Gene: ENSG00000157500 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000157500
Transcript Identifier
ENST00000288266
Gene Type
Coding gene
Location
3 : 57227884-57269687 : positive

Family Information

Homologous gene family
HOM02SEM041833
(2 genes in 1 species)
specific family

Descriptions

gene_descr
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Identifiers

Type Value
pidENSP00000288266
HGNC24035
UniprotQ9UKG1
RefSeq_mRNANM_012096.2
EMBLAB037849
EMBLAF169797
EMBLAF424738
EMBLBC028599

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097192
TAS
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097192
TAS
Gene Ontologyextrinsic apoptotic signaling pathway in absence of ligand
GO:0046324
IMP
Genome Projectregulation of glucose import
GO:0046324
IMP
Gene Ontologyregulation of glucose import1
GO:0008286
IMP
TAS
Genome Projectinsulin receptor signaling pathway
GO:0008286
IMP
TAS
Gene Ontologyinsulin receptor signaling pathway1 2
GO:0008283
IDA
Genome Projectcell proliferation
GO:0008283
IDA
Gene Ontologycell proliferation3
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007165
TAS
Gene Ontologysignal transduction4
GO:0007049
IEA
Genome Projectcell cycle
GO:1903076
IMP
Gene Ontologyregulation of protein localization to plasma membrane1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043422
IPI
Genome Projectprotein kinase B binding
GO:0043422
IPI
Gene Ontologyprotein kinase B binding1
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding5 6 7
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding3 4 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0044877
IPI
Gene Ontologyprotein-containing complex binding3

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016581
IDA
Genome ProjectNuRD complex
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome19 20
GO:0031901
IEA
Genome Projectearly endosome membrane
GO:0012506
IDA
Genome Projectvesicle membrane
GO:0012506
IDA
Gene Ontologyvesicle membrane1
GO:0010008
IDA
TAS
Genome Projectendosome membrane
GO:0010008
IDA
TAS
Gene Ontologyendosome membrane3
GO:0005829
IDA
Genome Projectcytosol
GO:0005829
IDA
Gene Ontologycytosol1
GO:0005769
ISS
Genome Projectearly endosome
GO:0005769
ISS
Gene Ontologyearly endosome
GO:0005737
IC
Genome Projectcytoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001849Pleckstrin homology domain
IPR006020PTB/PI domain
IPR011993PH-like domain superfamily
IPR027267AH/BAR domain superfamily

No MapMan annotations defined for this gene.
KeggID Description
K08733APPL1, DIP13A; DCC-interacting protein 13 alpha
No chloroplast target sequence found.