Gene: ENSG00000221818 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000221818
Transcript Identifier
ENST00000520164
Gene Type
Coding gene
Location
8 : 25844609-26044859 : negative

Family Information

Homologous gene family
HOM02SEM013233
(6 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM010882
(6 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
early B-cell factor 2

Identifiers

Type Value
pidENSP00000430241
HGNC19090
UniprotQ9HAK2
RefSeq_mRNANM_022659.3
EMBLAC023566
EMBLAC090103
EMBLAK021562
EMBLAY700779
EMBLBC069665
EMBLBC069726
EMBLBC069747
EMBLBC069768
EMBLBC074794
EMBLBC113478
EMBLBC113504

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0060612
IEA
Genome Projectadipose tissue development
GO:0050873
IEA
Genome Projectbrown fat cell differentiation
GO:0045944
IEA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0035563
IEA
Genome Projectpositive regulation of chromatin binding
GO:0006366
IEA
Genome Projecttranscription by RNA polymerase II
GO:0001709
IEA
Genome Projectcell fate determination
GO:0120162
ISS
Gene Ontologypositive regulation of cold-induced thermogenesis1
GO:0035203
IEA
PLAZA Integrative Orthologyregulation of lamellocyte differentiation FBgn0001319
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death WBGene00006743
GO:0043065
IEA
PLAZA Integrative Orthologypositive regulation of apoptotic process WBGene00006743
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response FBgn0001319
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0001319
GO:0035171
IEA
PLAZA Integrative Orthologylamellocyte differentiation FBgn0001319
GO:0048468
IEA
PLAZA Integrative Orthologycell development WBGene00006743
GO:0035291
IEA
PLAZA Integrative Orthologyspecification of segmental identity, intercalary segment FBgn0001319
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0001319
GO:0035295
IEA
PLAZA Integrative Orthologytube development FBgn0001319
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction FBgn0001319
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0001319
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus FBgn0001319
GO:0048580
IEA
PLAZA Integrative Orthologyregulation of post-embryonic development FBgn0001319
GO:0045595
IEA
PLAZA Integrative Orthologyregulation of cell differentiation WBGene00006743
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0001319
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0001319
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0001319
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus FBgn0001319
GO:0009608
IEA
PLAZA Integrative Orthologyresponse to symbiont FBgn0001319
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0001319
GO:0050773
IEA
PLAZA Integrative Orthologyregulation of dendrite development FBgn0001319
GO:0048736
IEA
PLAZA Integrative Orthologyappendage development FBgn0001319
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0001319
GO:0048737
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage development FBgn0001319
GO:0048732
IEA
PLAZA Integrative Orthologygland development FBgn0001319
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0001319
GO:1902533
IEA
PLAZA Integrative Orthologypositive regulation of intracellular signal transduction FBgn0001319
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons WBGene00006743
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development WBGene00006743
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0001319
GO:1902531
IEA
PLAZA Integrative Orthologyregulation of intracellular signal transduction FBgn0001319
GO:0007154
IEA
PLAZA Integrative Orthologycell communication FBgn0001319
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0001319
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0001319
GO:0016204
IEA
PLAZA Integrative Orthologydetermination of muscle attachment site FBgn0001319
GO:0016203
IEA
PLAZA Integrative Orthologymuscle attachment FBgn0001319
GO:0050767
IEA
PLAZA Integrative Orthologyregulation of neurogenesis WBGene00006743
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis WBGene00006743
GO:0035107
IEA
PLAZA Integrative Orthologyappendage morphogenesis FBgn0001319
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization WBGene00006743
GO:0097696
IEA
PLAZA Integrative OrthologySTAT cascade FBgn0001319
GO:0046427
IEA
PLAZA Integrative Orthologypositive regulation of JAK-STAT cascade FBgn0001319
GO:0009887
IEA
PLAZA Integrative Orthologyanimal organ morphogenesis FBgn0001319
GO:0045613
IEA
PLAZA Integrative Orthologyregulation of plasmatocyte differentiation FBgn0001319
GO:0097065
IEA
PLAZA Integrative Orthologyanterior head development FBgn0001319
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process WBGene00006743
GO:0046425
IEA
PLAZA Integrative Orthologyregulation of JAK-STAT cascade FBgn0001319
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0001319
GO:0009886
IEA
PLAZA Integrative Orthologypost-embryonic animal morphogenesis FBgn0001319
GO:0045610
IEA
PLAZA Integrative Orthologyregulation of hemocyte differentiation FBgn0001319
GO:0009880
IEA
PLAZA Integrative Orthologyembryonic pattern specification FBgn0001319
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation WBGene00006743
GO:0048729
IEA
PLAZA Integrative Orthologytissue morphogenesis FBgn0001319
GO:0035114
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage morphogenesis FBgn0001319
GO:0010975
IEA
PLAZA Integrative Orthologyregulation of neuron projection development WBGene00006743
GO:0035239
IEA
PLAZA Integrative Orthologytube morphogenesis FBgn0001319
GO:0048563
IEA
PLAZA Integrative Orthologypost-embryonic animal organ morphogenesis FBgn0001319
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process WBGene00006743
GO:0051960
IEA
PLAZA Integrative Orthologyregulation of nervous system development WBGene00006743
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process FBgn0001319
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0001319
GO:0022603
IEA
PLAZA Integrative Orthologyregulation of anatomical structure morphogenesis FBgn0001319
GO:0002164
IEA
PLAZA Integrative Orthologylarval development WBGene00006743
GO:0042694
IEA
PLAZA Integrative Orthologymuscle cell fate specification FBgn0001319
GO:0042693
IEA
PLAZA Integrative Orthologymuscle cell fate commitment FBgn0001319
GO:0035120
IEA
PLAZA Integrative Orthologypost-embryonic appendage morphogenesis FBgn0001319
GO:1904894
IEA
PLAZA Integrative Orthologypositive regulation of STAT cascade FBgn0001319
GO:0060284
IEA
PLAZA Integrative Orthologyregulation of cell development WBGene00006743
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0001319
GO:0022604
IEA
PLAZA Integrative Orthologyregulation of cell morphogenesis FBgn0001319
GO:0060322
IEA
PLAZA Integrative Orthologyhead development FBgn0001319
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization WBGene00006743
GO:0060562
IEA
PLAZA Integrative Orthologyepithelial tube morphogenesis FBgn0001319
GO:0120035
IEA
PLAZA Integrative Orthologyregulation of plasma membrane bounded cell projection organization WBGene00006743
GO:1904892
IEA
PLAZA Integrative Orthologyregulation of STAT cascade FBgn0001319
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development WBGene00006743
GO:0010646
IEA
PLAZA Integrative Orthologyregulation of cell communication FBgn0001319
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus FBgn0001319
GO:0042692
IEA
PLAZA Integrative Orthologymuscle cell differentiation FBgn0001319
GO:0010647
IEA
PLAZA Integrative Orthologypositive regulation of cell communication FBgn0001319
GO:0010769
IEA
PLAZA Integrative Orthologyregulation of cell morphogenesis involved in differentiation FBgn0001319
GO:1903706
IEA
PLAZA Integrative Orthologyregulation of hemopoiesis FBgn0001319
GO:0007517
IEA
PLAZA Integrative Orthologymuscle organ development FBgn0001319
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress FBgn0001319
GO:0007525
IEA
PLAZA Integrative Orthologysomatic muscle development FBgn0001319
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0001319
GO:0007365
IEA
PLAZA Integrative Orthologyperiodic partitioning FBgn0001319
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development WBGene00006743
GO:0060538
IEA
PLAZA Integrative Orthologyskeletal muscle organ development FBgn0001319
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0001319
GO:0007367
IEA
PLAZA Integrative Orthologysegment polarity determination FBgn0001319
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development WBGene00006743
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0001319
GO:0040024
IEA
PLAZA Integrative Orthologydauer larval development WBGene00006743
GO:0016358
IEA
PLAZA Integrative Orthologydendrite development FBgn0001319
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0001319
GO:0048542
IEA
PLAZA Integrative Orthologylymph gland development FBgn0001319
GO:0048813
IEA
PLAZA Integrative Orthologydendrite morphogenesis FBgn0001319
GO:0048814
IEA
PLAZA Integrative Orthologyregulation of dendrite morphogenesis FBgn0001319
GO:0048534
IEA
PLAZA Integrative Orthologyhematopoietic or lymphoid organ development FBgn0001319
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development FBgn0001319
GO:0045664
IEA
PLAZA Integrative Orthologyregulation of neuron differentiation WBGene00006743
GO:0007474
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing vein specification FBgn0001319
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0001319
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0001319
GO:0007476
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing morphogenesis FBgn0001319
GO:0007350
IEA
PLAZA Integrative Orthologyblastoderm segmentation FBgn0001319
GO:0030097
IEA
PLAZA Integrative Orthologyhemopoiesis FBgn0001319
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0001319
GO:0007472
IEA
PLAZA Integrative Orthologywing disc morphogenesis FBgn0001319
GO:0010942
IEA
PLAZA Integrative Orthologypositive regulation of cell death WBGene00006743
GO:0031344
IEA
PLAZA Integrative Orthologyregulation of cell projection organization WBGene00006743
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death WBGene00006743
GO:0023052
IEA
PLAZA Integrative Orthologysignaling FBgn0001319
GO:0002009
IEA
PLAZA Integrative Orthologymorphogenesis of an epithelium FBgn0001319
GO:0023051
IEA
PLAZA Integrative Orthologyregulation of signaling FBgn0001319
GO:0007417
IEA
PLAZA Integrative Orthologycentral nervous system development FBgn0001319
GO:0023056
IEA
PLAZA Integrative Orthologypositive regulation of signaling FBgn0001319
GO:0007419
IEA
PLAZA Integrative Orthologyventral cord development FBgn0001319
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process FBgn0001319
GO:0009966
IEA
PLAZA Integrative Orthologyregulation of signal transduction FBgn0001319
GO:0009967
IEA
PLAZA Integrative Orthologypositive regulation of signal transduction FBgn0001319
GO:0042387
IEA
PLAZA Integrative Orthologyplasmatocyte differentiation FBgn0001319
GO:0042386
IEA
PLAZA Integrative Orthologyhemocyte differentiation FBgn0001319
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0001319
GO:0007267
IEA
PLAZA Integrative Orthologycell-cell signaling FBgn0001319
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0001319
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0001319
GO:0007380
IEA
PLAZA Integrative Orthologyspecification of segmental identity, head FBgn0001319
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization WBGene00006743
GO:0035556
IEA
PLAZA Integrative Orthologyintracellular signal transduction FBgn0001319
GO:0001708
IEA
PLAZA Integrative Orthologycell fate specification FBgn0001319
GO:0061061
IEA
PLAZA Integrative Orthologymuscle structure development FBgn0001319
GO:0002119
IEA
PLAZA Integrative Orthologynematode larval development WBGene00006743
GO:0001700
IEA
PLAZA Integrative Orthologyembryonic development via the syncytial blastoderm FBgn0001319
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response FBgn0001319
GO:0008219
IEA
PLAZA Integrative Orthologycell death WBGene00006743
GO:0007526
IEA
PLAZA Integrative Orthologylarval somatic muscle development FBgn0001319
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process WBGene00006743
GO:0002520
IEA
PLAZA Integrative Orthologyimmune system development FBgn0001319
GO:0007259
IEA
PLAZA Integrative OrthologyJAK-STAT cascade FBgn0001319
GO:0007379
IEA
PLAZA Integrative Orthologysegment specification FBgn0001319
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis WBGene00006743
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death WBGene00006743
GO:0043068
IEA
PLAZA Integrative Orthologypositive regulation of programmed cell death WBGene00006743
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization WBGene00006743
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development WBGene00006743
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching FBgn0001319
GO:0035282
IEA
PLAZA Integrative Orthologysegmentation FBgn0001319
GO:0035168
IEA
PLAZA Integrative Orthologylarval lymph gland hemocyte differentiation FBgn0001319
GO:0035289
IEA
PLAZA Integrative Orthologyposterior head segmentation FBgn0001319
GO:0035167
IEA
PLAZA Integrative Orthologylarval lymph gland hemopoiesis FBgn0001319
GO:0035288
IEA
PLAZA Integrative Orthologyanterior head segmentation FBgn0001319
GO:0035166
IEA
PLAZA Integrative Orthologypost-embryonic hemopoiesis FBgn0001319
GO:0035287
IEA
PLAZA Integrative Orthologyhead segmentation FBgn0001319
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0001319

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0000978
IEA
Genome ProjectRNA polymerase II proximal promoter sequence-specific DNA binding
GO:0000981
ISA
Gene OntologyDNA-binding transcription factor activity, RNA polymerase II-specific
GO:0019899
IEA
PLAZA Integrative Orthologyenzyme binding WBGene00006743
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding WBGene00006743
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000164330
GO:0035035
IEA
PLAZA Integrative Orthologyhistone acetyltransferase binding WBGene00006743

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0070013
IEA
PLAZA Integrative Orthologyintracellular organelle lumen WBGene00006743
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part WBGene00006743
GO:0044422
IEA
PLAZA Integrative Orthologyorganelle part WBGene00006743
GO:0044428
IEA
PLAZA Integrative Orthologynuclear part WBGene00006743
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin WBGene00006743
GO:0000785
IEA
PLAZA Integrative Orthologychromatin WBGene00006743
GO:0031974
IEA
PLAZA Integrative Orthologymembrane-enclosed lumen WBGene00006743
GO:0005694
IEA
PLAZA Integrative Orthologychromosome WBGene00006743
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part WBGene00006743
GO:0031981
IEA
PLAZA Integrative Orthologynuclear lumen WBGene00006743
GO:0044446
IEA
PLAZA Integrative Orthologyintracellular organelle part WBGene00006743
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle WBGene00006743
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome WBGene00006743
GO:0043233
IEA
PLAZA Integrative Orthologyorganelle lumen WBGene00006743
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle WBGene00006743

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002909IPT domain
IPR003523Transcription factor COE
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR018350Transcription factor COE, conserved site
IPR032200Transcription factor COE, DNA-binding domain
IPR032201Transcription factor COE, helix-loop-helix domain

No MapMan annotations defined for this gene.
KeggID Description
K09103EBF, COE; early B-cell factor
No chloroplast target sequence found.