Gene: ENSG00000175203 (Homo sapiens)

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Gene Identifier
ENSG00000175203
Transcript Identifier
ENST00000434715
Gene Type
Coding gene
Location
12 : 57530689-57547063 : negative

Family Information

Homologous gene family
HOM02SEM019503
(4 genes in 4 species)
specific family
Orthologous gene family
ORTHO02SEM014053
(4 genes in 4 species)
specific family

Descriptions

gene_descr
dynactin 2 (p50)

Identifiers

Type Value
pidENSP00000408910
HGNC2712
UniprotQ13561
UniprotV9HW58
RefSeq_mRNANM_006400.4
EMBLFJ224315

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097711
TAS
Genome Projectciliary basal body-plasma membrane docking
GO:0097711
TAS
Gene Ontologyciliary basal body-plasma membrane docking
GO:0071539
IMP
Genome Projectprotein localization to centrosome
GO:0071539
IMP
Gene Ontologyprotein localization to centrosome1
GO:0032402
IEA
Genome Projectmelanosome transport
GO:0019886
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019886
TAS
Gene Ontologyantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0008283
IMP
Genome Projectcell proliferation
GO:0008283
IMP
Gene Ontologycell proliferation2
GO:0007052
IBA
Genome Projectmitotic spindle organization
GO:0006888
TAS
Genome ProjectER to Golgi vesicle-mediated transport
GO:0006888
TAS
Gene OntologyER to Golgi vesicle-mediated transport
GO:0000278
IMP
Genome Projectmitotic cell cycle
GO:0000278
IMP
Gene Ontologymitotic cell cycle2
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000086
TAS
Gene OntologyG2/M transition of mitotic cell cycle
GO:0010389
TAS
Gene Ontologyregulation of G2/M transition of mitotic cell cycle
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0021825
GO:0035282
IEA
PLAZA Integrative Orthologysegmentation FBgn0021825
GO:0009314
IEA
PLAZA Integrative Orthologyresponse to radiation FBgn0021825
GO:0009798
IEA
PLAZA Integrative Orthologyaxis specification FBgn0021825
GO:0009952
IEA
PLAZA Integrative Orthologyanterior/posterior pattern specification FBgn0021825
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0021825
GO:0000578
IEA
PLAZA Integrative Orthologyembryonic axis specification FBgn0021825
GO:0007018
IEA
PLAZA Integrative Orthologymicrotubule-based movement FBgn0021825
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process FBgn0021825
GO:0060249
IEA
PLAZA Integrative Orthologyanatomical structure homeostasis FBgn0021825
GO:0072583
IEA
PLAZA Integrative Orthologyclathrin-dependent endocytosis FBgn0021825
GO:0051642
IEA
PLAZA Integrative Orthologycentrosome localization FBgn0021825
GO:0009948
IEA
PLAZA Integrative Orthologyanterior/posterior axis specification FBgn0021825
GO:0030705
IEA
PLAZA Integrative Orthologycytoskeleton-dependent intracellular transport FBgn0021825
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process FBgn0021825
GO:0045494
IEA
PLAZA Integrative Orthologyphotoreceptor cell maintenance FBgn0021825
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality FBgn0021825
GO:0008595
IEA
PLAZA Integrative Orthologyanterior/posterior axis specification, embryo FBgn0021825
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0021825
GO:0021700
IEA
PLAZA Integrative Orthologydevelopmental maturation FBgn0021825
GO:0061842
IEA
PLAZA Integrative Orthologymicrotubule organizing center localization FBgn0021825
GO:0060632
IEA
PLAZA Integrative Orthologyregulation of microtubule-based movement FBgn0021825
GO:0007028
IEA
PLAZA Integrative Orthologycytoplasm organization FBgn0021825
GO:0008358
IEA
PLAZA Integrative Orthologymaternal determination of anterior/posterior axis, embryo FBgn0021825
GO:0023052
IEA
PLAZA Integrative Orthologysignaling FBgn0021825
GO:0007351
IEA
PLAZA Integrative Orthologytripartite regional subdivision FBgn0021825
GO:0007350
IEA
PLAZA Integrative Orthologyblastoderm segmentation FBgn0021825
GO:0051272
IEA
PLAZA Integrative Orthologypositive regulation of cellular component movement FBgn0021825
GO:0051270
IEA
PLAZA Integrative Orthologyregulation of cellular component movement FBgn0021825
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus FBgn0021825
GO:0032388
IEA
PLAZA Integrative Orthologypositive regulation of intracellular transport FBgn0021825
GO:0032386
IEA
PLAZA Integrative Orthologyregulation of intracellular transport FBgn0021825
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0021825
GO:0051028
IEA
PLAZA Integrative OrthologymRNA transport FBgn0021825
GO:0071705
IEA
PLAZA Integrative Orthologynitrogen compound transport FBgn0021825
GO:0008298
IEA
PLAZA Integrative Orthologyintracellular mRNA localization FBgn0021825
GO:0060811
IEA
PLAZA Integrative Orthologyintracellular mRNA localization involved in anterior/posterior axis specification FBgn0021825
GO:0060810
IEA
PLAZA Integrative Orthologyintracellular mRNA localization involved in pattern specification process FBgn0021825
GO:0001894
IEA
PLAZA Integrative Orthologytissue homeostasis FBgn0021825
GO:0001895
IEA
PLAZA Integrative Orthologyretina homeostasis FBgn0021825
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus FBgn0021825
GO:0015931
IEA
PLAZA Integrative Orthologynucleobase-containing compound transport FBgn0021825
GO:0071702
IEA
PLAZA Integrative Orthologyorganic substance transport FBgn0021825
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0021825
GO:0007296
IEA
PLAZA Integrative Orthologyvitellogenesis FBgn0021825
GO:0009994
IEA
PLAZA Integrative Orthologyoocyte differentiation FBgn0021825
GO:0051050
IEA
PLAZA Integrative Orthologypositive regulation of transport FBgn0021825
GO:0006403
IEA
PLAZA Integrative OrthologyRNA localization FBgn0021825
GO:0099111
IEA
PLAZA Integrative Orthologymicrotubule-based transport FBgn0021825
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0021825
GO:0051049
IEA
PLAZA Integrative Orthologyregulation of transport FBgn0021825
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus FBgn0021825
GO:0098657
IEA
PLAZA Integrative Orthologyimport into cell FBgn0021825
GO:0045451
IEA
PLAZA Integrative Orthologypole plasm oskar mRNA localization FBgn0021825
GO:0098930
IEA
PLAZA Integrative Orthologyaxonal transport FBgn0021825
GO:0051606
IEA
PLAZA Integrative Orthologydetection of stimulus FBgn0021825
GO:0010970
IEA
PLAZA Integrative Orthologytransport along microtubule FBgn0021825
GO:0032886
IEA
PLAZA Integrative Orthologyregulation of microtubule-based process FBgn0021825
GO:0061883
IEA
PLAZA Integrative Orthologyclathrin-dependent endocytosis involved in vitellogenesis FBgn0021825
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0021825
GO:0009880
IEA
PLAZA Integrative Orthologyembryonic pattern specification FBgn0021825
GO:0006897
IEA
PLAZA Integrative Orthologyendocytosis FBgn0021825
GO:0006898
IEA
PLAZA Integrative Orthologyreceptor-mediated endocytosis FBgn0021825
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization FBgn0021825
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0021825
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component FBgn0021825
GO:0042592
IEA
PLAZA Integrative Orthologyhomeostatic process FBgn0021825
GO:2001017
IEA
PLAZA Integrative Orthologyregulation of retrograde axon cargo transport FBgn0021825
GO:2001019
IEA
PLAZA Integrative Orthologypositive regulation of retrograde axon cargo transport FBgn0021825
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0021825
GO:0016325
IEA
PLAZA Integrative Orthologyoocyte microtubule cytoskeleton organization FBgn0021825
GO:0060341
IEA
PLAZA Integrative Orthologyregulation of cellular localization FBgn0021825
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0021825
GO:0007154
IEA
PLAZA Integrative Orthologycell communication FBgn0021825
GO:0008088
IEA
PLAZA Integrative Orthologyaxo-dendritic transport FBgn0021825
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0021825
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0021825
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0021825
GO:0007315
IEA
PLAZA Integrative Orthologypole plasm assembly FBgn0021825
GO:0007316
IEA
PLAZA Integrative Orthologypole plasm RNA localization FBgn0021825
GO:0007314
IEA
PLAZA Integrative Orthologyoocyte anterior/posterior axis specification FBgn0021825
GO:0007308
IEA
PLAZA Integrative Orthologyoocyte construction FBgn0021825
GO:0007309
IEA
PLAZA Integrative Orthologyoocyte axis specification FBgn0021825
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0021825
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0021825
GO:0050658
IEA
PLAZA Integrative OrthologyRNA transport FBgn0021825
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0021825
GO:0050657
IEA
PLAZA Integrative Orthologynucleic acid transport FBgn0021825
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus FBgn0021825
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0021825
GO:0009581
IEA
PLAZA Integrative Orthologydetection of external stimulus FBgn0021825
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0021825
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0021825
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction FBgn0021825
GO:0009583
IEA
PLAZA Integrative Orthologydetection of light stimulus FBgn0021825
GO:0009582
IEA
PLAZA Integrative Orthologydetection of abiotic stimulus FBgn0021825
GO:0007163
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cell polarity FBgn0021825
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process FBgn0021825
GO:0048469
IEA
PLAZA Integrative Orthologycell maturation FBgn0021825
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0021825
GO:0007602
IEA
PLAZA Integrative Orthologyphototransduction FBgn0021825
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0021825
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction FBgn0021825
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0021825
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0021825
GO:0019094
IEA
PLAZA Integrative Orthologypole plasm mRNA localization FBgn0021825
GO:0051236
IEA
PLAZA Integrative Orthologyestablishment of RNA localization FBgn0021825
GO:0048599
IEA
PLAZA Integrative Orthologyoocyte development FBgn0021825
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0021825
GO:0048871
IEA
PLAZA Integrative Orthologymulticellular organismal homeostasis FBgn0021825
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0021825
GO:0008090
IEA
PLAZA Integrative Orthologyretrograde axonal transport FBgn0021825
GO:0030952
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cytoskeleton polarity FBgn0021825
GO:0030951
IEA
PLAZA Integrative Orthologyestablishment or maintenance of microtubule cytoskeleton polarity FBgn0021825

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding3
GO:0030507
IDA
Genome Projectspectrin binding
GO:0030507
IDA
Gene Ontologyspectrin binding4
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 5 6 7 8 9 10 11 12 13 14 15
GO:0003774
IEA
Genome Projectmotor activity
GO:0019901
IPI
Gene Ontologyprotein kinase binding8

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome16
GO:0031982
IDA
Genome Projectvesicle
GO:0031982
IDA
Gene Ontologyvesicle17
GO:0030426
IEA
Genome Projectgrowth cone
GO:0030286
IEA
Genome Projectdynein complex
GO:0016020
IEA
Genome Projectmembrane
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005869
IDA
Genome Projectdynactin complex
GO:0005869
IDA
Gene Ontologydynactin complex2
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome2 18
GO:0005737
IBA
Genome Projectcytoplasm
GO:0000776
IDA
Genome Projectkinetochore
GO:0000776
IDA
Gene Ontologykinetochore2
GO:0120111
IEA
PLAZA Integrative Orthologyneuron projection cytoplasm FBgn0021825
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle FBgn0021825
GO:0032838
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection cytoplasm FBgn0021825
GO:1904115
IEA
PLAZA Integrative Orthologyaxon cytoplasm FBgn0021825
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion FBgn0021825
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery FBgn0021825
GO:0099568
IEA
PLAZA Integrative Orthologycytoplasmic region FBgn0021825
GO:0005938
IEA
PLAZA Integrative Orthologycell cortex FBgn0021825

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR028133Dynamitin

No MapMan annotations defined for this gene.
KeggID Description
K10424DCTN2; dynactin 2
No chloroplast target sequence found.