Gene: ENSG00000140398 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000140398
Transcript Identifier
ENST00000569035
Gene Type
Coding gene
Location
15 : 75348906-75355034 : positive

Family Information

Homologous gene family
HOM02SEM000584
(68 genes in 24 species)
specific family

Descriptions

gene_descr
nei endonuclease VIII-like 1 (E. coli)

Identifiers

Type Value
pidENSP00000455730
HGNC18448
UniprotQ96FI4
RefSeq_mRNANM_001256552.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045008
TAS
Genome Projectdepyrimidination
GO:0045008
TAS
Gene Ontologydepyrimidination
GO:0032074
IDA
Genome Projectnegative regulation of nuclease activity
GO:0032074
IDA
Gene Ontologynegative regulation of nuclease activity1
GO:0006979
IDA
Genome Projectresponse to oxidative stress
GO:0006979
IDA
Gene Ontologyresponse to oxidative stress1
GO:0006289
IEA
Genome Projectnucleotide-excision repair
GO:0006284
IDA
Genome Projectbase-excision repair
GO:0006284
IDA
Gene Ontologybase-excision repair1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0019104
TAS
Genome ProjectDNA N-glycosylase activity
GO:0019104
TAS
Gene OntologyDNA N-glycosylase activity
GO:0016798
IDA
Genome Projecthydrolase activity, acting on glycosyl bonds
GO:0016798
IDA
Gene Ontologyhydrolase activity, acting on glycosyl bonds1
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0008022
IPI
Gene Ontologyprotein C-terminus binding1
GO:0003906
TAS
Genome ProjectDNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0003906
TAS
Gene OntologyDNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0003684
IEA
Genome Projectdamaged DNA binding
GO:0097506
IEA
PLAZA Homology (enrichment)deaminated base DNA N-glycosylase activity HOM02SEM000584
GO:0004844
IEA
PLAZA Homology (enrichment)uracil DNA N-glycosylase activity HOM02SEM000584

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm1
GO:0005694
IEA
Genome Projectchromosome
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR010979Ribosomal protein S13-like, H2TH
IPR012319Formamidopyrimidine-DNA glycosylase, catalytic domain
IPR015371Endonuclease VIII-like 1, DNA binding
IPR015886DNA glycosylase/AP lyase, H2TH DNA-binding

No MapMan annotations defined for this gene.
KeggID Description
K10567NEIL1; endonuclease VIII-like 1
No chloroplast target sequence found.