Gene: ENSG00000176994 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000176994
Transcript Identifier
ENST00000406438
Gene Type
Coding gene
Location
17 : 18315790-18323070 : positive

Family Information

Homologous gene family
HOM02SEM045660
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Smith-Magenis syndrome chromosome region, candidate 8

Identifiers

Type Value
pidENSP00000385025
HGNC17921
UniprotQ8TEV9
RefSeq_mRNANM_144775.2
EMBLAF467440
EMBLBC001018
EMBLBC014179
EMBLBC101116
EMBLBC101117
EMBLBC142680

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1903432
IMP
Genome Projectregulation of TORC1 signaling
GO:1903432
IMP
Gene Ontologyregulation of TORC1 signaling1
GO:1902902
IMP
Genome Projectnegative regulation of autophagosome assembly
GO:1902902
IMP
Gene Ontologynegative regulation of autophagosome assembly2
GO:1901098
IMP
Genome Projectpositive regulation of autophagosome maturation
GO:1901098
IMP
Gene Ontologypositive regulation of autophagosome maturation2
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0032008
IMP
Genome Projectpositive regulation of TOR signaling
GO:0032008
IMP
Gene Ontologypositive regulation of TOR signaling2
GO:0016242
IMP
Genome Projectnegative regulation of macroautophagy
GO:0016242
IMP
Gene Ontologynegative regulation of macroautophagy2
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010629
IMP
Gene Ontologynegative regulation of gene expression2
GO:0010506
IMP
Genome Projectregulation of autophagy
GO:0010506
IMP
Gene Ontologyregulation of autophagy3
GO:0006914
IEA
Genome Projectautophagy
GO:0006469
IMP
Genome Projectnegative regulation of protein kinase activity
GO:0006469
IMP
Gene Ontologynegative regulation of protein kinase activity2
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006351
IEA
Genome Projecttranscription, DNA-templated

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0017112
IDA
Genome ProjectRab guanyl-nucleotide exchange factor activity
GO:0017112
IDA
Gene OntologyRab guanyl-nucleotide exchange factor activity3 4
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0019901
IPI
Gene Ontologyprotein kinase binding3
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 5
GO:0004860
IMP
Genome Projectprotein kinase inhibitor activity
GO:0004860
IMP
Gene Ontologyprotein kinase inhibitor activity2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990316
IDA
Genome ProjectAtg1/ULK1 kinase complex
GO:1990316
IDA
Gene OntologyAtg1/ULK1 kinase complex2 6
GO:0032045
IDA
Genome Projectguanyl-nucleotide exchange factor complex
GO:0032045
IDA
Gene Ontologyguanyl-nucleotide exchange factor complex3
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm2 6
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm2
GO:0000785
IDA
Genome Projectchromatin
GO:0000785
IDA
Gene Ontologychromatin2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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No InterPro domains detected for this gene.
No MapMan annotations defined for this gene.
No Kegg annotations defined for this gene.
No chloroplast target sequence found.