Gene: ENSG00000172175 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000172175
Transcript Identifier
ENST00000348428
Gene Type
Coding gene
Location
18 : 58671644-58747842 : positive

Family Information

Homologous gene family
HOM02SEM038835
(2 genes in 2 species)
specific family

Descriptions

gene_descr
MALT1 paracaspase

Identifiers

Type Value
pidENSP00000319279
HGNC6819
UniprotQ9UDY8
RefSeq_mRNANM_006785.3
EMBLAB026118
EMBLAF130356
EMBLAF316597
EMBLAL137399
EMBLBC030143

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051259
IDA
Genome Projectprotein complex oligomerization
GO:0051259
IDA
Gene Ontologyprotein complex oligomerization1
GO:0051168
IDA
Genome Projectnuclear export
GO:0051168
IDA
Gene Ontologynuclear export2
GO:0051092
IMP
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051092
IMP
Gene Ontologypositive regulation of NF-kappaB transcription factor activity3
GO:0050870
IC
Genome Projectpositive regulation of T cell activation
GO:0050856
IEA
Genome Projectregulation of T cell receptor signaling pathway
GO:0050852
IDA
TAS
Genome ProjectT cell receptor signaling pathway
GO:0050852
IDA
TAS
Gene OntologyT cell receptor signaling pathway1
GO:0045087
IEA
Genome Projectinnate immune response
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123
Gene Ontologypositive regulation of I-kappaB kinase/NF-kappaB signaling4
GO:0043066
NAS
Genome Projectnegative regulation of apoptotic process
GO:0043066
NAS
Gene Ontologynegative regulation of apoptotic process5 6
GO:0042981
IDA
Genome Projectregulation of apoptotic process
GO:0042981
IDA
Gene Ontologyregulation of apoptotic process7
GO:0042098
IEA
Genome ProjectT cell proliferation
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038095
TAS
Gene OntologyFc-epsilon receptor signaling pathway
GO:0032743
IMP
Genome Projectpositive regulation of interleukin-2 production
GO:0032743
IMP
Gene Ontologypositive regulation of interleukin-2 production1
GO:0031398
NAS
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
NAS
Gene Ontologypositive regulation of protein ubiquitination3
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0009620
IEA
Genome Projectresponse to fungus
GO:0007250
IMP
Genome Projectactivation of NF-kappaB-inducing kinase activity
GO:0007250
IMP
Gene Ontologyactivation of NF-kappaB-inducing kinase activity1
GO:0006952
NAS
Genome Projectdefense response
GO:0006952
NAS
Gene Ontologydefense response8
GO:0006508
IDA
Genome Projectproteolysis
GO:0006508
IDA
Gene Ontologyproteolysis3
GO:0002726
IMP
Genome Projectpositive regulation of T cell cytokine production
GO:0002726
IMP
Gene Ontologypositive regulation of T cell cytokine production1
GO:0002237
IEA
Genome Projectresponse to molecule of bacterial origin
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0002223
TAS
Gene Ontologystimulatory C-type lectin receptor signaling pathway
GO:0001923
IEA
Genome ProjectB-1 B cell differentiation
GO:2000321
ISS
Gene Ontologypositive regulation of T-helper 17 cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019209
IMP
Genome Projectkinase activator activity
GO:0019209
IMP
Gene Ontologykinase activator activity1
GO:0043621
IPI
Genome Projectprotein self-association
GO:0043621
IPI
Gene Ontologyprotein self-association1
GO:0008233
IDA
Genome Projectpeptidase activity
GO:0008233
IDA
Gene Ontologypeptidase activity3
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 9 10 11 12 13 14 15 16 17
GO:0004842
IDA
Genome Projectubiquitin-protein transferase activity
GO:0004842
IDA
Gene Ontologyubiquitin-protein transferase activity1 9
GO:0004197
NAS
Genome Projectcysteine-type endopeptidase activity
GO:0004197
NAS
Gene Ontologycysteine-type endopeptidase activity5
GO:0002020
IEA
Genome Projectprotease binding
GO:0042802
IPI
Gene Ontologyidentical protein binding18

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0032449
NAS
Genome ProjectCBM complex
GO:0032449
IDA
NAS
Gene OntologyCBM complex1 19
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm2
GO:0005730
IDA
Genome Projectnucleolus
GO:0005730
IDA
Gene Ontologynucleolus
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus2
GO:0001650
IDA
Genome Projectfibrillar center
GO:0001650
IDA
Gene Ontologyfibrillar center
GO:0032991
IDA
Gene Ontologyprotein-containing complex1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001309Peptidase C14, p20 domain
IPR003598Immunoglobulin subtype 2
IPR003599Immunoglobulin subtype
IPR007110Immunoglobulin-like domain
IPR011029Death-like domain superfamily
IPR013783Immunoglobulin-like fold
IPR029030Caspase-like domain superfamily
IPR033540Mucosa-associated lymphoid tissue lymphoma translocation protein 1

No MapMan annotations defined for this gene.
KeggID Description
K07369MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1
No chloroplast target sequence found.