Gene: ENSG00000244687 (Homo sapiens)

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Gene Identifier
ENSG00000244687
Transcript Identifier
ENST00000371677
Gene Type
Coding gene
Location
20 : 50082768-50115575 : negative

Family Information

Homologous gene family
HOM02SEM001158
(45 genes in 25 species)
specific family
Orthologous gene family
ORTHO02SEM001748
(35 genes in 25 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
ubiquitin-conjugating enzyme E2 variant 1

Identifiers

Type Value
pidENSP00000360742
HGNC12494
UniprotQ13404
RefSeq_mRNANM_199144.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070534
IDA
Genome Projectprotein K63-linked ubiquitination
GO:0070534
IDA
Gene Ontologyprotein K63-linked ubiquitination1 2
GO:0070423
TAS
Genome Projectnucleotide-binding oligomerization domain containing signaling pathway
GO:0070423
TAS
Gene Ontologynucleotide-binding oligomerization domain containing signaling pathway
GO:0051092
IMP
TAS
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051092
IMP
TAS
Gene Ontologypositive regulation of NF-kappaB transcription factor activity3
GO:0050852
TAS
Genome ProjectT cell receptor signaling pathway
GO:0045893
TAS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045893
TAS
Gene Ontologypositive regulation of transcription, DNA-templated4
GO:0043123
IMP
TAS
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123
IMP
Gene Ontologypositive regulation of I-kappaB kinase/NF-kappaB signaling3
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0030154
NAS
Genome Projectcell differentiation
GO:0030154
NAS
Gene Ontologycell differentiation5
GO:0007254
TAS
Genome ProjectJNK cascade
GO:0007254
TAS
Gene OntologyJNK cascade
GO:0006355
TAS
Genome Projectregulation of transcription, DNA-templated
GO:0006355
TAS
Gene Ontologyregulation of transcription, DNA-templated4
GO:0006301
IBA
Genome Projectpostreplication repair
GO:0006282
TAS
Genome Projectregulation of DNA repair
GO:0006282
TAS
Gene Ontologyregulation of DNA repair6
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000209
TAS
Gene Ontologyprotein polyubiquitination6
GO:0000187
TAS
Genome Projectactivation of MAPK activity
GO:0000187
TAS
Gene Ontologyactivation of MAPK activity
GO:0070498
TAS
Gene Ontologyinterleukin-1-mediated signaling pathway
GO:0009617
IEA
PLAZA Integrative Orthologyresponse to bacterium FBgn0035601
GO:1903827
IEA
PLAZA Integrative Orthologyregulation of cellular protein localization WBGene00006730
GO:0090325
IEA
PLAZA Integrative Orthologyregulation of locomotion involved in locomotory behavior WBGene00006730
GO:0043933
IEA
PLAZA Integrative Orthologyprotein-containing complex subunit organization YGL087C
GO:0019725
IEA
PLAZA Integrative Orthologycellular homeostasis YGL087C
GO:0010994
IEA
PLAZA Integrative Orthologyfree ubiquitin chain polymerization YGL087C
GO:0010992
IEA
PLAZA Integrative Orthologyubiquitin recycling YGL087C
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0035601
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization WBGene00006730
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0035601
GO:0007626
IEA
PLAZA Integrative Orthologylocomotory behavior WBGene00006730
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0035601
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0035601
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion WBGene00006730
GO:0040012
IEA
PLAZA Integrative Orthologyregulation of locomotion WBGene00006730
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0035601
GO:0060341
IEA
PLAZA Integrative Orthologyregulation of cellular localization WBGene00006730
GO:0034613
IEA
PLAZA Integrative Orthologycellular protein localization WBGene00006730
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YGL087C
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YGL087C
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process YGL087C
GO:0051179
IEA
PLAZA Integrative Orthologylocalization WBGene00006730
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization WBGene00006730
GO:2000008
IEA
PLAZA Integrative Orthologyregulation of protein localization to cell surface WBGene00006730
GO:0031987
IEA
PLAZA Integrative Orthologylocomotion involved in locomotory behavior WBGene00006730
GO:0051258
IEA
PLAZA Integrative Orthologyprotein polymerization YGL087C
GO:0098542
IEA
PLAZA Integrative Orthologydefense response to other organism FBgn0035601
GO:0042742
IEA
PLAZA Integrative Orthologydefense response to bacterium FBgn0035601
GO:0032880
IEA
PLAZA Integrative Orthologyregulation of protein localization WBGene00006730
GO:0065003
IEA
PLAZA Integrative Orthologyprotein-containing complex assembly YGL087C
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality YGL087C
GO:0034622
IEA
PLAZA Integrative Orthologycellular protein-containing complex assembly YGL087C
GO:0051641
IEA
PLAZA Integrative Orthologycellular localization WBGene00006730
GO:0044085
IEA
PLAZA Integrative Orthologycellular component biogenesis YGL087C
GO:0050795
IEA
PLAZA Integrative Orthologyregulation of behavior WBGene00006730
GO:0007610
IEA
PLAZA Integrative Orthologybehavior WBGene00006730
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization WBGene00006730
GO:0022607
IEA
PLAZA Integrative Orthologycellular component assembly YGL087C
GO:0070727
IEA
PLAZA Integrative Orthologycellular macromolecule localization WBGene00006730
GO:0061057
IEA
PLAZA Integrative Orthologypeptidoglycan recognition protein signaling pathway FBgn0035601
GO:0034394
IEA
PLAZA Integrative Orthologyprotein localization to cell surface WBGene00006730

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061630
IBA
Genome Projectubiquitin protein ligase activity
GO:0031625
IBA
Genome Projectubiquitin protein ligase binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 7 8 9
GO:0044390
IEA
PLAZA Integrative Orthologyubiquitin-like protein conjugating enzyme binding WBGene00006730
GO:0061631
IEA
PLAZA Integrative Orthologyubiquitin conjugating enzyme activity SPCC338.05c
GO:0031624
IEA
PLAZA Integrative Orthologyubiquitin conjugating enzyme binding WBGene00006730
GO:0061650
IEA
PLAZA Integrative Orthologyubiquitin-like protein conjugating enzyme activity SPCC338.05c

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome10 11
GO:0035370
IDA
Genome ProjectUBC13-UEV1A complex
GO:0035370
IDA
Gene OntologyUBC13-UEV1A complex1
GO:0031371
IDA
Genome Projectubiquitin conjugating enzyme complex
GO:0031371
IDA
Gene Ontologyubiquitin conjugating enzyme complex3
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm3
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
TAS
Genome Projectnucleus
GO:0005634
TAS
Gene Ontologynucleus4
GO:0000151
IDA
Genome Projectubiquitin ligase complex
GO:0000151
IDA
Gene Ontologyubiquitin ligase complex1
GO:0032991
IDA
Gene Ontologyprotein-containing complex12
GO:0031372
IEA
PLAZA Integrative OrthologyUBC13-MMS2 complex AT2G36060
GO:0043005
IEA
PLAZA Integrative Orthologyneuron projection WBGene00006730
GO:0097458
IEA
PLAZA Integrative Orthologyneuron part WBGene00006730
GO:0120025
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection WBGene00006730

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000608Ubiquitin-conjugating enzyme E2
IPR016135Ubiquitin-conjugating enzyme/RWD-like

No MapMan annotations defined for this gene.
KeggID Description
K10704UBE2V; ubiquitin-conjugating enzyme E2 variant
No chloroplast target sequence found.