Gene: ENSG00000249915 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000249915
Transcript Identifier
ENST00000264933
Gene Type
Coding gene
Location
5 : 271721-314515 : positive

Family Information

Homologous gene family
HOM02SEM004863
(17 genes in 7 species)
specific family

Descriptions

gene_descr
programmed cell death 6

Identifiers

Type Value
pidENSP00000264933
HGNC8765
UniprotO75340
RefSeq_mRNANM_013232.3
EMBLAC010442
EMBLAC021087
EMBLAC118458
EMBLAF035606
EMBLAK315370
EMBLBC012384
EMBLBC106706
EMBLBC110291
EMBLBT020072
EMBLCB991882
EMBLCH471235
EMBLU58773

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1902527
IMP
Genome Projectpositive regulation of protein monoubiquitination
GO:1902527
IMP
Gene Ontologypositive regulation of protein monoubiquitination1
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:0097190
TAS
Gene Ontologyapoptotic signaling pathway2
GO:0051898
IDA
Genome Projectnegative regulation of protein kinase B signaling
GO:0051898
IDA
Gene Ontologynegative regulation of protein kinase B signaling3
GO:0051592
ISS
Genome Projectresponse to calcium ion
GO:0051592
ISS
Gene Ontologyresponse to calcium ion
GO:0048208
IMP
Genome ProjectCOPII vesicle coating
GO:0048208
IMP
Gene OntologyCOPII vesicle coating1
GO:0045766
IDA
Genome Projectpositive regulation of angiogenesis
GO:0045766
IDA
Gene Ontologypositive regulation of angiogenesis3
GO:0043280
IDA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043280
IDA
Gene Ontologypositive regulation of cysteine-type endopeptidase activity involved in apoptotic process4
GO:0036324
IDA
Genome Projectvascular endothelial growth factor receptor-2 signaling pathway
GO:0036324
IDA
Gene Ontologyvascular endothelial growth factor receptor-2 signaling pathway3
GO:0034605
IDA
Genome Projectcellular response to heat
GO:0034605
IDA
Gene Ontologycellular response to heat5
GO:0032007
IDA
Genome Projectnegative regulation of TOR signaling
GO:0032007
IDA
Gene Ontologynegative regulation of TOR signaling3
GO:0030948
IDA
Genome Projectnegative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0030948
IDA
Gene Ontologynegative regulation of vascular endothelial growth factor receptor signaling pathway3
GO:0014032
IMP
Genome Projectneural crest cell development
GO:0014032
IMP
Gene Ontologyneural crest cell development1
GO:0014029
IMP
Genome Projectneural crest formation
GO:0014029
IMP
Gene Ontologyneural crest formation1
GO:0010595
IDA
Genome Projectpositive regulation of endothelial cell migration
GO:0010595
IDA
Gene Ontologypositive regulation of endothelial cell migration3
GO:0006919
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006888
IMP
Genome ProjectER to Golgi vesicle-mediated transport
GO:0006888
IMP
Gene OntologyER to Golgi vesicle-mediated transport1 6
GO:0006886
IDA
Genome Projectintracellular protein transport
GO:0006886
IDA
Gene Ontologyintracellular protein transport5
GO:0006508
IEA
Genome Projectproteolysis
GO:0001938
IDA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0001938
IDA
Gene Ontologypositive regulation of endothelial cell proliferation3
GO:0001525
IEA
Genome Projectangiogenesis
GO:0010562
IEA
PLAZA Integrative Orthologypositive regulation of phosphorus metabolic process FBgn0086378
GO:0001934
IEA
PLAZA Integrative Orthologypositive regulation of protein phosphorylation FBgn0086378
GO:0046330
IEA
PLAZA Integrative Orthologypositive regulation of JNK cascade FBgn0086378
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0086378
GO:0001932
IEA
PLAZA Integrative Orthologyregulation of protein phosphorylation FBgn0086378
GO:0003400
IEA
PLAZA Integrative Orthologyregulation of COPII vesicle coating YGR058W
GO:0046328
IEA
PLAZA Integrative Orthologyregulation of JNK cascade FBgn0086378
GO:0042325
IEA
PLAZA Integrative Orthologyregulation of phosphorylation FBgn0086378
GO:0006796
IEA
PLAZA Integrative Orthologyphosphate-containing compound metabolic process FBgn0086378
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle YGR058W
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction YGR058W
GO:0043410
IEA
PLAZA Integrative Orthologypositive regulation of MAPK cascade FBgn0086378
GO:0006793
IEA
PLAZA Integrative Orthologyphosphorus metabolic process FBgn0086378
GO:0043254
IEA
PLAZA Integrative Orthologyregulation of protein complex assembly YGR058W
GO:0007163
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cell polarity YGR058W
GO:0031098
IEA
PLAZA Integrative Orthologystress-activated protein kinase signaling cascade FBgn0086378
GO:0007121
IEA
PLAZA Integrative Orthologybipolar cellular bud site selection YGR058W
GO:0007120
IEA
PLAZA Integrative Orthologyaxial cellular bud site selection YGR058W
GO:0042327
IEA
PLAZA Integrative Orthologypositive regulation of phosphorylation FBgn0086378
GO:0070304
IEA
PLAZA Integrative Orthologypositive regulation of stress-activated protein kinase signaling cascade FBgn0086378
GO:0016310
IEA
PLAZA Integrative Orthologyphosphorylation FBgn0086378
GO:0032386
IEA
PLAZA Integrative Orthologyregulation of intracellular transport YGR058W
GO:0070302
IEA
PLAZA Integrative Orthologyregulation of stress-activated protein kinase signaling cascade FBgn0086378
GO:0019220
IEA
PLAZA Integrative Orthologyregulation of phosphate metabolic process FBgn0086378
GO:0000281
IEA
PLAZA Integrative Orthologymitotic cytokinesis YGR058W
GO:0000282
IEA
PLAZA Integrative Orthologycellular bud site selection YGR058W
GO:0060628
IEA
PLAZA Integrative Orthologyregulation of ER to Golgi vesicle-mediated transport YGR058W
GO:0032505
IEA
PLAZA Integrative Orthologyreproduction of a single-celled organism YGR058W
GO:0000165
IEA
PLAZA Integrative OrthologyMAPK cascade FBgn0086378
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0086378
GO:0051301
IEA
PLAZA Integrative Orthologycell division YGR058W
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle YGR058W
GO:0006468
IEA
PLAZA Integrative Orthologyprotein phosphorylation FBgn0086378
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction FBgn0086378
GO:0060627
IEA
PLAZA Integrative Orthologyregulation of vesicle-mediated transport YGR058W
GO:0007114
IEA
PLAZA Integrative Orthologycell budding YGR058W
GO:0000910
IEA
PLAZA Integrative Orthologycytokinesis YGR058W
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization YGR058W
GO:0090113
IEA
PLAZA Integrative Orthologyregulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis YGR058W
GO:0043408
IEA
PLAZA Integrative Orthologyregulation of MAPK cascade FBgn0086378
GO:0060341
IEA
PLAZA Integrative Orthologyregulation of cellular localization YGR058W
GO:0019954
IEA
PLAZA Integrative Orthologyasexual reproduction YGR058W
GO:0032874
IEA
PLAZA Integrative Orthologypositive regulation of stress-activated MAPK cascade FBgn0086378
GO:0030010
IEA
PLAZA Integrative Orthologyestablishment of cell polarity YGR058W
GO:0032872
IEA
PLAZA Integrative Orthologyregulation of stress-activated MAPK cascade FBgn0086378
GO:0051174
IEA
PLAZA Integrative Orthologyregulation of phosphorus metabolic process FBgn0086378
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0086378
GO:0048209
IEA
PLAZA Integrative Orthologyregulation of vesicle targeting, to, from or within Golgi YGR058W
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0086378
GO:0061640
IEA
PLAZA Integrative Orthologycytoskeleton-dependent cytokinesis YGR058W
GO:0045937
IEA
PLAZA Integrative Orthologypositive regulation of phosphate metabolic process FBgn0086378
GO:0051403
IEA
PLAZA Integrative Orthologystress-activated MAPK cascade FBgn0086378
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization YGR058W
GO:0044087
IEA
PLAZA Integrative Orthologyregulation of cellular component biogenesis YGR058W
GO:0051049
IEA
PLAZA Integrative Orthologyregulation of transport YGR058W
GO:0023014
IEA
PLAZA Integrative Orthologysignal transduction by protein phosphorylation FBgn0086378
GO:0007254
IEA
PLAZA Integrative OrthologyJNK cascade FBgn0086378
GO:0080135
IEA
PLAZA Integrative Orthologyregulation of cellular response to stress FBgn0086378
GO:0080134
IEA
PLAZA Integrative Orthologyregulation of response to stress FBgn0086378
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process YGR058W
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process YGR058W

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0060090
IMP
Genome Projectmolecular adaptor activity
GO:0060090
IMP
Gene Ontologymolecular adaptor activity1 7
GO:0048306
IPI
Genome Projectcalcium-dependent protein binding
GO:0048306
IPI
Gene Ontologycalcium-dependent protein binding1 8 9 10 11 12
GO:0046983
IPI
Genome Projectprotein dimerization activity
GO:0046983
IPI
Gene Ontologyprotein dimerization activity13
GO:0043495
IMP
Genome Projectprotein membrane anchor
GO:0043495
IMP
Gene Ontologyprotein membrane anchor8
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0042803
IDA
Gene Ontologyprotein homodimerization activity14
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding15 16 17 18
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 4 6 9 11 12 14 15 16 17 18 19 20 21 22 23
GO:0005509
IDA
ISS
Genome Projectcalcium ion binding
GO:0005509
IDA
ISS
Gene Ontologycalcium ion binding14
GO:0004198
IBA
Genome Projectcalcium-dependent cysteine-type endopeptidase activity
GO:0000287
ISS
Genome Projectmagnesium ion binding
GO:0000287
ISS
Gene Ontologymagnesium ion binding
GO:0046914
IEA
PLAZA Integrative Orthologytransition metal ion binding YGR058W
GO:0008270
IEA
PLAZA Integrative Orthologyzinc ion binding YGR058W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031463
IDA
Genome ProjectCul3-RING ubiquitin ligase complex
GO:0031463
IDA
Gene OntologyCul3-RING ubiquitin ligase complex1
GO:0070971
IDA, IMP
Genome Projectendoplasmic reticulum exit site
GO:0070971
IDA, IMP
Gene Ontologyendoplasmic reticulum exit site6 8
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome24 25 26
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0031410
IDA
Gene Ontologycytoplasmic vesicle5
GO:0030127
IDA
Genome ProjectCOPII vesicle coat
GO:0030127
IDA
Gene OntologyCOPII vesicle coat1
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005783
IDA
Genome Projectendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum9
GO:0005768
IEA
Genome Projectendosome
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm5 23
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus5 8 9 23
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0005933
IEA
PLAZA Integrative Orthologycellular bud YGR058W
GO:0005935
IEA
PLAZA Integrative Orthologycellular bud neck YGR058W
GO:0005829
IEA
PLAZA Integrative Orthologycytosol YGR058W
GO:0030427
IEA
PLAZA Integrative Orthologysite of polarized growth YGR058W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR018247EF-Hand 1, calcium-binding site

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.