Gene: ENSG00000147133 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000147133
Transcript Identifier
ENST00000423759
Gene Type
Coding gene
Location
X : 71366315-71464046 : positive

Family Information

Homologous gene family
HOM02SEM001680
(36 genes in 22 species)
specific family

Descriptions

gene_descr
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa

Identifiers

Type Value
pidENSP00000406549
HGNC11535
UniprotP21675
RefSeq_mRNANM_001286074.1

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2000825
IDA
Genome Projectpositive regulation of androgen receptor activity
GO:2000825
IDA
Gene Ontologypositive regulation of androgen receptor activity1
GO:2000059
IMP
Genome Projectnegative regulation of ubiquitin-dependent protein catabolic process
GO:2000059
IMP
Gene Ontologynegative regulation of ubiquitin-dependent protein catabolic process2
GO:1905524
IDA
Genome Projectnegative regulation of protein autoubiquitination
GO:1905524
IDA
Gene Ontologynegative regulation of protein autoubiquitination2
GO:1903026
IDA
Genome Projectnegative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1903026
IDA
Gene Ontologynegative regulation of RNA polymerase II regulatory region sequence-specific DNA binding3
GO:1902806
TAS
Genome Projectregulation of cell cycle G1/S phase transition
GO:1902806
TAS
Gene Ontologyregulation of cell cycle G1/S phase transition4
GO:1901796
TAS
Genome Projectregulation of signal transduction by p53 class mediator
GO:1901796
TAS
Gene Ontologyregulation of signal transduction by p53 class mediator
GO:0071318
IDA
Genome Projectcellular response to ATP
GO:0071318
IDA
Gene Ontologycellular response to ATP3
GO:0060261
ISS
Genome Projectpositive regulation of transcription initiation from RNA polymerase II promoter
GO:0060261
ISS
Gene Ontologypositive regulation of transcription initiation from RNA polymerase II promoter
GO:0060260
NAS
Genome Projectregulation of transcription initiation from RNA polymerase II promoter
GO:0060260
NAS
Gene Ontologyregulation of transcription initiation from RNA polymerase II promoter5
GO:0051123
ISS
Genome ProjectRNA polymerase II preinitiation complex assembly
GO:0051123
ISS
Gene OntologyRNA polymerase II preinitiation complex assembly
GO:0050821
IDA
Genome Projectprotein stabilization
GO:0050821
IDA
Gene Ontologyprotein stabilization2
GO:0046777
IDA
TAS
Genome Projectprotein autophosphorylation
GO:0046777
IDA
TAS
Gene Ontologyprotein autophosphorylation1 3 6 7
GO:0045944
IDA, IGI
Genome Projectpositive regulation of transcription by RNA polymerase II
GO:0045944
IDA, IGI
Gene Ontologypositive regulation of transcription by RNA polymerase II8 9
GO:0045943
IGI
Genome Projectpositive regulation of transcription by RNA polymerase I
GO:0045943
IGI
Gene Ontologypositive regulation of transcription by RNA polymerase I4
GO:0036369
IDA
Genome Projecttranscription factor catabolic process
GO:0036369
IDA
Gene Ontologytranscription factor catabolic process1
GO:0034644
IDA
Genome Projectcellular response to UV
GO:0034644
IDA
Gene Ontologycellular response to UV3
GO:0032436
IDA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IDA
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process7
GO:0032092
IDA
Genome Projectpositive regulation of protein binding
GO:0032092
IDA
Gene Ontologypositive regulation of protein binding2
GO:0030901
IGI
Genome Projectmidbrain development
GO:0030901
IGI
Gene Ontologymidbrain development10
GO:0018107
IDA
Genome Projectpeptidyl-threonine phosphorylation
GO:0018107
IDA
Gene Ontologypeptidyl-threonine phosphorylation3 7
GO:0018105
IDA
Genome Projectpeptidyl-serine phosphorylation
GO:0018105
IDA
Gene Ontologypeptidyl-serine phosphorylation6
GO:0016573
IEA
Genome Projecthistone acetylation
GO:0016032
IEA
Genome Projectviral process
GO:0010767
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010629
IMP
Gene Ontologynegative regulation of gene expression2
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0007049
IEA
Genome Projectcell cycle
GO:0006974
IDA
IC
Genome Projectcellular response to DNA damage stimulus
GO:0006974
IDA
IC
Gene Ontologycellular response to DNA damage stimulus3 7
GO:0006468
IDA
Genome Projectprotein phosphorylation
GO:0006468
IDA
Gene Ontologyprotein phosphorylation11
GO:0006368
TAS
Genome Projecttranscription elongation from RNA polymerase II promoter
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006367
TAS
Gene Ontologytranscription initiation from RNA polymerase II promoter
GO:0006366
TAS
Genome Projecttranscription by RNA polymerase II
GO:0006366
TAS
Gene Ontologytranscription by RNA polymerase II
GO:0006352
ISS
Genome ProjectDNA-templated transcription, initiation
GO:0006352
ISS
Gene OntologyDNA-templated transcription, initiation
GO:0000209
IDA
Genome Projectprotein polyubiquitination
GO:0000209
IDA
Gene Ontologyprotein polyubiquitination1
GO:0043433
IC
Gene Ontologynegative regulation of DNA-binding transcription factor activity3
GO:0010768
IMP
Gene Ontologynegative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage3
GO:0006511
IDA
Gene Ontologyubiquitin-dependent protein catabolic process1
GO:0006355
TAS
Gene Ontologyregulation of transcription, DNA-templated12
GO:0019953
IEA
PLAZA Integrative Orthologysexual reproduction ENSG00000122728
GO:0030154
IEA
PLAZA Integrative Orthologycell differentiation FBgn0010355
GO:0044154
IEA
PLAZA Integrative Orthologyhistone H3-K14 acetylation FBgn0010355
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway FBgn0010355
GO:0097696
IEA
PLAZA Integrative OrthologySTAT cascade FBgn0010355
GO:0048232
IEA
PLAZA Integrative Orthologymale gamete generation ENSG00000122728
GO:0022412
IEA
PLAZA Integrative Orthologycellular process involved in reproduction in multicellular organism ENSG00000122728
GO:0048869
IEA
PLAZA Integrative Orthologycellular developmental process FBgn0010355
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction ENSG00000122728
GO:0007221
IEA
PLAZA Integrative Orthologypositive regulation of transcription of Notch receptor target FBgn0010355
GO:0007166
IEA
PLAZA Integrative Orthologycell surface receptor signaling pathway FBgn0010355
GO:0044764
IEA
PLAZA Integrative Orthologymulti-organism cellular process AT1G32750
GO:0046425
IEA
PLAZA Integrative Orthologyregulation of JAK-STAT cascade FBgn0010355
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process ENSG00000122728
GO:0007140
IEA
PLAZA Integrative Orthologymale meiotic nuclear division ENSG00000122728
GO:0048609
IEA
PLAZA Integrative Orthologymulticellular organismal reproductive process ENSG00000122728
GO:0044703
IEA
PLAZA Integrative Orthologymulti-organism reproductive process ENSG00000122728
GO:0140013
IEA
PLAZA Integrative Orthologymeiotic nuclear division ENSG00000122728
GO:0000280
IEA
PLAZA Integrative Orthologynuclear division ENSG00000122728
GO:0032504
IEA
PLAZA Integrative Orthologymulticellular organism reproduction ENSG00000122728
GO:0051321
IEA
PLAZA Integrative Orthologymeiotic cell cycle ENSG00000122728
GO:0048285
IEA
PLAZA Integrative Orthologyorganelle fission ENSG00000122728
GO:0007259
IEA
PLAZA Integrative OrthologyJAK-STAT cascade FBgn0010355
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0010355
GO:0007276
IEA
PLAZA Integrative Orthologygamete generation ENSG00000122728
GO:1903046
IEA
PLAZA Integrative Orthologymeiotic cell cycle process ENSG00000122728
GO:0009792
IEA
PLAZA Integrative Orthologyembryo development ending in birth or egg hatching WBGene00006382
GO:0009292
IEA
PLAZA Integrative Orthologygenetic transfer AT1G32750
GO:0043966
IEA
PLAZA Integrative Orthologyhistone H3 acetylation FBgn0010355
GO:0009294
IEA
PLAZA Integrative OrthologyDNA mediated transformation AT1G32750
GO:0043967
IEA
PLAZA Integrative Orthologyhistone H4 acetylation FBgn0010355
GO:1904892
IEA
PLAZA Integrative Orthologyregulation of STAT cascade FBgn0010355
GO:0009790
IEA
PLAZA Integrative Orthologyembryo development WBGene00006382

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061628
IPI
Genome ProjectH3K27me3 modified histone binding
GO:0061628
IPI
Gene OntologyH3K27me3 modified histone binding5
GO:0044212
ISS
Genome Projecttranscription regulatory region DNA binding
GO:0044212
ISS
Gene Ontologytranscription regulatory region DNA binding
GO:1905502
IDA
Genome Projectacetyl-CoA binding
GO:1905502
IDA
Gene Ontologyacetyl-CoA binding5
GO:0004402
IDA
NAS
Genome Projecthistone acetyltransferase activity
GO:0004402
IDA
NAS
Gene Ontologyhistone acetyltransferase activity5 13
GO:0070577
IDA
Genome Projectlysine-acetylated histone binding
GO:0070577
IDA
Gene Ontologylysine-acetylated histone binding9
GO:0061631
IDA
Genome Projectubiquitin conjugating enzyme activity
GO:0061631
IDA
Gene Ontologyubiquitin conjugating enzyme activity1
GO:0046982
IPI
Genome Projectprotein heterodimerization activity
GO:0046982
IPI
Gene Ontologyprotein heterodimerization activity12
GO:0043565
ISS
Genome Projectsequence-specific DNA binding
GO:0043565
ISS
Gene Ontologysequence-specific DNA binding
GO:0017025
IPI
Genome ProjectTBP-class protein binding
GO:0017025
IPI
Gene OntologyTBP-class protein binding8
GO:0016301
IDA
Genome Projectkinase activity
GO:0016301
IDA
Gene Ontologykinase activity11
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008134
IPI
Gene Ontologytranscription factor binding6
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 4 11 14 15 16 17 18 19 20 21 22 23 24 25
GO:0004674
EXP, IDA
Genome Projectprotein serine/threonine kinase activity
GO:0004674
EXP, IDA
Gene Ontologyprotein serine/threonine kinase activity6 7
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0003713
IDA
Gene Ontologytranscription coactivator activity9
GO:0002039
IPI
Genome Projectp53 binding
GO:0002039
IPI
Gene Ontologyp53 binding7
GO:0000979
IPI
Genome ProjectRNA polymerase II core promoter sequence-specific DNA binding
GO:0000979
IGI
Gene OntologyRNA polymerase II core promoter sequence-specific DNA binding12
GO:0061629
IPI
Gene OntologyRNA polymerase II sequence-specific DNA-binding transcription factor binding3
GO:0035257
IPI
Gene Ontologynuclear hormone receptor binding1
GO:0000981
ISA
Gene OntologyDNA-binding transcription factor activity, RNA polymerase II-specific
GO:0010485
IEA
PLAZA Integrative OrthologyH4 histone acetyltransferase activity FBgn0010355
GO:0003682
IEA
PLAZA Integrative Orthologychromatin binding YGR274C
GO:0036408
IEA
PLAZA Integrative Orthologyhistone acetyltransferase activity (H3-K14 specific) FBgn0010355
GO:0032947
IEA
PLAZA Integrative Orthologyprotein-containing complex scaffold activity YGR274C
GO:0005198
IEA
PLAZA Integrative Orthologystructural molecule activity YGR274C
GO:0010484
IEA
PLAZA Integrative OrthologyH3 histone acetyltransferase activity FBgn0010355

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005730
IDA
Genome Projectnucleolus
GO:0005730
IDA
Gene Ontologynucleolus4
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm4
GO:0071339
IDA
Genome ProjectMLL1 complex
GO:0071339
IDA
Gene OntologyMLL1 complex26
GO:0005669
IDA
TAS
Genome Projecttranscription factor TFIID complex
GO:0005669
IDA
TAS
Gene Ontologytranscription factor TFIID complex4 5 6 12 27 28
GO:0005667
IPI
Genome Projecttranscription factor complex
GO:0005667
IPI
Gene Ontologytranscription factor complex12
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus4
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0000790
IDA
Gene Ontologynuclear chromatin1 3
GO:0016020
IEA
PLAZA Integrative Orthologymembrane AT3G19040
GO:0005737
IEA
PLAZA Integrative Orthologycytoplasm YGR274C
GO:0044444
IEA
PLAZA Integrative Orthologycytoplasmic part YGR274C
GO:0005829
IEA
PLAZA Integrative Orthologycytosol YGR274C

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001487Bromodomain
IPR009067TAFII-230 TBP-binding
IPR011177Transcription initiation factor TFIID subunit 1, animal
IPR018359Bromodomain, conserved site
IPR022591Transcription initiation factor TFIID subunit 1, domain of unknown function

No MapMan annotations defined for this gene.
KeggID Description
K03125TAF1; transcription initiation factor TFIID subunit 1
No chloroplast target sequence found.