Gene: ENSG00000187140 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000187140
Transcript Identifier
ENST00000371116
Gene Type
Coding gene
Location
1 : 63323059-63324495 : positive

Family Information

Homologous gene family
HOM02SEM000449
(82 genes in 6 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
forkhead box D3

Identifiers

Type Value
pidENSP00000360157
HGNC3804
UniprotQ9UJU5
RefSeq_mRNANM_012183.2
EMBLAF197560
EMBLAL049636
EMBLL12142

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045944
IDA
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IDA
Gene Ontologypositive regulation of transcription by RNA polymerase II1
GO:0035019
TAS
Genome Projectsomatic stem cell population maintenance
GO:0035019
TAS
Gene Ontologysomatic stem cell population maintenance
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0001701
ISS
Genome Projectin utero embryonic development
GO:0001701
ISS
Gene Ontologyin utero embryonic development
GO:0000122
IDA
ISS
Genome Projectnegative regulation of transcription by RNA polymerase II
GO:0000122
IDA
ISS
Gene Ontologynegative regulation of transcription by RNA polymerase II2
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process ENSG00000186790
GO:0012501
IEA
PLAZA Integrative Orthologyprogrammed cell death ENSG00000186790
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process ENSG00000129654
GO:0034599
IEA
PLAZA Integrative Orthologycellular response to oxidative stress YCR065W
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation ENSG00000129654
GO:0043066
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic process ENSG00000186790
GO:0072310
IEA
PLAZA Integrative Orthologyglomerular epithelial cell development ENSG00000129654
GO:0072311
IEA
PLAZA Integrative Orthologyglomerular epithelial cell differentiation ENSG00000129654
GO:0051235
IEA
PLAZA Integrative Orthologymaintenance of location WBGene00006853
GO:0042127
IEA
PLAZA Integrative Orthologyregulation of cell proliferation ENSG00000186790
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction ENSG00000137273
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process ENSG00000129654
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle YCR065W
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization YCR065W
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth WBGene00006853
GO:0048468
IEA
PLAZA Integrative Orthologycell development ENSG00000129654
GO:0045597
IEA
PLAZA Integrative Orthologypositive regulation of cell differentiation ENSG00000129654
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process ENSG00000137273
GO:0035295
IEA
PLAZA Integrative Orthologytube development ENSG00000129654
GO:0061141
IEA
PLAZA Integrative Orthologylung ciliated cell differentiation ENSG00000129654
GO:0035850
IEA
PLAZA Integrative Orthologyepithelial cell differentiation involved in kidney development ENSG00000129654
GO:0030324
IEA
PLAZA Integrative Orthologylung development ENSG00000129654
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus YCR065W
GO:0030323
IEA
PLAZA Integrative Orthologyrespiratory tube development ENSG00000129654
GO:0033036
IEA
PLAZA Integrative Orthologymacromolecule localization WBGene00006853
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress YCR065W
GO:0048588
IEA
PLAZA Integrative Orthologydevelopmental cell growth WBGene00006853
GO:0045595
IEA
PLAZA Integrative Orthologyregulation of cell differentiation ENSG00000129654
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis WBGene00006853
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus WBGene00006853
GO:0007548
IEA
PLAZA Integrative Orthologysex differentiation ENSG00000137273
GO:0072163
IEA
PLAZA Integrative Orthologymesonephric epithelium development ENSG00000129654
GO:0072164
IEA
PLAZA Integrative Orthologymesonephric tubule development ENSG00000129654
GO:0006979
IEA
PLAZA Integrative Orthologyresponse to oxidative stress YCR065W
GO:0062009
IEA
PLAZA Integrative Orthologysecondary palate development ENSG00000178919
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis WBGene00006853
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons WBGene00006853
GO:0048732
IEA
PLAZA Integrative Orthologygland development ENSG00000178919
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development WBGene00006853
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis WBGene00006853
GO:0090598
IEA
PLAZA Integrative Orthologymale anatomical structure morphogenesis WBGene00006853
GO:0009299
IEA
PLAZA Integrative OrthologymRNA transcription ENSG00000186790
GO:0060465
IEA
PLAZA Integrative Orthologypharynx development ENSG00000178919
GO:0035502
IEA
PLAZA Integrative Orthologymetanephric part of ureteric bud development ENSG00000129654
GO:0016049
IEA
PLAZA Integrative Orthologycell growth WBGene00006853
GO:0072016
IEA
PLAZA Integrative Orthologyglomerular parietal epithelial cell development ENSG00000129654
GO:0031023
IEA
PLAZA Integrative Orthologymicrotubule organizing center organization YCR065W
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis YCR065W
GO:0072139
IEA
PLAZA Integrative Orthologyglomerular parietal epithelial cell differentiation ENSG00000129654
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization YCR065W
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component WBGene00006853
GO:0030858
IEA
PLAZA Integrative Orthologypositive regulation of epithelial cell differentiation ENSG00000129654
GO:0048731
IEA
PLAZA Integrative Orthologysystem development ENSG00000129654
GO:0051179
IEA
PLAZA Integrative Orthologylocalization WBGene00006853
GO:0030856
IEA
PLAZA Integrative Orthologyregulation of epithelial cell differentiation ENSG00000129654
GO:0045185
IEA
PLAZA Integrative Orthologymaintenance of protein location WBGene00006853
GO:0072010
IEA
PLAZA Integrative Orthologyglomerular epithelium development ENSG00000129654
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation ENSG00000129654
GO:0048846
IEA
PLAZA Integrative Orthologyaxon extension involved in axon guidance WBGene00006853
GO:0009887
IEA
PLAZA Integrative Orthologyanimal organ morphogenesis ENSG00000129654
GO:0009888
IEA
PLAZA Integrative Orthologytissue development ENSG00000129654
GO:0061005
IEA
PLAZA Integrative Orthologycell differentiation involved in kidney development ENSG00000129654
GO:0042981
IEA
PLAZA Integrative Orthologyregulation of apoptotic process ENSG00000186790
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical YCR065W
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation WBGene00006853
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development ENSG00000137273
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus YCR065W
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle ENSG00000186790
GO:0055123
IEA
PLAZA Integrative Orthologydigestive system development ENSG00000178919
GO:0046661
IEA
PLAZA Integrative Orthologymale sex differentiation WBGene00006853
GO:0006915
IEA
PLAZA Integrative Orthologyapoptotic process ENSG00000186790
GO:0048565
IEA
PLAZA Integrative Orthologydigestive tract development ENSG00000178919
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction ENSG00000137273
GO:0097166
IEA
PLAZA Integrative Orthologylens epithelial cell proliferation ENSG00000186790
GO:0042330
IEA
PLAZA Integrative Orthologytaxis WBGene00006853
GO:0060560
IEA
PLAZA Integrative Orthologydevelopmental growth involved in morphogenesis WBGene00006853
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis WBGene00006853
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization WBGene00006853
GO:0007050
IEA
PLAZA Integrative Orthologycell cycle arrest ENSG00000186790
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development ENSG00000129654
GO:2001111
IEA
PLAZA Integrative Orthologypositive regulation of lens epithelial cell proliferation ENSG00000186790
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus YCR065W
GO:0048675
IEA
PLAZA Integrative Orthologyaxon extension WBGene00006853
GO:0001657
IEA
PLAZA Integrative Orthologyureteric bud development ENSG00000129654
GO:0001656
IEA
PLAZA Integrative Orthologymetanephros development ENSG00000129654
GO:0030878
IEA
PLAZA Integrative Orthologythyroid gland development ENSG00000178919
GO:0001655
IEA
PLAZA Integrative Orthologyurogenital system development ENSG00000129654
GO:0001654
IEA
PLAZA Integrative Orthologyeye development ENSG00000186790
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress YCR065W
GO:0007005
IEA
PLAZA Integrative Orthologymitochondrion organization YCR065W
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development WBGene00006853
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation WBGene00006853
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development WBGene00006853
GO:0072009
IEA
PLAZA Integrative Orthologynephron epithelium development ENSG00000129654
GO:0072006
IEA
PLAZA Integrative Orthologynephron development ENSG00000129654
GO:0043010
IEA
PLAZA Integrative Orthologycamera-type eye development ENSG00000186790
GO:0072001
IEA
PLAZA Integrative Orthologyrenal system development ENSG00000129654
GO:2001109
IEA
PLAZA Integrative Orthologyregulation of lens epithelial cell proliferation ENSG00000186790
GO:0071157
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle arrest ENSG00000186790
GO:0071156
IEA
PLAZA Integrative Orthologyregulation of cell cycle arrest ENSG00000186790
GO:0016071
IEA
PLAZA Integrative OrthologymRNA metabolic process ENSG00000186790
GO:0051300
IEA
PLAZA Integrative Orthologyspindle pole body organization YCR065W
GO:0006935
IEA
PLAZA Integrative Orthologychemotaxis WBGene00006853
GO:0048538
IEA
PLAZA Integrative Orthologythymus development ENSG00000178919
GO:0048534
IEA
PLAZA Integrative Orthologyhematopoietic or lymphoid organ development ENSG00000178919
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development ENSG00000129654
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development ENSG00000129654
GO:0060428
IEA
PLAZA Integrative Orthologylung epithelium development ENSG00000129654
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis ENSG00000129654
GO:1901248
IEA
PLAZA Integrative Orthologypositive regulation of lung ciliated cell differentiation ENSG00000129654
GO:0060548
IEA
PLAZA Integrative Orthologynegative regulation of cell death ENSG00000186790
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle ENSG00000186790
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis WBGene00006853
GO:0045786
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle ENSG00000186790
GO:1901246
IEA
PLAZA Integrative Orthologyregulation of lung ciliated cell differentiation ENSG00000129654
GO:0008284
IEA
PLAZA Integrative Orthologypositive regulation of cell proliferation ENSG00000186790
GO:0060021
IEA
PLAZA Integrative Orthologyroof of mouth development ENSG00000178919
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion WBGene00006853
GO:0060541
IEA
PLAZA Integrative Orthologyrespiratory system development ENSG00000129654
GO:0060023
IEA
PLAZA Integrative Orthologysoft palate development ENSG00000178919
GO:0008283
IEA
PLAZA Integrative Orthologycell proliferation ENSG00000186790
GO:0060022
IEA
PLAZA Integrative Orthologyhard palate development ENSG00000178919
GO:0010941
IEA
PLAZA Integrative Orthologyregulation of cell death ENSG00000186790
GO:1990138
IEA
PLAZA Integrative Orthologyneuron projection extension WBGene00006853
GO:0150063
IEA
PLAZA Integrative Orthologyvisual system development ENSG00000186790
GO:0032835
IEA
PLAZA Integrative Orthologyglomerulus development ENSG00000129654
GO:0003338
IEA
PLAZA Integrative Orthologymetanephros morphogenesis ENSG00000129654
GO:0010948
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle process ENSG00000186790
GO:0040007
IEA
PLAZA Integrative Orthologygrowth WBGene00006853
GO:0007423
IEA
PLAZA Integrative Orthologysensory organ development ENSG00000186790
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000178919
GO:0060479
IEA
PLAZA Integrative Orthologylung cell differentiation ENSG00000129654
GO:0035270
IEA
PLAZA Integrative Orthologyendocrine system development ENSG00000178919
GO:0000226
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization YCR065W
GO:0045138
IEA
PLAZA Integrative Orthologynematode male tail tip morphogenesis WBGene00006853
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis WBGene00006853
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation WBGene00006853
GO:0048806
IEA
PLAZA Integrative Orthologygenitalia development ENSG00000137273
GO:0060993
IEA
PLAZA Integrative Orthologykidney morphogenesis ENSG00000129654
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development WBGene00006853
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality WBGene00006853
GO:1902284
IEA
PLAZA Integrative Orthologyneuron projection extension involved in neuron projection guidance WBGene00006853
GO:0042789
IEA
PLAZA Integrative OrthologymRNA transcription by RNA polymerase II ENSG00000186790
GO:0050679
IEA
PLAZA Integrative Orthologypositive regulation of epithelial cell proliferation ENSG00000186790
GO:0050678
IEA
PLAZA Integrative Orthologyregulation of epithelial cell proliferation ENSG00000186790
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis WBGene00006853
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process ENSG00000129654
GO:0001823
IEA
PLAZA Integrative Orthologymesonephros development ENSG00000129654
GO:0001822
IEA
PLAZA Integrative Orthologykidney development ENSG00000129654
GO:0050673
IEA
PLAZA Integrative Orthologyepithelial cell proliferation ENSG00000186790
GO:0008219
IEA
PLAZA Integrative Orthologycell death ENSG00000186790
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process ENSG00000129654
GO:0048880
IEA
PLAZA Integrative Orthologysensory system development ENSG00000186790
GO:0097485
IEA
PLAZA Integrative Orthologyneuron projection guidance WBGene00006853
GO:0002520
IEA
PLAZA Integrative Orthologyimmune system development ENSG00000178919
GO:0007017
IEA
PLAZA Integrative Orthologymicrotubule-based process YCR065W
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development ENSG00000137273
GO:0002088
IEA
PLAZA Integrative Orthologylens development in camera-type eye ENSG00000186790
GO:0072073
IEA
PLAZA Integrative Orthologykidney epithelium development ENSG00000129654
GO:0043069
IEA
PLAZA Integrative Orthologynegative regulation of programmed cell death ENSG00000186790
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process ENSG00000129654
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis WBGene00006853
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development ENSG00000129654
GO:0007411
IEA
PLAZA Integrative Orthologyaxon guidance WBGene00006853
GO:0043067
IEA
PLAZA Integrative Orthologyregulation of programmed cell death ENSG00000186790
GO:0008104
IEA
PLAZA Integrative Orthologyprotein localization WBGene00006853
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process YCR065W
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization WBGene00006853
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization YCR065W
GO:0060487
IEA
PLAZA Integrative Orthologylung epithelial cell differentiation ENSG00000129654

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1
GO:0003700
ISS
Genome ProjectDNA-binding transcription factor activity
GO:0003700
ISS
Gene OntologyDNA-binding transcription factor activity
GO:0001227
IDA
Genome ProjectDNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001227
IDA
Gene OntologyDNA-binding transcription repressor activity, RNA polymerase II-specific2
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000977
IDA
Gene OntologyRNA polymerase II regulatory region sequence-specific DNA binding2
GO:0000981
ISA, ISM
NAS
Gene OntologyDNA-binding transcription factor activity, RNA polymerase II-specific3
GO:0008134
IEA
PLAZA Integrative Orthologytranscription factor binding ENSG00000137273
GO:0001228
IEA
PLAZA Integrative OrthologyDNA-binding transcription activator activity, RNA polymerase II-specific ENSG00000137273
GO:0008301
IEA
PLAZA Integrative OrthologyDNA binding, bending ENSG00000251493
GO:0003714
IEA
PLAZA Integrative Orthologytranscription corepressor activity WBGene00006853
GO:0003712
IEA
PLAZA Integrative Orthologytranscription coregulator activity WBGene00006853

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0000790
IDA
Gene Ontologynuclear chromatin2
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex ENSG00000137273
GO:0005667
IEA
PLAZA Integrative Orthologytranscription factor complex ENSG00000137273
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm YCR065W

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001766Fork head domain
IPR011991ArsR-like helix-turn-helix domain
IPR018122Fork head domain conserved site1
IPR030456Fork head domain conserved site 2

No MapMan annotations defined for this gene.
KeggID Description
K09397FOXD; forkhead box protein D
No chloroplast target sequence found.