Gene: FBgn0002989 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0002989
Transcript Identifier
FBtr0077673
Gene Type
Coding gene
Location
2L : 2990067-2992709 : negative

Family Information

Homologous gene family
HOM02SEM000010
(859 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM000020
(548 genes in 26 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
okra

Identifiers

Type Value
pidFBpp0077357
UniprotO76460
RefSeq_mRNANM_057313.5
EMBLAE014134
EMBLAF069779
EMBLAF069780
EMBLAY069599
EMBLFJ219215
EMBLFJ219218
EMBLFJ219219
EMBLFJ219220
EMBLFJ219221
EMBLFJ219222
EMBLFJ219223
EMBLFJ219224
EMBLFJ219225
EMBLFJ219226
EMBLFJ219227
EMBLFJ219228
EMBLFJ219229
EMBLFJ219230
EMBLFJ219231
EMBLFJ219232
EMBLFJ219233
EMBLFJ219234
EMBLFJ219235
EMBLFJ219236
EMBLFJ219237
EMBLFJ219238
EMBLFJ219239
EMBLFJ219240
EMBLFJ219241
EMBLFJ219242
EMBLFJ219243
EMBLFJ219244
EMBLFJ219245
EMBLFJ219246
EMBLFJ219247
EMBLY10229

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048477
IMP, IGI
TAS
Genome Projectoogenesis
GO:0048477
IGI
TAS
Gene Ontologyoogenesis1 2 3
GO:0030716
IMP
Genome Projectoocyte fate determination
GO:0030716
IMP
Gene Ontologyoocyte fate determination4
GO:0007131
IMP
TAS
Genome Projectreciprocal meiotic recombination
GO:0007131
IMP
TAS
Gene Ontologyreciprocal meiotic recombination2 4 5
GO:0045003
IMP
Genome Projectdouble-strand break repair via synthesis-dependent strand annealing
GO:0045003
IMP
Gene Ontologydouble-strand break repair via synthesis-dependent strand annealing6
GO:0000724
IMP
Genome Projectdouble-strand break repair via homologous recombination
GO:0000724
IMP
Gene Ontologydouble-strand break repair via homologous recombination7
GO:0006338
IMP
Genome Projectchromatin remodeling
GO:0006338
IMP
Gene Ontologychromatin remodeling7
GO:0010212
IMP
Genome Projectresponse to ionizing radiation
GO:0010212
IMP
Gene Ontologyresponse to ionizing radiation8 9
GO:0006302
IMP
TAS
Genome Projectdouble-strand break repair
GO:0006302
IMP
TAS
Gene Ontologydouble-strand break repair4 8 10
GO:0030261
TAS
Genome Projectchromosome condensation
GO:0030261
TAS
Gene Ontologychromosome condensation2
GO:0006281
NAS
Genome ProjectDNA repair
GO:0006281
NAS
Gene OntologyDNA repair2
GO:0000711
IMP
Genome Projectmeiotic DNA repair synthesis
GO:0000711
IMP
Gene Ontologymeiotic DNA repair synthesis11
GO:0043150
IMP
Genome ProjectDNA synthesis involved in double-strand break repair via homologous recombination
GO:0043150
IMP
Gene OntologyDNA synthesis involved in double-strand break repair via homologous recombination11
GO:0006417
TAS
Genome Projectregulation of translation
GO:0006417
TAS
Gene Ontologyregulation of translation12
GO:0008298
TAS
Genome Projectintracellular mRNA localization
GO:0008298
TAS
Gene Ontologyintracellular mRNA localization12
GO:0006310
ISS
Genome ProjectDNA recombination
GO:0006310
ISS
Gene OntologyDNA recombination8
GO:0046843
IMP
Genome Projectdorsal appendage formation
GO:0046843
Gene Ontologydorsal appendage formation1
GO:0010605
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule metabolic process SPAC15A10.03c
GO:0045002
IEA
PLAZA Integrative Orthologydouble-strand break repair via single-strand annealing YGL163C
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process YGL163C
GO:1900368
IEA
PLAZA Integrative Orthologyregulation of RNA interference AT3G24340
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated SPAC15A10.03c
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated SPAC15A10.03c
GO:0010035
IEA
PLAZA Integrative Orthologyresponse to inorganic substance AT3G19210
GO:0071478
IEA
PLAZA Integrative Orthologycellular response to radiation AT3G19210
GO:0097549
IEA
PLAZA Integrative Orthologychromatin organization involved in negative regulation of transcription SPAC15A10.03c
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process SPAC15A10.03c
GO:0010038
IEA
PLAZA Integrative Orthologyresponse to metal ion AT3G19210
GO:0034401
IEA
PLAZA Integrative Orthologychromatin organization involved in regulation of transcription SPAC15A10.03c
GO:0032069
IEA
PLAZA Integrative Orthologyregulation of nuclease activity YGL163C
GO:0071479
IEA
PLAZA Integrative Orthologycellular response to ionizing radiation AT3G19210
GO:0032508
IEA
PLAZA Integrative OrthologyDNA duplex unwinding YBR073W
GO:0051345
IEA
PLAZA Integrative Orthologypositive regulation of hydrolase activity YGL163C
GO:1903507
IEA
PLAZA Integrative Orthologynegative regulation of nucleic acid-templated transcription SPAC15A10.03c
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription SPAC15A10.03c
GO:0006342
IEA
PLAZA Integrative Orthologychromatin silencing SPAC15A10.03c
GO:0032075
IEA
PLAZA Integrative Orthologypositive regulation of nuclease activity YGL163C
GO:0032077
IEA
PLAZA Integrative Orthologypositive regulation of deoxyribonuclease activity YGL163C
GO:0032071
IEA
PLAZA Integrative Orthologyregulation of endodeoxyribonuclease activity YGL163C
GO:0044419
IEA
PLAZA Integrative Orthologyinterspecies interaction between organisms AT3G19210
GO:0032070
IEA
PLAZA Integrative Orthologyregulation of deoxyribonuclease activity YGL163C
GO:0051336
IEA
PLAZA Integrative Orthologyregulation of hydrolase activity YGL163C
GO:0032079
IEA
PLAZA Integrative Orthologypositive regulation of endodeoxyribonuclease activity YGL163C
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus AT3G19210
GO:0016441
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing AT3G24340
GO:0051054
IEA
PLAZA Integrative Orthologypositive regulation of DNA metabolic process YGL163C
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process YGL163C
GO:0061806
IEA
PLAZA Integrative Orthologyregulation of DNA recombination at centromere SPAC15A10.03c
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function YGL163C
GO:0010629
IEA
PLAZA Integrative Orthologynegative regulation of gene expression SPAC15A10.03c
GO:0044403
IEA
PLAZA Integrative Orthologysymbiont process AT3G19210
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical AT3G19210
GO:0035194
IEA
PLAZA Integrative Orthologyposttranscriptional gene silencing by RNA AT3G24340
GO:0007062
IEA
PLAZA Integrative Orthologysister chromatid cohesion ENSG00000186871
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process SPAC15A10.03c
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus AT3G19210
GO:0010332
IEA
PLAZA Integrative Orthologyresponse to gamma radiation AT3G19210
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation YBR073W
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus AT3G19210
GO:0060968
IEA
PLAZA Integrative Orthologyregulation of gene silencing AT3G24340
GO:0000018
IEA
PLAZA Integrative Orthologyregulation of DNA recombination SPAC15A10.03c
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process YGL163C
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation YBR073W
GO:0060966
IEA
PLAZA Integrative Orthologyregulation of gene silencing by RNA AT3G24340
GO:0051052
IEA
PLAZA Integrative Orthologyregulation of DNA metabolic process SPAC15A10.03c
GO:0051172
IEA
PLAZA Integrative Orthologynegative regulation of nitrogen compound metabolic process SPAC15A10.03c
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation YBR073W
GO:0031324
IEA
PLAZA Integrative Orthologynegative regulation of cellular metabolic process SPAC15A10.03c
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process YGL163C
GO:0031047
IEA
PLAZA Integrative Orthologygene silencing by RNA AT3G24340
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process SPAC15A10.03c
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process SPAC15A10.03c
GO:0006312
IEA
PLAZA Integrative Orthologymitotic recombination YGL163C
GO:0040029
IEA
PLAZA Integrative Orthologyregulation of gene expression, epigenetic SPAC15A10.03c
GO:0000722
IEA
PLAZA Integrative Orthologytelomere maintenance via recombination YGL163C
GO:0000723
IEA
PLAZA Integrative Orthologytelomere maintenance YGL163C
GO:0006311
IEA
PLAZA Integrative Orthologymeiotic gene conversion SPAC15A10.03c
GO:0000726
IEA
PLAZA Integrative Orthologynon-recombinational repair YGL163C
GO:0061983
IEA
PLAZA Integrative Orthologymeiosis II cell cycle process YBR073W
GO:0016458
IEA
PLAZA Integrative Orthologygene silencing SPAC15A10.03c
GO:0051701
IEA
PLAZA Integrative Orthologyinteraction with host AT3G19210
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process SPAC15A10.03c
GO:0070192
IEA
PLAZA Integrative Orthologychromosome organization involved in meiotic cell cycle YBR073W
GO:0060148
IEA
PLAZA Integrative Orthologypositive regulation of posttranscriptional gene silencing AT3G24340
GO:0060147
IEA
PLAZA Integrative Orthologyregulation of posttranscriptional gene silencing AT3G24340
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process SPAC15A10.03c
GO:0009892
IEA
PLAZA Integrative Orthologynegative regulation of metabolic process SPAC15A10.03c
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process YGL163C
GO:0030491
IEA
PLAZA Integrative Orthologyheteroduplex formation YBR073W
GO:0032392
IEA
PLAZA Integrative OrthologyDNA geometric change YBR073W
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process SPAC15A10.03c
GO:0016246
IEA
PLAZA Integrative OrthologyRNA interference AT3G24340
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription SPAC15A10.03c
GO:0071248
IEA
PLAZA Integrative Orthologycellular response to metal ion AT3G19210
GO:0035822
IEA
PLAZA Integrative Orthologygene conversion SPAC15A10.03c
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process SPAC15A10.03c
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity YGL163C
GO:0045144
IEA
PLAZA Integrative Orthologymeiotic sister chromatid segregation YBR073W
GO:0051253
IEA
PLAZA Integrative Orthologynegative regulation of RNA metabolic process SPAC15A10.03c
GO:0071480
IEA
PLAZA Integrative Orthologycellular response to gamma radiation AT3G19210
GO:0071241
IEA
PLAZA Integrative Orthologycellular response to inorganic substance AT3G19210
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function YGL163C
GO:0045934
IEA
PLAZA Integrative Orthologynegative regulation of nucleobase-containing compound metabolic process SPAC15A10.03c
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process SPAC15A10.03c
GO:0045935
IEA
PLAZA Integrative Orthologypositive regulation of nucleobase-containing compound metabolic process YGL163C
GO:0045814
IEA
PLAZA Integrative Orthologynegative regulation of gene expression, epigenetic SPAC15A10.03c
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality YGL163C
GO:0032200
IEA
PLAZA Integrative Orthologytelomere organization YGL163C
GO:2000113
IEA
PLAZA Integrative Orthologynegative regulation of cellular macromolecule biosynthetic process SPAC15A10.03c
GO:0050790
IEA
PLAZA Integrative Orthologyregulation of catalytic activity YGL163C
GO:0045132
IEA
PLAZA Integrative Orthologymeiotic chromosome segregation YBR073W
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process AT3G24340
GO:0045892
IEA
PLAZA Integrative Orthologynegative regulation of transcription, DNA-templated SPAC15A10.03c
GO:0030702
IEA
PLAZA Integrative Orthologychromatin silencing at centromere SPAC15A10.03c
GO:0060249
IEA
PLAZA Integrative Orthologyanatomical structure homeostasis YGL163C
GO:1902679
IEA
PLAZA Integrative Orthologynegative regulation of RNA biosynthetic process SPAC15A10.03c
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process AT3G24340
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process SPAC15A10.03c
GO:0007135
IEA
PLAZA Integrative Orthologymeiosis II YBR073W
GO:1900370
IEA
PLAZA Integrative Orthologypositive regulation of RNA interference AT3G24340

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016817
IEA
Genome Projecthydrolase activity, acting on acid anhydrides
GO:0005524
IEA
Genome ProjectATP binding
GO:0015616
IEA
PLAZA Integrative OrthologyDNA translocase activity YBR073W
GO:0017111
IEA
PLAZA Integrative Orthologynucleoside-triphosphatase activity SPAC15A10.03c
GO:0016818
IEA
PLAZA Integrative Orthologyhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides SPAC15A10.03c
GO:0008094
IEA
PLAZA Integrative OrthologyDNA-dependent ATPase activity SPAC15A10.03c
GO:0036310
IEA
PLAZA Integrative Orthologyannealing helicase activity ENSG00000085999
GO:0097617
IEA
PLAZA Integrative Orthologyannealing activity ENSG00000085999
GO:0042623
IEA
PLAZA Integrative OrthologyATPase activity, coupled SPAC15A10.03c
GO:0033170
IEA
PLAZA Integrative Orthologyprotein-DNA loading ATPase activity SPAC15A10.03c
GO:0016462
IEA
PLAZA Integrative Orthologypyrophosphatase activity SPAC15A10.03c
GO:0003678
IEA
PLAZA Integrative OrthologyDNA helicase activity ENSG00000197275
GO:0003677
IEA
PLAZA Integrative OrthologyDNA binding SPAC22F3.03c
GO:0003676
IEA
PLAZA Integrative Orthologynucleic acid binding SPAC22F3.03c
GO:0140097
IEA
PLAZA Integrative Orthologycatalytic activity, acting on DNA YBR073W
GO:0140098
IEA
PLAZA Integrative Orthologycatalytic activity, acting on RNA ENSG00000197275
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding AT3G19210
GO:0003724
IEA
PLAZA Integrative OrthologyRNA helicase activity ENSG00000197275
GO:0004386
IEA
PLAZA Integrative Orthologyhelicase activity ENSG00000197275
GO:0003690
IEA
PLAZA Integrative Orthologydouble-stranded DNA binding YBR073W
GO:0016887
IEA
PLAZA Integrative OrthologyATPase activity SPAC15A10.03c

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus11
GO:0005819
IEA
PLAZA Integrative Orthologyspindle SPAC15A10.03c
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000186871
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part SPAC15A10.03c
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000085999
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPAC15A10.03c
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part SPAC15A10.03c
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000085999
GO:0072686
IEA
PLAZA Integrative Orthologymitotic spindle SPAC15A10.03c
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000085999
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPAC15A10.03c
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex ENSG00000085999
GO:0005829
IEA
PLAZA Integrative Orthologycytosol SPAC22F3.03c
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton SPAC15A10.03c
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm SPAC22F3.03c
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton SPAC15A10.03c
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000085999
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPAC15A10.03c
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000085999
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part SPAC15A10.03c
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part SPAC22F3.03c
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPAC15A10.03c
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000085999
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPAC15A10.03c
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPAC15A10.03c

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000330SNF2-related, N-terminal domain
IPR001650Helicase, C-terminal
IPR013967Rad54, N-terminal
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.
KeggID Description
K10875RAD54L, RAD54; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-]
No chloroplast target sequence found.