Gene: ENSG00000151876 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000151876
Transcript Identifier
ENST00000281623
Gene Type
Coding gene
Location
5 : 41925310-41941281 : positive

Family Information

Homologous gene family
HOM02SEM123616
(orphan gene)
specific family

Descriptions

gene_descr
F-box protein 4

Identifiers

Type Value
pidENSP00000281623
HGNC13583
UniprotQ9UKT5
RefSeq_mRNANM_012176.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2000001
IEA
Genome Projectregulation of DNA damage checkpoint
GO:1902916
IEA
Genome Projectpositive regulation of protein polyubiquitination
GO:1900181
IEA
Genome Projectnegative regulation of protein localization to nucleus
GO:0071479
IEA
Genome Projectcellular response to ionizing radiation
GO:0048147
IEA
Genome Projectnegative regulation of fibroblast proliferation
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0043687
TAS
Gene Ontologypost-translational protein modification
GO:0035726
IEA
Genome Projectcommon myeloid progenitor cell proliferation
GO:0032212
IMP
IC
Genome Projectpositive regulation of telomere maintenance via telomerase
GO:0032212
IMP
IC
Gene Ontologypositive regulation of telomere maintenance via telomerase1 2
GO:0031648
IEA
Genome Projectprotein destabilization
GO:0031647
IDA, IMP
Genome Projectregulation of protein stability
GO:0031647
IDA, IMP
Gene Ontologyregulation of protein stability1 2
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IDA
Gene Ontologypositive regulation of protein ubiquitination2
GO:0031146
IDA
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031146
IDA
Gene OntologySCF-dependent proteasomal ubiquitin-dependent protein catabolic process3
GO:0019725
IEA
Genome Projectcellular homeostasis
GO:0016567
IDA
TAS
Genome Projectprotein ubiquitination
GO:0016567
IDA
TAS
Gene Ontologyprotein ubiquitination1 2 4
GO:0010608
IEA
Genome Projectposttranscriptional regulation of gene expression
GO:0007568
IEA
Genome Projectaging
GO:0000209
IDA
TAS
Genome Projectprotein polyubiquitination
GO:0000209
IDA
TAS
Gene Ontologyprotein polyubiquitination5

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061630
IEA
Genome Projectubiquitin protein ligase activity
GO:0042803
IPI
Genome Projectprotein homodimerization activity
GO:0042803
IPI
Gene Ontologyprotein homodimerization activity5
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 3 5 6 7 8 9 10
GO:0004842
EXP, IDA
TAS
Genome Projectubiquitin-protein transferase activity
GO:0004842
EXP, IDA
TAS
Gene Ontologyubiquitin-protein transferase activity4 11

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019005
IDA
Genome ProjectSCF ubiquitin ligase complex
GO:0019005
IDA
Gene OntologySCF ubiquitin ligase complex5
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm12
GO:0000151
IDA
Genome Projectubiquitin ligase complex
GO:0000151
IDA
Gene Ontologyubiquitin ligase complex4

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001810F-box domain

No MapMan annotations defined for this gene.
KeggID Description
K10291FBXO4; F-box protein 4
No chloroplast target sequence found.