Gene: ENSG00000156463 (Homo sapiens)

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Gene Identifier
ENSG00000156463
Transcript Identifier
ENST00000511217
Gene Type
Coding gene
Location
5 : 145937929-146062701 : positive

Family Information

Homologous gene family
HOM02SEM004883
(17 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM008663
(9 genes in 3 species)
specific family

Descriptions

gene_descr
SH3 domain containing ring finger 2

Identifiers

Type Value
pidENSP00000424497
HGNC26299
UniprotQ8TEC5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0010923
IDA
Genome Projectnegative regulation of phosphatase activity
GO:0010923
IDA
Gene Ontologynegative regulation of phosphatase activity1
GO:0051865
IMP
Gene Ontologyprotein autoubiquitination2
GO:0046330
IMP
Gene Ontologypositive regulation of JNK cascade2
GO:0046329
ISS
Gene Ontologynegative regulation of JNK cascade
GO:0043066
IMP
ISS
Gene Ontologynegative regulation of apoptotic process2
GO:0032436
IMP
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process3
GO:0031397
IMP
Gene Ontologynegative regulation of protein ubiquitination2
GO:0030335
IMP
Gene Ontologypositive regulation of cell migration2
GO:2001234
IEA
PLAZA Integrative Orthologynegative regulation of apoptotic signaling pathway ENSG00000154447
GO:0010243
IEA
PLAZA Integrative Orthologyresponse to organonitrogen compound FBgn0040294
GO:0098609
IEA
PLAZA Integrative Orthologycell-cell adhesion FBgn0040294
GO:2001233
IEA
PLAZA Integrative Orthologyregulation of apoptotic signaling pathway ENSG00000154447
GO:0030155
IEA
PLAZA Integrative Orthologyregulation of cell adhesion FBgn0040294
GO:2001236
IEA
PLAZA Integrative Orthologyregulation of extrinsic apoptotic signaling pathway ENSG00000154447
GO:2001237
IEA
PLAZA Integrative Orthologynegative regulation of extrinsic apoptotic signaling pathway ENSG00000154447
GO:0045087
IEA
PLAZA Integrative Orthologyinnate immune response FBgn0040294
GO:0048598
IEA
PLAZA Integrative Orthologyembryonic morphogenesis FBgn0040294
GO:0009617
IEA
PLAZA Integrative Orthologyresponse to bacterium FBgn0040294
GO:0007568
IEA
PLAZA Integrative Orthologyaging FBgn0040294
GO:0022610
IEA
PLAZA Integrative Orthologybiological adhesion FBgn0040294
GO:0006952
IEA
PLAZA Integrative Orthologydefense response FBgn0040294
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway ENSG00000154447
GO:1901698
IEA
PLAZA Integrative Orthologyresponse to nitrogen compound FBgn0040294
GO:0008258
IEA
PLAZA Integrative Orthologyhead involution FBgn0040294
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process FBgn0040294
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process FBgn0040294
GO:0010951
IEA
PLAZA Integrative Orthologynegative regulation of endopeptidase activity ENSG00000154447
GO:0051704
IEA
PLAZA Integrative Orthologymulti-organism process FBgn0040294
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0040294
GO:0060429
IEA
PLAZA Integrative Orthologyepithelium development FBgn0040294
GO:0009607
IEA
PLAZA Integrative Orthologyresponse to biotic stimulus FBgn0040294
GO:0007155
IEA
PLAZA Integrative Orthologycell adhesion FBgn0040294
GO:0045861
IEA
PLAZA Integrative Orthologynegative regulation of proteolysis ENSG00000154447
GO:0009653
IEA
PLAZA Integrative Orthologyanatomical structure morphogenesis FBgn0040294
GO:0097190
IEA
PLAZA Integrative Orthologyapoptotic signaling pathway ENSG00000154447
GO:0097191
IEA
PLAZA Integrative Orthologyextrinsic apoptotic signaling pathway ENSG00000154447
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development FBgn0040294
GO:0051707
IEA
PLAZA Integrative Orthologyresponse to other organism FBgn0040294
GO:0007390
IEA
PLAZA Integrative Orthologygerm-band shortening FBgn0040294
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development FBgn0040294
GO:0043207
IEA
PLAZA Integrative Orthologyresponse to external biotic stimulus FBgn0040294
GO:0052547
IEA
PLAZA Integrative Orthologyregulation of peptidase activity ENSG00000154447
GO:0007391
IEA
PLAZA Integrative Orthologydorsal closure FBgn0040294
GO:0010466
IEA
PLAZA Integrative Orthologynegative regulation of peptidase activity ENSG00000154447
GO:0002009
IEA
PLAZA Integrative Orthologymorphogenesis of an epithelium FBgn0040294
GO:0052548
IEA
PLAZA Integrative Orthologyregulation of endopeptidase activity ENSG00000154447
GO:0043281
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity involved in apoptotic process ENSG00000154447
GO:0002376
IEA
PLAZA Integrative Orthologyimmune system process FBgn0040294
GO:0009888
IEA
PLAZA Integrative Orthologytissue development FBgn0040294
GO:0048729
IEA
PLAZA Integrative Orthologytissue morphogenesis FBgn0040294
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0040294
GO:0010033
IEA
PLAZA Integrative Orthologyresponse to organic substance FBgn0040294
GO:2000116
IEA
PLAZA Integrative Orthologyregulation of cysteine-type endopeptidase activity ENSG00000154447
GO:2000117
IEA
PLAZA Integrative Orthologynegative regulation of cysteine-type endopeptidase activity ENSG00000154447
GO:0016331
IEA
PLAZA Integrative Orthologymorphogenesis of embryonic epithelium FBgn0040294
GO:0010259
IEA
PLAZA Integrative Orthologymulticellular organism aging FBgn0040294
GO:0001700
IEA
PLAZA Integrative Orthologyembryonic development via the syncytial blastoderm FBgn0040294
GO:0043154
IEA
PLAZA Integrative Orthologynegative regulation of cysteine-type endopeptidase activity involved in apoptotic process ENSG00000154447
GO:0006955
IEA
PLAZA Integrative Orthologyimmune response FBgn0040294
GO:0002237
IEA
PLAZA Integrative Orthologyresponse to molecule of bacterial origin FBgn0040294
GO:0008340
IEA
PLAZA Integrative Orthologydetermination of adult lifespan FBgn0040294
GO:1901700
IEA
PLAZA Integrative Orthologyresponse to oxygen-containing compound FBgn0040294
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching FBgn0040294
GO:0022407
IEA
PLAZA Integrative Orthologyregulation of cell-cell adhesion FBgn0040294
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development FBgn0040294
GO:0032494
IEA
PLAZA Integrative Orthologyresponse to peptidoglycan FBgn0040294

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0019902
IDA
Genome Projectphosphatase binding
GO:0019902
IDA
Gene Ontologyphosphatase binding1
GO:0016740
IEA
Genome Projecttransferase activity
GO:0008157
IDA
Genome Projectprotein phosphatase 1 binding
GO:0008157
IDA
Gene Ontologyprotein phosphatase 1 binding4
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 4 5 6
GO:0004864
IEA
Genome Projectprotein phosphatase inhibitor activity
GO:0061630
IMP
Gene Ontologyubiquitin protein ligase activity2
GO:0019900
IEA
PLAZA Integrative Orthologykinase binding FBgn0040294
GO:0019901
IEA
PLAZA Integrative Orthologyprotein kinase binding FBgn0040294

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005654
IDA
Gene Ontologynucleoplasm
GO:0005634
IDA
Gene Ontologynucleus2
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm ENSG00000154447
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part ENSG00000154447
GO:0005829
IEA
PLAZA Integrative Orthologycytosol ENSG00000154447

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001452SH3 domain
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017907Zinc finger, RING-type, conserved site
IPR027370RING-type zinc-finger, LisH dimerisation motif
IPR028511E3 ubiquitin-protein ligase SH3RF2

No MapMan annotations defined for this gene.
KeggID Description
K12171SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF
No chloroplast target sequence found.