Gene: FBgn0005674 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0005674
Transcript Identifier
FBtr0084511
Gene Type
Coding gene
Location
3R : 23952290-23958285 : negative

Family Information

Homologous gene family
HOM02SEM000189
(145 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000393
(84 genes in 26 species)
specific family

Descriptions

gene_descr
Glutamyl-prolyl-tRNA synthetase

Identifiers

Type Value
pidFBpp0083898
UniprotP28668
RefSeq_mRNANM_079747.3
EMBLAE014297
EMBLAY058703
EMBLBT001645
EMBLM74104
EMBLU59923

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006433
TAS, IEA
Genome Projectprolyl-tRNA aminoacylation
GO:0006433
TAS
Gene Ontologyprolyl-tRNA aminoacylation1
GO:0006424
TAS, IEA
Genome Projectglutamyl-tRNA aminoacylation
GO:0006424
TAS
Gene Ontologyglutamyl-tRNA aminoacylation1
GO:0071346
IEA
PLAZA Integrative Orthologycellular response to interferon-gamma ENSG00000136628
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process AT5G52520
GO:0071345
IEA
PLAZA Integrative Orthologycellular response to cytokine stimulus ENSG00000136628
GO:0015979
IEA
PLAZA Integrative Orthologyphotosynthesis AT5G52520
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process ENSG00000136628
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response ENSG00000136628
GO:0051234
IEA
PLAZA Integrative Orthologyestablishment of localization ENSG00000136628
GO:0010608
IEA
PLAZA Integrative Orthologyposttranscriptional regulation of gene expression ENSG00000136628
GO:0006869
IEA
PLAZA Integrative Orthologylipid transport ENSG00000136628
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT5G52520
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT5G52520
GO:0048229
IEA
PLAZA Integrative Orthologygametophyte development AT5G52520
GO:0034249
IEA
PLAZA Integrative Orthologynegative regulation of cellular amide metabolic process ENSG00000136628
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT5G52520
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus ENSG00000136628
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT5G52520
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process ENSG00000136628
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization ENSG00000136628
GO:0034248
IEA
PLAZA Integrative Orthologyregulation of cellular amide metabolic process ENSG00000136628
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process ENSG00000136628
GO:0015849
IEA
PLAZA Integrative Orthologyorganic acid transport ENSG00000136628
GO:0048467
IEA
PLAZA Integrative Orthologygynoecium development AT5G52520
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT5G52520
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT5G52520
GO:0044539
IEA
PLAZA Integrative Orthologylong-chain fatty acid import ENSG00000136628
GO:0034097
IEA
PLAZA Integrative Orthologyresponse to cytokine ENSG00000136628
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis ENSG00000136628
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression ENSG00000136628
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization ENSG00000136628
GO:0010109
IEA
PLAZA Integrative Orthologyregulation of photosynthesis AT5G52520
GO:0048731
IEA
PLAZA Integrative Orthologysystem development AT5G52520
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression ENSG00000136628
GO:0051179
IEA
PLAZA Integrative Orthologylocalization ENSG00000136628
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process ENSG00000136628
GO:0006810
IEA
PLAZA Integrative Orthologytransport ENSG00000136628
GO:0046942
IEA
PLAZA Integrative Orthologycarboxylic acid transport ENSG00000136628
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical ENSG00000136628
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT5G52520
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus ENSG00000136628
GO:0017148
IEA
PLAZA Integrative Orthologynegative regulation of translation ENSG00000136628
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT5G52520
GO:0015908
IEA
PLAZA Integrative Orthologyfatty acid transport ENSG00000136628
GO:0015909
IEA
PLAZA Integrative Orthologylong-chain fatty acid transport ENSG00000136628
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000136628
GO:0048440
IEA
PLAZA Integrative Orthologycarpel development AT5G52520
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT5G52520
GO:0051171
IEA
PLAZA Integrative Orthologyregulation of nitrogen compound metabolic process ENSG00000136628
GO:0048437
IEA
PLAZA Integrative Orthologyfloral organ development AT5G52520
GO:0048316
IEA
PLAZA Integrative Orthologyseed development AT5G52520
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process ENSG00000136628
GO:0048438
IEA
PLAZA Integrative Orthologyfloral whorl development AT5G52520
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000136628
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process ENSG00000136628
GO:0031323
IEA
PLAZA Integrative Orthologyregulation of cellular metabolic process AT5G52520
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport ENSG00000136628
GO:0080090
IEA
PLAZA Integrative Orthologyregulation of primary metabolic process ENSG00000136628
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process ENSG00000136628
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus ENSG00000136628
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process ENSG00000136628
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress ENSG00000136628
GO:0048827
IEA
PLAZA Integrative Orthologyphyllome development AT5G52520
GO:0006952
IEA
PLAZA Integrative Orthologydefense response ENSG00000136628
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT5G52520
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization ENSG00000136628
GO:0060255
IEA
PLAZA Integrative Orthologyregulation of macromolecule metabolic process ENSG00000136628
GO:0032269
IEA
PLAZA Integrative Orthologynegative regulation of cellular protein metabolic process ENSG00000136628
GO:0010876
IEA
PLAZA Integrative Orthologylipid localization ENSG00000136628
GO:0032268
IEA
PLAZA Integrative Orthologyregulation of cellular protein metabolic process ENSG00000136628
GO:0019222
IEA
PLAZA Integrative Orthologyregulation of metabolic process AT5G52520
GO:0099402
IEA
PLAZA Integrative Orthologyplant organ development AT5G52520
GO:0071310
IEA
PLAZA Integrative Orthologycellular response to organic substance ENSG00000136628
GO:0006811
IEA
PLAZA Integrative Orthologyion transport ENSG00000136628
GO:0006417
IEA
PLAZA Integrative Orthologyregulation of translation ENSG00000136628
GO:0006820
IEA
PLAZA Integrative Orthologyanion transport ENSG00000136628
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process ENSG00000136628
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process ENSG00000136628
GO:0015711
IEA
PLAZA Integrative Orthologyorganic anion transport ENSG00000136628
GO:0015718
IEA
PLAZA Integrative Orthologymonocarboxylic acid transport ENSG00000136628
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000136628
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process ENSG00000136628
GO:0035670
IEA
PLAZA Integrative Orthologyplant-type ovary development AT5G52520
GO:0034341
IEA
PLAZA Integrative Orthologyresponse to interferon-gamma ENSG00000136628
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly ENSG00000136628
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance ENSG00000136628
GO:0010154
IEA
PLAZA Integrative Orthologyfruit development AT5G52520
GO:0051248
IEA
PLAZA Integrative Orthologynegative regulation of protein metabolic process ENSG00000136628
GO:0065007
IEA
PLAZA Integrative Orthologybiological regulation AT5G52520
GO:0048481
IEA
PLAZA Integrative Orthologyplant ovule development AT5G52520
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process ENSG00000136628
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process ENSG00000136628
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT5G52520
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000136628
GO:0050794
IEA
PLAZA Integrative Orthologyregulation of cellular process AT5G52520
GO:0051246
IEA
PLAZA Integrative Orthologyregulation of protein metabolic process ENSG00000136628
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT5G52520
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process ENSG00000136628
GO:0009553
IEA
PLAZA Integrative Orthologyembryo sac development AT5G52520
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT5G52520

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004818
TAS, IEA
Genome Projectglutamate-tRNA ligase activity
GO:0004818
TAS
Gene Ontologyglutamate-tRNA ligase activity1
GO:0004827
TAS, IEA
Genome Projectproline-tRNA ligase activity
GO:0004827
TAS
Gene Ontologyproline-tRNA ligase activity1
GO:0005524
IEA
Genome ProjectATP binding
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding ENSG00000136628
GO:0042803
IEA
PLAZA Integrative Orthologyprotein homodimerization activity ENSG00000136628
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000136628
GO:0035613
IEA
PLAZA Integrative OrthologyRNA stem-loop binding ENSG00000136628
GO:0043169
IEA
PLAZA Integrative Orthologycation binding ENSG00000136628
GO:0008270
IEA
PLAZA Integrative Orthologyzinc ion binding ENSG00000136628
GO:0003676
IEA
PLAZA Integrative Orthologynucleic acid binding YGL245W
GO:0051020
IEA
PLAZA Integrative OrthologyGTPase binding ENSG00000136628
GO:0046914
IEA
PLAZA Integrative Orthologytransition metal ion binding ENSG00000136628
GO:0046872
IEA
PLAZA Integrative Orthologymetal ion binding ENSG00000136628
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding SPAC17A5.15c
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity ENSG00000136628
GO:0003729
IEA
PLAZA Integrative OrthologymRNA binding YGL245W
GO:0003723
IEA
PLAZA Integrative OrthologyRNA binding YGL245W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005737
TAS
Gene Ontologycytoplasm1
GO:0017101
IDA
Genome Projectaminoacyl-tRNA synthetase multienzyme complex
GO:0017101
IDA
Gene Ontologyaminoacyl-tRNA synthetase multienzyme complex2
GO:0016020
IEA
PLAZA Integrative Orthologymembrane AT3G62120
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part AT5G52520
GO:0055044
IEA
PLAZA Integrative Orthologysymplast AT3G62120
GO:1990904
IEA
PLAZA Integrative Orthologyribonucleoprotein complex YHR020W
GO:0009570
IEA
PLAZA Integrative Orthologychloroplast stroma AT5G52520
GO:0030054
IEA
PLAZA Integrative Orthologycell junction AT3G62120
GO:0097452
IEA
PLAZA Integrative OrthologyGAIT complex ENSG00000136628
GO:0005840
IEA
PLAZA Integrative Orthologyribosome YHR020W
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC17A5.15c
GO:0009506
IEA
PLAZA Integrative Orthologyplasmodesma AT3G62120
GO:0009507
IEA
PLAZA Integrative Orthologychloroplast AT5G52520
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion AT5G52520
GO:0010494
IEA
PLAZA Integrative Orthologycytoplasmic stress granule YGL245W
GO:0036464
IEA
PLAZA Integrative Orthologycytoplasmic ribonucleoprotein granule YGL245W
GO:0035770
IEA
PLAZA Integrative Orthologyribonucleoprotein granule YGL245W
GO:0009536
IEA
PLAZA Integrative Orthologyplastid AT5G52520
GO:0009532
IEA
PLAZA Integrative Orthologyplastid stroma AT5G52520
GO:0005911
IEA
PLAZA Integrative Orthologycell-cell junction AT3G62120
GO:0005634
IEA
PLAZA Integrative Orthologynucleus SPAC17A5.15c
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part AT5G52520
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC17A5.15c
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle YHR020W
GO:0017102
IEA
PLAZA Integrative Orthologymethionyl glutamyl tRNA synthetase complex YGL245W
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle SPAC17A5.15c
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle SPAC17A5.15c
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle YHR020W
GO:0044435
IEA
PLAZA Integrative Orthologyplastid part AT5G52520
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle SPAC17A5.15c
GO:0044434
IEA
PLAZA Integrative Orthologychloroplast part AT5G52520
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle SPAC17A5.15c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000738WHEP-TRS domain
IPR000924Glutamyl/glutaminyl-tRNA synthetase
IPR001412Aminoacyl-tRNA synthetase, class I, conserved site
IPR002314Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
IPR004046Glutathione S-transferase, C-terminal
IPR004154Anticodon-binding
IPR004499Proline-tRNA ligase, class IIa, archaeal-type
IPR004526Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic
IPR006195Aminoacyl-tRNA synthetase, class II
IPR009068S15/NS1, RNA-binding
IPR010987Glutathione S-transferase, C-terminal-like
IPR011035Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily
IPR014729Rossmann-like alpha/beta/alpha sandwich fold
IPR016061Proline-tRNA ligase, class II, C-terminal
IPR017449Prolyl-tRNA synthetase, class II
IPR020056Ribosomal protein L25/Gln-tRNA synthetase, N-terminal
IPR020058Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
IPR020059Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
IPR020061Glutamine-tRNA ligase, alpha-bundle domain superfamily
IPR033721Prolyl-tRNA synthetase, catalytic domain

No MapMan annotations defined for this gene.
KeggID Description
K03027RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
K14163EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
No chloroplast target sequence found.