Gene: ENSG00000177076 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000177076
Transcript Identifier
ENST00000340967
Gene Type
Coding gene
Location
9 : 19409085-19450636 : positive

Family Information

Homologous gene family
HOM02SEM019571
(4 genes in 3 species)
specific family

Descriptions

gene_descr
alkaline ceramidase 2

Identifiers

Type Value
pidENSP00000342609
HGNC23675
UniprotQ5QJU3
RefSeq_mRNANM_001010887.2
EMBLCHEMBL2331067
EMBLAF370405
EMBLAL158206
EMBLAL391834
EMBLAY312516
EMBLBC092487

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0090285
IMP
Genome Projectnegative regulation of protein glycosylation in Golgi
GO:0090285
IMP
Gene Ontologynegative regulation of protein glycosylation in Golgi1
GO:0046512
IDA
Genome Projectsphingosine biosynthetic process
GO:0046512
IDA
Gene Ontologysphingosine biosynthetic process1 2 3
GO:0035690
IEP
Genome Projectcellular response to drug
GO:0035690
IEP
Gene Ontologycellular response to drug3
GO:0033629
IDA
Genome Projectnegative regulation of cell adhesion mediated by integrin
GO:0033629
IDA
Gene Ontologynegative regulation of cell adhesion mediated by integrin4
GO:0032526
IDA
Genome Projectresponse to retinoic acid
GO:0032526
IDA
Gene Ontologyresponse to retinoic acid4
GO:0030148
TAS
Genome Projectsphingolipid biosynthetic process
GO:0030148
TAS
Gene Ontologysphingolipid biosynthetic process
GO:0010942
IMP
Genome Projectpositive regulation of cell death
GO:0010942
IMP
Gene Ontologypositive regulation of cell death3
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008284
IDA
Gene Ontologypositive regulation of cell proliferation2
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919
IMP
Gene Ontologyactivation of cysteine-type endopeptidase activity involved in apoptotic process3
GO:0006672
IEA
Genome Projectceramide metabolic process
GO:0001953
IDA
Genome Projectnegative regulation of cell-matrix adhesion
GO:0001953
IDA
Gene Ontologynegative regulation of cell-matrix adhesion4
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0045064
GO:0030149
IEA
PLAZA Integrative Orthologysphingolipid catabolic process FBgn0045064
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0045064
GO:0016042
IEA
PLAZA Integrative Orthologylipid catabolic process FBgn0045064
GO:0044242
IEA
PLAZA Integrative Orthologycellular lipid catabolic process FBgn0045064
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0045064
GO:0007417
IEA
PLAZA Integrative Orthologycentral nervous system development FBgn0045064
GO:0046514
IEA
PLAZA Integrative Orthologyceramide catabolic process FBgn0045064
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process FBgn0045064
GO:0007420
IEA
PLAZA Integrative Orthologybrain development FBgn0045064
GO:0046466
IEA
PLAZA Integrative Orthologymembrane lipid catabolic process FBgn0045064
GO:0048513
IEA
PLAZA Integrative Orthologyanimal organ development FBgn0045064
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process FBgn0045064
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process FBgn0045064
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0045064
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0045064
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process FBgn0045064
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0045064
GO:0060322
IEA
PLAZA Integrative Orthologyhead development FBgn0045064

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071633
IDA
Genome Projectdihydroceramidase activity
GO:0071633
IDA
Gene Ontologydihydroceramidase activity3
GO:0017040
IDA
TAS
Genome ProjectN-acylsphingosine amidohydrolase activity
GO:0017040
IDA
TAS
Gene OntologyN-acylsphingosine amidohydrolase activity1 2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030173
IDA
Genome Projectintegral component of Golgi membrane
GO:0030173
IDA
Gene Ontologyintegral component of Golgi membrane1
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus2
GO:0000139
TAS
Genome ProjectGolgi membrane
GO:0000139
TAS
Gene OntologyGolgi membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR008901Ceramidase

No MapMan annotations defined for this gene.
KeggID Description
K01441ACER1_2, ASAH3; alkaline ceramidase
No chloroplast target sequence found.