Gene: ENSG00000274571 (Homo sapiens)

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Gene Identifier
ENSG00000274571
Transcript Identifier
ENST00000610424
Gene Type
Coding gene
Location
CHR_HSCHR19_4_CTG3_1 : 906222-924193 : negative

Family Information

Homologous gene family
HOM02SEM000951
(50 genes in 5 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
NLR family, pyrin domain containing 7

Identifiers

Type Value
pidENSP00000482887
HGNC22947
UniprotQ8WX94
RefSeq_mRNANM_001127255.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1905246
IDA
Gene Ontologynegative regulation of aspartic-type peptidase activity1
GO:1900016
IMP
Gene Ontologynegative regulation of cytokine production involved in inflammatory response1
GO:0071347
IEP
Gene Ontologycellular response to interleukin-11
GO:0071222
IEP
Gene Ontologycellular response to lipopolysaccharide1
GO:0050713
IMP
Gene Ontologynegative regulation of interleukin-1 beta secretion1
GO:0010955
IDA
Gene Ontologynegative regulation of protein processing1
GO:0032610
IEA
PLAZA Integrative Orthologyinterleukin-1 alpha production ENSG00000276780
GO:0032732
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 production ENSG00000278789
GO:0031400
IEA
PLAZA Integrative Orthologynegative regulation of protein modification process ENSG00000142405
GO:0032731
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 beta production ENSG00000278789
GO:0050703
IEA
PLAZA Integrative Orthologyinterleukin-1 alpha secretion ENSG00000276780
GO:0032730
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 alpha production ENSG00000276780
GO:0050705
IEA
PLAZA Integrative Orthologyregulation of interleukin-1 alpha secretion ENSG00000276780
GO:0010604
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule metabolic process ENSG00000278789
GO:0043065
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic process ENSG00000278789
GO:0002674
IEA
PLAZA Integrative Orthologynegative regulation of acute inflammatory response ENSG00000162711
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000278789
GO:0002673
IEA
PLAZA Integrative Orthologyregulation of acute inflammatory response ENSG00000162711
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction ENSG00000158077
GO:0042089
IEA
PLAZA Integrative Orthologycytokine biosynthetic process ENSG00000142405
GO:0002793
IEA
PLAZA Integrative Orthologypositive regulation of peptide secretion ENSG00000278789
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated ENSG00000278789
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated ENSG00000278789
GO:0050829
IEA
PLAZA Integrative Orthologydefense response to Gram-negative bacterium ENSG00000276780
GO:0072604
IEA
PLAZA Integrative Orthologyinterleukin-6 secretion ENSG00000276780
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process ENSG00000158077
GO:0010950
IEA
PLAZA Integrative Orthologypositive regulation of endopeptidase activity ENSG00000278789
GO:0072606
IEA
PLAZA Integrative Orthologyinterleukin-8 secretion ENSG00000276780
GO:0010952
IEA
PLAZA Integrative Orthologypositive regulation of peptidase activity ENSG00000278789
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process ENSG00000276230
GO:0001568
IEA
PLAZA Integrative Orthologyblood vessel development ENSG00000276230
GO:0009968
IEA
PLAZA Integrative Orthologynegative regulation of signal transduction ENSG00000142405
GO:0051222
IEA
PLAZA Integrative Orthologypositive regulation of protein transport ENSG00000278789
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction ENSG00000158077
GO:0051345
IEA
PLAZA Integrative Orthologypositive regulation of hydrolase activity ENSG00000278789
GO:0006468
IEA
PLAZA Integrative Orthologyprotein phosphorylation ENSG00000142405
GO:0045345
IEA
PLAZA Integrative Orthologypositive regulation of MHC class I biosynthetic process ENSG00000142405
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process ENSG00000278789
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process ENSG00000278789
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process ENSG00000142405
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development ENSG00000276230
GO:0070997
IEA
PLAZA Integrative Orthologyneuron death ENSG00000179709
GO:0032635
IEA
PLAZA Integrative Orthologyinterleukin-6 production ENSG00000142405
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000278789
GO:0032755
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-6 production ENSG00000276780
GO:0052548
IEA
PLAZA Integrative Orthologyregulation of endopeptidase activity ENSG00000278789
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis ENSG00000091592
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization ENSG00000091592
GO:0045341
IEA
PLAZA Integrative OrthologyMHC class I biosynthetic process ENSG00000142405
GO:0048731
IEA
PLAZA Integrative Orthologysystem development ENSG00000276230
GO:0045343
IEA
PLAZA Integrative Orthologyregulation of MHC class I biosynthetic process ENSG00000142405
GO:0032637
IEA
PLAZA Integrative Orthologyinterleukin-8 production ENSG00000276780
GO:0032757
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-8 production ENSG00000276780
GO:0043281
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity involved in apoptotic process ENSG00000278789
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism ENSG00000276780
GO:0043280
IEA
PLAZA Integrative Orthologypositive regulation of cysteine-type endopeptidase activity involved in apoptotic process ENSG00000278789
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process ENSG00000278789
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium ENSG00000276780
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process ENSG00000278789
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process ENSG00000278789
GO:0038061
IEA
PLAZA Integrative OrthologyNIK/NF-kappaB signaling ENSG00000142405
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process ENSG00000278789
GO:1904784
IEA
PLAZA Integrative OrthologyNLRP1 inflammasome complex assembly ENSG00000091592
GO:0032088
IEA
PLAZA Integrative Orthologynegative regulation of NF-kappaB transcription factor activity ENSG00000278789
GO:0070646
IEA
PLAZA Integrative Orthologyprotein modification by small protein removal ENSG00000162711
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process ENSG00000158077
GO:0070647
IEA
PLAZA Integrative Orthologyprotein modification by small protein conjugation or removal ENSG00000162711
GO:0006919
IEA
PLAZA Integrative Orthologyactivation of cysteine-type endopeptidase activity involved in apoptotic process ENSG00000091592
GO:0035239
IEA
PLAZA Integrative Orthologytube morphogenesis ENSG00000276230
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process ENSG00000278789
GO:0022603
IEA
PLAZA Integrative Orthologyregulation of anatomical structure morphogenesis ENSG00000276230
GO:0046777
IEA
PLAZA Integrative Orthologyprotein autophosphorylation ENSG00000142405
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly ENSG00000091592
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process ENSG00000142405
GO:0042326
IEA
PLAZA Integrative Orthologynegative regulation of phosphorylation ENSG00000142405
GO:0042325
IEA
PLAZA Integrative Orthologyregulation of phosphorylation ENSG00000142405
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process ENSG00000142405
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification ENSG00000142405
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process ENSG00000142405
GO:0016579
IEA
PLAZA Integrative Orthologyprotein deubiquitination ENSG00000162711
GO:0001525
IEA
PLAZA Integrative Orthologyangiogenesis ENSG00000276230
GO:2000778
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-6 secretion ENSG00000276780
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process ENSG00000278789
GO:0032270
IEA
PLAZA Integrative Orthologypositive regulation of cellular protein metabolic process ENSG00000278789
GO:0051259
IEA
PLAZA Integrative Orthologyprotein complex oligomerization ENSG00000162711
GO:2001056
IEA
PLAZA Integrative Orthologypositive regulation of cysteine-type endopeptidase activity ENSG00000278789
GO:0010942
IEA
PLAZA Integrative Orthologypositive regulation of cell death ENSG00000278789
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death ENSG00000278789
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process ENSG00000278789
GO:0002526
IEA
PLAZA Integrative Orthologyacute inflammatory response ENSG00000162711
GO:0043085
IEA
PLAZA Integrative Orthologypositive regulation of catalytic activity ENSG00000278789
GO:0032715
IEA
PLAZA Integrative Orthologynegative regulation of interleukin-6 production ENSG00000142405
GO:1900426
IEA
PLAZA Integrative Orthologypositive regulation of defense response to bacterium ENSG00000276780
GO:1900424
IEA
PLAZA Integrative Orthologyregulation of defense response to bacterium ENSG00000276780
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction ENSG00000142405
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction ENSG00000142405
GO:0048646
IEA
PLAZA Integrative Orthologyanatomical structure formation involved in morphogenesis ENSG00000276230
GO:0045936
IEA
PLAZA Integrative Orthologynegative regulation of phosphate metabolic process ENSG00000142405
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction ENSG00000142405
GO:0050714
IEA
PLAZA Integrative Orthologypositive regulation of protein secretion ENSG00000278789
GO:0050716
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 secretion ENSG00000278789
GO:0050715
IEA
PLAZA Integrative Orthologypositive regulation of cytokine secretion ENSG00000278789
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process ENSG00000278789
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process ENSG00000278789
GO:0032606
IEA
PLAZA Integrative Orthologytype I interferon production ENSG00000160505
GO:0051247
IEA
PLAZA Integrative Orthologypositive regulation of protein metabolic process ENSG00000278789
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process ENSG00000278789
GO:0048514
IEA
PLAZA Integrative Orthologyblood vessel morphogenesis ENSG00000276230
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death ENSG00000278789
GO:0043068
IEA
PLAZA Integrative Orthologypositive regulation of programmed cell death ENSG00000278789
GO:0050717
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 alpha secretion ENSG00000276780
GO:0050718
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-1 beta secretion ENSG00000278789
GO:0008063
IEA
PLAZA Integrative OrthologyToll signaling pathway ENSG00000142405
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death ENSG00000278789
GO:0010563
IEA
PLAZA Integrative Orthologynegative regulation of phosphorus metabolic process ENSG00000142405
GO:0048232
IEA
PLAZA Integrative Orthologymale gamete generation ENSG00000158077
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway ENSG00000142405
GO:0045751
IEA
PLAZA Integrative Orthologynegative regulation of Toll signaling pathway ENSG00000142405
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process ENSG00000158077
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process ENSG00000278789
GO:0007283
IEA
PLAZA Integrative Orthologyspermatogenesis ENSG00000158077
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction ENSG00000142405
GO:0035295
IEA
PLAZA Integrative Orthologytube development ENSG00000276230
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation ENSG00000142405
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process ENSG00000278789
GO:0010557
IEA
PLAZA Integrative Orthologypositive regulation of macromolecule biosynthetic process ENSG00000142405
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process ENSG00000278789
GO:0032103
IEA
PLAZA Integrative Orthologypositive regulation of response to external stimulus ENSG00000276780
GO:0010558
IEA
PLAZA Integrative Orthologynegative regulation of macromolecule biosynthetic process ENSG00000142405
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process ENSG00000278789
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus ENSG00000142405
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription ENSG00000278789
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction ENSG00000142405
GO:0045862
IEA
PLAZA Integrative Orthologypositive regulation of proteolysis ENSG00000278789
GO:1901566
IEA
PLAZA Integrative Orthologyorganonitrogen compound biosynthetic process ENSG00000142405
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation ENSG00000158077
GO:1902532
IEA
PLAZA Integrative Orthologynegative regulation of intracellular signal transduction ENSG00000142405
GO:0007154
IEA
PLAZA Integrative Orthologycell communication ENSG00000142405
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction ENSG00000142405
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development ENSG00000276230
GO:1904951
IEA
PLAZA Integrative Orthologypositive regulation of establishment of protein localization ENSG00000278789
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction ENSG00000158077
GO:0032479
IEA
PLAZA Integrative Orthologyregulation of type I interferon production ENSG00000160505
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000278789
GO:0051174
IEA
PLAZA Integrative Orthologyregulation of phosphorus metabolic process ENSG00000142405
GO:0042226
IEA
PLAZA Integrative Orthologyinterleukin-6 biosynthetic process ENSG00000142405
GO:0044093
IEA
PLAZA Integrative Orthologypositive regulation of molecular function ENSG00000278789
GO:0043433
IEA
PLAZA Integrative Orthologynegative regulation of DNA-binding transcription factor activity ENSG00000278789
GO:0042107
IEA
PLAZA Integrative Orthologycytokine metabolic process ENSG00000142405
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process ENSG00000278789
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process ENSG00000278789
GO:0031953
IEA
PLAZA Integrative Orthologynegative regulation of protein autophosphorylation ENSG00000142405
GO:0031399
IEA
PLAZA Integrative Orthologyregulation of protein modification process ENSG00000142405
GO:0031952
IEA
PLAZA Integrative Orthologyregulation of protein autophosphorylation ENSG00000142405
GO:0051606
IEA
PLAZA Integrative Orthologydetection of stimulus ENSG00000162711
GO:0002833
IEA
PLAZA Integrative Orthologypositive regulation of response to biotic stimulus ENSG00000276780
GO:0051047
IEA
PLAZA Integrative Orthologypositive regulation of secretion ENSG00000278789
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis ENSG00000091592
GO:0002831
IEA
PLAZA Integrative Orthologyregulation of response to biotic stimulus ENSG00000276780
GO:0051050
IEA
PLAZA Integrative Orthologypositive regulation of transport ENSG00000278789
GO:0009595
IEA
PLAZA Integrative Orthologydetection of biotic stimulus ENSG00000162711
GO:0051173
IEA
PLAZA Integrative Orthologypositive regulation of nitrogen compound metabolic process ENSG00000278789
GO:0001819
IEA
PLAZA Integrative Orthologypositive regulation of cytokine production ENSG00000278789
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development ENSG00000276230
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process ENSG00000278789
GO:0031325
IEA
PLAZA Integrative Orthologypositive regulation of cellular metabolic process ENSG00000278789
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication ENSG00000142405
GO:0032650
IEA
PLAZA Integrative Orthologyregulation of interleukin-1 alpha production ENSG00000276780
GO:0072358
IEA
PLAZA Integrative Orthologycardiovascular system development ENSG00000276230
GO:0072359
IEA
PLAZA Integrative Orthologycirculatory system development ENSG00000276230
GO:0001933
IEA
PLAZA Integrative Orthologynegative regulation of protein phosphorylation ENSG00000142405
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process ENSG00000278789
GO:0001932
IEA
PLAZA Integrative Orthologyregulation of protein phosphorylation ENSG00000142405
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication ENSG00000142405
GO:0010648
IEA
PLAZA Integrative Orthologynegative regulation of cell communication ENSG00000142405
GO:0031327
IEA
PLAZA Integrative Orthologynegative regulation of cellular biosynthetic process ENSG00000142405
GO:0007249
IEA
PLAZA Integrative OrthologyI-kappaB kinase/NF-kappaB signaling ENSG00000142405
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization ENSG00000091592
GO:0019220
IEA
PLAZA Integrative Orthologyregulation of phosphate metabolic process ENSG00000142405
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000278789
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process ENSG00000278789
GO:0043124
IEA
PLAZA Integrative Orthologynegative regulation of I-kappaB kinase/NF-kappaB signaling ENSG00000142405
GO:0042036
IEA
PLAZA Integrative Orthologynegative regulation of cytokine biosynthetic process ENSG00000142405
GO:0042035
IEA
PLAZA Integrative Orthologyregulation of cytokine biosynthetic process ENSG00000142405
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis ENSG00000276230
GO:0043122
IEA
PLAZA Integrative Orthologyregulation of I-kappaB kinase/NF-kappaB signaling ENSG00000142405
GO:0009890
IEA
PLAZA Integrative Orthologynegative regulation of biosynthetic process ENSG00000142405
GO:0009891
IEA
PLAZA Integrative Orthologypositive regulation of biosynthetic process ENSG00000142405
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000278789
GO:0009893
IEA
PLAZA Integrative Orthologypositive regulation of metabolic process ENSG00000278789
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process ENSG00000278789
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process ENSG00000278789
GO:0032677
IEA
PLAZA Integrative Orthologyregulation of interleukin-8 production ENSG00000276780
GO:2000484
IEA
PLAZA Integrative Orthologypositive regulation of interleukin-8 secretion ENSG00000276780
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription ENSG00000278789
GO:0032675
IEA
PLAZA Integrative Orthologyregulation of interleukin-6 production ENSG00000142405
GO:0023052
IEA
PLAZA Integrative Orthologysignaling ENSG00000142405
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling ENSG00000142405
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling ENSG00000142405
GO:0031349
IEA
PLAZA Integrative Orthologypositive regulation of defense response ENSG00000276780
GO:0023057
IEA
PLAZA Integrative Orthologynegative regulation of signaling ENSG00000142405
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process ENSG00000278789
GO:0008592
IEA
PLAZA Integrative Orthologyregulation of Toll signaling pathway ENSG00000142405
GO:1903532
IEA
PLAZA Integrative Orthologypositive regulation of secretion by cell ENSG00000278789
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly ENSG00000091592
GO:0051402
IEA
PLAZA Integrative Orthologyneuron apoptotic process ENSG00000091592
GO:2000116
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity ENSG00000278789
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process ENSG00000278789
GO:0001944
IEA
PLAZA Integrative Orthologyvasculature development ENSG00000276230
GO:0008219
IEA
PLAZA Integrative Orthologycell death ENSG00000278789
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process ENSG00000276230
GO:0051090
IEA
PLAZA Integrative Orthologyregulation of DNA-binding transcription factor activity ENSG00000278789
GO:0051092
IEA
PLAZA Integrative Orthologypositive regulation of NF-kappaB transcription factor activity ENSG00000162711
GO:0051091
IEA
PLAZA Integrative Orthologypositive regulation of DNA-binding transcription factor activity ENSG00000162711
GO:1901223
IEA
PLAZA Integrative Orthologynegative regulation of NIK/NF-kappaB signaling ENSG00000162711
GO:0045765
IEA
PLAZA Integrative Orthologyregulation of angiogenesis ENSG00000276230
GO:1901224
IEA
PLAZA Integrative Orthologypositive regulation of NIK/NF-kappaB signaling ENSG00000142405
GO:1901342
IEA
PLAZA Integrative Orthologyregulation of vasculature development ENSG00000276230
GO:1901222
IEA
PLAZA Integrative Orthologyregulation of NIK/NF-kappaB signaling ENSG00000142405
GO:0043902
IEA
PLAZA Integrative Orthologypositive regulation of multi-organism process ENSG00000276780
GO:0045408
IEA
PLAZA Integrative Orthologyregulation of interleukin-6 biosynthetic process ENSG00000142405
GO:2000482
IEA
PLAZA Integrative Orthologyregulation of interleukin-8 secretion ENSG00000276780
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process ENSG00000276780
GO:0045409
IEA
PLAZA Integrative Orthologynegative regulation of interleukin-6 biosynthetic process ENSG00000142405

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0089720
IPI
Gene Ontologycaspase binding1
GO:0019966
IPI
Gene Ontologyinterleukin-1 binding1
GO:0019828
IDA
Gene Ontologyaspartic-type endopeptidase inhibitor activity1
GO:0030554
IEA
PLAZA Integrative Orthologyadenyl nucleotide binding ENSG00000091592
GO:0017111
IEA
PLAZA Integrative Orthologynucleoside-triphosphatase activity ENSG00000276780
GO:0016817
IEA
PLAZA Integrative Orthologyhydrolase activity, acting on acid anhydrides ENSG00000276780
GO:0016818
IEA
PLAZA Integrative Orthologyhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ENSG00000276780
GO:0043168
IEA
PLAZA Integrative Orthologyanion binding ENSG00000091592
GO:0043167
IEA
PLAZA Integrative Orthologyion binding ENSG00000091592
GO:0008428
IEA
PLAZA Integrative Orthologyribonuclease inhibitor activity ENSG00000276230
GO:0032090
IEA
PLAZA Integrative OrthologyPyrin domain binding ENSG00000278789
GO:1901265
IEA
PLAZA Integrative Orthologynucleoside phosphate binding ENSG00000091592
GO:0016462
IEA
PLAZA Integrative Orthologypyrophosphatase activity ENSG00000276780
GO:0003824
IEA
PLAZA Integrative Orthologycatalytic activity ENSG00000276780
GO:0097367
IEA
PLAZA Integrative Orthologycarbohydrate derivative binding ENSG00000091592
GO:0003723
IEA
PLAZA Integrative OrthologyRNA binding ENSG00000179873
GO:0036094
IEA
PLAZA Integrative Orthologysmall molecule binding ENSG00000091592
GO:0016787
IEA
PLAZA Integrative Orthologyhydrolase activity ENSG00000276780
GO:0017076
IEA
PLAZA Integrative Orthologypurine nucleotide binding ENSG00000091592
GO:0005539
IEA
PLAZA Integrative Orthologyglycosaminoglycan binding ENSG00000162711
GO:0097159
IEA
PLAZA Integrative Orthologyorganic cyclic compound binding ENSG00000179873
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding ENSG00000162711
GO:0005524
IEA
PLAZA Integrative OrthologyATP binding ENSG00000091592
GO:0003924
IEA
PLAZA Integrative OrthologyGTPase activity ENSG00000276780
GO:0035639
IEA
PLAZA Integrative Orthologypurine ribonucleoside triphosphate binding ENSG00000091592
GO:0008144
IEA
PLAZA Integrative Orthologydrug binding ENSG00000091592
GO:0003676
IEA
PLAZA Integrative Orthologynucleic acid binding ENSG00000179873
GO:0000166
IEA
PLAZA Integrative Orthologynucleotide binding ENSG00000091592
GO:1901363
IEA
PLAZA Integrative Orthologyheterocyclic compound binding ENSG00000179873
GO:0042834
IEA
PLAZA Integrative Orthologypeptidoglycan binding ENSG00000162711
GO:0032555
IEA
PLAZA Integrative Orthologypurine ribonucleotide binding ENSG00000091592
GO:0032553
IEA
PLAZA Integrative Orthologyribonucleotide binding ENSG00000091592
GO:0032559
IEA
PLAZA Integrative Orthologyadenyl ribonucleotide binding ENSG00000091592
GO:0019904
IEA
PLAZA Integrative Orthologyprotein domain specific binding ENSG00000278789
GO:0016887
IEA
PLAZA Integrative OrthologyATPase activity ENSG00000276780

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005575
ND
Gene Ontologycellular_component
GO:0019897
IEA
PLAZA Integrative Orthologyextrinsic component of plasma membrane ENSG00000276780
GO:0019898
IEA
PLAZA Integrative Orthologyextrinsic component of membrane ENSG00000276780
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000276780
GO:0061702
IEA
PLAZA Integrative Orthologyinflammasome complex ENSG00000091592
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex ENSG00000276230
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000278789
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000276230
GO:0098687
IEA
PLAZA Integrative Orthologychromosomal region ENSG00000278789
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen ENSG00000278789
GO:0005576
IEA
PLAZA Integrative Orthologyextracellular region ENSG00000276230
GO:0005694
IEA
PLAZA Integrative Orthologychromosome ENSG00000278789
GO:0031982
IEA
PLAZA Integrative Orthologyvesicle ENSG00000276230
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen ENSG00000278789
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome ENSG00000278789
GO:0072559
IEA
PLAZA Integrative OrthologyNLRP3 inflammasome complex ENSG00000162711
GO:0012505
IEA
PLAZA Integrative Orthologyendomembrane system ENSG00000278789
GO:0072558
IEA
PLAZA Integrative OrthologyNLRP1 inflammasome complex ENSG00000091592
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen ENSG00000278789
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part ENSG00000278789
GO:0044424
IEA
PLAZA Integrative Orthologyintracellular part ENSG00000278789
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part ENSG00000278789
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part ENSG00000276780
GO:0044421
IEA
PLAZA Integrative Orthologyextracellular region part ENSG00000276230
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part ENSG00000278789
GO:0005654
IEA
PLAZA Integrative Orthologynucleoplasm ENSG00000276230
GO:0000784
IEA
PLAZA Integrative Orthologynuclear chromosome, telomeric region ENSG00000278789
GO:0000781
IEA
PLAZA Integrative Orthologychromosome, telomeric region ENSG00000278789
GO:0005794
IEA
PLAZA Integrative OrthologyGolgi apparatus ENSG00000278789
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery ENSG00000276780
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm ENSG00000278789
GO:0005615
IEA
PLAZA Integrative Orthologyextracellular space ENSG00000276230
GO:0005622
IEA
PLAZA Integrative Orthologyintracellular ENSG00000278789
GO:0044464
IEA
PLAZA Integrative Orthologycell part ENSG00000278789
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000276230
GO:0044459
IEA
PLAZA Integrative Orthologyplasma membrane part ENSG00000276780
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part ENSG00000278789
GO:0032311
IEA
PLAZA Integrative Orthologyangiogenin-PRI complex ENSG00000276230
GO:0005634
IEA
PLAZA Integrative Orthologynucleus ENSG00000278789
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane ENSG00000276780
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part ENSG00000278789
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part ENSG00000278789
GO:0044445
IEA
PLAZA Integrative Orthologycytosolic part ENSG00000091592
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle ENSG00000278789
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen ENSG00000278789
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000276230
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle ENSG00000278789
GO:0005623
IEA
PLAZA Integrative Orthologycell ENSG00000278789
GO:0043227
IEA
PLAZA Integrative Orthologymembrane-bounded organelle ENSG00000278789
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle ENSG00000278789
GO:0043226
IEA
PLAZA Integrative Orthologyorganelle ENSG00000278789
GO:0043229
IEA
PLAZA Integrative Orthologyintracellular organelle ENSG00000278789

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
No InterPro domains detected for this gene.
No MapMan annotations defined for this gene.
KeggID Description
K19409NLRP2; NACHT, LRR and PYD domains-containing protein 2
No chloroplast target sequence found.