Gene: FBgn0035001 (Drosophila melanogaster)

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Gene Identifier
FBgn0035001
Transcript Identifier
FBtr0072366
Gene Type
Coding gene
Location
2R : 24393054-24401369 : negative

Family Information

Homologous gene family
HOM02SEM000001
(5917 genes in 26 species)
specific family

Descriptions

gene_descr
Sterile20-like kinase

Identifiers

Type Value
pidFBpp0072273
UniprotQ9W179
RefSeq_mRNANM_206213.3
EMBLAE013599

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
IDA, IMP
NAS
Genome Projectprotein phosphorylation
GO:0006468
IDA, IMP
NAS
Gene Ontologyprotein phosphorylation1 2 3 4
GO:0000132
IMP
Genome Projectestablishment of mitotic spindle orientation
GO:0000132
IMP
Gene Ontologyestablishment of mitotic spindle orientation3
GO:0000902
IMP
Genome Projectcell morphogenesis
GO:0000902
IMP
Gene Ontologycell morphogenesis3
GO:0007091
IMP
Genome Projectmetaphase/anaphase transition of mitotic cell cycle
GO:0007091
IMP
Gene Ontologymetaphase/anaphase transition of mitotic cell cycle3
GO:0007052
IMP
Genome Projectmitotic spindle organization
GO:0007052
IMP
Gene Ontologymitotic spindle organization3
GO:0030866
IMP
Genome Projectcortical actin cytoskeleton organization
GO:0030866
IMP
Gene Ontologycortical actin cytoskeleton organization3
GO:0010800
IMP
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010800
IMP
Gene Ontologypositive regulation of peptidyl-threonine phosphorylation5
GO:0032879
IMP
Genome Projectregulation of localization
GO:0032879
IMP
Gene Ontologyregulation of localization2
GO:0000281
IMP
Genome Projectmitotic cytokinesis
GO:0000281
IMP
Gene Ontologymitotic cytokinesis6
GO:0008283
IMP
Genome Projectcell proliferation
GO:0008283
IMP
Gene Ontologycell proliferation7
GO:0060446
IMP
Gene Ontologybranching involved in open tracheal system development8
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death ENSG00000065613
GO:1903391
IEA
PLAZA Integrative Orthologyregulation of adherens junction organization ENSG00000065613
GO:0031122
IEA
PLAZA Integrative Orthologycytoplasmic microtubule organization ENSG00000065613
GO:0030155
IEA
PLAZA Integrative Orthologyregulation of cell adhesion ENSG00000065613
GO:0072676
IEA
PLAZA Integrative Orthologylymphocyte migration ENSG00000072786
GO:0050900
IEA
PLAZA Integrative Orthologyleukocyte migration ENSG00000072786
GO:2000145
IEA
PLAZA Integrative Orthologyregulation of cell motility ENSG00000072786
GO:0097435
IEA
PLAZA Integrative Orthologysupramolecular fiber organization ENSG00000065613
GO:0045321
IEA
PLAZA Integrative Orthologyleukocyte activation ENSG00000072786
GO:0051674
IEA
PLAZA Integrative Orthologylocalization of cell ENSG00000072786
GO:0001775
IEA
PLAZA Integrative Orthologycell activation ENSG00000072786
GO:0048870
IEA
PLAZA Integrative Orthologycell motility ENSG00000072786
GO:0022610
IEA
PLAZA Integrative Orthologybiological adhesion ENSG00000065613
GO:0002275
IEA
PLAZA Integrative Orthologymyeloid cell activation involved in immune response ENSG00000072786
GO:0002274
IEA
PLAZA Integrative Orthologymyeloid leukocyte activation ENSG00000072786
GO:0007045
IEA
PLAZA Integrative Orthologycell-substrate adherens junction assembly ENSG00000065613
GO:0043299
IEA
PLAZA Integrative Orthologyleukocyte degranulation ENSG00000072786
GO:0007044
IEA
PLAZA Integrative Orthologycell-substrate junction assembly ENSG00000065613
GO:0007160
IEA
PLAZA Integrative Orthologycell-matrix adhesion ENSG00000065613
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus ENSG00000072786
GO:0032940
IEA
PLAZA Integrative Orthologysecretion by cell ENSG00000072786
GO:0016477
IEA
PLAZA Integrative Orthologycell migration ENSG00000072786
GO:0034329
IEA
PLAZA Integrative Orthologycell junction assembly ENSG00000065613
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport ENSG00000072786
GO:1901888
IEA
PLAZA Integrative Orthologyregulation of cell junction assembly ENSG00000065613
GO:0002263
IEA
PLAZA Integrative Orthologycell activation involved in immune response ENSG00000072786
GO:0051270
IEA
PLAZA Integrative Orthologyregulation of cellular component movement ENSG00000072786
GO:0007155
IEA
PLAZA Integrative Orthologycell adhesion ENSG00000065613
GO:0034330
IEA
PLAZA Integrative Orthologycell junction organization ENSG00000065613
GO:0036230
IEA
PLAZA Integrative Orthologygranulocyte activation ENSG00000072786
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion ENSG00000072786
GO:0034332
IEA
PLAZA Integrative Orthologyadherens junction organization ENSG00000065613
GO:0040012
IEA
PLAZA Integrative Orthologyregulation of locomotion ENSG00000072786
GO:0042119
IEA
PLAZA Integrative Orthologyneutrophil activation ENSG00000072786
GO:0090109
IEA
PLAZA Integrative Orthologyregulation of cell-substrate junction assembly ENSG00000065613
GO:2000401
IEA
PLAZA Integrative Orthologyregulation of lymphocyte migration ENSG00000072786
GO:0031589
IEA
PLAZA Integrative Orthologycell-substrate adhesion ENSG00000065613
GO:0030334
IEA
PLAZA Integrative Orthologyregulation of cell migration ENSG00000072786
GO:0034333
IEA
PLAZA Integrative Orthologyadherens junction assembly ENSG00000065613
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death ENSG00000065613
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component ENSG00000072786
GO:0001952
IEA
PLAZA Integrative Orthologyregulation of cell-matrix adhesion ENSG00000065613
GO:0051893
IEA
PLAZA Integrative Orthologyregulation of focal adhesion assembly ENSG00000065613
GO:0002446
IEA
PLAZA Integrative Orthologyneutrophil mediated immunity ENSG00000072786
GO:0002444
IEA
PLAZA Integrative Orthologymyeloid leukocyte mediated immunity ENSG00000072786
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000072786
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000072786
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process ENSG00000072786
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process ENSG00000065613
GO:0043312
IEA
PLAZA Integrative Orthologyneutrophil degranulation ENSG00000072786
GO:0046903
IEA
PLAZA Integrative Orthologysecretion ENSG00000072786
GO:0048041
IEA
PLAZA Integrative Orthologyfocal adhesion assembly ENSG00000065613
GO:0010810
IEA
PLAZA Integrative Orthologyregulation of cell-substrate adhesion ENSG00000065613
GO:0045055
IEA
PLAZA Integrative Orthologyregulated exocytosis ENSG00000072786
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis ENSG00000065613
GO:0008219
IEA
PLAZA Integrative Orthologycell death ENSG00000065613
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000072786
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000065613
GO:0002685
IEA
PLAZA Integrative Orthologyregulation of leukocyte migration ENSG00000072786
GO:0002443
IEA
PLAZA Integrative Orthologyleukocyte mediated immunity ENSG00000072786
GO:0002366
IEA
PLAZA Integrative Orthologyleukocyte activation involved in immune response ENSG00000072786
GO:0006887
IEA
PLAZA Integrative Orthologyexocytosis ENSG00000072786
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process ENSG00000072786
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death ENSG00000065613
GO:0002283
IEA
PLAZA Integrative Orthologyneutrophil activation involved in immune response ENSG00000072786
GO:0046777
IEA
PLAZA Integrative Orthologyprotein autophosphorylation ENSG00000072786
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000065613

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004674
IDA, IMP
Genome Projectprotein serine/threonine kinase activity
GO:0004674
IDA, IMP
Gene Ontologyprotein serine/threonine kinase activity2 3
GO:0005524
IEA
Genome ProjectATP binding
GO:0042803
IEA
PLAZA Integrative Orthologyprotein homodimerization activity ENSG00000072786
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000072786
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000072786
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000072786
GO:0045296
IEA
PLAZA Integrative Orthologycadherin binding ENSG00000065613
GO:0050839
IEA
PLAZA Integrative Orthologycell adhesion molecule binding ENSG00000065613

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990023
IDA
Genome Projectmitotic spindle midzone
GO:1990023
IDA
Gene Ontologymitotic spindle midzone3
GO:0032154
IDA
Genome Projectcleavage furrow
GO:0032154
IDA
Gene Ontologycleavage furrow3
GO:0005938
IDA
Genome Projectcell cortex
GO:0005938
IDA
Gene Ontologycell cortex3
GO:0098805
IEA
PLAZA Integrative Orthologywhole membrane ENSG00000072786
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system ENSG00000072786
GO:0012506
IEA
PLAZA Integrative Orthologyvesicle membrane ENSG00000072786
GO:0048471
IEA
PLAZA Integrative Orthologyperinuclear region of cytoplasm ENSG00000065613
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000072786
GO:0031090
IEA
PLAZA Integrative Orthologyorganelle membrane ENSG00000072786
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000072786
GO:0035579
IEA
PLAZA Integrative Orthologyspecific granule membrane ENSG00000072786
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle ENSG00000072786
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle ENSG00000072786
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000072786
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000072786
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000072786
GO:0098588
IEA
PLAZA Integrative Orthologybounding membrane of organelle ENSG00000072786
GO:0030659
IEA
PLAZA Integrative Orthologycytoplasmic vesicle membrane ENSG00000072786
GO:0030141
IEA
PLAZA Integrative Orthologysecretory granule ENSG00000072786
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000072786
GO:0042581
IEA
PLAZA Integrative Orthologyspecific granule ENSG00000072786
GO:0099503
IEA
PLAZA Integrative Orthologysecretory vesicle ENSG00000072786
GO:0030667
IEA
PLAZA Integrative Orthologysecretory granule membrane ENSG00000072786
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle ENSG00000072786
GO:0044433
IEA
PLAZA Integrative Orthologycytoplasmic vesicle part ENSG00000072786
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000072786

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain superfamily
IPR017441Protein kinase, ATP binding site
IPR022165Polo kinase kinase

No MapMan annotations defined for this gene.
KeggID Description
K08836SLK; STE20-like kinase
K08837STK10, LOK; serine/threonine kinase 10
No chloroplast target sequence found.