Gene: ENSG00000164056 (Homo sapiens)

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Gene Identifier
ENSG00000164056
Transcript Identifier
ENST00000394339
Gene Type
Coding gene
Location
4 : 123401592-123402551 : positive

Family Information

Homologous gene family
HOM02SEM016119
(5 genes in 2 species)
specific family
Orthologous gene family
ORTHO02SEM012342
(5 genes in 2 species)
specific family

Descriptions

gene_descr
sprouty homolog 1, antagonist of FGF signaling (Drosophila)

Identifiers

Type Value
pidENSP00000377871
HGNC11269
UniprotO43609
RefSeq_mRNANM_005841.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070373
ISS
Genome Projectnegative regulation of ERK1 and ERK2 cascade
GO:0070373
ISS
Gene Ontologynegative regulation of ERK1 and ERK2 cascade
GO:0060940
ISS
Genome Projectepithelial to mesenchymal transition involved in cardiac fibroblast development
GO:0060940
ISS
Gene Ontologyepithelial to mesenchymal transition involved in cardiac fibroblast development
GO:0060449
IEA
Genome Projectbud elongation involved in lung branching
GO:0051387
IEA
Genome Projectnegative regulation of neurotrophin TRK receptor signaling pathway
GO:0046580
IEA
Genome Projectnegative regulation of Ras protein signal transduction
GO:0043407
IEA
Genome Projectnegative regulation of MAP kinase activity
GO:0042059
TAS
Genome Projectnegative regulation of epidermal growth factor receptor signaling pathway
GO:0042059
TAS
Gene Ontologynegative regulation of epidermal growth factor receptor signaling pathway
GO:0040037
IEA
Genome Projectnegative regulation of fibroblast growth factor receptor signaling pathway
GO:0034260
IEA
Genome Projectnegative regulation of GTPase activity
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0001759
IEA
Genome Projectorgan induction
GO:0001657
IEA
Genome Projectureteric bud development
GO:0001656
IEA
Genome Projectmetanephros development
GO:0000132
IEA
Genome Projectestablishment of mitotic spindle orientation
GO:0120175
IEA
PLAZA Integrative Orthologyregulation of torso signaling pathway FBgn0014388
GO:0001738
IEA
PLAZA Integrative Orthologymorphogenesis of a polarized epithelium FBgn0014388
GO:0001736
IEA
PLAZA Integrative Orthologyestablishment of planar polarity FBgn0014388
GO:0048477
IEA
PLAZA Integrative Orthologyoogenesis FBgn0014388
GO:0048592
IEA
PLAZA Integrative Orthologyeye morphogenesis FBgn0014388
GO:0048747
IEA
PLAZA Integrative Orthologymuscle fiber development FBgn0014388
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism FBgn0014388
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction FBgn0014388
GO:0048749
IEA
PLAZA Integrative Orthologycompound eye development FBgn0014388
GO:0035171
IEA
PLAZA Integrative Orthologylamellocyte differentiation FBgn0014388
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0014388
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process FBgn0014388
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0014388
GO:0007164
IEA
PLAZA Integrative Orthologyestablishment of tissue polarity FBgn0014388
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process FBgn0014388
GO:0007281
IEA
PLAZA Integrative Orthologygerm cell development FBgn0014388
GO:0048580
IEA
PLAZA Integrative Orthologyregulation of post-embryonic development FBgn0014388
GO:0045596
IEA
PLAZA Integrative Orthologynegative regulation of cell differentiation FBgn0014388
GO:0045595
IEA
PLAZA Integrative Orthologyregulation of cell differentiation FBgn0014388
GO:0048581
IEA
PLAZA Integrative Orthologynegative regulation of post-embryonic development FBgn0014388
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction FBgn0014388
GO:0007429
IEA
PLAZA Integrative Orthologysecondary branching, open tracheal system FBgn0014388
GO:0048736
IEA
PLAZA Integrative Orthologyappendage development FBgn0014388
GO:0048737
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage development FBgn0014388
GO:0042478
IEA
PLAZA Integrative Orthologyregulation of eye photoreceptor cell development FBgn0014388
GO:0048732
IEA
PLAZA Integrative Orthologygland development FBgn0014388
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0014388
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0014388
GO:0007430
IEA
PLAZA Integrative Orthologyterminal branching, open tracheal system FBgn0014388
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation FBgn0014388
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0014388
GO:0090596
IEA
PLAZA Integrative Orthologysensory organ morphogenesis FBgn0014388
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0014388
GO:0120177
IEA
PLAZA Integrative Orthologynegative regulation of torso signaling pathway FBgn0014388
GO:0050767
IEA
PLAZA Integrative Orthologyregulation of neurogenesis FBgn0014388
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction FBgn0014388
GO:0035107
IEA
PLAZA Integrative Orthologyappendage morphogenesis FBgn0014388
GO:0110116
IEA
PLAZA Integrative Orthologyregulation of compound eye photoreceptor cell differentiation FBgn0014388
GO:0001754
IEA
PLAZA Integrative Orthologyeye photoreceptor cell differentiation FBgn0014388
GO:0001751
IEA
PLAZA Integrative Orthologycompound eye photoreceptor cell differentiation FBgn0014388
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation FBgn0014388
GO:0042067
IEA
PLAZA Integrative Orthologyestablishment of ommatidial planar polarity FBgn0014388
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0014388
GO:0009886
IEA
PLAZA Integrative Orthologypost-embryonic animal morphogenesis FBgn0014388
GO:0042462
IEA
PLAZA Integrative Orthologyeye photoreceptor cell development FBgn0014388
GO:0009880
IEA
PLAZA Integrative Orthologyembryonic pattern specification FBgn0014388
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0014388
GO:0016318
IEA
PLAZA Integrative Orthologyommatidial rotation FBgn0014388
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process FBgn0014388
GO:0010454
IEA
PLAZA Integrative Orthologynegative regulation of cell fate commitment FBgn0014388
GO:0016334
IEA
PLAZA Integrative Orthologyestablishment or maintenance of polarity of follicular epithelium FBgn0014388
GO:0035114
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage morphogenesis FBgn0014388
GO:0010453
IEA
PLAZA Integrative Orthologyregulation of cell fate commitment FBgn0014388
GO:0016333
IEA
PLAZA Integrative Orthologymorphogenesis of follicular epithelium FBgn0014388
GO:0110109
IEA
PLAZA Integrative Orthologynegative regulation of imaginal disc-derived wing vein specification FBgn0014388
GO:0055002
IEA
PLAZA Integrative Orthologystriated muscle cell development FBgn0014388
GO:0042461
IEA
PLAZA Integrative Orthologyphotoreceptor cell development FBgn0014388
GO:0048563
IEA
PLAZA Integrative Orthologypost-embryonic animal organ morphogenesis FBgn0014388
GO:0042063
IEA
PLAZA Integrative Orthologygliogenesis FBgn0014388
GO:0001745
IEA
PLAZA Integrative Orthologycompound eye morphogenesis FBgn0014388
GO:0110107
IEA
PLAZA Integrative Orthologyregulation of imaginal disc-derived wing vein specification FBgn0014388
GO:0051960
IEA
PLAZA Integrative Orthologyregulation of nervous system development FBgn0014388
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction FBgn0014388
GO:0060446
IEA
PLAZA Integrative Orthologybranching involved in open tracheal system development FBgn0014388
GO:0110111
IEA
PLAZA Integrative Orthologynegative regulation of animal organ morphogenesis FBgn0014388
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0014388
GO:0002164
IEA
PLAZA Integrative Orthologylarval development FBgn0014388
GO:0046532
IEA
PLAZA Integrative Orthologyregulation of photoreceptor cell differentiation FBgn0014388
GO:0009996
IEA
PLAZA Integrative Orthologynegative regulation of cell fate specification FBgn0014388
GO:0035120
IEA
PLAZA Integrative Orthologypost-embryonic appendage morphogenesis FBgn0014388
GO:0060284
IEA
PLAZA Integrative Orthologyregulation of cell development FBgn0014388
GO:0007292
IEA
PLAZA Integrative Orthologyfemale gamete generation FBgn0014388
GO:0010001
IEA
PLAZA Integrative Orthologyglial cell differentiation FBgn0014388
GO:0042692
IEA
PLAZA Integrative Orthologymuscle cell differentiation FBgn0014388
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment FBgn0014388
GO:0046530
IEA
PLAZA Integrative Orthologyphotoreceptor cell differentiation FBgn0014388
GO:0042051
IEA
PLAZA Integrative Orthologycompound eye photoreceptor development FBgn0014388
GO:0001654
IEA
PLAZA Integrative Orthologyeye development FBgn0014388
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0014388
GO:0045314
IEA
PLAZA Integrative Orthologyregulation of compound eye photoreceptor development FBgn0014388
GO:0055001
IEA
PLAZA Integrative Orthologymuscle cell development FBgn0014388
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0014388
GO:1905330
IEA
PLAZA Integrative Orthologyregulation of morphogenesis of an epithelium FBgn0014388
GO:1905331
IEA
PLAZA Integrative Orthologynegative regulation of morphogenesis of an epithelium FBgn0014388
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0014388
GO:0048542
IEA
PLAZA Integrative Orthologylymph gland development FBgn0014388
GO:0051146
IEA
PLAZA Integrative Orthologystriated muscle cell differentiation FBgn0014388
GO:0002066
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell development FBgn0014388
GO:0048534
IEA
PLAZA Integrative Orthologyhematopoietic or lymphoid organ development FBgn0014388
GO:0002065
IEA
PLAZA Integrative Orthologycolumnar/cuboidal epithelial cell differentiation FBgn0014388
GO:0045664
IEA
PLAZA Integrative Orthologyregulation of neuron differentiation FBgn0014388
GO:0002064
IEA
PLAZA Integrative Orthologyepithelial cell development FBgn0014388
GO:0007474
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing vein specification FBgn0014388
GO:0007476
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing morphogenesis FBgn0014388
GO:0007350
IEA
PLAZA Integrative Orthologyblastoderm segmentation FBgn0014388
GO:0030097
IEA
PLAZA Integrative Orthologyhemopoiesis FBgn0014388
GO:0007351
IEA
PLAZA Integrative Orthologytripartite regional subdivision FBgn0014388
GO:0007472
IEA
PLAZA Integrative Orthologywing disc morphogenesis FBgn0014388
GO:0150063
IEA
PLAZA Integrative Orthologyvisual system development FBgn0014388
GO:0007424
IEA
PLAZA Integrative Orthologyopen tracheal system development FBgn0014388
GO:0007423
IEA
PLAZA Integrative Orthologysensory organ development FBgn0014388
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process FBgn0014388
GO:0007426
IEA
PLAZA Integrative Orthologytracheal outgrowth, open tracheal system FBgn0014388
GO:0021782
IEA
PLAZA Integrative Orthologyglial cell development FBgn0014388
GO:0042387
IEA
PLAZA Integrative Orthologyplasmatocyte differentiation FBgn0014388
GO:0042386
IEA
PLAZA Integrative Orthologyhemocyte differentiation FBgn0014388
GO:0035153
IEA
PLAZA Integrative Orthologyepithelial cell type specification, open tracheal system FBgn0014388
GO:0008595
IEA
PLAZA Integrative Orthologyanterior/posterior axis specification, embryo FBgn0014388
GO:0035155
IEA
PLAZA Integrative Orthologynegative regulation of terminal cell fate specification, open tracheal system FBgn0014388
GO:0035154
IEA
PLAZA Integrative Orthologyterminal cell fate specification, open tracheal system FBgn0014388
GO:0001708
IEA
PLAZA Integrative Orthologycell fate specification FBgn0014388
GO:0061061
IEA
PLAZA Integrative Orthologymuscle structure development FBgn0014388
GO:0051241
IEA
PLAZA Integrative Orthologynegative regulation of multicellular organismal process FBgn0014388
GO:0030707
IEA
PLAZA Integrative Orthologyovarian follicle cell development FBgn0014388
GO:0009948
IEA
PLAZA Integrative Orthologyanterior/posterior axis specification FBgn0014388
GO:0048880
IEA
PLAZA Integrative Orthologysensory system development FBgn0014388
GO:0002520
IEA
PLAZA Integrative Orthologyimmune system development FBgn0014388
GO:0009953
IEA
PLAZA Integrative Orthologydorsal/ventral pattern formation FBgn0014388
GO:0000578
IEA
PLAZA Integrative Orthologyembryonic axis specification FBgn0014388
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0014388
GO:0009950
IEA
PLAZA Integrative Orthologydorsal/ventral axis specification FBgn0014388
GO:0008069
IEA
PLAZA Integrative Orthologydorsal/ventral axis specification, ovarian follicular epithelium FBgn0014388
GO:0051093
IEA
PLAZA Integrative Orthologynegative regulation of developmental process FBgn0014388
GO:0009952
IEA
PLAZA Integrative Orthologyanterior/posterior pattern specification FBgn0014388
GO:0009798
IEA
PLAZA Integrative Orthologyaxis specification FBgn0014388
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development FBgn0014388
GO:0035282
IEA
PLAZA Integrative Orthologysegmentation FBgn0014388
GO:0035168
IEA
PLAZA Integrative Orthologylarval lymph gland hemocyte differentiation FBgn0014388
GO:0042659
IEA
PLAZA Integrative Orthologyregulation of cell fate specification FBgn0014388
GO:0035167
IEA
PLAZA Integrative Orthologylarval lymph gland hemopoiesis FBgn0014388
GO:0035166
IEA
PLAZA Integrative Orthologypost-embryonic hemopoiesis FBgn0014388
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0014388

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005886
TAS
Gene Ontologyplasma membrane
GO:0005829
IDA
ISS
TAS
Genome Projectcytosol
GO:0005829
IDA
ISS
TAS
Gene Ontologycytosol
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part FBgn0014388
GO:0045177
IEA
PLAZA Integrative Orthologyapical part of cell FBgn0014388
GO:0098562
IEA
PLAZA Integrative Orthologycytoplasmic side of membrane FBgn0014388
GO:0098552
IEA
PLAZA Integrative Orthologyside of membrane FBgn0014388
GO:0044459
IEA
PLAZA Integrative Orthologyplasma membrane part FBgn0014388
GO:0009898
IEA
PLAZA Integrative Orthologycytoplasmic side of plasma membrane FBgn0014388

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR007875Sprouty
IPR030783Protein sprouty homologue 1

No MapMan annotations defined for this gene.
KeggID Description
K04704SPRY1; protein sprouty homolog 1
No chloroplast target sequence found.