Gene: FBgn0031187 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0031187
Transcript Identifier
FBtr0339507
Gene Type
Coding gene
Location
X : 22463903-22468184 : positive

Family Information

Homologous gene family
HOM02SEM000130
(193 genes in 26 species)
specific family

Descriptions

Identifiers

Type Value
pidFBpp0308590
UniprotC6SUY9
UniprotX2JG37
RefSeq_mRNANM_001298599.1
EMBLAE014298
EMBLBT088981

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1900425
IMP
Genome Projectnegative regulation of defense response to bacterium
GO:1900425
IMP
Gene Ontologynegative regulation of defense response to bacterium1
GO:0045824
IMP
Genome Projectnegative regulation of innate immune response
GO:0045824
IMP
Gene Ontologynegative regulation of innate immune response1
GO:0071108
IDA
Genome Projectprotein K48-linked deubiquitination
GO:0071108
IDA
Gene Ontologyprotein K48-linked deubiquitination1
GO:1901800
IMP
Genome Projectpositive regulation of proteasomal protein catabolic process
GO:1901800
IMP
Gene Ontologypositive regulation of proteasomal protein catabolic process1
GO:0002785
IMP
Genome Projectnegative regulation of antimicrobial peptide production
GO:0002785
IMP
Gene Ontologynegative regulation of antimicrobial peptide production1
GO:0016579
IMP
ISS
Genome Projectprotein deubiquitination
GO:0016579
IMP
ISS
Gene Ontologyprotein deubiquitination2
GO:0006511
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0050821
IEA
PLAZA Integrative Orthologyprotein stabilization ENSG00000036672
GO:0042493
IEA
PLAZA Integrative Orthologyresponse to drug YDR069C
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process ENSG00000036672
GO:0031647
IEA
PLAZA Integrative Orthologyregulation of protein stability ENSG00000036672
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000036672
GO:0006900
IEA
PLAZA Integrative Orthologyvesicle budding from membrane YDR069C
GO:0000375
IEA
PLAZA Integrative OrthologyRNA splicing, via transesterification reactions ENSG00000164663
GO:0006357
IEA
PLAZA Integrative Orthologyregulation of transcription by RNA polymerase II ENSG00000036672
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle ENSG00000140455
GO:0022411
IEA
PLAZA Integrative Orthologycellular component disassembly YDR069C
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization YDR069C
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated ENSG00000036672
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process YDR069C
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated ENSG00000036672
GO:0061024
IEA
PLAZA Integrative Orthologymembrane organization YDR069C
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process YDR069C
GO:0032984
IEA
PLAZA Integrative Orthologyprotein-containing complex disassembly YDR069C
GO:0051503
IEA
PLAZA Integrative Orthologyadenine nucleotide transport YDR069C
GO:0035616
IEA
PLAZA Integrative Orthologyhistone H2B conserved C-terminal lysine deubiquitination ENSG00000164663
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process YDR069C
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process ENSG00000036672
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress ENSG00000140455
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process YDR069C
GO:0000122
IEA
PLAZA Integrative Orthologynegative regulation of transcription by RNA polymerase II ENSG00000036672
GO:0006862
IEA
PLAZA Integrative Orthologynucleotide transport YDR069C
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription ENSG00000036672
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription ENSG00000036672
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process YDR069C
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process YDR069C
GO:0007032
IEA
PLAZA Integrative Orthologyendosome organization YDR069C
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000036672
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YDR069C
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000036672
GO:0010467
IEA
PLAZA Integrative Orthologygene expression ENSG00000036672
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression ENSG00000036672
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YDR069C
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process YDR069C
GO:0043162
IEA
PLAZA Integrative Orthologyubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway YDR069C
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression ENSG00000036672
GO:0007346
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle ENSG00000036672
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process YDR069C
GO:0006897
IEA
PLAZA Integrative Orthologyendocytosis YDR069C
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process YDR069C
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process YDR069C
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical YDR069C
GO:0006259
IEA
PLAZA Integrative OrthologyDNA metabolic process YDR069C
GO:1904669
IEA
PLAZA Integrative OrthologyATP export YDR069C
GO:0035871
IEA
PLAZA Integrative Orthologyprotein K11-linked deubiquitination SPBC18H10.08c
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process ENSG00000036672
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process YDR069C
GO:0016578
IEA
PLAZA Integrative Orthologyhistone deubiquitination ENSG00000140455
GO:0015865
IEA
PLAZA Integrative Orthologypurine nucleotide transport YDR069C
GO:0015867
IEA
PLAZA Integrative OrthologyATP transport YDR069C
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle ENSG00000036672
GO:0015748
IEA
PLAZA Integrative Orthologyorganophosphate ester transport YDR069C
GO:0015868
IEA
PLAZA Integrative Orthologypurine ribonucleotide transport YDR069C
GO:0016570
IEA
PLAZA Integrative Orthologyhistone modification ENSG00000140455
GO:0098657
IEA
PLAZA Integrative Orthologyimport into cell YDR069C
GO:0016050
IEA
PLAZA Integrative Orthologyvesicle organization YDR069C
GO:0000377
IEA
PLAZA Integrative OrthologyRNA splicing, via transesterification reactions with bulged adenosine as nucleophile ENSG00000164663
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process YDR069C
GO:0006366
IEA
PLAZA Integrative Orthologytranscription by RNA polymerase II ENSG00000036672
GO:1901264
IEA
PLAZA Integrative Orthologycarbohydrate derivative transport YDR069C
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process ENSG00000036672
GO:0008380
IEA
PLAZA Integrative OrthologyRNA splicing ENSG00000164663
GO:0016569
IEA
PLAZA Integrative Orthologycovalent chromatin modification ENSG00000140455
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport YDR069C
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process ENSG00000036672
GO:0015931
IEA
PLAZA Integrative Orthologynucleobase-containing compound transport YDR069C
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process YDR069C
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process ENSG00000036672
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus ENSG00000140455
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization ENSG00000140455
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process ENSG00000036672
GO:0006397
IEA
PLAZA Integrative OrthologymRNA processing ENSG00000164663
GO:0006275
IEA
PLAZA Integrative Orthologyregulation of DNA replication YDR069C
GO:0006396
IEA
PLAZA Integrative OrthologyRNA processing ENSG00000164663
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport YDR069C
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YDR069C
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis YDR069C
GO:0010995
IEA
PLAZA Integrative Orthologyfree ubiquitin chain depolymerization YDR069C
GO:0010992
IEA
PLAZA Integrative Orthologyubiquitin recycling YDR069C
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000036672
GO:0016071
IEA
PLAZA Integrative OrthologymRNA metabolic process ENSG00000164663
GO:0016192
IEA
PLAZA Integrative Orthologyvesicle-mediated transport YDR069C
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process ENSG00000036672
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process YDR069C
GO:0000398
IEA
PLAZA Integrative OrthologymRNA splicing, via spliceosome ENSG00000164663
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle ENSG00000036672
GO:0006820
IEA
PLAZA Integrative Orthologyanion transport YDR069C
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle ENSG00000036672
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process ENSG00000036672
GO:0006260
IEA
PLAZA Integrative OrthologyDNA replication YDR069C
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000036672
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process ENSG00000036672
GO:0015893
IEA
PLAZA Integrative Orthologydrug transport YDR069C
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process YDR069C
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process YDR069C
GO:0015711
IEA
PLAZA Integrative Orthologyorganic anion transport YDR069C
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription ENSG00000036672
GO:0070676
IEA
PLAZA Integrative Orthologyintralumenal vesicle formation YDR069C
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process ENSG00000036672
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process ENSG00000036672
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process YDR069C
GO:0045931
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle ENSG00000036672
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process ENSG00000036672
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus ENSG00000140455
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process ENSG00000036672
GO:0051261
IEA
PLAZA Integrative Orthologyprotein depolymerization YDR069C
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality YDR069C
GO:0010256
IEA
PLAZA Integrative Orthologyendomembrane system organization YDR069C
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process YDR069C
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process ENSG00000036672
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated ENSG00000036672
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process ENSG00000036672
GO:0043624
IEA
PLAZA Integrative Orthologycellular protein complex disassembly YDR069C
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization ENSG00000140455
GO:0046618
IEA
PLAZA Integrative Orthologydrug export YDR069C
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair ENSG00000140455
GO:0051926
IMP
Gene Ontologynegative regulation of calcium ion transport3
GO:0045805
IMP
Gene Ontologypositive regulation of eclosion4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1
GO:0070628
IPI
Genome Projectproteasome binding
GO:0070628
IPI
Gene Ontologyproteasome binding1
GO:1990380
IDA
Genome ProjectLys48-specific deubiquitinase activity
GO:1990380
IDA
Gene OntologyLys48-specific deubiquitinase activity1
GO:0004843
ISS
Genome Projectthiol-dependent ubiquitin-specific protease activity
GO:0004843
ISS
Gene Ontologythiol-dependent ubiquitin-specific protease activity
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000036672
GO:0044389
IEA
PLAZA Integrative Orthologyubiquitin-like protein ligase binding ENSG00000036672
GO:0004175
IEA
PLAZA Integrative Orthologyendopeptidase activity ENSG00000036672
GO:0019784
IEA
PLAZA Integrative OrthologyNEDD8-specific protease activity ENSG00000143258
GO:0030332
IEA
PLAZA Integrative Orthologycyclin binding ENSG00000036672
GO:0004197
IEA
PLAZA Integrative Orthologycysteine-type endopeptidase activity ENSG00000036672
GO:0042393
IEA
PLAZA Integrative Orthologyhistone binding ENSG00000140455
GO:0031625
IEA
PLAZA Integrative Orthologyubiquitin protein ligase binding ENSG00000036672

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005575
ND
Genome Projectcellular_component
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system SPBC18H10.08c
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000143258
GO:0005935
IEA
PLAZA Integrative Orthologycellular bud neck YER144C
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000036672
GO:0005933
IEA
PLAZA Integrative Orthologycellular bud YER144C
GO:0000131
IEA
PLAZA Integrative Orthologyincipient cellular bud site YER144C
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part ENSG00000140455
GO:0044424
IEA
PLAZA Integrative Orthologyintracellular part SPBC18H10.08c
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part ENSG00000036672
GO:0070938
IEA
PLAZA Integrative Orthologycontractile ring ENSG00000140455
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000036672
GO:0097708
IEA
PLAZA Integrative Orthologyintracellular vesicle SPBC18H10.08c
GO:1990904
IEA
PLAZA Integrative Orthologyribonucleoprotein complex ENSG00000140455
GO:0031410
IEA
PLAZA Integrative Orthologycytoplasmic vesicle SPBC18H10.08c
GO:0005768
IEA
PLAZA Integrative Orthologyendosome SPBC18H10.08c
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000036672
GO:1905368
IEA
PLAZA Integrative Orthologypeptidase complex YDR069C
GO:1902494
IEA
PLAZA Integrative Orthologycatalytic complex YDR069C
GO:1905369
IEA
PLAZA Integrative Orthologyendopeptidase complex YDR069C
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex YDR069C
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin ENSG00000140455
GO:0000785
IEA
PLAZA Integrative Orthologychromatin ENSG00000140455
GO:0090543
IEA
PLAZA Integrative OrthologyFlemming body ENSG00000140455
GO:0005829
IEA
PLAZA Integrative Orthologycytosol YDR069C
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery ENSG00000143258
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion SPBC19C2.04c
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPBC18H10.08c
GO:0005622
IEA
PLAZA Integrative Orthologyintracellular SPBC18H10.08c
GO:0044464
IEA
PLAZA Integrative Orthologycell part SPBC18H10.08c
GO:0036464
IEA
PLAZA Integrative Orthologycytoplasmic ribonucleoprotein granule ENSG00000140455
GO:0035770
IEA
PLAZA Integrative Orthologyribonucleoprotein granule ENSG00000140455
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000036672
GO:0005694
IEA
PLAZA Integrative Orthologychromosome ENSG00000140455
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part ENSG00000140455
GO:0032153
IEA
PLAZA Integrative Orthologycell division site SPBC18H10.08c
GO:0030496
IEA
PLAZA Integrative Orthologymidbody ENSG00000140455
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle SPBC18H10.08c
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000036672
GO:0005634
IEA
PLAZA Integrative Orthologynucleus ENSG00000036672
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane ENSG00000143258
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part ENSG00000036672
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPBC18H10.08c
GO:0000502
IEA
PLAZA Integrative Orthologyproteasome complex YDR069C
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome ENSG00000140455
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle ENSG00000140455
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000036672
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle SPBC19C2.04c
GO:0030427
IEA
PLAZA Integrative Orthologysite of polarized growth YER144C
GO:0005623
IEA
PLAZA Integrative Orthologycell SPBC18H10.08c
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle SPBC18H10.08c
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle ENSG00000140455
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle SPBC18H10.08c
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle SPBC18H10.08c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001394Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR018200Ubiquitin specific protease, conserved site
IPR028889Ubiquitin specific protease domain

No MapMan annotations defined for this gene.
KeggID Description
K11833USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
No chloroplast target sequence found.