Gene: ENSG00000143207 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000143207
Transcript Identifier
ENST00000367669
Gene Type
Coding gene
Location
1 : 175945153-176206978 : negative

Family Information

Homologous gene family
HOM02SEM002253
(30 genes in 9 species)
specific family

Descriptions

gene_descr
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase

Identifiers

Type Value
pidENSP00000356641
HGNC17440
UniprotQ8NHY2
RefSeq_mRNANM_001286644.1
RefSeq_mRNANM_022457.6
EMBLAF508940
EMBLAF527539
EMBLAK025789
EMBLAK314750
EMBLAL162736
EMBLAL359265
EMBLAL513329
EMBLAL590723
EMBLAY509921
EMBLBC094728
EMBLBK000438
EMBLCH471067
EMBLKJ534928
EMBLKJ535076

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0043687
TAS
Genome Projectpost-translational protein modification
GO:0043687
TAS
Gene Ontologypost-translational protein modification
GO:0032436
IMP
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IMP
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process1
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0010212
IDA
Genome Projectresponse to ionizing radiation
GO:0010212
IDA
Gene Ontologyresponse to ionizing radiation1
GO:0043161
IMP
Gene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process2
GO:2000026
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal development AT2G46340
GO:2000028
IEA
PLAZA Integrative Orthologyregulation of photoperiodism, flowering AT2G46340
GO:0051239
IEA
PLAZA Integrative Orthologyregulation of multicellular organismal process AT2G46340
GO:0051716
IEA
PLAZA Integrative Orthologycellular response to stimulus AT2G46340
GO:0048511
IEA
PLAZA Integrative Orthologyrhythmic process AT2G32950
GO:0006950
IEA
PLAZA Integrative Orthologyresponse to stress AT2G32950
GO:0000003
IEA
PLAZA Integrative Orthologyreproduction AT2G46340
GO:0007602
IEA
PLAZA Integrative Orthologyphototransduction AT2G46340
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization AT2G46340
GO:0043496
IEA
PLAZA Integrative Orthologyregulation of protein homodimerization activity AT5G52250
GO:0022414
IEA
PLAZA Integrative Orthologyreproductive process AT2G46340
GO:0042440
IEA
PLAZA Integrative Orthologypigment metabolic process AT2G32950
GO:0009582
IEA
PLAZA Integrative Orthologydetection of abiotic stimulus AT2G46340
GO:0009583
IEA
PLAZA Integrative Orthologydetection of light stimulus AT2G46340
GO:2000030
IEA
PLAZA Integrative Orthologyregulation of response to red or far red light AT2G46340
GO:0007165
IEA
PLAZA Integrative Orthologysignal transduction AT2G46340
GO:0009585
IEA
PLAZA Integrative Orthologyred, far-red light phototransduction AT2G46340
GO:0010099
IEA
PLAZA Integrative Orthologyregulation of photomorphogenesis AT2G46340
GO:0009581
IEA
PLAZA Integrative Orthologydetection of external stimulus AT2G46340
GO:0032501
IEA
PLAZA Integrative Orthologymulticellular organismal process AT2G46340
GO:0010114
IEA
PLAZA Integrative Orthologyresponse to red light AT2G46340
GO:0048580
IEA
PLAZA Integrative Orthologyregulation of post-embryonic development AT2G46340
GO:0032502
IEA
PLAZA Integrative Orthologydevelopmental process AT2G46340
GO:0034641
IEA
PLAZA Integrative Orthologycellular nitrogen compound metabolic process AT2G32950
GO:0071478
IEA
PLAZA Integrative Orthologycellular response to radiation AT2G46340
GO:0010118
IEA
PLAZA Integrative Orthologystomatal movement AT2G32950
GO:0033554
IEA
PLAZA Integrative Orthologycellular response to stress AT2G32950
GO:0048585
IEA
PLAZA Integrative Orthologynegative regulation of response to stimulus AT2G46340
GO:0010119
IEA
PLAZA Integrative Orthologyregulation of stomatal movement AT2G32950
GO:0046283
IEA
PLAZA Integrative Orthologyanthocyanin-containing compound metabolic process AT2G32950
GO:0009649
IEA
PLAZA Integrative Orthologyentrainment of circadian clock AT2G32950
GO:0048581
IEA
PLAZA Integrative Orthologynegative regulation of post-embryonic development AT2G46340
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus AT2G46340
GO:0046483
IEA
PLAZA Integrative Orthologyheterocycle metabolic process AT2G32950
GO:0048583
IEA
PLAZA Integrative Orthologyregulation of response to stimulus AT2G46340
GO:0009657
IEA
PLAZA Integrative Orthologyplastid organization AT2G46340
GO:0009812
IEA
PLAZA Integrative Orthologyflavonoid metabolic process AT2G32950
GO:0009658
IEA
PLAZA Integrative Orthologychloroplast organization AT2G46340
GO:0009416
IEA
PLAZA Integrative Orthologyresponse to light stimulus AT2G46340
GO:0042752
IEA
PLAZA Integrative Orthologyregulation of circadian rhythm AT2G32950
GO:0009411
IEA
PLAZA Integrative Orthologyresponse to UV AT5G52250
GO:0048856
IEA
PLAZA Integrative Orthologyanatomical structure development AT2G46340
GO:0007154
IEA
PLAZA Integrative Orthologycell communication AT2G46340
GO:0007275
IEA
PLAZA Integrative Orthologymulticellular organism development AT2G46340
GO:1901360
IEA
PLAZA Integrative Orthologyorganic cyclic compound metabolic process AT2G32950
GO:0010224
IEA
PLAZA Integrative Orthologyresponse to UV-B AT5G52250
GO:0010100
IEA
PLAZA Integrative Orthologynegative regulation of photomorphogenesis AT2G46340
GO:0104004
IEA
PLAZA Integrative Orthologycellular response to environmental stimulus AT2G46340
GO:0071489
IEA
PLAZA Integrative Orthologycellular response to red or far red light AT2G46340
GO:0010228
IEA
PLAZA Integrative Orthologyvegetative to reproductive phase transition of meristem AT2G46340
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis AT2G46340
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization AT2G46340
GO:0051098
IEA
PLAZA Integrative Orthologyregulation of binding AT5G52250
GO:0023052
IEA
PLAZA Integrative Orthologysignaling AT2G46340
GO:0048575
IEA
PLAZA Integrative Orthologyshort-day photoperiodism, flowering AT2G46340
GO:0048731
IEA
PLAZA Integrative Orthologysystem development AT2G46340
GO:0009639
IEA
PLAZA Integrative Orthologyresponse to red or far red light AT2G46340
GO:0048572
IEA
PLAZA Integrative Orthologyshort-day photoperiodism AT2G46340
GO:0006725
IEA
PLAZA Integrative Orthologycellular aromatic compound metabolic process AT2G32950
GO:0048573
IEA
PLAZA Integrative Orthologyphotoperiodism, flowering AT2G46340
GO:0071482
IEA
PLAZA Integrative Orthologycellular response to light stimulus AT2G46340
GO:0009646
IEA
PLAZA Integrative Orthologyresponse to absence of light AT2G32950
GO:0065009
IEA
PLAZA Integrative Orthologyregulation of molecular function AT5G52250
GO:0009647
IEA
PLAZA Integrative Orthologyskotomorphogenesis AT2G32950
GO:0006139
IEA
PLAZA Integrative Orthologynucleobase-containing compound metabolic process AT2G32950
GO:0007623
IEA
PLAZA Integrative Orthologycircadian rhythm AT2G32950
GO:0006259
IEA
PLAZA Integrative OrthologyDNA metabolic process AT2G32950
GO:0006974
IEA
PLAZA Integrative Orthologycellular response to DNA damage stimulus AT2G32950
GO:0009648
IEA
PLAZA Integrative Orthologyphotoperiodism AT2G46340
GO:0009641
IEA
PLAZA Integrative Orthologyshade avoidance AT2G32950
GO:0009642
IEA
PLAZA Integrative Orthologyresponse to light intensity AT2G32950
GO:0009640
IEA
PLAZA Integrative Orthologyphotomorphogenesis AT2G46340
GO:0048608
IEA
PLAZA Integrative Orthologyreproductive structure development AT2G46340
GO:0090304
IEA
PLAZA Integrative Orthologynucleic acid metabolic process AT2G32950
GO:0071214
IEA
PLAZA Integrative Orthologycellular response to abiotic stimulus AT2G46340
GO:0051606
IEA
PLAZA Integrative Orthologydetection of stimulus AT2G46340
GO:0010017
IEA
PLAZA Integrative Orthologyred or far-red light signaling pathway AT2G46340
GO:0051241
IEA
PLAZA Integrative Orthologynegative regulation of multicellular organismal process AT2G46340
GO:0043393
IEA
PLAZA Integrative Orthologyregulation of protein binding AT5G52250
GO:0010218
IEA
PLAZA Integrative Orthologyresponse to far red light AT2G46340
GO:0050793
IEA
PLAZA Integrative Orthologyregulation of developmental process AT2G46340
GO:0003006
IEA
PLAZA Integrative Orthologydevelopmental process involved in reproduction AT2G46340
GO:0061458
IEA
PLAZA Integrative Orthologyreproductive system development AT2G46340
GO:0009637
IEA
PLAZA Integrative Orthologyresponse to blue light AT2G46340
GO:0048519
IEA
PLAZA Integrative Orthologynegative regulation of biological process AT2G46340
GO:0051093
IEA
PLAZA Integrative Orthologynegative regulation of developmental process AT2G46340
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development AT2G46340
GO:2000241
IEA
PLAZA Integrative Orthologyregulation of reproductive process AT2G46340
GO:0006281
IEA
PLAZA Integrative OrthologyDNA repair AT2G32950

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0061630
IMP
Genome Projectubiquitin protein ligase activity
GO:0061630
IMP
Gene Ontologyubiquitin protein ligase activity1
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 2 3 4 5 6 7
GO:0004842
TAS
Genome Projectubiquitin-protein transferase activity
GO:0004842
TAS
Gene Ontologyubiquitin-protein transferase activity
GO:0042802
IEA
PLAZA Integrative Orthologyidentical protein binding AT2G46340

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016607
IEA
Genome Projectnuclear speck
GO:0005829
TAS
Genome Projectcytosol
GO:0005829
TAS
Gene Ontologycytosol
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005654
TAS
Gene Ontologynucleoplasm
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0031464
IDA
Gene OntologyCul4A-RING E3 ubiquitin ligase complex2
GO:0000152
IEA
PLAZA Integrative Orthologynuclear ubiquitin ligase complex AT2G32950

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001680WD40 repeat
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR015943WD40/YVTN repeat-like-containing domain superfamily
IPR017907Zinc finger, RING-type, conserved site
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site

No MapMan annotations defined for this gene.
KeggID Description
K10143RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2
No chloroplast target sequence found.