Gene: ENSG00000172053 (Homo sapiens)

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Gene Identifier
ENSG00000172053
Transcript Identifier
ENST00000306125
Gene Type
Coding gene
Location
3 : 49096029-49104733 : negative

Family Information

Homologous gene family
HOM02SEM000189
(145 genes in 26 species)
specific family
Orthologous gene family
ORTHO02SEM001232
(43 genes in 26 species)
specific family

Descriptions

gene_descr
glutaminyl-tRNA synthetase

Identifiers

Type Value
pidENSP00000307567
HGNC9751
UniprotP47897
RefSeq_mRNANM_005051.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2001234
IDA
Genome Projectnegative regulation of apoptotic signaling pathway
GO:2001234
IDA
Gene Ontologynegative regulation of apoptotic signaling pathway1
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045892
IDA
Gene Ontologynegative regulation of transcription, DNA-templated1
GO:0032873
IDA
Genome Projectnegative regulation of stress-activated MAPK cascade
GO:0032873
IDA
Gene Ontologynegative regulation of stress-activated MAPK cascade1
GO:0007420
IMP
Genome Projectbrain development
GO:0007420
IMP
Gene Ontologybrain development2
GO:0006469
IDA
Genome Projectnegative regulation of protein kinase activity
GO:0006469
IDA
Gene Ontologynegative regulation of protein kinase activity1
GO:0006425
IDA
Genome Projectglutaminyl-tRNA aminoacylation
GO:0006425
IDA
Gene Ontologyglutaminyl-tRNA aminoacylation2 3
GO:0006418
TAS
Genome ProjecttRNA aminoacylation for protein translation
GO:0006418
TAS
Gene OntologytRNA aminoacylation for protein translation
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0027090
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0027090
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT1G25350
GO:0048827
IEA
PLAZA Integrative Orthologyphyllome development AT1G25350
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0027090
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0027090
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0027090
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT1G25350
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0027090
GO:0090567
IEA
PLAZA Integrative Orthologyreproductive shoot system development AT1G25350
GO:0016358
IEA
PLAZA Integrative Orthologydendrite development FBgn0027090
GO:0099402
IEA
PLAZA Integrative Orthologyplant organ development AT1G25350
GO:0048467
IEA
PLAZA Integrative Orthologygynoecium development AT1G25350
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0027090
GO:0048813
IEA
PLAZA Integrative Orthologydendrite morphogenesis FBgn0027090
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0027090
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0027090
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0027090
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0027090
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0027090
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis FBgn0027090
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization FBgn0027090
GO:0035670
IEA
PLAZA Integrative Orthologyplant-type ovary development AT1G25350
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0027090
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0027090
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0027090
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT1G25350
GO:0048481
IEA
PLAZA Integrative Orthologyplant ovule development AT1G25350
GO:0048367
IEA
PLAZA Integrative Orthologyshoot system development AT1G25350
GO:0009908
IEA
PLAZA Integrative Orthologyflower development AT1G25350
GO:0048440
IEA
PLAZA Integrative Orthologycarpel development AT1G25350
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT1G25350
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT1G25350
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0027090
GO:0048437
IEA
PLAZA Integrative Orthologyfloral organ development AT1G25350
GO:0048438
IEA
PLAZA Integrative Orthologyfloral whorl development AT1G25350
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0027090
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT1G25350
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0027090
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0027090

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0019901
IPI
Gene Ontologyprotein kinase binding1
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 4 5 6 7
GO:0004860
IMP
Genome Projectprotein kinase inhibitor activity
GO:0004860
IMP
Gene Ontologyprotein kinase inhibitor activity1
GO:0004819
TAS
Genome Projectglutamine-tRNA ligase activity
GO:0004819
IDA
TAS
Gene Ontologyglutamine-tRNA ligase activity3
GO:0003676
IEA
PLAZA Integrative Orthologynucleic acid binding YOR168W
GO:0003729
IEA
PLAZA Integrative OrthologymRNA binding YOR168W
GO:0003723
IEA
PLAZA Integrative OrthologyRNA binding YOR168W

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0017101
IEA
Genome Projectaminoacyl-tRNA synthetase multienzyme complex
GO:0017101
IDA
Gene Ontologyaminoacyl-tRNA synthetase multienzyme complex8
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol9
GO:0005759
TAS
Genome Projectmitochondrial matrix
GO:0005759
TAS
Gene Ontologymitochondrial matrix
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm2 10
GO:0032991
IMP
Gene Ontologyprotein-containing complex1
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part FBgn0027090
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton FBgn0027090
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle FBgn0027090
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle FBgn0027090
GO:0005875
IEA
PLAZA Integrative Orthologymicrotubule associated complex FBgn0027090
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton FBgn0027090

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000924Glutamyl/glutaminyl-tRNA synthetase
IPR001412Aminoacyl-tRNA synthetase, class I, conserved site
IPR004514Glutamine-tRNA synthetase
IPR007638Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2
IPR007639Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal
IPR011035Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily
IPR014729Rossmann-like alpha/beta/alpha sandwich fold
IPR020056Ribosomal protein L25/Gln-tRNA synthetase, N-terminal
IPR020058Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
IPR020059Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
IPR020061Glutamine-tRNA ligase, alpha-bundle domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K01886QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
No chloroplast target sequence found.