Gene: ENSG00000170734 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000170734
Transcript Identifier
ENST00000372236
Gene Type
Coding gene
Location
6 : 43582320-43614557 : positive

Family Information

Homologous gene family
HOM02SEM001254
(43 genes in 26 species)
specific family

Descriptions

gene_descr
polymerase (DNA directed), eta

Identifiers

Type Value
pidENSP00000361310
HGNC9181
UniprotQ9Y253
UniprotA0A024RD62
RefSeq_mRNANM_006502.2
EMBLCH471081

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071494
IEA
Genome Projectcellular response to UV-C
GO:0070987
TAS
Genome Projecterror-free translesion synthesis
GO:0070987
TAS
Gene Ontologyerror-free translesion synthesis
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0019985
TAS
Gene Ontologytranslesion synthesis
GO:0010225
IDA
Genome Projectresponse to UV-C
GO:0010225
IDA
Gene Ontologyresponse to UV-C1
GO:0006290
IEA
Genome Projectpyrimidine dimer repair
GO:0006282
TAS
Genome Projectregulation of DNA repair
GO:0006282
TAS
Gene Ontologyregulation of DNA repair2
GO:0006281
TAS
Genome ProjectDNA repair
GO:0006281
TAS
Gene OntologyDNA repair3
GO:0006260
IEA
Genome ProjectDNA replication
GO:0000731
IDA
Genome ProjectDNA synthesis involved in DNA repair
GO:0000731
IDA
Gene OntologyDNA synthesis involved in DNA repair1
GO:0018205
IEA
PLAZA Integrative Orthologypeptidyl-lysine modification SPBC16A3.11
GO:0010564
IEA
PLAZA Integrative Orthologyregulation of cell cycle process SPBC16A3.11
GO:1901977
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle checkpoint WBGene00018721
GO:0045876
IEA
PLAZA Integrative Orthologypositive regulation of sister chromatid cohesion SPBC16A3.11
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPBC16A3.11
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction SPBC16A3.11
GO:1901976
IEA
PLAZA Integrative Orthologyregulation of cell cycle checkpoint WBGene00018721
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPBC16A3.11
GO:0006473
IEA
PLAZA Integrative Orthologyprotein acetylation SPBC16A3.11
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process SPBC16A3.11
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process SPBC16A3.11
GO:0006475
IEA
PLAZA Integrative Orthologyinternal protein amino acid acetylation SPBC16A3.11
GO:0034087
IEA
PLAZA Integrative Orthologyestablishment of mitotic sister chromatid cohesion SPBC16A3.11
GO:1904289
IEA
PLAZA Integrative Orthologyregulation of mitotic DNA damage checkpoint WBGene00018721
GO:0034088
IEA
PLAZA Integrative Orthologymaintenance of mitotic sister chromatid cohesion SPBC16A3.11
GO:0034089
IEA
PLAZA Integrative Orthologyestablishment of meiotic sister chromatid cohesion SPBC16A3.11
GO:0034085
IEA
PLAZA Integrative Orthologyestablishment of sister chromatid cohesion SPBC16A3.11
GO:0034086
IEA
PLAZA Integrative Orthologymaintenance of sister chromatid cohesion SPBC16A3.11
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process WBGene00018721
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process WBGene00018721
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus WBGene00018721
GO:0051984
IEA
PLAZA Integrative Orthologypositive regulation of chromosome segregation SPBC16A3.11
GO:0051983
IEA
PLAZA Integrative Orthologyregulation of chromosome segregation SPBC16A3.11
GO:0034091
IEA
PLAZA Integrative Orthologyregulation of maintenance of sister chromatid cohesion SPBC16A3.11
GO:0034093
IEA
PLAZA Integrative Orthologypositive regulation of maintenance of sister chromatid cohesion SPBC16A3.11
GO:0044774
IEA
PLAZA Integrative Orthologymitotic DNA integrity checkpoint WBGene00018721
GO:1901564
IEA
PLAZA Integrative Orthologyorganonitrogen compound metabolic process SPBC16A3.11
GO:0044773
IEA
PLAZA Integrative Orthologymitotic DNA damage checkpoint WBGene00018721
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development WBGene00018721
GO:0006464
IEA
PLAZA Integrative Orthologycellular protein modification process SPBC16A3.11
GO:0033043
IEA
PLAZA Integrative Orthologyregulation of organelle organization SPBC16A3.11
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development WBGene00018721
GO:0033044
IEA
PLAZA Integrative Orthologyregulation of chromosome organization SPBC16A3.11
GO:0033045
IEA
PLAZA Integrative Orthologyregulation of sister chromatid segregation SPBC16A3.11
GO:0019538
IEA
PLAZA Integrative Orthologyprotein metabolic process SPBC16A3.11
GO:0010224
IEA
PLAZA Integrative Orthologyresponse to UV-B AT5G44740
GO:0071962
IEA
PLAZA Integrative Orthologymitotic sister chromatid cohesion, centromeric SPBC16A3.11
GO:0033047
IEA
PLAZA Integrative Orthologyregulation of mitotic sister chromatid segregation SPBC16A3.11
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPBC16A3.11
GO:2000720
IEA
PLAZA Integrative Orthologypositive regulation of maintenance of mitotic sister chromatid cohesion, centromeric SPBC16A3.11
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPBC16A3.11
GO:0071960
IEA
PLAZA Integrative Orthologymaintenance of mitotic sister chromatid cohesion, centromeric SPBC16A3.11
GO:0051177
IEA
PLAZA Integrative Orthologymeiotic sister chromatid cohesion SPBC16A3.11
GO:0007346
IEA
PLAZA Integrative Orthologyregulation of mitotic cell cycle SPBC16A3.11
GO:0007064
IEA
PLAZA Integrative Orthologymitotic sister chromatid cohesion SPBC16A3.11
GO:0007063
IEA
PLAZA Integrative Orthologyregulation of sister chromatid cohesion SPBC16A3.11
GO:2001021
IEA
PLAZA Integrative Orthologynegative regulation of response to DNA damage stimulus WBGene00018721
GO:0007062
IEA
PLAZA Integrative Orthologysister chromatid cohesion SPBC16A3.11
GO:0051726
IEA
PLAZA Integrative Orthologyregulation of cell cycle SPBC16A3.11
GO:0098813
IEA
PLAZA Integrative Orthologynuclear chromosome segregation SPBC16A3.11
GO:0018193
IEA
PLAZA Integrative Orthologypeptidyl-amino acid modification SPBC16A3.11
GO:2000718
IEA
PLAZA Integrative Orthologyregulation of maintenance of mitotic sister chromatid cohesion, centromeric SPBC16A3.11
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle SPBC16A3.11
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission SPBC16A3.11
GO:0045840
IEA
PLAZA Integrative Orthologypositive regulation of mitotic nuclear division SPBC16A3.11
GO:0043543
IEA
PLAZA Integrative Orthologyprotein acylation SPBC16A3.11
GO:0007059
IEA
PLAZA Integrative Orthologychromosome segregation SPBC16A3.11
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process SPBC16A3.11
GO:1903047
IEA
PLAZA Integrative Orthologymitotic cell cycle process SPBC16A3.11
GO:2001252
IEA
PLAZA Integrative Orthologypositive regulation of chromosome organization SPBC16A3.11
GO:0036211
IEA
PLAZA Integrative Orthologyprotein modification process SPBC16A3.11
GO:0000819
IEA
PLAZA Integrative Orthologysister chromatid segregation SPBC16A3.11
GO:0018003
IEA
PLAZA Integrative Orthologypeptidyl-lysine N6-acetylation SPBC16A3.11
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization SPBC16A3.11
GO:0043412
IEA
PLAZA Integrative Orthologymacromolecule modification SPBC16A3.11
GO:0006310
IEA
PLAZA Integrative OrthologyDNA recombination FBgn0037141
GO:0000724
IEA
PLAZA Integrative Orthologydouble-strand break repair via homologous recombination FBgn0037141
GO:0000725
IEA
PLAZA Integrative Orthologyrecombinational repair FBgn0037141
GO:0062033
IEA
PLAZA Integrative Orthologypositive regulation of mitotic sister chromatid segregation SPBC16A3.11
GO:0007088
IEA
PLAZA Integrative Orthologyregulation of mitotic nuclear division SPBC16A3.11
GO:0031570
IEA
PLAZA Integrative OrthologyDNA integrity checkpoint WBGene00018721
GO:0061983
IEA
PLAZA Integrative Orthologymeiosis II cell cycle process SPBC16A3.11
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division SPBC16A3.11
GO:0140014
IEA
PLAZA Integrative Orthologymitotic nuclear division SPBC16A3.11
GO:0010638
IEA
PLAZA Integrative Orthologypositive regulation of organelle organization SPBC16A3.11
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division SPBC16A3.11
GO:0051783
IEA
PLAZA Integrative Orthologyregulation of nuclear division SPBC16A3.11
GO:0051785
IEA
PLAZA Integrative Orthologypositive regulation of nuclear division SPBC16A3.11
GO:0006302
IEA
PLAZA Integrative Orthologydouble-strand break repair FBgn0037141
GO:0000278
IEA
PLAZA Integrative Orthologymitotic cell cycle SPBC16A3.11
GO:0070192
IEA
PLAZA Integrative Orthologychromosome organization involved in meiotic cell cycle SPBC16A3.11
GO:0045787
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle SPBC16A3.11
GO:0042276
IEA
PLAZA Integrative Orthologyerror-prone translesion synthesis SPBC16A3.11
GO:0045786
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle WBGene00018721
GO:0009650
IEA
PLAZA Integrative OrthologyUV protection AT5G44740
GO:2000001
IEA
PLAZA Integrative Orthologyregulation of DNA damage checkpoint WBGene00018721
GO:2000002
IEA
PLAZA Integrative Orthologynegative regulation of DNA damage checkpoint WBGene00018721
GO:0000070
IEA
PLAZA Integrative Orthologymitotic sister chromatid segregation SPBC16A3.11
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization SPBC16A3.11
GO:0045144
IEA
PLAZA Integrative Orthologymeiotic sister chromatid segregation SPBC16A3.11
GO:0000075
IEA
PLAZA Integrative Orthologycell cycle checkpoint WBGene00018721
GO:0010948
IEA
PLAZA Integrative Orthologynegative regulation of cell cycle process WBGene00018721
GO:0000077
IEA
PLAZA Integrative OrthologyDNA damage checkpoint WBGene00018721
GO:0045931
IEA
PLAZA Integrative Orthologypositive regulation of mitotic cell cycle SPBC16A3.11
GO:0048523
IEA
PLAZA Integrative Orthologynegative regulation of cellular process WBGene00018721
GO:0045930
IEA
PLAZA Integrative Orthologynegative regulation of mitotic cell cycle WBGene00018721
GO:0090068
IEA
PLAZA Integrative Orthologypositive regulation of cell cycle process SPBC16A3.11
GO:0034182
IEA
PLAZA Integrative Orthologyregulation of maintenance of mitotic sister chromatid cohesion SPBC16A3.11
GO:0034184
IEA
PLAZA Integrative Orthologypositive regulation of maintenance of mitotic sister chromatid cohesion SPBC16A3.11
GO:0070602
IEA
PLAZA Integrative Orthologyregulation of centromeric sister chromatid cohesion SPBC16A3.11
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization SPBC16A3.11
GO:0070601
IEA
PLAZA Integrative Orthologycentromeric sister chromatid cohesion SPBC16A3.11
GO:1904290
IEA
PLAZA Integrative Orthologynegative regulation of mitotic DNA damage checkpoint WBGene00018721
GO:0045132
IEA
PLAZA Integrative Orthologymeiotic chromosome segregation SPBC16A3.11
GO:0018393
IEA
PLAZA Integrative Orthologyinternal peptidyl-lysine acetylation SPBC16A3.11
GO:0018394
IEA
PLAZA Integrative Orthologypeptidyl-lysine acetylation SPBC16A3.11
GO:0048522
IEA
PLAZA Integrative Orthologypositive regulation of cellular process SPBC16A3.11
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process SPBC16A3.11
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process WBGene00018721
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPBC16A3.11
GO:0007135
IEA
PLAZA Integrative Orthologymeiosis II SPBC16A3.11
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching WBGene00018721
GO:0007093
IEA
PLAZA Integrative Orthologymitotic cell cycle checkpoint WBGene00018721
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development WBGene00018721

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding4 5 6
GO:0003887
TAS
Genome ProjectDNA-directed DNA polymerase activity
GO:0003887
TAS
Gene OntologyDNA-directed DNA polymerase activity
GO:0003684
IEA
Genome Projectdamaged DNA binding
GO:0008080
IEA
PLAZA Integrative OrthologyN-acetyltransferase activity SPBC16A3.11
GO:0016747
IEA
PLAZA Integrative Orthologytransferase activity, transferring acyl groups other than amino-acyl groups SPBC16A3.11
GO:0016746
IEA
PLAZA Integrative Orthologytransferase activity, transferring acyl groups SPBC16A3.11
GO:0016410
IEA
PLAZA Integrative OrthologyN-acyltransferase activity SPBC16A3.11
GO:0052858
IEA
PLAZA Integrative Orthologypeptidyl-lysine acetyltransferase activity SPBC16A3.11
GO:0016407
IEA
PLAZA Integrative Orthologyacetyltransferase activity SPBC16A3.11

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IDA
Genome Projectcytosol
GO:0005829
IDA
Gene Ontologycytosol
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005657
IEA
PLAZA Integrative Orthologyreplication fork SPBC16A3.11
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPBC16A3.11
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPBC16A3.11
GO:0000790
IEA
PLAZA Integrative Orthologynuclear chromatin SPBC16A3.11
GO:0000785
IEA
PLAZA Integrative Orthologychromatin SPBC16A3.11
GO:0005739
IEA
PLAZA Integrative Orthologymitochondrion YDR419W
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPBC16A3.11
GO:0044454
IEA
PLAZA Integrative Orthologynuclear chromosome part SPBC16A3.11
GO:0000228
IEA
PLAZA Integrative Orthologynuclear chromosome SPBC16A3.11
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPBC16A3.11
GO:0043596
IEA
PLAZA Integrative Orthologynuclear replication fork SPBC16A3.11
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPBC16A3.11
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPBC16A3.11

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001126UmuC domain
IPR017961DNA polymerase, Y-family, little finger domain

No MapMan annotations defined for this gene.
KeggID Description
K03509POLH; DNA polymerase eta [EC:2.7.7.7]
No chloroplast target sequence found.