Gene: ENSG00000169372 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000169372
Transcript Identifier
ENST00000542893
Gene Type
Coding gene
Location
12 : 93678775-93850271 : positive

Family Information

Homologous gene family
HOM02SEM071778
(orphan gene)
specific family

Descriptions

gene_descr
CASP2 and RIPK1 domain containing adaptor with death domain

Identifiers

Type Value
pidENSP00000439068
HGNC2340
UniprotP78560
UniprotQ53XL1
EMBLAK314861
EMBLBT009837
EMBLCH471054
EMBLCR407643

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2001235
IEA
Genome Projectpositive regulation of apoptotic signaling pathway
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus
GO:0071260
IEP
Gene Ontologycellular response to mechanical stimulus1
GO:0042981
TAS
Genome Projectregulation of apoptotic process
GO:0042981
TAS
Gene Ontologyregulation of apoptotic process
GO:0008625
IC
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0008625
IC
Gene Ontologyextrinsic apoptotic signaling pathway via death domain receptors2
GO:0006977
IMP
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0006977
IMP
Gene OntologyDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest3
GO:0006919
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043065
IDA
Gene Ontologypositive regulation of apoptotic process4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070513
IPI
Genome Projectdeath domain binding
GO:0070513
IPI
Gene Ontologydeath domain binding2
GO:0030674
IPI
Genome Projectprotein binding, bridging
GO:0030674
IPI
Gene Ontologyprotein binding, bridging2
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding5 6 7 8 9 10 11 12
GO:0002020
IPI
Genome Projectprotease binding
GO:0002020
IPI
Gene Ontologyprotease binding2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005737
ISS
Genome Projectcytoplasm
GO:0005737
ISS
Gene Ontologycytoplasm
GO:0005634
ISS
Genome Projectnucleus
GO:0005634
ISS
Gene Ontologynucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000488Death domain
IPR001315CARD domain
IPR011029Death-like domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K02832RAIDD; CASP2 and RIPK1 domain containing adaptor with death domain
No chloroplast target sequence found.