Gene: ENSG00000152457 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000152457
Transcript Identifier
ENST00000378278
Gene Type
Coding gene
Location
10 : 14908408-14954010 : negative

Family Information

Homologous gene family
HOM02SEM001209
(44 genes in 24 species)
specific family

Descriptions

gene_descr
DNA cross-link repair 1C

Identifiers

Type Value
pidENSP00000367527
HGNC17642
UniprotQ96SD1
RefSeq_mRNANM_001033855.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0090305
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:0036297
IBA
Genome Projectinterstrand cross-link repair
GO:0033151
IEA
Genome ProjectV(D)J recombination
GO:0031848
IBA
Genome Projectprotection from non-homologous end joining at telomere
GO:0030183
IEA
Genome ProjectB cell differentiation
GO:0010212
IEA
Genome Projectresponse to ionizing radiation
GO:0006303
IBA
TAS
Genome Projectdouble-strand break repair via nonhomologous end joining
GO:0006303
TAS
Gene Ontologydouble-strand break repair via nonhomologous end joining
GO:0002250
IEA
Genome Projectadaptive immune response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0035312
IBA
Genome Project5'-3' exodeoxyribonuclease activity
GO:0008409
IDA
Genome Project5'-3' exonuclease activity
GO:0008409
IDA
Gene Ontology5'-3' exonuclease activity1
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 4
GO:0004519
TAS
Genome Projectendonuclease activity
GO:0004519
TAS
Gene Ontologyendonuclease activity
GO:0003684
IBA
Genome Projectdamaged DNA binding
GO:0000014
IDA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0000014
IDA
Gene Ontologysingle-stranded DNA endodeoxyribonuclease activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0070419
IDA
Genome Projectnonhomologous end joining complex
GO:0070419
IDA
Gene Ontologynonhomologous end joining complex4
GO:0005794
IDA
Genome ProjectGolgi apparatus
GO:0005794
IDA
Gene OntologyGolgi apparatus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0000784
IBA
Genome Projectnuclear chromosome, telomeric region

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001279Metallo-beta-lactamase
IPR011084DNA repair metallo-beta-lactamase

No MapMan annotations defined for this gene.
KeggID Description
K10887DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein
No chloroplast target sequence found.