Gene: ENSG00000139174 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000139174
Transcript Identifier
ENST00000552240
Gene Type
Coding gene
Location
12 : 42459809-42472516 : negative

Family Information

Homologous gene family
HOM02SEM005259
(16 genes in 3 species)
specific family
Orthologous gene family
ORTHO02SEM010796
(6 genes in 3 species)
specific family

Descriptions

gene_descr
prickle homolog 1 (Drosophila)

Identifiers

Type Value
pidENSP00000449819
HGNC17019
UniprotQ96MT3
UniprotA0A024R0W7
RefSeq_mRNANM_001144881.1
EMBLCH471111

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:2000691
IDA
Genome Projectnegative regulation of cardiac muscle cell myoblast differentiation
GO:2000691
IDA
Gene Ontologynegative regulation of cardiac muscle cell myoblast differentiation1
GO:0090090
IDA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090090
IDA
Gene Ontologynegative regulation of canonical Wnt signaling pathway2
GO:0060976
IEA
Genome Projectcoronary vasculature development
GO:0060071
TAS, NAS
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0060071
NAS
Gene OntologyWnt signaling pathway, planar cell polarity pathway3
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045892
IDA
Gene Ontologynegative regulation of transcription, DNA-templated2
GO:0035904
IEA
Genome Projectaorta development
GO:0032436
IDA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032436
IDA
Gene Ontologypositive regulation of proteasomal ubiquitin-dependent protein catabolic process2
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031398
IDA
Gene Ontologypositive regulation of protein ubiquitination2
GO:0006606
IDA, IMP
Genome Projectprotein import into nucleus
GO:0006606
IDA, IMP
Gene Ontologyprotein import into nucleus1 4 5
GO:0001843
IMP
Genome Projectneural tube closure
GO:0001843
IMP
Gene Ontologyneural tube closure6
GO:0030951
IEA
PLAZA Integrative Orthologyestablishment or maintenance of microtubule cytoskeleton polarity FBgn0003090
GO:0030952
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cytoskeleton polarity FBgn0003090
GO:0010720
IEA
PLAZA Integrative Orthologypositive regulation of cell development FBgn0003090
GO:0001737
IEA
PLAZA Integrative Orthologyestablishment of imaginal disc-derived wing hair orientation FBgn0003090
GO:0048592
IEA
PLAZA Integrative Orthologyeye morphogenesis FBgn0003090
GO:0051235
IEA
PLAZA Integrative Orthologymaintenance of location FBgn0003090
GO:1902669
IEA
PLAZA Integrative Orthologypositive regulation of axon guidance FBgn0003090
GO:0048749
IEA
PLAZA Integrative Orthologycompound eye development FBgn0003090
GO:0003002
IEA
PLAZA Integrative Orthologyregionalization FBgn0003090
GO:0006996
IEA
PLAZA Integrative Orthologyorganelle organization FBgn0003090
GO:0048589
IEA
PLAZA Integrative Orthologydevelopmental growth FBgn0003090
GO:0048468
IEA
PLAZA Integrative Orthologycell development FBgn0263934
GO:0045597
IEA
PLAZA Integrative Orthologypositive regulation of cell differentiation FBgn0003090
GO:0007444
IEA
PLAZA Integrative Orthologyimaginal disc development FBgn0003090
GO:1902667
IEA
PLAZA Integrative Orthologyregulation of axon guidance FBgn0003090
GO:0007163
IEA
PLAZA Integrative Orthologyestablishment or maintenance of cell polarity FBgn0003090
GO:0007560
IEA
PLAZA Integrative Orthologyimaginal disc morphogenesis FBgn0003090
GO:0061387
IEA
PLAZA Integrative Orthologyregulation of extent of cell growth FBgn0003090
GO:0032101
IEA
PLAZA Integrative Orthologyregulation of response to external stimulus FBgn0003090
GO:0035218
IEA
PLAZA Integrative Orthologyleg disc development FBgn0003090
GO:0032103
IEA
PLAZA Integrative Orthologypositive regulation of response to external stimulus FBgn0003090
GO:0050770
IEA
PLAZA Integrative Orthologyregulation of axonogenesis FBgn0003090
GO:0048588
IEA
PLAZA Integrative Orthologydevelopmental cell growth FBgn0003090
GO:0009605
IEA
PLAZA Integrative Orthologyresponse to external stimulus FBgn0003090
GO:0032989
IEA
PLAZA Integrative Orthologycellular component morphogenesis FBgn0003090
GO:0050772
IEA
PLAZA Integrative Orthologypositive regulation of axonogenesis FBgn0003090
GO:0048584
IEA
PLAZA Integrative Orthologypositive regulation of response to stimulus FBgn0003090
GO:0048736
IEA
PLAZA Integrative Orthologyappendage development FBgn0003090
GO:0048858
IEA
PLAZA Integrative Orthologycell projection morphogenesis FBgn0003090
GO:0048737
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage development FBgn0003090
GO:0045746
IEA
PLAZA Integrative Orthologynegative regulation of Notch signaling pathway FBgn0003090
GO:0007552
IEA
PLAZA Integrative Orthologymetamorphosis FBgn0003090
GO:0048699
IEA
PLAZA Integrative Orthologygeneration of neurons FBgn0263934
GO:0090596
IEA
PLAZA Integrative Orthologysensory organ morphogenesis FBgn0003090
GO:0008361
IEA
PLAZA Integrative Orthologyregulation of cell size FBgn0003090
GO:0008088
IEA
PLAZA Integrative Orthologyaxo-dendritic transport FBgn0003090
GO:0032990
IEA
PLAZA Integrative Orthologycell part morphogenesis FBgn0003090
GO:0035220
IEA
PLAZA Integrative Orthologywing disc development FBgn0003090
GO:0016049
IEA
PLAZA Integrative Orthologycell growth FBgn0003090
GO:0050921
IEA
PLAZA Integrative Orthologypositive regulation of chemotaxis FBgn0003090
GO:0050767
IEA
PLAZA Integrative Orthologyregulation of neurogenesis FBgn0003090
GO:0050920
IEA
PLAZA Integrative Orthologyregulation of chemotaxis FBgn0003090
GO:0050769
IEA
PLAZA Integrative Orthologypositive regulation of neurogenesis FBgn0003090
GO:0071840
IEA
PLAZA Integrative Orthologycellular component organization or biogenesis FBgn0003090
GO:0016043
IEA
PLAZA Integrative Orthologycellular component organization FBgn0003090
GO:0035107
IEA
PLAZA Integrative Orthologyappendage morphogenesis FBgn0003090
GO:0070593
IEA
PLAZA Integrative Orthologydendrite self-avoidance FBgn0263934
GO:0006928
IEA
PLAZA Integrative Orthologymovement of cell or subcellular component FBgn0003090
GO:0032879
IEA
PLAZA Integrative Orthologyregulation of localization FBgn0003090
GO:0007219
IEA
PLAZA Integrative OrthologyNotch signaling pathway FBgn0003090
GO:0009913
IEA
PLAZA Integrative Orthologyepidermal cell differentiation FBgn0003090
GO:0045185
IEA
PLAZA Integrative Orthologymaintenance of protein location FBgn0003090
GO:0030855
IEA
PLAZA Integrative Orthologyepithelial cell differentiation FBgn0003090
GO:0042067
IEA
PLAZA Integrative Orthologyestablishment of ommatidial planar polarity FBgn0003090
GO:0042221
IEA
PLAZA Integrative Orthologyresponse to chemical FBgn0003090
GO:0048569
IEA
PLAZA Integrative Orthologypost-embryonic animal organ development FBgn0003090
GO:0008037
IEA
PLAZA Integrative Orthologycell recognition FBgn0263934
GO:0009886
IEA
PLAZA Integrative Orthologypost-embryonic animal morphogenesis FBgn0003090
GO:0008038
IEA
PLAZA Integrative Orthologyneuron recognition FBgn0263934
GO:0030182
IEA
PLAZA Integrative Orthologyneuron differentiation FBgn0263934
GO:0010970
IEA
PLAZA Integrative Orthologytransport along microtubule FBgn0003090
GO:0035114
IEA
PLAZA Integrative Orthologyimaginal disc-derived appendage morphogenesis FBgn0003090
GO:0010975
IEA
PLAZA Integrative Orthologyregulation of neuron projection development FBgn0003090
GO:0010976
IEA
PLAZA Integrative Orthologypositive regulation of neuron projection development FBgn0003090
GO:0098930
IEA
PLAZA Integrative Orthologyaxonal transport FBgn0003090
GO:0048563
IEA
PLAZA Integrative Orthologypost-embryonic animal organ morphogenesis FBgn0003090
GO:0001745
IEA
PLAZA Integrative Orthologycompound eye morphogenesis FBgn0003090
GO:0051960
IEA
PLAZA Integrative Orthologyregulation of nervous system development FBgn0003090
GO:0051962
IEA
PLAZA Integrative Orthologypositive regulation of nervous system development FBgn0003090
GO:0099111
IEA
PLAZA Integrative Orthologymicrotubule-based transport FBgn0003090
GO:0002165
IEA
PLAZA Integrative Orthologyinstar larval or pupal development FBgn0003090
GO:0008544
IEA
PLAZA Integrative Orthologyepidermis development FBgn0003090
GO:0042330
IEA
PLAZA Integrative Orthologytaxis FBgn0003090
GO:0035120
IEA
PLAZA Integrative Orthologypost-embryonic appendage morphogenesis FBgn0003090
GO:0060560
IEA
PLAZA Integrative Orthologydevelopmental growth involved in morphogenesis FBgn0003090
GO:0060284
IEA
PLAZA Integrative Orthologyregulation of cell development FBgn0003090
GO:0120039
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection morphogenesis FBgn0003090
GO:0022604
IEA
PLAZA Integrative Orthologyregulation of cell morphogenesis FBgn0003090
GO:0120036
IEA
PLAZA Integrative Orthologyplasma membrane bounded cell projection organization FBgn0003090
GO:0120035
IEA
PLAZA Integrative Orthologyregulation of plasma membrane bounded cell projection organization FBgn0003090
GO:0032535
IEA
PLAZA Integrative Orthologyregulation of cellular component size FBgn0003090
GO:0048675
IEA
PLAZA Integrative Orthologyaxon extension FBgn0003090
GO:0010769
IEA
PLAZA Integrative Orthologyregulation of cell morphogenesis involved in differentiation FBgn0003090
GO:0030516
IEA
PLAZA Integrative Orthologyregulation of axon extension FBgn0003090
GO:0001654
IEA
PLAZA Integrative Orthologyeye development FBgn0003090
GO:0048666
IEA
PLAZA Integrative Orthologyneuron development FBgn0263934
GO:0048667
IEA
PLAZA Integrative Orthologycell morphogenesis involved in neuron differentiation FBgn0003090
GO:0031175
IEA
PLAZA Integrative Orthologyneuron projection development FBgn0003090
GO:0048707
IEA
PLAZA Integrative Orthologyinstar larval or pupal morphogenesis FBgn0003090
GO:0010770
IEA
PLAZA Integrative Orthologypositive regulation of cell morphogenesis involved in differentiation FBgn0003090
GO:0007480
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg morphogenesis FBgn0003090
GO:0006935
IEA
PLAZA Integrative Orthologychemotaxis FBgn0003090
GO:0040017
IEA
PLAZA Integrative Orthologypositive regulation of locomotion FBgn0003090
GO:0007478
IEA
PLAZA Integrative Orthologyleg disc morphogenesis FBgn0003090
GO:0051270
IEA
PLAZA Integrative Orthologyregulation of cellular component movement FBgn0003090
GO:0045664
IEA
PLAZA Integrative Orthologyregulation of neuron differentiation FBgn0003090
GO:0051272
IEA
PLAZA Integrative Orthologypositive regulation of cellular component movement FBgn0003090
GO:0045666
IEA
PLAZA Integrative Orthologypositive regulation of neuron differentiation FBgn0003090
GO:0007476
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing morphogenesis FBgn0003090
GO:0048812
IEA
PLAZA Integrative Orthologyneuron projection morphogenesis FBgn0003090
GO:0040011
IEA
PLAZA Integrative Orthologylocomotion FBgn0003090
GO:0040012
IEA
PLAZA Integrative Orthologyregulation of locomotion FBgn0003090
GO:0007472
IEA
PLAZA Integrative Orthologywing disc morphogenesis FBgn0003090
GO:0016348
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg joint morphogenesis FBgn0003090
GO:0031346
IEA
PLAZA Integrative Orthologypositive regulation of cell projection organization FBgn0003090
GO:0031344
IEA
PLAZA Integrative Orthologyregulation of cell projection organization FBgn0003090
GO:0051130
IEA
PLAZA Integrative Orthologypositive regulation of cellular component organization FBgn0003090
GO:1990138
IEA
PLAZA Integrative Orthologyneuron projection extension FBgn0003090
GO:0001558
IEA
PLAZA Integrative Orthologyregulation of cell growth FBgn0003090
GO:0150063
IEA
PLAZA Integrative Orthologyvisual system development FBgn0003090
GO:0040007
IEA
PLAZA Integrative Orthologygrowth FBgn0003090
GO:0007423
IEA
PLAZA Integrative Orthologysensory organ development FBgn0003090
GO:0040008
IEA
PLAZA Integrative Orthologyregulation of growth FBgn0003090
GO:0000226
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton organization FBgn0003090
GO:0045773
IEA
PLAZA Integrative Orthologypositive regulation of axon extension FBgn0003090
GO:0090066
IEA
PLAZA Integrative Orthologyregulation of anatomical structure size FBgn0003090
GO:0007389
IEA
PLAZA Integrative Orthologypattern specification process FBgn0003090
GO:0000902
IEA
PLAZA Integrative Orthologycell morphogenesis FBgn0003090
GO:0008593
IEA
PLAZA Integrative Orthologyregulation of Notch signaling pathway FBgn0003090
GO:0000904
IEA
PLAZA Integrative Orthologycell morphogenesis involved in differentiation FBgn0003090
GO:0061564
IEA
PLAZA Integrative Orthologyaxon development FBgn0003090
GO:0065008
IEA
PLAZA Integrative Orthologyregulation of biological quality FBgn0003090
GO:0035315
IEA
PLAZA Integrative Orthologyhair cell differentiation FBgn0003090
GO:0051128
IEA
PLAZA Integrative Orthologyregulation of cellular component organization FBgn0003090
GO:0035317
IEA
PLAZA Integrative Orthologyimaginal disc-derived wing hair organization FBgn0003090
GO:0035316
IEA
PLAZA Integrative Orthologynon-sensory hair organization FBgn0003090
GO:0051240
IEA
PLAZA Integrative Orthologypositive regulation of multicellular organismal process FBgn0003090
GO:0007409
IEA
PLAZA Integrative Orthologyaxonogenesis FBgn0003090
GO:0030705
IEA
PLAZA Integrative Orthologycytoskeleton-dependent intracellular transport FBgn0003090
GO:0030307
IEA
PLAZA Integrative Orthologypositive regulation of cell growth FBgn0003090
GO:0009948
IEA
PLAZA Integrative Orthologyanterior/posterior axis specification FBgn0003090
GO:0048880
IEA
PLAZA Integrative Orthologysensory system development FBgn0003090
GO:0097485
IEA
PLAZA Integrative Orthologyneuron projection guidance FBgn0003090
GO:0007017
IEA
PLAZA Integrative Orthologymicrotubule-based process FBgn0003090
GO:0048638
IEA
PLAZA Integrative Orthologyregulation of developmental growth FBgn0003090
GO:0048639
IEA
PLAZA Integrative Orthologypositive regulation of developmental growth FBgn0003090
GO:0007018
IEA
PLAZA Integrative Orthologymicrotubule-based movement FBgn0003090
GO:0051094
IEA
PLAZA Integrative Orthologypositive regulation of developmental process FBgn0003090
GO:0022008
IEA
PLAZA Integrative Orthologyneurogenesis FBgn0263934
GO:0007411
IEA
PLAZA Integrative Orthologyaxon guidance FBgn0003090
GO:0009952
IEA
PLAZA Integrative Orthologyanterior/posterior pattern specification FBgn0003090
GO:0009798
IEA
PLAZA Integrative Orthologyaxis specification FBgn0003090
GO:0030030
IEA
PLAZA Integrative Orthologycell projection organization FBgn0003090
GO:0036011
IEA
PLAZA Integrative Orthologyimaginal disc-derived leg segmentation FBgn0003090
GO:0035285
IEA
PLAZA Integrative Orthologyappendage segmentation FBgn0003090
GO:0009791
IEA
PLAZA Integrative Orthologypost-embryonic development FBgn0003090
GO:0007010
IEA
PLAZA Integrative Orthologycytoskeleton organization FBgn0003090
GO:0035282
IEA
PLAZA Integrative Orthologysegmentation FBgn0003090
GO:0045927
IEA
PLAZA Integrative Orthologypositive regulation of growth FBgn0003090

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding2 4 5 7 8 9 10

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031965
IDA
Genome Projectnuclear membrane
GO:0031965
IDA
Gene Ontologynuclear membrane4 5
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol4 7
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus4 5 7
GO:0044430
IEA
PLAZA Integrative Orthologycytoskeletal part ENSG00000012211
GO:0005815
IEA
PLAZA Integrative Orthologymicrotubule organizing center ENSG00000012211
GO:0005813
IEA
PLAZA Integrative Orthologycentrosome ENSG00000012211
GO:0015630
IEA
PLAZA Integrative Orthologymicrotubule cytoskeleton ENSG00000012211
GO:0071944
IEA
PLAZA Integrative Orthologycell periphery FBgn0003090
GO:0005856
IEA
PLAZA Integrative Orthologycytoskeleton ENSG00000012211
GO:0005886
IEA
PLAZA Integrative Orthologyplasma membrane FBgn0003090
GO:0043232
IEA
PLAZA Integrative Orthologyintracellular non-membrane-bounded organelle ENSG00000012211
GO:0043228
IEA
PLAZA Integrative Orthologynon-membrane-bounded organelle ENSG00000012211

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001781Zinc finger, LIM-type
IPR010442PET domain
IPR033723PET prickle
IPR033726LIM2 prickle
IPR033727LIM3 prickle

No MapMan annotations defined for this gene.
KeggID Description
K04511PRICKLE; prickle
No chloroplast target sequence found.