Gene: ENSG00000163751 (Homo sapiens)

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Gene Identifier
ENSG00000163751
Transcript Identifier
ENST00000296046
Gene Type
Coding gene
Location
3 : 148865308-148896707 : positive

Family Information

Homologous gene family
HOM02SEM001136
(45 genes in 8 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
carboxypeptidase A3 (mast cell)

Identifiers

Type Value
pidENSP00000296046
HGNC2298
UniprotP15088
RefSeq_mRNANM_001870.2
EMBLCHEMBL2645
EMBLAC092979
EMBLBC012613
EMBLM27717
EMBLM73716
EMBLM73717
EMBLM73718
EMBLM73719
EMBLM73720
EMBLS40234

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006508
TAS
Genome Projectproteolysis
GO:0006508
TAS
Gene Ontologyproteolysis1
GO:0002003
TAS
Genome Projectangiotensin maturation
GO:0002003
TAS
Gene Ontologyangiotensin maturation
GO:0050789
IEA
PLAZA Integrative Orthologyregulation of biological process ENSG00000080618
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0259149
GO:0045165
IEA
PLAZA Integrative Orthologycell fate commitment FBgn0259149
GO:0046331
IEA
PLAZA Integrative Orthologylateral inhibition FBgn0259149
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0259149
GO:1901575
IEA
PLAZA Integrative Orthologyorganic substance catabolic process ENSG00000158516
GO:0044267
IEA
PLAZA Integrative Orthologycellular protein metabolic process ENSG00000158516
GO:0030163
IEA
PLAZA Integrative Orthologyprotein catabolic process ENSG00000158516
GO:0050776
IEA
PLAZA Integrative Orthologyregulation of immune response ENSG00000080618
GO:0050896
IEA
PLAZA Integrative Orthologyresponse to stimulus ENSG00000080618
GO:0050778
IEA
PLAZA Integrative Orthologypositive regulation of immune response ENSG00000080618
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0259149
GO:0044265
IEA
PLAZA Integrative Orthologycellular macromolecule catabolic process ENSG00000158516
GO:0044260
IEA
PLAZA Integrative Orthologycellular macromolecule metabolic process ENSG00000158516
GO:0030449
IEA
PLAZA Integrative Orthologyregulation of complement activation ENSG00000080618
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus ENSG00000080618
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus ENSG00000080618
GO:0002697
IEA
PLAZA Integrative Orthologyregulation of immune effector process ENSG00000080618
GO:0007039
IEA
PLAZA Integrative Orthologyprotein catabolic process in the vacuole ENSG00000158516
GO:0044257
IEA
PLAZA Integrative Orthologycellular protein catabolic process ENSG00000158516
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0032144
GO:0007399
IEA
PLAZA Integrative Orthologynervous system development FBgn0032144
GO:1901565
IEA
PLAZA Integrative Orthologyorganonitrogen compound catabolic process ENSG00000158516
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0032144
GO:0007154
IEA
PLAZA Integrative Orthologycell communication FBgn0259149
GO:0009056
IEA
PLAZA Integrative Orthologycatabolic process ENSG00000158516
GO:0009057
IEA
PLAZA Integrative Orthologymacromolecule catabolic process ENSG00000158516
GO:0023052
IEA
PLAZA Integrative Orthologysignaling FBgn0259149
GO:0048731
IEA
PLAZA Integrative Orthologysystem development FBgn0032144
GO:0002920
IEA
PLAZA Integrative Orthologyregulation of humoral immune response ENSG00000080618
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process ENSG00000080618
GO:0044248
IEA
PLAZA Integrative Orthologycellular catabolic process ENSG00000158516
GO:0002253
IEA
PLAZA Integrative Orthologyactivation of immune response ENSG00000080618
GO:0002252
IEA
PLAZA Integrative Orthologyimmune effector process ENSG00000080618
GO:0007267
IEA
PLAZA Integrative Orthologycell-cell signaling FBgn0259149
GO:0006959
IEA
PLAZA Integrative Orthologyhumoral immune response ENSG00000080618
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response ENSG00000080618
GO:0006956
IEA
PLAZA Integrative Orthologycomplement activation ENSG00000080618
GO:0002684
IEA
PLAZA Integrative Orthologypositive regulation of immune system process ENSG00000080618
GO:0048518
IEA
PLAZA Integrative Orthologypositive regulation of biological process ENSG00000080618
GO:0002682
IEA
PLAZA Integrative Orthologyregulation of immune system process ENSG00000080618
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0032144
GO:0045168
IEA
PLAZA Integrative Orthologycell-cell signaling involved in cell fate commitment FBgn0259149

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0004181
EXP
TAS, NAS
Genome Projectmetallocarboxypeptidase activity
GO:0004181
EXP
TAS, NAS
Gene Ontologymetallocarboxypeptidase activity1 2 3
GO:0005515
IEA
PLAZA Integrative Orthologyprotein binding ENSG00000091704

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030141
NAS
Genome Projectsecretory granule
GO:0030141
NAS
Gene Ontologysecretory granule3
GO:0030133
IEA
Genome Projecttransport vesicle
GO:0005615
IBA
Genome Projectextracellular space
GO:0005576
TAS
Genome Projectextracellular region
GO:0005576
TAS
Gene Ontologyextracellular region4
GO:0062023
Gene Ontologycollagen-containing extracellular matrix5
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery ENSG00000144410
GO:0016020
IEA
PLAZA Integrative Orthologymembrane ENSG00000144410
GO:0000322
IEA
PLAZA Integrative Orthologystorage vacuole YHR132C
GO:0000323
IEA
PLAZA Integrative Orthologylytic vacuole YHR132C
GO:0044425
IEA
PLAZA Integrative Orthologymembrane part ENSG00000144410
GO:0000324
IEA
PLAZA Integrative Orthologyfungal-type vacuole YHR132C
GO:0005783
IEA
PLAZA Integrative Orthologyendoplasmic reticulum SPBC337.07c
GO:0070062
IEA
PLAZA Integrative Orthologyextracellular exosome ENSG00000080618
GO:0044459
IEA
PLAZA Integrative Orthologyplasma membrane part ENSG00000144410
GO:0060102
IEA
PLAZA Integrative Orthologycollagen and cuticulin-based cuticle extracellular matrix WBGene00011235
GO:0031225
IEA
PLAZA Integrative Orthologyanchored component of membrane ENSG00000144410
GO:0031224
IEA
PLAZA Integrative Orthologyintrinsic component of membrane ENSG00000144410
GO:0031226
IEA
PLAZA Integrative Orthologyintrinsic component of plasma membrane ENSG00000144410
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane ENSG00000144410
GO:0043230
IEA
PLAZA Integrative Orthologyextracellular organelle ENSG00000080618
GO:0043231
IEA
PLAZA Integrative Orthologyintracellular membrane-bounded organelle SPBC337.07c
GO:0046658
IEA
PLAZA Integrative Orthologyanchored component of plasma membrane ENSG00000144410
GO:1903561
IEA
PLAZA Integrative Orthologyextracellular vesicle ENSG00000080618

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000834Peptidase M14, carboxypeptidase A
IPR003146Carboxypeptidase, activation peptide
IPR034253Carboxypeptidase B, carboxypeptidase domain

No MapMan annotations defined for this gene.
KeggID Description
K08780CPA3; carboxypeptidase A3
No chloroplast target sequence found.