Gene: ENSG00000166233 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000166233
Transcript Identifier
ENST00000379887
Gene Type
Coding gene
Location
15 : 72474640-72583292 : positive

Family Information

Homologous gene family
HOM02SEM000183
(147 genes in 24 species)
specific family

Descriptions

gene_descr
ariadne RBR E3 ubiquitin protein ligase 1

Identifiers

Type Value
pidENSP00000369217
HGNC689
UniprotQ9Y4X5
RefSeq_mRNANM_005744.3
EMBLAB014774
EMBLAC079322
EMBLAC100827
EMBLAF072832
EMBLAJ009771
EMBLAJ130976
EMBLAJ243190
EMBLAK312715
EMBLBC051877
EMBLCH471082

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032436
IBA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567
IDA
Genome Projectprotein ubiquitination
GO:0016567
IDA
Gene Ontologyprotein ubiquitination1 2 3 4 5 6
GO:0006511
TAS
Genome Projectubiquitin-dependent protein catabolic process
GO:0006511
TAS
Gene Ontologyubiquitin-dependent protein catabolic process7
GO:0000209
IBA
Genome Projectprotein polyubiquitination
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development FBgn0017418
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process FBgn0017418
GO:0010720
IEA
PLAZA Integrative Orthologypositive regulation of cell development FBgn0017418
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0017418
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus AT1G05880
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0017418
GO:0051276
IEA
PLAZA Integrative Orthologychromosome organization YKR017C
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0017418
GO:0007127
IEA
PLAZA Integrative Orthologymeiosis I SPAC328.02
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0017418
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress AT1G05880
GO:0007049
IEA
PLAZA Integrative Orthologycell cycle SPAC328.02
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction SPAC328.02
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization SPAC328.02
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0017418
GO:0045597
IEA
PLAZA Integrative Orthologypositive regulation of cell differentiation FBgn0017418
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process SPAC328.02
GO:0061982
IEA
PLAZA Integrative Orthologymeiosis I cell cycle process SPAC328.02
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process AT5G63730
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0017418
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0017418
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division SPAC328.02
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus AT1G05880
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0017418
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process AT5G63730
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress AT1G05880
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division SPAC328.02
GO:0045595
IEA
PLAZA Integrative Orthologyregulation of cell differentiation FBgn0017418
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0017418
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus AT1G05880
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0017418
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0017418
GO:0009411
IEA
PLAZA Integrative Orthologyresponse to UV AT1G05880
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0017418
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0017418
GO:0080155
IEA
PLAZA Integrative Orthologyregulation of double fertilization forming a zygote and endosperm AT5G63730
GO:0080154
IEA
PLAZA Integrative Orthologyregulation of fertilization AT5G63730
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0017418
GO:0010224
IEA
PLAZA Integrative Orthologyresponse to UV-B AT1G05880
GO:0050767
IEA
PLAZA Integrative Orthologyregulation of neurogenesis FBgn0017418
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction AT5G63730
GO:0050769
IEA
PLAZA Integrative Orthologypositive regulation of neurogenesis FBgn0017418
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis SPAC328.02
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization SPAC328.02
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0017418
GO:0007029
IEA
PLAZA Integrative Orthologyendoplasmic reticulum organization FBgn0017418
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical AT1G05880
GO:0009566
IEA
PLAZA Integrative Orthologyfertilization AT5G63730
GO:0009567
IEA
PLAZA Integrative Orthologydouble fertilization forming a zygote and endosperm AT5G63730
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0017418
GO:0010256
IEA
PLAZA Integrative Orthologyendomembrane system organization FBgn0017418
GO:0036205
IEA
PLAZA Integrative Orthologyhistone catabolic process YKR017C
GO:0070887
IEA
PLAZA Integrative Orthologycellular response to chemical stimulus AT1G05880
GO:0016574
IEA
PLAZA Integrative Orthologyhistone ubiquitination YKR017C
GO:0071456
IEA
PLAZA Integrative Orthologycellular response to hypoxia AT1G05880
GO:0016570
IEA
PLAZA Integrative Orthologyhistone modification YKR017C
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process FBgn0017418
GO:0071453
IEA
PLAZA Integrative Orthologycellular response to oxygen levels AT1G05880
GO:0051960
IEA
PLAZA Integrative Orthologyregulation of nervous system development FBgn0017418
GO:0001666
IEA
PLAZA Integrative Orthologyresponse to hypoxia AT1G05880
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process FBgn0017418
GO:0009628
IEA
PLAZA Integrative Orthologyresponse to abiotic stimulus AT1G05880
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle SPAC328.02
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission SPAC328.02
GO:0051962
IEA
PLAZA Integrative Orthologypositive regulation of nervous system development FBgn0017418
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0017418
GO:0070482
IEA
PLAZA Integrative Orthologyresponse to oxygen levels AT1G05880
GO:0006325
IEA
PLAZA Integrative Orthologychromatin organization YKR017C
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process FBgn0017418
GO:0036293
IEA
PLAZA Integrative Orthologyresponse to decreased oxygen levels AT1G05880
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0017418
GO:0009314
IEA
PLAZA Integrative Orthologyresponse to radiation AT1G05880
GO:0022402
IEA
PLAZA Integrative Orthologycell cycle process SPAC328.02
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process SPAC328.02
GO:0060284
IEA
PLAZA Integrative Orthologyregulation of cell development FBgn0017418
GO:0036294
IEA
PLAZA Integrative Orthologycellular response to decreased oxygen levels AT1G05880
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process AT5G63730
GO:0016569
IEA
PLAZA Integrative Orthologycovalent chromatin modification YKR017C
GO:0043900
IEA
PLAZA Integrative Orthologyregulation of multi-organism process AT5G63730
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0017418

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061630
IBA
Genome Projectubiquitin protein ligase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0031625
IPI
Gene Ontologyubiquitin protein ligase binding3 8
GO:0031624
IPI
Genome Projectubiquitin conjugating enzyme binding
GO:0031624
IPI
Gene Ontologyubiquitin conjugating enzyme binding4 5 6
GO:0019787
TAS
Genome Projectubiquitin-like protein transferase activity
GO:0019787
TAS
Gene Ontologyubiquitin-like protein transferase activity7
GO:0008270
IDA
Genome Projectzinc ion binding
GO:0008270
IDA
Gene Ontologyzinc ion binding2 4
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 4 5 7
GO:0004842
IDA
TAS
Genome Projectubiquitin-protein transferase activity
GO:0004842
IDA
TAS
Gene Ontologyubiquitin-protein transferase activity1 2 3 4 5 6
GO:0046983
IEA
PLAZA Integrative Orthologyprotein dimerization activity FBgn0017418

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031464
IDA
Genome ProjectCul4A-RING E3 ubiquitin ligase complex
GO:0031464
IDA
Gene OntologyCul4A-RING E3 ubiquitin ligase complex5
GO:0031463
IDA
Genome ProjectCul3-RING ubiquitin ligase complex
GO:0031463
IDA
Gene OntologyCul3-RING ubiquitin ligase complex5 6
GO:0031462
IDA
Genome ProjectCul2-RING ubiquitin ligase complex
GO:0031462
IDA
Gene OntologyCul2-RING ubiquitin ligase complex5 6
GO:0019005
IDA
Genome ProjectSCF ubiquitin ligase complex
GO:0019005
IDA
Gene OntologySCF ubiquitin ligase complex5 6
GO:0097413
IDA
Genome ProjectLewy body
GO:0097413
IDA
Gene OntologyLewy body9
GO:0016604
IDA
Genome Projectnuclear body
GO:0016604
IDA
Gene Ontologynuclear body10
GO:0015030
IEA
Genome ProjectCajal body
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm8 10
GO:0000151
TAS
Genome Projectubiquitin ligase complex
GO:0000151
TAS
Gene Ontologyubiquitin ligase complex7
GO:0044427
IEA
PLAZA Integrative Orthologychromosomal part SPAC328.02
GO:0005694
IEA
PLAZA Integrative Orthologychromosome SPAC328.02
GO:0035861
IEA
PLAZA Integrative Orthologysite of double-strand break SPAC328.02
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle SPAC328.02
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle SPAC328.02
GO:0090734
IEA
PLAZA Integrative Orthologysite of DNA damage SPAC328.02

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001841Zinc finger, RING-type
IPR002867IBR domain
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR031127E3 ubiquitin ligase RBR family

No MapMan annotations defined for this gene.
KeggID Description
K11968ARIH1; ariadne-1 [EC:2.3.2.31]
No chloroplast target sequence found.