Gene: ENSG00000179051 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000179051
Transcript Identifier
ENST00000375433
Gene Type
Coding gene
Location
1 : 17409090-17438514 : negative

Family Information

Homologous gene family
HOM02SEM000062
(306 genes in 26 species)
specific family

Descriptions

gene_descr
regulator of chromosome condensation 2

Identifiers

Type Value
pidENSP00000364582
HGNC30297
UniprotQ9P258
UniprotA0A024RAC5
RefSeq_mRNANM_001136204.2
EMBLCH471134

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1900027
IEA
Genome Projectregulation of ruffle assembly
GO:1900025
ISS
Genome Projectnegative regulation of substrate adhesion-dependent cell spreading
GO:1900025
ISS
Gene Ontologynegative regulation of substrate adhesion-dependent cell spreading
GO:0090630
IEA
Genome Projectactivation of GTPase activity
GO:0072356
IMP
Genome Projectchromosome passenger complex localization to kinetochore
GO:0072356
IMP
Gene Ontologychromosome passenger complex localization to kinetochore1
GO:0051987
IMP
Genome Projectpositive regulation of attachment of spindle microtubules to kinetochore
GO:0051987
IMP
Gene Ontologypositive regulation of attachment of spindle microtubules to kinetochore1
GO:0051895
ISS
Genome Projectnegative regulation of focal adhesion assembly
GO:0051895
ISS
Gene Ontologynegative regulation of focal adhesion assembly
GO:0051301
IEA
Genome Projectcell division
GO:0048041
IDA
Genome Projectfocal adhesion assembly
GO:0048041
IDA
Gene Ontologyfocal adhesion assembly2
GO:0045184
IEA
Genome Projectestablishment of protein localization
GO:0034260
IMP
ISS
Genome Projectnegative regulation of GTPase activity
GO:0034260
IMP
ISS
Gene Ontologynegative regulation of GTPase activity3
GO:0030334
ISS
Genome Projectregulation of cell migration
GO:0030334
ISS
Gene Ontologyregulation of cell migration
GO:0010971
IMP
Genome Projectpositive regulation of G2/M transition of mitotic cell cycle
GO:0010971
IMP
Gene Ontologypositive regulation of G2/M transition of mitotic cell cycle1
GO:0010762
IEA
Genome Projectregulation of fibroblast migration
GO:0007229
IDA
Genome Projectintegrin-mediated signaling pathway
GO:0007229
IDA
Gene Ontologyintegrin-mediated signaling pathway2
GO:0007062
TAS
Genome Projectsister chromatid cohesion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048365
IPI
Genome ProjectRac GTPase binding
GO:0048365
IPI
Gene OntologyRac GTPase binding1
GO:0031267
IPI
Genome Projectsmall GTPase binding
GO:0031267
IPI
Gene Ontologysmall GTPase binding3
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0019904
IPI
Gene Ontologyprotein domain specific binding3
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0019901
IPI
Gene Ontologyprotein kinase binding3
GO:0008017
IMP
Genome Projectmicrotubule binding
GO:0008017
IMP
Gene Ontologymicrotubule binding1
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4
GO:0003723
IDA
Genome ProjectRNA binding
GO:0003723
Gene OntologyRNA binding5 6

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IDA
Genome Projectmembrane
GO:0016020
IDA
Gene Ontologymembrane3
GO:1990023
IDA
Genome Projectmitotic spindle midzone
GO:1990023
IDA
Gene Ontologymitotic spindle midzone1
GO:0034506
IDA
Genome Projectchromosome, centromeric core domain
GO:0034506
IDA
Gene Ontologychromosome, centromeric core domain1
GO:0031901
IEA
Genome Projectearly endosome membrane
GO:0030496
IDA
Genome Projectmidbody
GO:0030496
IDA
Gene Ontologymidbody1
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005730
IEA
Genome Projectnucleolus
GO:0005875
IEA
PLAZA Integrative Orthologymicrotubule associated complex FBgn0031769
GO:0032991
IEA
PLAZA Integrative Orthologyprotein-containing complex FBgn0031769

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000408Regulator of chromosome condensation, RCC1
IPR009091Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.