Gene: ENSG00000137497 (Homo sapiens)

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Gene Identifier
ENSG00000137497
Transcript Identifier
ENST00000393695
Gene Type
Coding gene
Location
11 : 72003527-72035943 : negative

Family Information

Homologous gene family
HOM02SEM062834
(orphan gene)
specific family

Descriptions

gene_descr
nuclear mitotic apparatus protein 1

Identifiers

Type Value
pidENSP00000377298
HGNC8059
UniprotQ14980
RefSeq_mRNANM_006185.3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1905832
IMP
Genome Projectpositive regulation of spindle assembly
GO:1905832
IMP
Gene Ontologypositive regulation of spindle assembly1
GO:1905820
IMP
Genome Projectpositive regulation of chromosome separation
GO:1905820
IMP
Gene Ontologypositive regulation of chromosome separation2
GO:1904778
IMP
Genome Projectpositive regulation of protein localization to cell cortex
GO:1904778
IMP
Gene Ontologypositive regulation of protein localization to cell cortex2 3 4 5 6 7
GO:1902846
IMP
Genome Projectpositive regulation of mitotic spindle elongation
GO:1902846
IMP
Gene Ontologypositive regulation of mitotic spindle elongation2
GO:1902365
IDA
Genome Projectpositive regulation of protein localization to spindle pole body
GO:1902365
IDA
Gene Ontologypositive regulation of protein localization to spindle pole body8
GO:0090235
IMP
Genome Projectregulation of metaphase plate congression
GO:0090235
IMP
Gene Ontologyregulation of metaphase plate congression1
GO:0060487
IEA
Genome Projectlung epithelial cell differentiation
GO:0060236
IDA, IMP
Genome Projectregulation of mitotic spindle organization
GO:0060236
IDA, IMP
Gene Ontologyregulation of mitotic spindle organization4 6 9 10 11
GO:0055048
IMP
Genome Projectanastral spindle assembly
GO:0055048
IMP
Gene Ontologyanastral spindle assembly12
GO:0051984
IMP
Genome Projectpositive regulation of chromosome segregation
GO:0051984
IMP
Gene Ontologypositive regulation of chromosome segregation6
GO:0051798
ISS
Genome Projectpositive regulation of hair follicle development
GO:0051798
ISS
Gene Ontologypositive regulation of hair follicle development
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0051301
IEA
Genome Projectcell division
GO:0045618
ISS
Genome Projectpositive regulation of keratinocyte differentiation
GO:0045618
ISS
Gene Ontologypositive regulation of keratinocyte differentiation
GO:0032388
IMP
Genome Projectpositive regulation of intracellular transport
GO:0032388
IMP
Gene Ontologypositive regulation of intracellular transport1
GO:0031116
IMP
Genome Projectpositive regulation of microtubule polymerization
GO:0031116
IMP
Gene Ontologypositive regulation of microtubule polymerization13
GO:0030953
IDA, IMP
Genome Projectastral microtubule organization
GO:0030953
IDA, IMP
Gene Ontologyastral microtubule organization13
GO:0030513
ISS
Genome Projectpositive regulation of BMP signaling pathway
GO:0030513
ISS
Gene Ontologypositive regulation of BMP signaling pathway
GO:0006997
TAS
Genome Projectnucleus organization
GO:0006997
TAS
Gene Ontologynucleus organization14
GO:0001578
IMP
Genome Projectmicrotubule bundle formation
GO:0001578
IMP
Gene Ontologymicrotubule bundle formation13
GO:0000132
IDA, IMP
ISS
Genome Projectestablishment of mitotic spindle orientation
GO:0000132
IDA, IMP
ISS
Gene Ontologyestablishment of mitotic spindle orientation7 15 16

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0097718
IMP
Genome Projectdisordered domain specific binding
GO:0097718
IMP
Gene Ontologydisordered domain specific binding17
GO:0070840
IDA
Genome Projectdynein complex binding
GO:0070840
IDA
Gene Ontologydynein complex binding3 4 10 11 18
GO:0051011
IDA
Genome Projectmicrotubule minus-end binding
GO:0051011
IDA
Gene Ontologymicrotubule minus-end binding16
GO:0051010
IDA
Genome Projectmicrotubule plus-end binding
GO:0051010
IDA
Gene Ontologymicrotubule plus-end binding16
GO:0035091
IDA
Genome Projectphosphatidylinositol binding
GO:0035091
IDA
Gene Ontologyphosphatidylinositol binding6 7
GO:0015631
IDA
Genome Projecttubulin binding
GO:0015631
IDA
Gene Ontologytubulin binding9
GO:0008022
IMP
Genome Projectprotein C-terminus binding
GO:0008022
IMP
Gene Ontologyprotein C-terminus binding17
GO:0008017
IDA
Genome Projectmicrotubule binding
GO:0008017
IDA
Gene Ontologymicrotubule binding1 9 13
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IPI
Gene Ontologyprotein binding1 3 5 7 8 10 11 13 15 17 19 20 21 22 23 24
GO:0005198
TAS
Genome Projectstructural molecule activity
GO:0005198
TAS
Gene Ontologystructural molecule activity14
GO:0044877
IDA
Gene Ontologyprotein-containing complex binding19
GO:0019904
IPI
Gene Ontologyprotein domain specific binding25

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:1990023
IDA
Genome Projectmitotic spindle midzone
GO:1990023
IDA
Gene Ontologymitotic spindle midzone18
GO:1905720
IDA
Genome Projectcytoplasmic microtubule bundle
GO:1905720
IDA
Gene Ontologycytoplasmic microtubule bundle13
GO:0099738
IDA
Genome Projectcell cortex region
GO:0099738
IDA
Gene Ontologycell cortex region2 3 5 6 7 15
GO:0097431
IDA, IMP
Genome Projectmitotic spindle pole
GO:0097431
IDA, IMP
Gene Ontologymitotic spindle pole1 3 5 6 7 8 9 10 11 12 15 18 20 26 27 28
GO:0097427
IDA
Genome Projectmicrotubule bundle
GO:0097427
IDA
Gene Ontologymicrotubule bundle9
GO:0072686
IDA
Genome Projectmitotic spindle
GO:0072686
IDA
Gene Ontologymitotic spindle1 18 29
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0070062
Gene Ontologyextracellular exosome30
GO:0061673
IDA
Genome Projectmitotic spindle astral microtubule
GO:0061673
IDA
Gene Ontologymitotic spindle astral microtubule7 13 18 26 29
GO:0055028
IDA
Genome Projectcortical microtubule
GO:0055028
IDA
Gene Ontologycortical microtubule16
GO:0045177
IEA
Genome Projectapical part of cell
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0036449
IDA
Genome Projectmicrotubule minus-end
GO:0036449
IDA
Gene Ontologymicrotubule minus-end16
GO:0035371
IDA
Genome Projectmicrotubule plus-end
GO:0035371
IDA
Gene Ontologymicrotubule plus-end16
GO:0031616
IDA
Genome Projectspindle pole centrosome
GO:0031616
IDA
Gene Ontologyspindle pole centrosome18
GO:0030425
IEA
Genome Projectdendrite
GO:0019897
IDA
Genome Projectextrinsic component of plasma membrane
GO:0019897
IDA
Gene Ontologyextrinsic component of plasma membrane6 7
GO:0016363
IDA
Genome Projectnuclear matrix
GO:0016363
IDA
Gene Ontologynuclear matrix9 27
GO:0005938
IDA
Genome Projectcell cortex
GO:0005938
IDA
Gene Ontologycell cortex28
GO:0005876
IDA
Genome Projectspindle microtubule
GO:0005876
IDA
Gene Ontologyspindle microtubule26
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005829
IDA
TAS
Gene Ontologycytosol
GO:0005819
TAS
Genome Projectspindle
GO:0005819
TAS
Gene Ontologyspindle31
GO:0005813
IDA
Genome Projectcentrosome
GO:0005813
IDA
Gene Ontologycentrosome12 16 29
GO:0005694
IEA
Genome Projectchromosome
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005654
IDA
TAS
Gene Ontologynucleoplasm18
GO:0005634
IDA
Genome Projectnucleus
GO:0005634
IDA
Gene Ontologynucleus1 2 26
GO:0000922
IDA
Genome Projectspindle pole
GO:0000922
IDA
Gene Ontologyspindle pole2 32 33
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0097575
ISS
Gene Ontologylateral cell cortex
GO:0032991
IDA, IMP
Gene Ontologyprotein-containing complex17 25

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR026650Nuclear mitotic apparatus protein 1

No MapMan annotations defined for this gene.
KeggID Description
K16808NUMA1; nuclear mitotic apparatus protein 1
No chloroplast target sequence found.