
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process ENSG00000049541
GO:0060249
IEA
PLAZA Integrative Orthologyanatomical structure homeostasis ENSG00000049541
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process ENSG00000049541
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process ENSG00000049541
GO:0000731
IEA
PLAZA Integrative OrthologyDNA synthesis involved in DNA repair ENSG00000049541
GO:0006289
IEA
PLAZA Integrative Orthologynucleotide-excision repair ENSG00000049541
GO:0009314
IEA
PLAZA Integrative Orthologyresponse to radiation SPAC1687.03c
GO:0033260
IEA
PLAZA Integrative Orthologynuclear DNA replication ENSG00000049541
GO:0006283
IEA
PLAZA Integrative Orthologytranscription-coupled nucleotide-excision repair ENSG00000049541

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003689
ISS, IBA
Genome ProjectDNA clamp loader activity
GO:0003689
ISS
Gene OntologyDNA clamp loader activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0003677
IMP
Genome ProjectDNA binding
GO:0003677
IMP
Gene OntologyDNA binding2
GO:0043142
IEA
PLAZA Integrative Orthologysingle-stranded DNA-dependent ATPase activity ENSG00000049541
GO:0061860
IEA
PLAZA Integrative OrthologyDNA clamp unloader activity SPAC1687.03c
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000049541

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031391
IDA
Genome ProjectElg1 RFC-like complex
GO:0031391
IDA
Gene OntologyElg1 RFC-like complex4
GO:0005663
ISS, IBA
Genome ProjectDNA replication factor C complex
GO:0005663
ISS
Gene OntologyDNA replication factor C complex
GO:0005875
IDA
Genome Projectmicrotubule associated complex
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus2
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen SPAC1687.03c
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part SPAC1687.03c
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000049541
GO:0031389
IEA
PLAZA Integrative OrthologyRad17 RFC-like complex YOL094C
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPAC1687.03c
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPAC1687.03c
GO:0031390
IEA
PLAZA Integrative OrthologyCtf18 RFC-like complex YOL094C
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC1687.03c
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPAC1687.03c
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen SPAC1687.03c
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPAC1687.03c
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen SPAC1687.03c
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC1687.03c
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPAC1687.03c
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen SPAC1687.03c
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPAC1687.03c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003593AAA+ ATPase domain
IPR003959ATPase, AAA-type, core
IPR008921DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
IPR013748Replication factor C, C-terminal
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K10755RFC2_4; replication factor C subunit 2/4
No chloroplast target sequence found.