Gene: ENSG00000163485 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000163485
Transcript Identifier
ENST00000337894
Gene Type
Coding gene
Location
1 : 203128842-203165900 : positive

Family Information

Homologous gene family
HOM02SEM000364
(94 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM010794
(6 genes in 3 species)
specific family

Descriptions

gene_descr
adenosine A1 receptor

Identifiers

Type Value
pidENSP00000338435
HGNC262
UniprotP30542
RefSeq_mRNANM_000674.2
EMBLCHEMBL226
EMBLAB004662
EMBLAC105940
EMBLAK127752
EMBLAK289928
EMBLAY136746
EMBLBC026340
EMBLBT019854
EMBLCH471067
EMBLCR541749
EMBLEF057066
EMBLL22214
EMBLS45235
EMBLS56143
EMBLX68485

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1900453
IEA
Genome Projectnegative regulation of long-term synaptic depression
GO:0097756
IEA
Genome Projectnegative regulation of blood vessel diameter
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:0097190
TAS
Gene Ontologyapoptotic signaling pathway1
GO:0070256
IEA
Genome Projectnegative regulation of mucus secretion
GO:0060087
IEA
Genome Projectrelaxation of vascular smooth muscle
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0055118
IEA
Genome Projectnegative regulation of cardiac muscle contraction
GO:0051967
IEA
Genome Projectnegative regulation of synaptic transmission, glutamatergic
GO:0051930
IEA
Genome Projectregulation of sensory perception of pain
GO:0050995
IEA
Genome Projectnegative regulation of lipid catabolic process
GO:0050965
IEA
Genome Projectdetection of temperature stimulus involved in sensory perception of pain
GO:0050890
IEA
Genome Projectcognition
GO:0046888
IEA
Genome Projectnegative regulation of hormone secretion
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0045776
IEA
Genome Projectnegative regulation of blood pressure
GO:0045741
IEA
Genome Projectpositive regulation of epidermal growth factor-activated receptor activity
GO:0043268
IEA
Genome Projectpositive regulation of potassium ion transport
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0042323
IEA
Genome Projectnegative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0035814
IEA
Genome Projectnegative regulation of renal sodium excretion
GO:0035307
IEA
Genome Projectpositive regulation of protein dephosphorylation
GO:0032900
IEA
Genome Projectnegative regulation of neurotrophin production
GO:0032244
IEA
Genome Projectpositive regulation of nucleoside transport
GO:0032229
IEA
Genome Projectnegative regulation of synaptic transmission, GABAergic
GO:0016042
IEA
Genome Projectlipid catabolic process
GO:0014050
IEA
Genome Projectnegative regulation of glutamate secretion
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0007399
TAS
Genome Projectnervous system development
GO:0007399
TAS
Gene Ontologynervous system development2
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0007267
TAS
Gene Ontologycell-cell signaling1
GO:0007193
IEA
Genome Projectadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007165
TAS
Gene Ontologysignal transduction3
GO:0006954
TAS
Genome Projectinflammatory response
GO:0006954
TAS
Gene Ontologyinflammatory response4
GO:0006909
TAS
Genome Projectphagocytosis
GO:0006909
TAS
Gene Ontologyphagocytosis4
GO:0006612
IEA
Genome Projectprotein targeting to membrane
GO:0003093
IEA
Genome Projectregulation of glomerular filtration
GO:0002793
IEA
Genome Projectpositive regulation of peptide secretion
GO:0002686
IEA
Genome Projectnegative regulation of leukocyte migration
GO:0002674
IEA
Genome Projectnegative regulation of acute inflammatory response
GO:0002087
IEA
Genome Projectregulation of respiratory gaseous exchange by neurological system process
GO:0001973
IEA
Genome Projectadenosine receptor signaling pathway
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001659
IEA
Genome Projecttemperature homeostasis
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0007186
TAS
Gene OntologyG protein-coupled receptor signaling pathway
GO:0019932
IEA
PLAZA Integrative Orthologysecond-messenger-mediated signaling FBgn0039747
GO:0019933
IEA
PLAZA Integrative OrthologycAMP-mediated signaling FBgn0039747
GO:0031326
IEA
PLAZA Integrative Orthologyregulation of cellular biosynthetic process ENSG00000282608
GO:0072511
IEA
PLAZA Integrative Orthologydivalent inorganic cation transport FBgn0039747
GO:0032774
IEA
PLAZA Integrative OrthologyRNA biosynthetic process ENSG00000282608
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0039747
GO:0044271
IEA
PLAZA Integrative Orthologycellular nitrogen compound biosynthetic process ENSG00000282608
GO:0005975
IEA
PLAZA Integrative Orthologycarbohydrate metabolic process FBgn0039747
GO:0006109
IEA
PLAZA Integrative Orthologyregulation of carbohydrate metabolic process FBgn0039747
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0039747
GO:0090281
IEA
PLAZA Integrative Orthologynegative regulation of calcium ion import FBgn0039747
GO:0006355
IEA
PLAZA Integrative Orthologyregulation of transcription, DNA-templated ENSG00000282608
GO:1901576
IEA
PLAZA Integrative Orthologyorganic substance biosynthetic process ENSG00000282608
GO:0031098
IEA
PLAZA Integrative Orthologystress-activated protein kinase signaling cascade ENSG00000170425
GO:0006351
IEA
PLAZA Integrative Orthologytranscription, DNA-templated ENSG00000282608
GO:0034645
IEA
PLAZA Integrative Orthologycellular macromolecule biosynthetic process ENSG00000282608
GO:0007190
IEA
PLAZA Integrative Orthologyactivation of adenylate cyclase activity ENSG00000282608
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process ENSG00000282608
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress ENSG00000170425
GO:0010556
IEA
PLAZA Integrative Orthologyregulation of macromolecule biosynthetic process ENSG00000282608
GO:0006816
IEA
PLAZA Integrative Orthologycalcium ion transport FBgn0039747
GO:0018130
IEA
PLAZA Integrative Orthologyheterocycle biosynthetic process ENSG00000282608
GO:0016070
IEA
PLAZA Integrative OrthologyRNA metabolic process ENSG00000282608
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process ENSG00000282608
GO:1903506
IEA
PLAZA Integrative Orthologyregulation of nucleic acid-templated transcription ENSG00000282608
GO:0009058
IEA
PLAZA Integrative Orthologybiosynthetic process ENSG00000282608
GO:0009059
IEA
PLAZA Integrative Orthologymacromolecule biosynthetic process ENSG00000282608
GO:0009611
IEA
PLAZA Integrative Orthologyresponse to wounding ENSG00000282608
GO:0090279
IEA
PLAZA Integrative Orthologyregulation of calcium ion import FBgn0039747
GO:1901362
IEA
PLAZA Integrative Orthologyorganic cyclic compound biosynthetic process ENSG00000282608
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process ENSG00000282608
GO:0070509
IEA
PLAZA Integrative Orthologycalcium ion import FBgn0039747
GO:0019219
IEA
PLAZA Integrative Orthologyregulation of nucleobase-containing compound metabolic process ENSG00000282608
GO:0019935
IEA
PLAZA Integrative Orthologycyclic-nucleotide-mediated signaling FBgn0039747
GO:0044092
IEA
PLAZA Integrative Orthologynegative regulation of molecular function ENSG00000282608
GO:0019438
IEA
PLAZA Integrative Orthologyaromatic compound biosynthetic process ENSG00000282608
GO:0097659
IEA
PLAZA Integrative Orthologynucleic acid-templated transcription ENSG00000282608
GO:0034654
IEA
PLAZA Integrative Orthologynucleobase-containing compound biosynthetic process ENSG00000282608
GO:0010467
IEA
PLAZA Integrative Orthologygene expression ENSG00000282608
GO:0010468
IEA
PLAZA Integrative Orthologyregulation of gene expression ENSG00000282608
GO:0051252
IEA
PLAZA Integrative Orthologyregulation of RNA metabolic process ENSG00000282608
GO:0006968
IEA
PLAZA Integrative Orthologycellular defense response ENSG00000170425
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process ENSG00000282608
GO:0009889
IEA
PLAZA Integrative Orthologyregulation of biosynthetic process ENSG00000282608
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process ENSG00000282608
GO:0044249
IEA
PLAZA Integrative Orthologycellular biosynthetic process ENSG00000282608
GO:0007189
IEA
PLAZA Integrative Orthologyadenylate cyclase-activating G protein-coupled receptor signaling pathway FBgn0039747
GO:0043433
IEA
PLAZA Integrative Orthologynegative regulation of DNA-binding transcription factor activity ENSG00000282608
GO:0032088
IEA
PLAZA Integrative Orthologynegative regulation of NF-kappaB transcription factor activity ENSG00000282608
GO:2001141
IEA
PLAZA Integrative Orthologyregulation of RNA biosynthetic process ENSG00000282608
GO:0070838
IEA
PLAZA Integrative Orthologydivalent metal ion transport FBgn0039747
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process ENSG00000282608
GO:0051403
IEA
PLAZA Integrative Orthologystress-activated MAPK cascade ENSG00000170425
GO:0051924
IEA
PLAZA Integrative Orthologyregulation of calcium ion transport FBgn0039747
GO:0051926
IEA
PLAZA Integrative Orthologynegative regulation of calcium ion transport FBgn0039747
GO:2000112
IEA
PLAZA Integrative Orthologyregulation of cellular macromolecule biosynthetic process ENSG00000282608
GO:0000187
IEA
PLAZA Integrative Orthologyactivation of MAPK activity ENSG00000170425
GO:0007611
IEA
PLAZA Integrative Orthologylearning or memory FBgn0039747
GO:0051090
IEA
PLAZA Integrative Orthologyregulation of DNA-binding transcription factor activity ENSG00000282608
GO:0007612
IEA
PLAZA Integrative Orthologylearning FBgn0039747
GO:0008306
IEA
PLAZA Integrative Orthologyassociative learning FBgn0039747
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0039747
GO:0007254
IEA
PLAZA Integrative OrthologyJNK cascade ENSG00000170425

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0032795
IEA
Genome Projectheterotrimeric G-protein binding
GO:0031683
IEA
Genome ProjectG-protein beta/gamma-subunit complex binding
GO:0031072
IEA
Genome Projectheat shock protein binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding5
GO:0004629
IEA
Genome Projectphospholipase C activity
GO:0001883
IEA
Genome Projectpurine nucleoside binding
GO:0001664
IEA
Genome ProjectG protein-coupled receptor binding
GO:0001609
IEA
Genome ProjectG protein-coupled adenosine receptor activity
GO:0030594
IEA
PLAZA Homology (enrichment)neurotransmitter receptor activity HOM02SEM000364
GO:0008227
IEA
PLAZA Homology (enrichment)G protein-coupled amine receptor activity HOM02SEM000364

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0048786
IEA
Genome Projectpresynaptic active zone
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043195
IEA
Genome Projectterminal bouton
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0042734
IEA
Genome Projectpresynaptic membrane
GO:0030673
IEA
Genome Projectaxolemma
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0005887
TAS
Gene Ontologyintegral component of plasma membrane3
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0005886
IDA
TAS
Gene Ontologyplasma membrane6
GO:0005783
IEA
Genome Projectendoplasmic reticulum

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR001068Adenosine A1 receptor
IPR001634Adenosine receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.
KeggID Description
K04265ADORA1; adenosine receptor A1
No chloroplast target sequence found.