Gene: FBgn0039044 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0039044
Transcript Identifier
FBtr0084360
Gene Type
Coding gene
Location
3R : 23049965-23054008 : negative

Family Information

Homologous gene family
HOM02SEM021028
(4 genes in 2 species)
specific family

Descriptions

gene_descr
p53

Identifiers

Type Value
pidFBpp0083753
UniprotD5AEJ5
UniprotQ2XVY6
UniprotQ2XVY7
UniprotQ8IH92
UniprotQ8IMZ4
RefSeq_mRNANM_206544.2
EMBLAE014297
EMBLBT001357
EMBLBT124732
EMBLDQ191318
EMBLDQ191319
EMBLDQ191320

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045944
IMP
IBA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IMP
Gene Ontologypositive regulation of transcription by RNA polymerase II1 2
GO:0034644
IBA
Genome Projectcellular response to UV
GO:0031571
IBA
Genome Projectmitotic G1 DNA damage checkpoint
GO:0006978
IBA
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0043523
IBA
Genome Projectregulation of neuron apoptotic process
GO:0000122
IBA
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0010212
IMP
Genome Projectresponse to ionizing radiation
GO:0010212
IMP
Gene Ontologyresponse to ionizing radiation3 4 5
GO:0060785
IMP
Genome Projectregulation of apoptosis involved in tissue homeostasis
GO:0060785
IMP
Gene Ontologyregulation of apoptosis involved in tissue homeostasis5
GO:0042771
IMP, IGI
TAS
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042771
IMP, IGI
TAS
Gene Ontologyintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator1 5 6 7 8 9 10
GO:1990248
IMP
Genome Projectregulation of transcription from RNA polymerase II promoter in response to DNA damage
GO:1990248
IMP
Gene Ontologyregulation of transcription from RNA polymerase II promoter in response to DNA damage5 11
GO:0040015
IGI
Genome Projectnegative regulation of multicellular organism growth
GO:0009267
IMP
Genome Projectcellular response to starvation
GO:0009267
IMP
Gene Ontologycellular response to starvation12 13
GO:0090278
IMP
Genome Projectnegative regulation of peptide hormone secretion
GO:0006357
IMP
TAS
Genome Projectregulation of transcription by RNA polymerase II
GO:0006357
IMP
TAS
Gene Ontologyregulation of transcription by RNA polymerase II14 15
GO:0042594
IMP
Genome Projectresponse to starvation
GO:0042594
IMP
Gene Ontologyresponse to starvation16
GO:0045893
IDA, IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
Gene Ontologypositive regulation of transcription, DNA-templated3 6 11
GO:0071480
IMP
Genome Projectcellular response to gamma radiation
GO:0071480
IMP
Gene Ontologycellular response to gamma radiation1 11
GO:0014016
IMP
Genome Projectneuroblast differentiation
GO:0014016
IMP
Gene Ontologyneuroblast differentiation17
GO:0007405
IMP
Genome Projectneuroblast proliferation
GO:0007405
IMP
Gene Ontologyneuroblast proliferation17
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0042127
IMP
Gene Ontologyregulation of cell proliferation18
GO:0046620
IMP
Genome Projectregulation of organ growth
GO:0046620
IMP
Gene Ontologyregulation of organ growth18
GO:0035234
IMP
Genome Projectectopic germ cell programmed cell death
GO:0035234
IMP
Gene Ontologyectopic germ cell programmed cell death19
GO:0007131
IMP
Genome Projectreciprocal meiotic recombination
GO:0007131
IMP
Gene Ontologyreciprocal meiotic recombination20
GO:0048477
IGI
Genome Projectoogenesis
GO:0048477
IGI
Gene Ontologyoogenesis20
GO:0046533
IMP
Genome Projectnegative regulation of photoreceptor cell differentiation
GO:0046533
IMP
Gene Ontologynegative regulation of photoreceptor cell differentiation21
GO:0006974
IDA, IMP
Genome Projectcellular response to DNA damage stimulus
GO:0006974
IMP
Gene Ontologycellular response to DNA damage stimulus22
GO:0016239
IMP
Genome Projectpositive regulation of macroautophagy
GO:0016239
IMP
Gene Ontologypositive regulation of macroautophagy12
GO:0008630
IMP
TAS
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008630
IMP
TAS
Gene Ontologyintrinsic apoptotic signaling pathway in response to DNA damage23 24
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919
IMP
Gene Ontologyactivation of cysteine-type endopeptidase activity involved in apoptotic process25
GO:0043568
IMP
Genome Projectpositive regulation of insulin-like growth factor receptor signaling pathway
GO:0043568
IMP
Gene Ontologypositive regulation of insulin-like growth factor receptor signaling pathway2
GO:0008340
IMP
Genome Projectdetermination of adult lifespan
GO:0008340
IMP
Gene Ontologydetermination of adult lifespan2 26
GO:0040018
IMP
Genome Projectpositive regulation of multicellular organism growth
GO:0040018
IMP
Gene Ontologypositive regulation of multicellular organism growth2
GO:0043553
IMP
Genome Projectnegative regulation of phosphatidylinositol 3-kinase activity
GO:0043553
IMP
Gene Ontologynegative regulation of phosphatidylinositol 3-kinase activity2
GO:0040010
IMP
Genome Projectpositive regulation of growth rate
GO:0040010
IMP
Gene Ontologypositive regulation of growth rate2
GO:0042246
IMP
Genome Projecttissue regeneration
GO:0042246
IMP
Gene Ontologytissue regeneration27
GO:0009411
IMP
Genome Projectresponse to UV
GO:0009411
IMP
Gene Ontologyresponse to UV28
GO:0045787
IGI
Genome Projectpositive regulation of cell cycle
GO:0045787
IGI
Gene Ontologypositive regulation of cell cycle29
GO:0006915
IMP
TAS
Genome Projectapoptotic process
GO:0006915
IMP
TAS
Gene Ontologyapoptotic process30 31 32
GO:2000685
IMP
Genome Projectpositive regulation of cellular response to X-ray
GO:2000685
IMP
Gene Ontologypositive regulation of cellular response to X-ray33
GO:0006282
IMP
Genome Projectregulation of DNA repair
GO:0006282
IMP
Gene Ontologyregulation of DNA repair33
GO:0009314
IMP
TAS
Genome Projectresponse to radiation
GO:0009314
IMP
TAS
Gene Ontologyresponse to radiation14 34
GO:0008219
IMP
Genome Projectcell death
GO:0008219
IMP
Gene Ontologycell death34
GO:0072332
IMP
Genome Projectintrinsic apoptotic signaling pathway by p53 class mediator
GO:0072332
IMP
Gene Ontologyintrinsic apoptotic signaling pathway by p53 class mediator1
GO:0030330
TAS
Genome ProjectDNA damage response, signal transduction by p53 class mediator
GO:0030330
TAS
Gene OntologyDNA damage response, signal transduction by p53 class mediator23 31
GO:0072716
IEA
PLAZA Integrative Orthologyresponse to actinomycin D ENSG00000141510
GO:0034599
IEA
PLAZA Integrative Orthologycellular response to oxidative stress ENSG00000141510
GO:0070897
IEA
PLAZA Integrative Orthologytranscription preinitiation complex assembly ENSG00000141510
GO:0043066
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic process ENSG00000141510
GO:0072395
IEA
PLAZA Integrative Orthologysignal transduction involved in cell cycle checkpoint ENSG00000141510
GO:0010608
IEA
PLAZA Integrative Orthologyposttranscriptional regulation of gene expression ENSG00000141510
GO:0007569
IEA
PLAZA Integrative Orthologycell aging ENSG00000141510
GO:0006352
IEA
PLAZA Integrative OrthologyDNA-templated transcription, initiation ENSG00000141510
GO:0035690
IEA
PLAZA Integrative Orthologycellular response to drug ENSG00000141510
GO:0061024
IEA
PLAZA Integrative Orthologymembrane organization ENSG00000141510
GO:0072717
IEA
PLAZA Integrative Orthologycellular response to actinomycin D ENSG00000141510
GO:0016032
IEA
PLAZA Integrative Orthologyviral process ENSG00000141510
GO:0008637
IEA
PLAZA Integrative Orthologyapoptotic mitochondrial changes ENSG00000141510
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process ENSG00000141510
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus ENSG00000141510
GO:0051346
IEA
PLAZA Integrative Orthologynegative regulation of hydrolase activity ENSG00000141510
GO:0044257
IEA
PLAZA Integrative Orthologycellular protein catabolic process ENSG00000141510
GO:0046677
IEA
PLAZA Integrative Orthologyresponse to antibiotic ENSG00000141510
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process ENSG00000141510
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization ENSG00000141510
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process ENSG00000141510
GO:0009299
IEA
PLAZA Integrative OrthologymRNA transcription ENSG00000141510
GO:0016049
IEA
PLAZA Integrative Orthologycell growth ENSG00000141510
GO:1900739
IEA
PLAZA Integrative Orthologyregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway ENSG00000141510
GO:0043161
IEA
PLAZA Integrative Orthologyproteasome-mediated ubiquitin-dependent protein catabolic process ENSG00000141510
GO:1900740
IEA
PLAZA Integrative Orthologypositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway ENSG00000141510
GO:1901030
IEA
PLAZA Integrative Orthologypositive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ENSG00000141510
GO:0051205
IEA
PLAZA Integrative Orthologyprotein insertion into membrane ENSG00000141510
GO:0070646
IEA
PLAZA Integrative Orthologyprotein modification by small protein removal ENSG00000141510
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus ENSG00000141510
GO:0051204
IEA
PLAZA Integrative Orthologyprotein insertion into mitochondrial membrane ENSG00000141510
GO:0060964
IEA
PLAZA Integrative Orthologyregulation of gene silencing by miRNA ENSG00000141510
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal ENSG00000141510
GO:0006367
IEA
PLAZA Integrative Orthologytranscription initiation from RNA polymerase II promoter ENSG00000141510
GO:1901700
IEA
PLAZA Integrative Orthologyresponse to oxygen-containing compound ENSG00000141510
GO:0060968
IEA
PLAZA Integrative Orthologyregulation of gene silencing ENSG00000141510
GO:1901701
IEA
PLAZA Integrative Orthologycellular response to oxygen-containing compound ENSG00000141510
GO:1901028
IEA
PLAZA Integrative Orthologyregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ENSG00000141510
GO:0060966
IEA
PLAZA Integrative Orthologyregulation of gene silencing by RNA ENSG00000141510
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000141510
GO:1902110
IEA
PLAZA Integrative Orthologypositive regulation of mitochondrial membrane permeability involved in apoptotic process ENSG00000141510
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process ENSG00000141510
GO:0010243
IEA
PLAZA Integrative Orthologyresponse to organonitrogen compound ENSG00000141510
GO:0031047
IEA
PLAZA Integrative Orthologygene silencing by RNA ENSG00000141510
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic ENSG00000141510
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization ENSG00000141510
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification ENSG00000141510
GO:1901653
IEA
PLAZA Integrative Orthologycellular response to peptide ENSG00000141510
GO:1901652
IEA
PLAZA Integrative Orthologyresponse to peptide ENSG00000141510
GO:0031050
IEA
PLAZA Integrative OrthologydsRNA processing ENSG00000141510
GO:0016579
IEA
PLAZA Integrative Orthologyprotein deubiquitination ENSG00000141510
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing ENSG00000141510
GO:0072401
IEA
PLAZA Integrative Orthologysignal transduction involved in DNA integrity checkpoint ENSG00000141510
GO:0070585
IEA
PLAZA Integrative Orthologyprotein localization to mitochondrion ENSG00000141510
GO:0051262
IEA
PLAZA Integrative Orthologyprotein tetramerization ENSG00000141510
GO:0097345
IEA
PLAZA Integrative Orthologymitochondrial outer membrane permeabilization ENSG00000141510
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance ENSG00000141510
GO:0060548
IEA
PLAZA Integrative Orthologynegative regulation of cell death ENSG00000141510
GO:0090150
IEA
PLAZA Integrative Orthologyestablishment of protein localization to membrane ENSG00000141510
GO:0090398
IEA
PLAZA Integrative Orthologycellular senescence ENSG00000141510
GO:0008285
IEA
PLAZA Integrative Orthologynegative regulation of cell proliferation ENSG00000141510
GO:0090399
IEA
PLAZA Integrative Orthologyreplicative senescence ENSG00000141510
GO:0051259
IEA
PLAZA Integrative Orthologyprotein complex oligomerization ENSG00000141510
GO:0032392
IEA
PLAZA Integrative OrthologyDNA geometric change ENSG00000141510
GO:0010822
IEA
PLAZA Integrative Orthologypositive regulation of mitochondrion organization ENSG00000141510
GO:0010821
IEA
PLAZA Integrative Orthologyregulation of mitochondrion organization ENSG00000141510
GO:0009719
IEA
PLAZA Integrative Orthologyresponse to endogenous stimulus ENSG00000141510
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization ENSG00000141510
GO:0001558
IEA
PLAZA Integrative Orthologyregulation of cell growth ENSG00000141510
GO:0043632
IEA
PLAZA Integrative Orthologymodification-dependent macromolecule catabolic process ENSG00000141510
GO:0046902
IEA
PLAZA Integrative Orthologyregulation of mitochondrial membrane permeability ENSG00000141510
GO:0006333
IEA
PLAZA Integrative Orthologychromatin assembly or disassembly ENSG00000141510
GO:0051260
IEA
PLAZA Integrative Orthologyprotein homooligomerization ENSG00000141510
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process ENSG00000141510
GO:0035794
IEA
PLAZA Integrative Orthologypositive regulation of mitochondrial membrane permeability ENSG00000141510
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance ENSG00000141510
GO:0010498
IEA
PLAZA Integrative Orthologyproteasomal protein catabolic process ENSG00000141510
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization ENSG00000141510
GO:0034349
IEA
PLAZA Integrative Orthologyglial cell apoptotic process ENSG00000141510
GO:0071417
IEA
PLAZA Integrative Orthologycellular response to organonitrogen compound ENSG00000141510
GO:2000637
IEA
PLAZA Integrative Orthologypositive regulation of gene silencing by miRNA ENSG00000141510
GO:0071897
IEA
PLAZA Integrative OrthologyDNA biosynthetic process ENSG00000141510
GO:0030308
IEA
PLAZA Integrative Orthologynegative regulation of cell growth ENSG00000141510
GO:0001666
IEA
PLAZA Integrative Orthologyresponse to hypoxia ENSG00000141510
GO:0051123
IEA
PLAZA Integrative OrthologyRNA polymerase II preinitiation complex assembly ENSG00000141510
GO:0006323
IEA
PLAZA Integrative OrthologyDNA packaging ENSG00000141510
GO:0097252
IEA
PLAZA Integrative Orthologyoligodendrocyte apoptotic process ENSG00000141510
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization ENSG00000141510
GO:0043069
IEA
PLAZA Integrative Orthologynegative regulation of programmed cell death ENSG00000141510
GO:1903800
IEA
PLAZA Integrative Orthologypositive regulation of production of miRNAs involved in gene silencing by miRNA ENSG00000141510
GO:0061614
IEA
PLAZA Integrative Orthologypri-miRNA transcription by RNA polymerase II ENSG00000141510
GO:0044839
IEA
PLAZA Integrative Orthologycell cycle G2/M phase transition ENSG00000141510
GO:0032459
IEA
PLAZA Integrative Orthologyregulation of protein oligomerization ENSG00000141510
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000141510
GO:0071103
IEA
PLAZA Integrative OrthologyDNA conformation change ENSG00000141510
GO:0042493
IEA
PLAZA Integrative Orthologyresponse to drug ENSG00000141510
GO:0072431
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic G1 DNA damage checkpoint ENSG00000141510
GO:0006511
IEA
PLAZA Integrative Orthologyubiquitin-dependent protein catabolic process ENSG00000141510
GO:1901698
IEA
PLAZA Integrative Orthologyresponse to nitrogen compound ENSG00000141510
GO:1901699
IEA
PLAZA Integrative Orthologycellular response to nitrogen compound ENSG00000141510
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process ENSG00000141510
GO:0030163
IEA
PLAZA Integrative Orthologyprotein catabolic process ENSG00000141510
GO:0090400
IEA
PLAZA Integrative Orthologystress-induced premature senescence ENSG00000141510
GO:0032461
IEA
PLAZA Integrative Orthologypositive regulation of protein oligomerization ENSG00000141510
GO:0090403
IEA
PLAZA Integrative Orthologyoxidative stress-induced premature senescence ENSG00000141510
GO:0019941
IEA
PLAZA Integrative Orthologymodification-dependent protein catabolic process ENSG00000141510
GO:0071236
IEA
PLAZA Integrative Orthologycellular response to antibiotic ENSG00000141510
GO:0031497
IEA
PLAZA Integrative Orthologychromatin assembly ENSG00000141510
GO:0001844
IEA
PLAZA Integrative Orthologyprotein insertion into mitochondrial membrane involved in apoptotic signaling pathway ENSG00000141510
GO:0006977
IEA
PLAZA Integrative OrthologyDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ENSG00000141510
GO:0006979
IEA
PLAZA Integrative Orthologyresponse to oxidative stress ENSG00000141510
GO:1903747
IEA
PLAZA Integrative Orthologyregulation of establishment of protein localization to mitochondrion ENSG00000141510
GO:0006984
IEA
PLAZA Integrative OrthologyER-nucleus signaling pathway ENSG00000141510
GO:1900119
IEA
PLAZA Integrative Orthologypositive regulation of execution phase of apoptosis ENSG00000141510
GO:0006983
IEA
PLAZA Integrative OrthologyER overload response ENSG00000141510
GO:1903749
IEA
PLAZA Integrative Orthologypositive regulation of establishment of protein localization to mitochondrion ENSG00000141510
GO:1900117
IEA
PLAZA Integrative Orthologyregulation of execution phase of apoptosis ENSG00000141510
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction ENSG00000141510
GO:1902895
IEA
PLAZA Integrative Orthologypositive regulation of pri-miRNA transcription by RNA polymerase II ENSG00000141510
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process ENSG00000141510
GO:0090199
IEA
PLAZA Integrative Orthologyregulation of release of cytochrome c from mitochondria ENSG00000141510
GO:1902893
IEA
PLAZA Integrative Orthologyregulation of pri-miRNA transcription by RNA polymerase II ENSG00000141510
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000141510
GO:0044419
IEA
PLAZA Integrative Orthologyinterspecies interaction between organisms ENSG00000141510
GO:0034097
IEA
PLAZA Integrative Orthologyresponse to cytokine ENSG00000141510
GO:0051974
IEA
PLAZA Integrative Orthologynegative regulation of telomerase activity ENSG00000141510
GO:0072655
IEA
PLAZA Integrative Orthologyestablishment of protein localization to mitochondrion ENSG00000141510
GO:0072413
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic cell cycle checkpoint ENSG00000141510
GO:0016441
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing ENSG00000141510
GO:0072657
IEA
PLAZA Integrative Orthologyprotein localization to membrane ENSG00000141510
GO:0051053
IEA
PLAZA Integrative Orthologynegative regulation of DNA metabolic process ENSG00000141510
GO:0051972
IEA
PLAZA Integrative Orthologyregulation of telomerase activity ENSG00000141510
GO:0046825
IEA
PLAZA Integrative Orthologyregulation of protein export from nucleus ENSG00000141510
GO:0044403
IEA
PLAZA Integrative Orthologysymbiont process ENSG00000141510
GO:1902400
IEA
PLAZA Integrative Orthologyintracellular signal transduction involved in G1 DNA damage checkpoint ENSG00000141510
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical ENSG00000141510
GO:1902402
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic DNA damage checkpoint ENSG00000141510
GO:1902403
IEA
PLAZA Integrative Orthologysignal transduction involved in mitotic DNA integrity checkpoint ENSG00000141510
GO:1901796
IEA
PLAZA Integrative Orthologyregulation of signal transduction by p53 class mediator ENSG00000141510
GO:0070918
IEA
PLAZA Integrative Orthologyproduction of small RNA involved in gene silencing by RNA ENSG00000141510
GO:1905477
IEA
PLAZA Integrative Orthologypositive regulation of protein localization to membrane ENSG00000141510
GO:0035195
IEA
PLAZA Integrative Orthologygene silencing by miRNA ENSG00000141510
GO:0035196
IEA
PLAZA Integrative Orthologyproduction of miRNAs involved in gene silencing by miRNA ENSG00000141510
GO:0035194
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing by RNA ENSG00000141510
GO:0046827
IEA
PLAZA Integrative Orthologypositive regulation of protein export from nucleus ENSG00000141510
GO:1905475
IEA
PLAZA Integrative Orthologyregulation of protein localization to membrane ENSG00000141510
GO:2000279
IEA
PLAZA Integrative Orthologynegative regulation of DNA biosynthetic process ENSG00000141510
GO:0070920
IEA
PLAZA Integrative Orthologyregulation of production of small RNA involved in gene silencing by RNA ENSG00000141510
GO:0051603
IEA
PLAZA Integrative Orthologyproteolysis involved in cellular protein catabolic process ENSG00000141510
GO:2001244
IEA
PLAZA Integrative Orthologypositive regulation of intrinsic apoptotic signaling pathway ENSG00000141510
GO:0071456
IEA
PLAZA Integrative Orthologycellular response to hypoxia ENSG00000141510
GO:0071216
IEA
PLAZA Integrative Orthologycellular response to biotic stimulus ENSG00000141510
GO:2000278
IEA
PLAZA Integrative Orthologyregulation of DNA biosynthetic process ENSG00000141510
GO:0044089
IEA
PLAZA Integrative Orthologypositive regulation of cellular component biogenesis ENSG00000141510
GO:0072422
IEA
PLAZA Integrative Orthologysignal transduction involved in DNA damage checkpoint ENSG00000141510
GO:0071453
IEA
PLAZA Integrative Orthologycellular response to oxygen levels ENSG00000141510
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis ENSG00000141510
GO:0051168
IEA
PLAZA Integrative Orthologynuclear export ENSG00000141510
GO:0051289
IEA
PLAZA Integrative Orthologyprotein homotetramerization ENSG00000141510
GO:1902749
IEA
PLAZA Integrative Orthologyregulation of cell cycle G2/M phase transition ENSG00000141510
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000141510
GO:0070482
IEA
PLAZA Integrative Orthologyresponse to oxygen levels ENSG00000141510
GO:0036293
IEA
PLAZA Integrative Orthologyresponse to decreased oxygen levels ENSG00000141510
GO:0036294
IEA
PLAZA Integrative Orthologycellular response to decreased oxygen levels ENSG00000141510
GO:0007050
IEA
PLAZA Integrative Orthologycell cycle arrest ENSG00000141510
GO:2001235
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic signaling pathway ENSG00000141510
GO:2001233
IEA
PLAZA Integrative Orthologyregulation of apoptotic signaling pathway ENSG00000141510
GO:0071824
IEA
PLAZA Integrative Orthologyprotein-DNA complex subunit organization ENSG00000141510
GO:2000144
IEA
PLAZA Integrative Orthologypositive regulation of DNA-templated transcription, initiation ENSG00000141510
GO:0072593
IEA
PLAZA Integrative Orthologyreactive oxygen species metabolic process ENSG00000141510
GO:0007006
IEA
PLAZA Integrative Orthologymitochondrial membrane organization ENSG00000141510
GO:1902108
IEA
PLAZA Integrative Orthologyregulation of mitochondrial membrane permeability involved in apoptotic process ENSG00000141510
GO:0007005
IEA
PLAZA Integrative Orthologymitochondrion organization ENSG00000141510
GO:1903798
IEA
PLAZA Integrative Orthologyregulation of production of miRNAs involved in gene silencing by miRNA ENSG00000141510
GO:0006396
IEA
PLAZA Integrative OrthologyRNA processing ENSG00000141510
GO:0090200
IEA
PLAZA Integrative Orthologypositive regulation of release of cytochrome c from mitochondria ENSG00000141510
GO:0043254
IEA
PLAZA Integrative Orthologyregulation of protein complex assembly ENSG00000141510
GO:2001242
IEA
PLAZA Integrative Orthologyregulation of intrinsic apoptotic signaling pathway ENSG00000141510
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization ENSG00000141510
GO:0031334
IEA
PLAZA Integrative Orthologypositive regulation of protein complex assembly ENSG00000141510
GO:0090559
IEA
PLAZA Integrative Orthologyregulation of membrane permeability ENSG00000141510
GO:2000379
IEA
PLAZA Integrative Orthologypositive regulation of reactive oxygen species metabolic process ENSG00000141510
GO:0071158
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle arrest ENSG00000141510
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization ENSG00000141510
GO:2000377
IEA
PLAZA Integrative Orthologyregulation of reactive oxygen species metabolic process ENSG00000141510
GO:0048145
IEA
PLAZA Integrative Orthologyregulation of fibroblast proliferation ENSG00000141510
GO:0048147
IEA
PLAZA Integrative Orthologynegative regulation of fibroblast proliferation ENSG00000141510
GO:0019221
IEA
PLAZA Integrative Orthologycytokine-mediated signaling pathway ENSG00000141510
GO:0071156
IEA
PLAZA Integrative Orthologyregulation of cell cycle arrest ENSG00000141510
GO:0016071
IEA
PLAZA Integrative OrthologymRNA metabolic process ENSG00000141510
GO:0048144
IEA
PLAZA Integrative Orthologyfibroblast proliferation ENSG00000141510
GO:0097194
IEA
PLAZA Integrative Orthologyexecution phase of apoptosis ENSG00000141510
GO:0060148
IEA
PLAZA Integrative Orthologypositive regulation of posttranscriptional gene silencing ENSG00000141510
GO:0060147
IEA
PLAZA Integrative Orthologyregulation of posttranscriptional gene silencing ENSG00000141510
GO:0048017
IEA
PLAZA Integrative Orthologyinositol lipid-mediated signaling ENSG00000141510
GO:0060261
IEA
PLAZA Integrative Orthologypositive regulation of transcription initiation from RNA polymerase II promoter ENSG00000141510
GO:0060260
IEA
PLAZA Integrative Orthologyregulation of transcription initiation from RNA polymerase II promoter ENSG00000141510
GO:2000142
IEA
PLAZA Integrative Orthologyregulation of DNA-templated transcription, initiation ENSG00000141510
GO:0034976
IEA
PLAZA Integrative Orthologyresponse to endoplasmic reticulum stress ENSG00000141510
GO:0001836
IEA
PLAZA Integrative Orthologyrelease of cytochrome c from mitochondria ENSG00000141510
GO:0051097
IEA
PLAZA Integrative Orthologynegative regulation of helicase activity ENSG00000141510
GO:0048015
IEA
PLAZA Integrative Orthologyphosphatidylinositol-mediated signaling ENSG00000141510
GO:0045899
IEA
PLAZA Integrative Orthologypositive regulation of RNA polymerase II transcriptional preinitiation complex assembly ENSG00000141510
GO:0045898
IEA
PLAZA Integrative Orthologyregulation of RNA polymerase II transcriptional preinitiation complex assembly ENSG00000141510
GO:0042149
IEA
PLAZA Integrative Orthologycellular response to glucose starvation ENSG00000141510
GO:0006611
IEA
PLAZA Integrative Orthologyprotein export from nucleus ENSG00000141510
GO:0007265
IEA
PLAZA Integrative OrthologyRas protein signal transduction ENSG00000141510
GO:1902686
IEA
PLAZA Integrative Orthologymitochondrial outer membrane permeabilization involved in programmed cell death ENSG00000141510
GO:0065004
IEA
PLAZA Integrative Orthologyprotein-DNA complex assembly ENSG00000141510
GO:0007264
IEA
PLAZA Integrative Orthologysmall GTPase mediated signal transduction ENSG00000141510
GO:1905710
IEA
PLAZA Integrative Orthologypositive regulation of membrane permeability ENSG00000141510
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly ENSG00000141510
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly ENSG00000141510
GO:0071495
IEA
PLAZA Integrative Orthologycellular response to endogenous stimulus ENSG00000141510
GO:0006839
IEA
PLAZA Integrative Orthologymitochondrial transport ENSG00000141510
GO:0006289
IEA
PLAZA Integrative Orthologynucleotide-excision repair ENSG00000141510
GO:0000733
IEA
PLAZA Integrative OrthologyDNA strand renaturation ENSG00000141510
GO:0051095
IEA
PLAZA Integrative Orthologyregulation of helicase activity ENSG00000141510
GO:0006284
IEA
PLAZA Integrative Orthologybase-excision repair ENSG00000141510
GO:0010940
IMP
Gene Ontologypositive regulation of necrotic cell death35
GO:0042307
IMP
Gene Ontologypositive regulation of protein import into nucleus2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003682
IBA
Genome Projectchromatin binding
GO:0002039
IBA
Genome Projectp53 binding
GO:0003684
IBA
Genome Projectdamaged DNA binding
GO:0003700
IBA
Genome ProjectDNA-binding transcription factor activity
GO:0000976
IDA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000976
IDA
Gene Ontologytranscription regulatory region sequence-specific DNA binding36
GO:0001047
IDA
Genome Projectcore promoter binding
GO:0001097
IPI
Genome ProjectTFIIH-class transcription factor complex binding
GO:0001097
IPI
Gene OntologyTFIIH-class transcription factor complex binding37
GO:0031624
IPI
Genome Projectubiquitin conjugating enzyme binding
GO:0031624
IPI
Gene Ontologyubiquitin conjugating enzyme binding10
GO:0001085
IPI
Genome ProjectRNA polymerase II transcription factor binding
GO:0001085
IPI
Gene OntologyRNA polymerase II transcription factor binding38
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008134
IPI
Gene Ontologytranscription factor binding38
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 39
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0031625
IPI
Gene Ontologyubiquitin protein ligase binding39
GO:0030554
IEA
PLAZA Integrative Orthologyadenyl nucleotide binding ENSG00000141510
GO:0043168
IEA
PLAZA Integrative Orthologyanion binding ENSG00000141510
GO:0043169
IEA
PLAZA Integrative Orthologycation binding ENSG00000141510
GO:0043167
IEA
PLAZA Integrative Orthologyion binding ENSG00000141510
GO:0001228
IEA
PLAZA Integrative OrthologyDNA-binding transcription activator activity, RNA polymerase II-specific ENSG00000141510
GO:1901265
IEA
PLAZA Integrative Orthologynucleoside phosphate binding ENSG00000141510
GO:0005102
IEA
PLAZA Integrative Orthologysignaling receptor binding ENSG00000141510
GO:0001094
IEA
PLAZA Integrative OrthologyTFIID-class transcription factor complex binding ENSG00000141510
GO:0046914
IEA
PLAZA Integrative Orthologytransition metal ion binding ENSG00000141510
GO:0003729
IEA
PLAZA Integrative OrthologymRNA binding ENSG00000141510
GO:0097367
IEA
PLAZA Integrative Orthologycarbohydrate derivative binding ENSG00000141510
GO:0003723
IEA
PLAZA Integrative OrthologyRNA binding ENSG00000141510
GO:0003730
IEA
PLAZA Integrative OrthologymRNA 3'-UTR binding ENSG00000141510
GO:0043621
IEA
PLAZA Integrative Orthologyprotein self-association ENSG00000141510
GO:0097371
IEA
PLAZA Homology (enrichment)MDM2/MDM4 family protein binding HOM02SEM021028
GO:0036094
IEA
PLAZA Integrative Orthologysmall molecule binding ENSG00000141510
GO:0097718
IEA
PLAZA Integrative Orthologydisordered domain specific binding ENSG00000141510
GO:0017076
IEA
PLAZA Integrative Orthologypurine nucleotide binding ENSG00000141510
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000141510
GO:0005524
IEA
PLAZA Integrative OrthologyATP binding ENSG00000141510
GO:0002020
IEA
PLAZA Integrative Orthologyprotease binding ENSG00000141510
GO:0030971
IEA
PLAZA Integrative Orthologyreceptor tyrosine kinase binding ENSG00000141510
GO:0047485
IEA
PLAZA Integrative Orthologyprotein N-terminus binding ENSG00000141510
GO:0008270
IEA
PLAZA Integrative Orthologyzinc ion binding ENSG00000141510
GO:0051721
IEA
PLAZA Integrative Orthologyprotein phosphatase 2A binding ENSG00000141510
GO:0001074
IEA
PLAZA Integrative Orthologytranscription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly ENSG00000141510
GO:0035639
IEA
PLAZA Integrative Orthologypurine ribonucleoside triphosphate binding ENSG00000141510
GO:0008144
IEA
PLAZA Integrative Orthologydrug binding ENSG00000141510
GO:0019900
IEA
PLAZA Integrative Orthologykinase binding ENSG00000141510
GO:0001012
IEA
PLAZA Integrative OrthologyRNA polymerase II regulatory region DNA binding ENSG00000141510
GO:1990782
IEA
PLAZA Integrative Orthologyprotein tyrosine kinase binding ENSG00000141510
GO:0000166
IEA
PLAZA Integrative Orthologynucleotide binding ENSG00000141510
GO:0032555
IEA
PLAZA Integrative Orthologypurine ribonucleotide binding ENSG00000141510
GO:0032553
IEA
PLAZA Integrative Orthologyribonucleotide binding ENSG00000141510
GO:0046872
IEA
PLAZA Integrative Orthologymetal ion binding ENSG00000141510
GO:0032559
IEA
PLAZA Integrative Orthologyadenyl ribonucleotide binding ENSG00000141510
GO:0001046
IEA
PLAZA Integrative Orthologycore promoter sequence-specific DNA binding ENSG00000141510
GO:0000981
IEA
PLAZA Integrative OrthologyDNA-binding transcription factor activity, RNA polymerase II-specific ENSG00000141510
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000141510
GO:0000987
IEA
PLAZA Integrative Orthologyproximal promoter sequence-specific DNA binding ENSG00000141510
GO:0042826
IEA
PLAZA Integrative Orthologyhistone deacetylase binding ENSG00000141510
GO:0019903
IEA
PLAZA Integrative Orthologyprotein phosphatase binding ENSG00000141510
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding ENSG00000141510
GO:0035035
IEA
PLAZA Integrative Orthologyhistone acetyltransferase binding ENSG00000141510
GO:0019901
IEA
PLAZA Integrative Orthologyprotein kinase binding ENSG00000141510
GO:0019902
IEA
PLAZA Integrative Orthologyphosphatase binding ENSG00000141510
GO:0051087
IEA
PLAZA Integrative Orthologychaperone binding ENSG00000141510
GO:0046982
IEA
PLAZA Integrative Orthologyprotein heterodimerization activity ENSG00000141510
GO:0005507
IEA
PLAZA Integrative Orthologycopper ion binding ENSG00000141510
GO:0000978
IEA
PLAZA Integrative OrthologyRNA polymerase II proximal promoter sequence-specific DNA binding ENSG00000141510
GO:0000977
IEA
PLAZA Integrative OrthologyRNA polymerase II regulatory region sequence-specific DNA binding ENSG00000141510
GO:1990841
IDA
Gene Ontologypromoter-specific chromatin binding11

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005667
IBA
Genome Projecttranscription factor complex
GO:0005829
IBA
Genome Projectcytosol
GO:0010369
IDA
Genome Projectchromocenter
GO:0010369
IDA
Gene Ontologychromocenter5
GO:0035327
IDA
Genome Projecttranscriptionally active chromatin
GO:0035327
IDA
Gene Ontologytranscriptionally active chromatin40
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus40
GO:0055029
IEA
PLAZA Integrative Orthologynuclear DNA-directed RNA polymerase complex ENSG00000141510
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex ENSG00000141510
GO:0016605
IEA
PLAZA Integrative OrthologyPML body ENSG00000141510
GO:0016604
IEA
PLAZA Integrative Orthologynuclear body ENSG00000141510
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000141510
GO:0030880
IEA
PLAZA Integrative OrthologyRNA polymerase complex ENSG00000141510
GO:0016591
IEA
PLAZA Integrative OrthologyRNA polymerase II, holoenzyme ENSG00000141510
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000141510
GO:0016363
IEA
PLAZA Integrative Orthologynuclear matrix ENSG00000141510
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome ENSG00000141510
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000141510
GO:1990234
IEA
PLAZA Integrative Orthologytransferase complex ENSG00000141510
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000141510
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000141510
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin ENSG00000141510
GO:0000428
IEA
PLAZA Integrative OrthologyDNA-directed RNA polymerase complex ENSG00000141510
GO:0005669
IEA
PLAZA Integrative Orthologytranscription factor TFIID complex ENSG00000141510
GO:0034399
IEA
PLAZA Integrative Orthologynuclear periphery ENSG00000141510
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion ENSG00000141510
GO:0005730
IEA
PLAZA Integrative Orthologynucleolus ENSG00000141510
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part ENSG00000141510
GO:0044451
IEA
PLAZA Integrative Orthologynucleoplasm part ENSG00000141510
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000141510
GO:0044798
IEA
PLAZA Integrative Orthologynuclear transcription factor complex ENSG00000141510
GO:0090575
IEA
PLAZA Integrative OrthologyRNA polymerase II transcription factor complex ENSG00000141510
GO:0061695
IEA
PLAZA Integrative Orthologytransferase complex, transferring phosphorus-containing groups ENSG00000141510

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002117p53 tumour suppressor family
IPR008967p53-like transcription factor, DNA-binding
IPR011615p53, DNA-binding domain
IPR012346p53/RUNT-type transcription factor, DNA-binding domain superfamily
IPR024631Transcription factor p53, C-terminal, Drosophila

No MapMan annotations defined for this gene.
KeggID Description
K04451TP53, P53; tumor protein p53
K10148TP73; tumor protein p73
K10149TP63; tumor protein p63
No chloroplast target sequence found.